Histoplasma capsulatum fails to trigger release of superoxide from macrophages.

abstract：:We characterized outer membrane proteins (OMPs) from selected Campylobacter jejuni, C. coli, and C. fetus strains by two-dimensional gel electrophoresis (2DGE), using isoelectric focusing and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), and by immunoblotting with immune rabbit serum. The flage...

journal_title：Infection and immunity

authors： Dunn BE,Blaser MJ,Snyder EL

更新日期：1987-07-01 00:00:00

abstract：:A peptidoglycan layer of Treponema pallidum kazan was isolated by solubilization of whole cells with 1% warm sodium dodecyl sulfate and subsequent digestion of an insoluble residue with proteases. Electron microscopy revealed that the peptidoglycan was isolated as a single-layered sacculus of less than 5 nm in thickne...

journal_title：Infection and immunity

authors： Umemoto T,Ota T,Sagawa H,Kato K,Takada H,Tsujimoto M,Kawasaki A,Ogawa T,Harada K,Kotani S

更新日期：1981-02-01 00:00:00

abstract：:Wild-type isolates of Shigella flexneri bind the dye Congo red from solid media, thus producing red (Crb+) colonies. Mutants which fail to bind the dye produce white colonies (Crb-) and are avirulent in a variety of systems. In S. flexneri the ability to bind Congo red correlates with the ability to bind hemin and pro...

journal_title：Infection and immunity

authors： Daskaleros PA,Payne SM

更新日期：1987-06-01 00:00:00

abstract：:In the enteric pathogen Vibrio cholerae, expression of the major virulence factors is controlled by the hierarchical expression of several regulatory proteins comprising the ToxR regulon. In this study, we demonstrate that disruption of the fadD gene encoding a long-chain fatty acyl coenzyme A ligase has marked effect...

journal_title：Infection and immunity

authors： Ray S,Chatterjee E,Chatterjee A,Paul K,Chowdhury R

更新日期：2011-01-01 00:00:00

abstract：:There are no vaccines against boutonneuse fever and Rocky Mountain spotted fever. Previous studies have identified a Rickettsia rickettsii surface protein as a vaccine candidate and shown that an antigenically related protein is present in R. conorii, which causes boutonneuse fever. The gene encoding the R. rickettsii...

journal_title：Infection and immunity

authors： Vishwanath S,McDonald GA,Watkins NG

更新日期：1990-03-01 00:00:00

abstract：:Time-lapse cinematography was used to study the growth cycle of Chlamydia trachomatis in primary cell cultures of human amnion. Twelve preterm and twelve term placentas were obtained within 8 h of delivery, and epithelial cells were dissociated from the amniotic membranes by trypsinization and grown in Rose chambers. ...

journal_title：Infection and immunity

authors： Neeper ID,Patton DL,Kuo CC

更新日期：1990-07-01 00:00:00

abstract：:Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized by a strong Th1 response that leads to skin lesion development. In areas where L. braziliensis transmission is endemic, up to 15% of healthy subjects have tested positive for delayed-type hypersensitivity to soluble leishmania antigen (SLA...

journal_title：Infection and immunity

authors： Cardoso TM,Machado Á,Costa DL,Carvalho LP,Queiroz A,Machado P,Scott P,Carvalho EM,Bacellar O

更新日期：2015-03-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) glycoprotein gC was purified by affinity chromatography with an immunosorbent column containing monoclonal antibody to HSV-1 gC, and its reactivity with rabbit antisera was measured by enzyme-linked immunosorbent assay and sodium dodecyl sulfate-polyacrylamide gel electrophoretic an...

journal_title：Infection and immunity

authors： Zweig M,Heilman CJ Jr,Bladen SV,Showalter SD,Hampar B

更新日期：1983-08-01 00:00:00

abstract：:Streptococcus suis is one of the most important pathogens affecting the swine industry and is also an emerging zoonotic agent for humans. Two-component signaling systems (TCSs) play important roles in the adaptation of pathogenic bacteria to host environments. In this study, we identified a novel TCS, named TCS09HKRR,...

journal_title：Infection and immunity

authors： Zhong X,Zhang Y,Zhu Y,Dong W,Ma J,Pan Z,Yao H

更新日期：2019-08-21 00:00:00

abstract：:Natural heterogeneity in the structure of the lipid A portion of lipopolysaccharide (LPS) produces differential effects on the innate immune response. Gram-negative bacterial species produce LPS structures that differ from the classic endotoxic LPS structures. These differences include hypoacylation and hypophosphoryl...

journal_title：Infection and immunity

authors： Chilton PM,Hadel DM,To TT,Mitchell TC,Darveau RP

更新日期：2013-09-01 00:00:00

abstract：:The essential role of T cells in the resolution of primary murine Chlamydia trachomatis genital tract infection is inarguable; however, much less is known about the mechanisms that confer resistance to reinfection. We previously established that CD4+ T cells and B cells contribute importantly to resistance to reinfect...

journal_title：Infection and immunity

authors： Morrison SG,Morrison RP

更新日期：2001-04-01 00:00:00

abstract：:Highly purified protein antigens are usually poor immunogens; in practice, adjuvants are needed to obtain satisfactory immune responses. Plasmodium yoelii 19-kDa merozoite surface protein 1 (MSP1(19)) is a weak antigen, but mice vaccinated with this antigen in strong adjuvants can survive an otherwise lethal parasite ...

journal_title：Infection and immunity

authors： Ogun SA,Dumon-Seignovert L,Marchand JB,Holder AA,Hill F

更新日期：2008-08-01 00:00:00

abstract：:Using a PCR-based strategy and degenerate oligonucleotides, we isolated a Legionella pneumophila gene that showed high sequence similarity to members of the fliI gene family. An insertion mutation that disrupted the fliI open reading frame was recombined onto the L. pneumophila chromosome and analyzed for its effects ...

journal_title：Infection and immunity

authors： Merriam JJ,Mathur R,Maxfield-Boumil R,Isberg RR

更新日期：1997-06-01 00:00:00

abstract：:The immune response of humans and mice to temperature-specific, plasmid- or chromosome-encoded proteins of yersinia pestis and Yersinia enterocolitica was investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting. Extracts from Y. pestis and Y. enterocolitica strains with and witho...

journal_title：Infection and immunity

authors： Mazza G,Karu AE,Kingsbury DT

更新日期：1985-06-01 00:00:00

abstract：:We have previously shown that Bacillus anthracis lethal toxin represses glucocorticoid receptor (GR) transactivation. We now report that repression of GR activity also occurs with the large clostridial toxins produced by Clostridium sordellii and C. difficile. This was demonstrated using a transient transfection assay...

journal_title：Infection and immunity

authors： Tait AS,Dalton M,Geny B,D'Agnillo F,Popoff MR,Sternberg EM

更新日期：2007-08-01 00:00:00

abstract：:To demonstrate local synthesis of anti-Mycobacterium leprae antibodies, biopsies from skin lesions of leprosy patients were cultured in vitro in a medium containing 14C-labeled lysine and isoleucine, and the culture fluids were analyzed by crossed immunoelectrophoresis with intermediate gel and autoradiography. The re...

journal_title：Infection and immunity

authors： Lai A Fat RF,Chan Pin Jin J,van Furth R,Harboe M

更新日期：1980-02-01 00:00:00

abstract：:We have isolated plasma cell hybridomas which secrete monoclonal antibodies directed against Haemophilus ducreyi. Two of these monoclonal antibodies recognize all strains of H. ducreyi tested to date and are capable of detecting the presence of H. ducreyi in skin lesions produced by this pathogen in experimental anima...

journal_title：Infection and immunity

authors： Hansen EJ,Loftus TA

更新日期：1984-04-01 00:00:00

abstract：:Strains of Cryptococcus neoformans vary in resistance to phagocytosis in vitro. The binding of isolated capsular polysaccharide (CPS) to a capsule-free mutant of C. neoformans confers resistance to phagocytosis. The importance of capsule composition to differences among strains in susceptibility to phagocytosis was ev...

journal_title：Infection and immunity

authors： Small JM,Mitchell TG

更新日期：1989-12-01 00:00:00

abstract：:Immunochemical analyses of soluble antigens derived from microaerophilous stationary phase cultures of Babesia bovis demonstrated that at least three parasite antigens were released in vitro. These antigens have molecular weights within the range of 37,000 to 40,000, fast electrophoretic mobility in the albumin and al...

journal_title：Infection and immunity

authors： James MA,Levy MG,Ristic M

更新日期：1981-01-01 00:00:00

abstract：:Athymic nude mice (nu/nu), heterozygous litter mates (nu/+), and thymic reconstituted homozygous animals (nu/nu TxR) were infected with Trypanosoma rhodesiense. A reduced parasitemia and prolonged survival were observed in the nu/nu animals after infection and cure or after immunization with irradiated organisms. Thes...

journal_title：Infection and immunity

authors： Campbell GH,Esser KM,Phillips SM

更新日期：1978-06-01 00:00:00

abstract：:Potassium thiocyanate extracts of a virulent Pasteurella multocida 3:A rabbit isolate were prepared and used as a vaccine in rabbits. The extract contained protein, carbohydrate, hyaluronic acid, lipopolysaccharide, DNA, and RNA. The protein and lipopolysaccharide profiles of the extract were similar to those of the P...

journal_title：Infection and immunity

authors： Lu YS,Pakes SP,Massey L,Stefanu C

更新日期：1987-12-01 00:00:00

abstract：:Strategies to limit complement deposition on Streptococcus pneumoniae are established as virulence features for invasive disease, but their role in respiratory tract infection requires further analysis. We evaluated complement C3 protein deposition on discordant S. pneumoniae isolates of the same serotype (6A) and the...

journal_title：Infection and immunity

authors： Sabharwal V,Ram S,Figueira M,Park IH,Pelton SI

更新日期：2009-03-01 00:00:00

abstract：:Heat shock protein (HSP) expression was examined in murine bone marrow-derived macrophages infected with stationary-phase promastigotes of Leishmania donovani. Immunoblotting performed with a rabbit polyclonal antiserum raised against HSP60 from Heliothis virescens (moth) revealed the de novo appearance of 65- and 67-...

journal_title：Infection and immunity

authors： Rey-Ladino JA,Reiner NE

更新日期：1993-08-01 00:00:00

abstract：:Harvard caries-resistant rats (CR) monoassociated with cariogenic Streptococcus faecalis (SF) for 150 days developed early high levels of specific SF serum agglutinins, moderate levels of salivary antibody, and little or no caries activity. Harvard caries-susceptible (CS) SF-monoassociated rats developed serum antibod...

journal_title：Infection and immunity

authors： Peri BA,Wagner M

更新日期：1977-06-01 00:00:00

abstract：:In this study, we report on a novel approach based on modification of the intestinal surface to prevent diarrhea caused by enterotoxigenic Escherichia coli (ETEC). The removable intestinal tie adult rabbit diarrhea (RITARD) model was used to test the efficacy of an enteric-coated protease preparation (Detach; Enzacor ...

journal_title：Infection and immunity

authors： Mynott TL,Chandler DS,Luke RK

更新日期：1991-10-01 00:00:00

abstract：:An antigen recognized by monoclonal antibody specific for Bacteroides gingivalis was purified in the presence of 0.5% (wt/vol) beta-octyl-glucoside by immunoadsorbent column chromatography. The purified antigen was homogeneous as judged by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and silver...

journal_title：Infection and immunity

authors： Miyoshi T,Hanazawa S,Hirose K,Saitoh K,Amano S,Ohmori Y,Kitano S

更新日期：1986-08-01 00:00:00

abstract：:Enterococcus faecalis is a highly stress resistant opportunistic pathogen. The intrinsic ruggedness of this bacterium is supposed to be the basis of its capacity to colonize the hostile environments of hospitals and to cause several kinds of infections. We show in this work that general resistance to very different en...

journal_title：Infection and immunity

authors： Rana NF,Sauvageot N,Laplace JM,Bao Y,Nes I,Rincé A,Posteraro B,Sanguinetti M,Hartke A

更新日期：2013-08-01 00:00:00

abstract：:During acute infection with bacteria, viruses or parasites, a fraction of macrophages engulf large numbers of red and white blood cells, a process called hemophagocytosis. Hemophagocytes persist into the chronic stage of infection and have an anti-inflammatory phenotype. Salmonella enterica serovar Typhimurium infecti...

journal_title：Infection and immunity

authors： McDonald EM,Pilonieta MC,Nick HJ,Detweiler CS

更新日期：2015-10-12 00:00:00

abstract：:Adherence of erythrocytes infected with Plasmodium falciparum to microvascular endothelial cells (sequestration) is considered to play an important role in parasite virulence and pathogenesis. However, the real importance of sequestration for infection and disease has never been fully assessed. The absence of an appro...

journal_title：Infection and immunity

authors： Mota MM,Jarra W,Hirst E,Patnaik PK,Holder AA

更新日期：2000-07-01 00:00:00

abstract：:Rinderpest virus infection was shown to induce marked suppression of both humoral antibody response and cell-mediated immunity in rabbits. The virus exhibited a suppressive effect on primary antibody response as indicated by a decrease in numbers of plaque-forming cells (immunoglobulin [Ig]M) and hemagglutinating anti...

journal_title：Infection and immunity

authors： Yamanouchi K,Fukuda A,Kobune F,Yoshikawa Y,Chino F

更新日期：1974-02-01 00:00:00