Extracellular vesicles: translational challenges and opportunities.

Abstract:

:Extracellular vesicles (EVs) are a heterogeneous group of small lipid-enclosed structures with myriad roles in physiology and disease. The recent surge of interest in EVs has led to greater understanding of their biology and appreciation of how they might be utilised as diagnostic and therapeutic tools. There remain, however, a number of challenges that must be overcome before EVs may be used routinely in the clinic. In this review we will discuss the translational potential of EVs and the current technologies available to isolate, purify and analyse EVs and their contents.

journal_name

Biochem Soc Trans

authors

Clemmens H,Lambert DW

doi

10.1042/BST20180112

subject

Has Abstract

pub_date

2018-10-19 00:00:00

pages

1073-1082

issue

5

eissn

0300-5127

issn

1470-8752

pii

BST20180112

journal_volume

46

pub_type

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