Abstract:
BACKGROUND:The aim of this study was to evaluate the degradation of tryptophan (Trp), neopterin production and antioxidant capacity in patients with benign and malignant thyroid disease. METHODS:For this reason, the levels of tryptophan, kynurenine (Kyn) and neopterin, and superoxide dismutase (SOD) and catalase (CAT) enzyme activities in 67 thyroid patients were evaluated in our study and the results were compared with 30 healthy controls. RESULTS:Tryptophan and kynurenine levels in thyroid patients decreased compared to the control group. Patients with thyroid disease had lower CAT activity than the control group. The neopterin and tryptophan levels in malignant and benign patients were also significantly different. CONCLUSION:The results of the present study suggest that thyroid disorders may lead to changes in tryptophan degradation, neopterin production and CAT enzyme activities.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Ünüvar S,Girgin G,Şahin TT,Kılıçarslan B,Taneri F,Yüksel O,Baydar Tsubject
Has Abstractpub_date
2018-09-01 00:00:00pages
399-405issue
9eissn
1029-2977issn
1735-3947pii
S1029-2977-21(09)399-0journal_volume
21pub_type
杂志文章abstract::Car accidents and gun-shot injuries are the most common causes of spinal cord injury. Five percent of those patients who have a complete spinal cord injury will experience improvement, to some extent. The lack of specific data in the literature regarding the outcome of earthquake related spinal cord injury justified u...
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