Ginseng oligopeptides protect against irradiation-induced immune dysfunction and intestinal injury.

abstract：:PCR-mediated chromosome splitting (PCS) was developed in the yeast Saccharomyces cerevisiae. It is based on homologous recombination and enables division of a chromosome at any point to form two derived and functional chromosomes. However, because of low homologous recombination activity, PCS is limited to a single si...

journal_title：Scientific reports

authors： Sasano Y,Nagasawa K,Kaboli S,Sugiyama M,Harashima S

更新日期：2016-08-17 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is characterized by failure of ovulation and is associated with obesity and chronic inflammation. Recent evidence suggests that anomalous activation of ovarian macrophages and numerical and functional deficits in the Th17 (CD4+IL17A+) and the CD4+CD25+CD127low Tregs plays crucial role ...

journal_title：Scientific reports

authors： Albaghdadi AJH,Feeley CA,Kan FWK

更新日期：2019-04-25 00:00:00

abstract：:Long-term potentiation (LTP) is the persistent increase in the strength of the synapses. However, the neural networks would become saturated if there is only synaptic strenghthening. Synaptic weakening could be facilitated by active processes like long-term depression (LTD). Molecular mechanisms that facilitate the we...

journal_title：Scientific reports

authors： Navakkode S,Chew KCM,Tay SJN,Lin Q,Behnisch T,Soong TW

更新日期：2017-11-14 00:00:00

abstract：:Fluorescence lifetime imaging microscopy (FLIM) is a key technology that provides direct insight into cell metabolism, cell dynamics and protein activity. However, determining the lifetimes of different fluorescent proteins requires the detection of a relatively large number of photons, hence slowing down total acquis...

journal_title：Scientific reports

authors： Zickus V,Wu ML,Morimoto K,Kapitany V,Fatima A,Turpin A,Insall R,Whitelaw J,Machesky L,Bruschini C,Faccio D,Charbon E

更新日期：2020-12-02 00:00:00

abstract：:Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction. We recently developed an innovative experimental model of indivi...

journal_title：Scientific reports

authors： Laricchiuta D,Saba L,De Bartolo P,Caioli S,Zona C,Petrosini L

更新日期：2016-02-15 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. We prospectively evaluated endothelial function by assessing flow-mediated dilatation (FMD) of the brachial artery in patients with biopsy-proven NAFLD. This prospective study included 139 patients (50 healthy controls, 47 patients wi...

journal_title：Scientific reports

authors： Al-Hamoudi W,Alsadoon A,Hassanian M,Alkhalidi H,Abdo A,Nour M,Halwani R,Sanai F,Alsharaabi A,Alswat K,Hersi A,Albenmousa A,Alsaif F

更新日期：2020-06-01 00:00:00

abstract：:The band-edge structure and band gap are key parameters for a functional chalcogenide semiconductor to its applications in optoelectronics, nanoelectronics, and photonics devices. Here, we firstly demonstrate the complete study of experimental band-edge structure and excitonic transitions of monoclinic digallium trisu...

journal_title：Scientific reports

authors： Ho CH,Chen HH

更新日期：2014-08-21 00:00:00

abstract：:The present study investigated when emotion modulates working memory from the perspective of neural activation. Using fMRI, we measured brain activity during the encoding and retrieval phases of a reading span test (RST) that used emotional contexts. The emotional RST required participants to read sentences that elici...

journal_title：Scientific reports

authors： Osaka M,Yaoi K,Minamoto T,Osaka N

更新日期：2013-01-01 00:00:00

abstract：:This paper evaluated a practical approach to the fabrication of arrays of non-spherical nanoparticles by colloidal etching without a mask involving exposure to a low energy ion beam. A spherical nanoparticle array was transferred using a soft nanolithography technique, which is a simple and effective pattern transfer ...

journal_title：Scientific reports

authors： Heo KC,Gwag JS

更新日期：2015-02-17 00:00:00

abstract：:A strain glass state was found to be located between B2-B19' (cubic to monoclinic) phase transition and B2-R (cubic to rhombohedral) phase transition in Ti49Ni51 alloys after aging process. After a short time aging, strong strain glass transition was observed, because the size of the precipitates is small, which means...

journal_title：Scientific reports

authors： Zhou Z,Cui J,Ren X

更新日期：2015-08-26 00:00:00

abstract：:Using second-generation sequencing (SGS) RNA-Seq strategies, extensive alterative splicing prediction is impractical and high variability of isoforms expression quantification is inevitable in organisms without true reference dataset. we report the development of a novel analysis method, termed hybrid sequencing and m...

journal_title：Scientific reports

authors： Ning G,Cheng X,Luo P,Liang F,Wang Z,Yu G,Li X,Wang D,Bao M

更新日期：2017-03-08 00:00:00

abstract：:Inter-digital capacitors (IDCs) with aerosol-deposition (AD) high-k dielectric layer were compared via simulation and measurements of bare IDCs and AD IDCs at room temperature and subjected to a post-annealing process for realizing capacitive super-sensing applications. IDCs with thin AD films can provide higher capac...

journal_title：Scientific reports

authors： Kim ES,Liang JG,Wang C,Cho MY,Oh JM,Kim NY

更新日期：2019-01-24 00:00:00

abstract：:In recent years artificial neural networks achieved performance close to or better than humans in several domains: tasks that were previously human prerogatives, such as language processing, have witnessed remarkable improvements in state of the art models. One advantage of this technological boost is to facilitate co...

journal_title：Scientific reports

authors： Alamia A,Gauducheau V,Paisios D,VanRullen R

更新日期：2020-12-17 00:00:00

abstract：:Myelination is critical for transduction of neuronal signals, neuron survival and normal function of the nervous system. Myelin disorders account for many debilitating neurological diseases such as multiple sclerosis and leukodystrophies. The lack of experimental models and tools to observe and manipulate this process...

journal_title：Scientific reports

authors： Espinosa-Hoyos D,Jagielska A,Homan KA,Du H,Busbee T,Anderson DG,Fang NX,Lewis JA,Van Vliet KJ

更新日期：2018-01-11 00:00:00

abstract：:The three-dimensional construction of arrays of functional molecules on an electrode surface, such as organic semiconductors and redox-active molecules, is a considerable challenge in the fabrication of sophisticated junctions for molecular devices. In particular, well-defined organic layers with precise molecular gra...

journal_title：Scientific reports

authors： Kawauchi T,Oguchi Y,Nagai K,Iyoda T

更新日期：2015-06-09 00:00:00

abstract：:Improving the affinity of protein-protein interactions is a challenging problem that is particularly important in the development of antibodies for diagnostic and clinical use. Here, we used structure-based computational methods to optimize the binding affinity of VHNAC1, a single-domain intracellular antibody (intrab...

journal_title：Scientific reports

authors： Mahajan SP,Meksiriporn B,Waraho-Zhmayev D,Weyant KB,Kocer I,Butler DC,Messer A,Escobedo FA,DeLisa MP

更新日期：2018-12-04 00:00:00

abstract：:Intractable diseases such as cancer are associated with breakdown in multiple individual functions, which conspire to create unhealthy phenotype-combinations. An important challenge is to decipher how these functions are coordinated in health and disease. We approach this by drawing on dynamical systems theory. We pos...

journal_title：Scientific reports

authors： Deritei D,Aird WC,Ercsey-Ravasz M,Regan ER

更新日期：2016-03-16 00:00:00

abstract：:Diabetes is caused by the loss or dysfunction of insulin-secreting β-cells in the pancreas. β-cells reduce their mass and lose insulin-producing ability in vitro, likely due to insufficient cell-cell and cell-extracellular matrix (ECM) interactions as β-cells lose their native microenvironment. Herein, we built an ex-...

journal_title：Scientific reports

authors： Li W,Lee S,Ma M,Kim SM,Guye P,Pancoast JR,Anderson DG,Weiss R,Lee RT,Hammond PT

更新日期：2013-10-04 00:00:00

abstract：:Negative hemodynamic response has been widely reported in blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging studies, however its origin is still controversial. Optical intrinsic signal (OIS) imaging can be used to study brain activity by simultaneously recording hemodynamic signals at diff...

journal_title：Scientific reports

authors： Ma Z,Cao P,Sun P,Zhao L,Li L,Tong S,Lu Y,Yan Y,Chen Y,Chai X

更新日期：2016-02-10 00:00:00

abstract：:Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals. The microbiome has circadian rhythmicity and helps the host circadian clock function. We investigated the ef...

journal_title：Scientific reports

authors： Tahara Y,Yamazaki M,Sukigara H,Motohashi H,Sasaki H,Miyakawa H,Haraguchi A,Ikeda Y,Fukuda S,Shibata S

更新日期：2018-01-23 00:00:00

abstract：:The Pannexin 1 (Panx1) ion and metabolite channel is expressed in a wide variety of cells where it regulates a number of cell behaviours including proliferation and differentiation. Panx1 is expressed on the cell surface as well as intracellular membranes. Previous work suggests that a region within the proximal Panx1...

journal_title：Scientific reports

authors： Epp AL,Ebert SN,Sanchez-Arias JC,Wicki-Stordeur LE,Boyce AKJ,Swayne LA

更新日期：2019-07-05 00:00:00

abstract：:To examine the influence on postoperative endothelial cell density (ECD) caused by preoperative temperature change from 4 °C to room temperature in donor corneas for Descemet stripping automated endothelial keratoplasty (DSAEK). This retrospective, case-controlled comparison of 100 eyes that underwent DSAEK using impo...

journal_title：Scientific reports

authors： Kakisu K,Yamaguchi T,Shimazaki J

更新日期：2020-01-20 00:00:00

abstract：:Vermetids form reefs in sub-tropical and warm-temperate waters that protect coasts from erosion, regulate sediment transport and accumulation, serve as carbon sinks and provide habitat for other species. The gastropods that form these reefs brood encapsulated larvae; they are threatened by rapid environmental changes ...

journal_title：Scientific reports

authors： Milazzo M,Rodolfo-Metalpa R,Chan VB,Fine M,Alessi C,Thiyagarajan V,Hall-Spencer JM,Chemello R

更新日期：2014-02-28 00:00:00

abstract：:Flubendiamide (FD), the first commercial phthalic acid diamide that targets insect ryanodine receptor (RyRs), has played an important role in pest management. With its extensive worldwide application, a rapid and convenient method to detect its existence in the environment is necessary. In this study, an indirect comp...

journal_title：Scientific reports

authors： Li Q,Cui Y,Liao M,Feng T,Tan G,Wang B,Liu S

更新日期：2019-02-14 00:00:00

abstract：:In a previous study, we demonstrated that topical D-beta-hydroxybutyrate ameliorates corneal epithelial erosion and superficial punctate keratopathy in a rat model of dry eye disease. In the current investigation, we performed a prospective, randomized, multicentre, double-blind, placebo-controlled study to assess the...

journal_title：Scientific reports

authors： Kawakita T,Uchino M,Fukagawa K,Yoshino K,Shimazaki S,Toda I,Tanaka M,Arai H,Sakatani K,Hata S,Okano T,Tsubota K

更新日期：2016-02-11 00:00:00

abstract：:The use of impedance-based label free cell analysis is increasingly popular and has many different applications. Here, we report that a real-time cell analyzer (RTCA) can be used to study the stimulation of Natural Killer (NK) cells. Engagement of NK cells via plate-bound antibodies directed against different activati...

journal_title：Scientific reports

authors： Fasbender F,Watzl C

更新日期：2018-03-21 00:00:00

abstract：:Infection after renal transplantation remains a major cause of morbidity and death, especially infection from the extensively drug-resistant bacteria, A. baumannii. A total of fourteen A. baumannii isolates were isolated from the donors' preserved fluid from DCD (donation after cardiac death) renal transplantation and...

journal_title：Scientific reports

authors： Jiang H,Cao L,Qu L,Qu T,Liu G,Wang R,Li B,Wang Y,Ying C,Chen M,Lu Y,Feng S,Xiao Y,Wang J,Wu J,Chen J

更新日期：2017-05-16 00:00:00

abstract：:The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the fina...

journal_title：Scientific reports

authors： Yu G,Li L,Liu X,Liu G,Deng Z,Zabriskie MT,Jiang M,He X

更新日期：2015-12-01 00:00:00

abstract：:In dentistry, the wet-bonding approach relies on water to maintain demineralized collagen expanded for proper resin infiltration; nevertheless, hydrolytic instability of the resin-dentin interface is inevitable with current bonding techniques. Considering dimethyl sulfoxide's (DMSO) ability to "biomodify" collagen and...

journal_title：Scientific reports

authors： Stape THS,Seseogullari-Dirihan R,Tjäderhane L,Abuna G,Martins LRM,Tezvergil-Mutluay A

更新日期：2018-11-15 00:00:00

abstract：:This paper proposes new ways to assess handwriting, a critical skill in any child's school journey. Traditionally, a pen and paper test called the BHK test (Concise Evaluation Scale for Children's Handwriting) is used to assess children's handwriting in French-speaking countries. Any child with a BHK score above a cer...

journal_title：Scientific reports

authors： Asselborn T,Chapatte M,Dillenbourg P

更新日期：2020-02-21 00:00:00