Abstract:
BACKGROUND:Myocarditis complicated by cardiogenic shock remains a complex problem. The use of acute mechanical circulatory support devices for cardiogenic shock is growing. We explored the utility of Impella transvalvular microaxial flow catheters in the setting of myocarditis with cardiogenic shock. METHODS AND RESULTS:We retrospectively analyzed data from 21 sites within the cVAD registry, an ongoing multicenter voluntary registry at sites in North America and Europe that have used Impella in patients with myocarditis. Myocarditis was defined by endomyocardial biopsy (n = 11) or by clinical history without angiographic evidence of coronary disease (n = 23). A total of 34 patients received an Impella 2.5, CP, 5.0, or RP device for cardiogenic shock complicating myocarditis. Baseline characteristics included age 42 ± 17 years, left ventricular ejection fraction (LVEF) 18% ± 10%, cardiac index 1.82 ± 0.46 L·min-1·m-2, pulmonary capillary wedge pressure 25 ± 7 mm Hg, and lactate 27 ± 31 mg/dL. Before Impella placement, 32% (n = 11) of patients required intra-aortic balloon pump. Mean duration of Impella support was 91 ± 74 hours; 21 of 34 patients (62%) survived the index hospitalization and were discharged with an improved mean LVEF of 37.32% ± 20.31% (P = .001); 15 patients recovered with successful support, 5 patients were transferred to another hospital on initial Impella support, 1 patient underwent orthotopic heart transplantation. Ten patients required transition to another mechanical circulatory support device. CONCLUSIONS:This is the largest analysis of Impella-supported myocarditis cases to date. The use of Impella appears to be safe and effective in the settings of myocarditis complicated by cardiogenic shock.
journal_name
J Card Failjournal_title
Journal of cardiac failureauthors
Annamalai SK,Esposito ML,Jorde L,Schreiber T,A Hall S,O'Neill WW,Kapur NKdoi
10.1016/j.cardfail.2018.09.007subject
Has Abstractpub_date
2018-10-01 00:00:00pages
706-710issue
10eissn
1071-9164issn
1532-8414pii
S1071-9164(18)31000-5journal_volume
24pub_type
杂志文章,多中心研究abstract:BACKGROUND:The effect of hospital quality of care on hospital readmission for patients with congestive heart failure (CHF) has not been widely studied. METHODS AND RESULTS:We examined the effects of clinical factors, hospital quality of care, and cardiologist involvement on 3-month readmission rates in patients with C...
journal_title:Journal of cardiac failure
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更新日期:2001-12-01 00:00:00
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
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更新日期:1997-12-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,随机对照试验
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更新日期:2014-05-01 00:00:00
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 更正并重新发布的文章,杂志文章
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更新日期:2013-12-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,评审
doi:10.1016/j.cardfail.2006.12.006
更新日期:2007-05-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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更新日期:2009-02-01 00:00:00
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更新日期:2009-12-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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更新日期:2013-04-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
doi:10.1016/j.cardfail.2020.05.008
更新日期:2020-06-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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更新日期:2009-11-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
doi:10.1016/j.cardfail.2014.08.003
更新日期:2014-11-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of cardiac failure
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pub_type: 杂志文章,评审
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更新日期:1997-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-07-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
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