Abstract:
:We investigated the association between serum uric acid (SUA) and brachial ankle pulse wave velocity (baPWV) in an apparently healthy population. We performed a cross-sectional study on middle-aged Koreans who completed a yearly health-screening program between January and December 2014. Subjects with coronary artery disease, diabetes, or hypertension were excluded. Linear regression analyses were used to study the relationship between SUA and baPWV. Multiple adjustments were made for variables based on clinical or statistical significance. Of 66,917 study participants (38,170 men and 28,747 women), the mean age was 39.4 ± 6.7 years and the average SUA level was 5.23 ± 1.4 mg/dL. SUA values were higher in men than in women (6.1 ± 1.2 mg/dL vs. 4.1 ± 0.8 mg/dL). SUA was linearly associated with baPWV in women and in men (P < .001, respectively). Multiple regression analyses remained significant for women with a positive association with baPWV across SUA quintiles in a dose-response manner (P < .001) while no longer for men with a J-shaped association between SUA quintiles and baPWV. When SUA modeled continuously, baPWV rose by 12.413 cm/s in women (P < .001) and by 6.588 cm/s in men (P < .001) for each 1 mg/dL increase of SUA. In a low-risk, middle-aged, large Korean population, higher SUA levels could have an unfavorable impact on arterial stiffness as measured by baPWV, and this association was stronger in women than in men.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Hwang J,Hwang JH,Chung SM,Kwon MJ,Ahn JKdoi
10.1097/MD.0000000000012086subject
Has Abstractpub_date
2018-09-01 00:00:00pages
e12086issue
36eissn
0025-7974issn
1536-5964pii
00005792-201809070-00032journal_volume
97pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Pilocytic astrocytoma (PA) is the most common pediatric central nervous system glial tumor. Adult occurrence is rare, especially in elderly adults. How to manage the pilocytic astrocytoma with spontaneous intratumoral hemorrhage in the elderly is still unfamiliar with clinician. PATIENT CONCERNS:Reports of t...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000011329
更新日期:2018-08-01 00:00:00
abstract::To explore the relationship between risk prediction of diabetes mellitus (DM) and different physical fitness parameters in municipal in-service personnel in Guangxi.This was a cross-sectional study conducted in China from July 2015 to December 2016. We enrolled in-service adults (20-65 year of age) from public institu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015842
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:To evaluate if splenectomy results in severely impaired immune responses against primary cytomegalovirus (CMV) infection compared to the general immunocompetent population. METHODS:We performed a systemic literature review to study CMV infections in splenectomized individuals, a special population group pre...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000017698
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) inhibitors are immune therapies that have shown great promise in the treatment of multiple cancers. However, immune-related adverse events of PD-1 and PD-L1 inhibitors may limit their use in non-small cell lung cancer (NSCLC). Given the rising n...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021613
更新日期:2020-08-07 00:00:00
abstract:ABSTRACT:Some evidences suggest the involvement of the central nervous system in patients infected with SARS-CoV-2. We aim to analyze possible associations between coronavirus disease 2019 (COVID-19) pandemic and spontaneous subarachnoid hemorrhage (SAH), in a comprehensive neurological center.We conducted a retrospect...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023862
更新日期:2020-12-18 00:00:00
abstract:INTRODUCTION:Persistent Müllerian duct syndrome (PMDS) is a rare disease occurring in men with an otherwise completely normal phenotype, in which female internal sex organs are present, including a uterus, fallopian tubes, cervix, and vagina. We report a case of bilateral recurrent inguinal hernia due to PMDS treated b...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019079
更新日期:2020-02-01 00:00:00
abstract:RATIONALE:A dural arteriovenous fistula (DAVF) refers to an abnormal direct connection between an intracranial artery and a dural venous sinus. A DAVF presenting with parkinsonism is rare, and is therefore easily misdiagnosed. Therefore, early consideration of DAVF in the differential diagnosis of reversible parkinsoni...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009005
更新日期:2017-12-01 00:00:00
abstract:RATIONALE:Glomus tumors (GTs) are rare soft tissue neoplasms. Several treatment options have been reported for tracheal GTs including thoracotomy, bronchoscopic electrocautery, Nd: YAG laser, and cryotherapy. However, few studies have evaluated the ideal treatment for tracheal GTs. PATIENT CONCERNS:A 30-year old man w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010374
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:DNA methylation is the earliest and most studied epigenetic modification in cancer. The literature reported that the abnormal methylation level of multiple genes was associated with poor prognosis in ovarian cancer. However, due to a small sample size, the results reported in the literature vary widely. In th...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000014588
更新日期:2019-02-01 00:00:00
abstract::Ankylosing spondylitis (AS) is a chronic inflammatory disease involing spine and enthesis. The primary aim of this study is to investigate the autonomic nervous system (ANS) function and the association between ANS and the functional status or disease activity in AS.The study included 42 AS patients, all fulfilling th...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003749
更新日期:2016-05-01 00:00:00
abstract::Alanine transaminase (ALT) abnormalities are common in chronic hepatitis B (CHB) carriers during postpartum period. Disturbances in cytokines are considered to be associated with hepatitis Flares. There are limited data on cytokines changes in HBeAg positive patients with ALT abnormalities.This is an observational stu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017969
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:To date, the anti-gravity treadmill (AlterG), as a representative method of Lower body positive pressure (LBPP) treadmills, has been rarely reported for knee osteoarthritis (KOA) rehabilitation. The purpose of this case study was to setup the clinical protocol example for AlterG intervention on KOA and eva...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015386
更新日期:2019-05-01 00:00:00
abstract:RATIONALE:Persistent primitive hypoglossal artery (PPHA) is often associated with intracranial anomalies such as aneurysms. Surgical treatment of aneurysms on the PPHA is challenging due to that the posterior circulation depends solely on PPHA. PATIENT CONCERNS:A case of an 83-year-old woman with a large aneurysm on P...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017151
更新日期:2019-09-01 00:00:00
abstract::Numerous studies document significant improvement in motor symptoms in patients with Parkinson's disease (PD) after deep brain stimulation of the subthalamic nucleus (STN-DBS). However, little is known about the initial effects of STN-DBS on nonmotor domains.Our objective was to elucidate the initial effects of STN-DB...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009750
更新日期:2018-02-01 00:00:00
abstract:RATIONALE:Immune checkpoint inhibitors have led to the development of new approaches for cancer treatment with positive outcomes. However, checkpoint blockade is associated with a unique spectrum of immune-related adverse events (irAEs), which may cause irreversible neurological deficits and even death. PATIENT CONCER...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000009262
更新日期:2017-12-01 00:00:00
abstract:RATIONALE:Primary leiomyosarcoma (LMS) of the fallopian tube is extremely uncommon. To the best of our knowledge, so far only 21 cases of primary fallopian tube LMS have been reported in English-language literature. No new case has been reported in the past 7 years. PATIENT CONCERNS:A 44-year-old premenopausal patient...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000010536
更新日期:2018-04-01 00:00:00
abstract:RATIONALE:Thyroglobulin (Tg) is an accurate indicator of clinical outcome after total thyroidectomy in patients with differentiated thyroid carcinoma. Usually, Tg levels agree with whole body scan. However, in some patient, discordant results were found, often because of Tg immunoassay interference. Several reports ind...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014178
更新日期:2019-02-01 00:00:00
abstract::The risk calculator of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) has been shown to be useful in predicting postoperative complications. In this study, we aimed to evaluate the predictive value of the ACS-NSQIP calculator in geriatric patients undergoing lumbar surgery.A...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008416
更新日期:2017-10-01 00:00:00
abstract::Recent studies have revealed a link between estradiol (E2) and glucose homeostasis. We aimed to assess the association between cord blood hormone levels and the risk of gestational diabetes mellitus (GDM).A total of 204 pregnant women with GDM and 204 pregnant women without GDM (control) were included in the study. Ma...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006962
更新日期:2017-05-01 00:00:00
abstract::Endotracheal tube (ETT) positioning using the cuff ballottement test, which confirms that the inflated cuff is positioned at the suprasternal notch with squeezing or inflating a pilot balloon, has been reported to be a simple and reliable method of preventing endobronchial intubation. However, in patients with a short...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006155
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Left ventricular (LV) remodeling after myocardial injury, volume or pressure overload is characterized by a change in LV shape from an ellipse to more of a sphere. The usefulness of 3-dimensional (3D) sphericity index (SpI) for accurate evaluation of LV remodeling remains uncertain despite extensive research...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000007968
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:The prevalence of Brugada ECG pattern (BrEP) is different in different regions, and its mean prevalence over the world is unknown. The risk of people with BrEP for death remains unknown. We performed a meta-analysis to determine the prevalence of BrEP and risk ratio (RR) for death. METHODS:Relevant studies ...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000005643
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Osteopathic medicine is an emerging and complementary method used in neonatology. METHODS:Outcomes were the mean difference in length of stay (LOS) and costs between osteopathy and alternative treatment group. A comprehensive literature search of (quasi)- randomized controlled trials (RCTs), was conducted f...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000006408
更新日期:2017-03-01 00:00:00
abstract::In the past 20 years, posturography has been widely used in the medical field. This observational study aimed to report the values derived from posturography of a wide set of healthy subjects from various European countries using a plantar pressure platform and a standardized method of measurement.A random cluster sam...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013835
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:This research aims to evaluate the efficacy and safety of synbiotics for treating chronic kidney disease. METHODS:Related articles written in English were sourced from EMBASE, PubMed, Cochrane Library, and China National Knowledge Infrastructure. These articles were used in the evaluation of the effect of s...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022993
更新日期:2020-12-04 00:00:00
abstract::Exosomes are nanometer-sized vesicles with intercellular communication functions, and their encapsulated proteins may participate in the pathological process of neurodegenerative disorders. The aim of this study was to identify the protein changes of serum exosomes in Parkinson disease (PD) patients with different dis...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017478
更新日期:2019-10-01 00:00:00
abstract::This study is to establish the nomogram model and provide clinical therapy decision-making for extensive-stage small-cell lung cancer (ES-SCLC) patients with different metastatic sites using the Surveillance, Epidemiology, and End Results (SEER) Program.A total of 10,025 patients of ES-SCLC with metastasis from Januar...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021798
更新日期:2020-08-14 00:00:00
abstract:BACKGROUND:Recent studies have shown the efficacy for using spironolactone to treat heart failure with reduced ejection fraction (HFrEF), but the efficacy of spironolactone for heart failure with mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) is unclear. This meta-analys...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000014967
更新日期:2019-03-01 00:00:00
abstract::The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are not fully evaluated for the diagnosis of musculoskeletal tumors, especially spine tumors. The objective of our study was to assess the feasibility of NLR and PLR as indicators for pretreatment diagnosis of spine tumors.Patients who...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014902
更新日期:2019-04-01 00:00:00
abstract:RATIONALE:Carcinosarcoma, an extremely rare pancreatic primary tumor, is characterized by coexistence of both carcinomatous and sarcomatous components. Due to its rarity, the clinical manifestation and imaging features have not been recognized. An accurate diagnostic method has not been available and a widely accepted ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000006961
更新日期:2017-06-01 00:00:00