Analysis of the Atlantic salmon genome reveals a cluster of Mx genes that respond more strongly to IFN gamma than to type I IFN.

abstract：:We report on the cloning and characterization of Trypanosoma carassii 70 KDa heat shock protein (hsp70). T. carassii hsp70 was secreted/excreted into culture medium in vitro and was recognized by sera from infected fish. Recombinant hsp70 (rhsp70) activated goldfish macrophages and stimulated the production of pro-inf...

journal_title：Developmental and comparative immunology

authors： Oladiran A,Belosevic M

更新日期：2009-10-01 00:00:00

abstract：:The respiratory glycoprotein, hemocyanin (HMC) has multiple immune-related functions, including antiviral activity. In this study, in silico methods were used to predict seven miRNAs targeting Litopenaeus vannamei HMC (LvHMC), out of which miR-589-5p was selected for further investigation because of its role in immune...

journal_title：Developmental and comparative immunology

authors： Bao S,Zheng Z,Aweya JJ,Yao D,Li S,Sun C,Hong Y,Zhang Y

更新日期：2020-06-01 00:00:00

abstract：:ADP-ribosylation factors (Arfs) are small GTP-binding proteins that have an essential function in intracellular trafficking and organelle structure. To date, little information is available on the Arfs in the economically important giant freshwater prawn Macrobrachium rosenbergii and their relationship to viral infect...

journal_title：Developmental and comparative immunology

authors： Ding ZF,Ren J,Tan JM,Wang Z,Yin SW,Huang Y,Huang X,Wang W,Lan JF,Ren Q

更新日期：2015-01-01 00:00:00

abstract：:We describe a novel antigen recognized by mAb 2E3 selectively expressed in the periphery by a subset of porcine CD4+ T cells. Both, CD4+CD8alpha- and CD4+CD8alphalow T cell subpopulations express this antigen. CD4+2E3+ T cells show phenotypical and functional characteristics of nai;ve cells. The majority of them are C...

journal_title：Developmental and comparative immunology

authors： Revilla C,Rodríguez-Carreño MP,Alvarez B,Chamorro S,Alonso LM,Ezquerra A,Alonso F,Domínguez J

更新日期：2004-03-01 00:00:00

abstract：:This study characterizes immunoglobulin light chain (IgL) expression and variable family usage in rainbow trout. IgL transcripts were generated by 5' RACE from both immune and TNP-KLH immunized fish. Phylogenetic analysis revealed that the IgL variable regions clustered into seven different families: three kappa famil...

journal_title：Developmental and comparative immunology

authors： Rego K,Bengtén E,Wilson M,Hansen JD,Bromage ES

更新日期：2020-03-01 00:00:00

abstract：:In all vertebrates studied to date, the expression of MHC class II genes is known to be restricted to a limited number of tissues and cell types. In order to have a better understanding of the function of the equivalent genes in teleost fish, the distribution of MHC class II beta transcripts (Cyca-DAB) in the common c...

journal_title：Developmental and comparative immunology

authors： Rodrigues PN,Hermsen TT,Rombout JH,Egberts E,Stet RJ

更新日期：1995-11-01 00:00:00

abstract：:IFN-λ (IFNL), i.e. type III IFN genes were found in a conserved gene locus in tetrapod vertebrates. But, a unique locus containing IFNL was found in avian. In turtle and crocodile, IFNL genes were distributed in these two separate loci. As revealed in phylogenetic trees, IFN-λs in these two different loci and other am...

journal_title：Developmental and comparative immunology

authors： Chen SN,Zhang XW,Li L,Ruan BY,Huang B,Huang WS,Zou PF,Fu JP,Zhao LJ,Li N,Nie P

更新日期：2016-08-01 00:00:00

abstract：:The Ikaros gene encodes a family of transcription factors which plays a crucial role in hematopoiesis. To improve our knowledge about the immune system of Pleurodeles waltl, we sequenced the cDNA coding for the Ik-1 isoform of that salamander and analyzed its tissue expression by semi-quantitative RT-PCR. Ikaros trans...

journal_title：Developmental and comparative immunology

authors： Boudarra N,Frippiat C,Dournon C,Frippiat JP

更新日期：2002-09-01 00:00:00

abstract：:The snail Biomphalaria glabrata kills the blood fluke Schistosoma mansoni by a mechanism involving production of hydrogen peroxide, the enzymatic product of cytosolic Cu/Zn superoxide dismutase (SOD1). This enzyme exhibits higher activity in blood cells (hemocytes) from a predominantly resistant strain of B. glabrata ...

journal_title：Developmental and comparative immunology

authors： Bender RC,Goodall CP,Blouin MS,Bayne CJ

更新日期：2007-01-01 00:00:00

abstract：:Gut-associated lymphoid tissue (GALT) development requires interaction with the intestinal microbiota. Because murine secondary lymphoid tissue development is driven by positive feedback interactions between B cells and stromal cells, we used in situ hybridization to determine whether intestinal commensals influence s...

journal_title：Developmental and comparative immunology

authors： Hanson NB,Lanning DK

更新日期：2008-01-01 00:00:00

abstract：:The ruminant gut-associated lymphoid tissues are broadly classified into ileal and jejunal Peyer's patches (PP). We isolated single lymphatic follicles from ileal and jejunal PP and examined mRNA expression of 13 cytokines using RT-PCR. Four patterns of differential expression were identified. In Pattern 1, the cytoki...

journal_title：Developmental and comparative immunology

authors： Yasuda M,Nasu T,Murakami T

更新日期：2009-04-01 00:00:00

abstract：:PTEN, a tumor suppressor gene, suppresses cell survival, growth, apoptosis, cell migration and DNA damage repair by inhibiting the PI3K/AKT signaling pathway. In this study, the full-length Litopenaeus vannamei PTEN (LvPTEN) cDNA was obtained, containing a 5'UTR of 59bp, an ORF of 1269bp and a 3'UTR of 146bp besides t...

journal_title：Developmental and comparative immunology

authors： Xie CY,Kong JR,Zhao CS,Xiao YC,Peng T,Liu Y,Wang WN

更新日期：2016-06-01 00:00:00

abstract：:Toll-like receptors (TLRs)are pattern recognition receptors (PRRs) that are important in invertebrate innate immunity for the recognition and elimination of pathogens. Although they were reported in many fishes, Toll-like receptors subfamily contain a large number of members with different functions that need to resea...

journal_title：Developmental and comparative immunology

authors： Wu M,Zhu KC,Guo HY,Guo L,Liu B,Jiang SG,Zhang DC

更新日期：2021-04-01 00:00:00

abstract：:Fusion experiments with three colonies (AC-BC-BD) by Tanaka and Watanabe indicated that the mixture of blood from two nonfusible colonies induced a "nonfusion" reaction (NFR)-like responses. Thus, artificial mixture of the blood from two nonfusible colonies is expected to result in NFR-like reactions. The present stud...

journal_title：Developmental and comparative immunology

authors： Taneda Y,Watanabe H

更新日期：1982-04-01 00:00:00

abstract：:Brief pretreatment of cold shock at 13 °C for 3 min proved to be an inducer of heat shock protein 70 (HSP70) and improved stress tolerance as a molecular chaperone. With the improvement of air exposure tolerance, HSP70 in shrimp hemocytes was upregulated in mRNA and protein levels after cold shock. Both HSP70 RNA inte...

journal_title：Developmental and comparative immunology

authors： Guan W,Wei X,Nong W,Shao Y,Mao L

更新日期：2021-01-01 00:00:00

abstract：:The IMD pathway signaling plays a pivotal role in the Drosophila defense against bacteria. During the last two decades, significant progress has been made in identifying the components and deciphering the molecular mechanisms underlying this pathway, including the means of bacterial sensing and signal transduction. Wh...

journal_title：Developmental and comparative immunology

authors： Kleino A,Silverman N

更新日期：2014-01-01 00:00:00

abstract：:Thymic non-lymphoid cells have been shown to influence the differentiation of T-lymphocytes. Large numbers of non-lymphoid cells are concentrated in the thymic medullary zone. A morphometric analysis of these cells in the medulla identified little change in their absolute number and volume density during thymic develo...

journal_title：Developmental and comparative immunology

authors： Higley HR,O'Morchoe CC

更新日期：1984-07-01 00:00:00

abstract：:Cathepsins belongs to the cysteine protease family, which are activated by an acidic environment. They play essential biological roles in the innate immunity and development of animals. Here, we identified a 62 kDa cathepsin L-like protease from the silkworm Bombyx mori. It contained putative conserved domains, includ...

journal_title：Developmental and comparative immunology

authors： Sun YX,Chen C,Xu WJ,Abbas MN,Mu FF,Ding WJ,Zhang HJ,Li J

更新日期：2021-03-01 00:00:00

abstract：:QX is a fatal disease in Sydney rock oysters (Saccostrea glomerata) that results from infection by the protistan parasite, Marteilia sydneyi. Since 1997, the New South Wales Fisheries Service has bred S. glomerata for resistance to QX disease. The current study shows that the QX resistance breeding program has selecte...

journal_title：Developmental and comparative immunology

authors： Newton K,Peters R,Raftos D

更新日期：2004-05-17 00:00:00

abstract：:Serious juvenile oyster disease induced by pathogenic Vibrio splendidus has resulted in tremendous economic loss, but the molecular mechanisms underlying this killing mechanism remain unclear. The resistance of adult oyster to V. splendidus or its virulence factors might provide a possible access to cognize the intera...

journal_title：Developmental and comparative immunology

authors： Wang W,Lv X,Liu Z,Song X,Yi Q,Wang L,Song L

更新日期：2020-01-01 00:00:00

abstract：:We investigated the effect of brown ring disease (BRD) development and algal diet on energy reserves and activity of enzymes related to energy metabolism, antioxidant system and immunity in Manila clam, Ruditapes philippinarum. We found that algal diet did not impact the metabolic response of clams exposed to Vibrio t...

journal_title：Developmental and comparative immunology

authors： Richard G,Guérard F,Corporeau C,Lambert C,Paillard C,Pernet F

更新日期：2016-07-01 00:00:00

abstract：:TLR7 subfamily members are important pattern recognition receptors participating in the recognition of pathogen-associated molecular patterns. In this study, we successfully identified 3 members of TLR7 subfamily from the spiny eel Mastacembelus armatus (MaTLR7, MaTLR8 and MaTLR9). The amino acid sequence identities o...

journal_title：Developmental and comparative immunology

authors： Han C,Li Q,Liu J,Hao Z,Huang J,Zhang Y

更新日期：2019-06-01 00:00:00

abstract：:White spot syndrome virus (WSSV), the causative agent of white spot disease (WSD), is a serious and aggressive shrimp viral pathogen with a worldwide distribution. At the genome replication stage (12 hpi), WSSV induces a metabolic rerouting known as the invertebrate Warburg effect, which boosts the availability of ene...

journal_title：Developmental and comparative immunology

authors： Hsieh YC,Chen YM,Li CY,Chang YH,Liang SY,Lin SY,Lin CY,Chang SH,Wang YJ,Khoo KH,Aoki T,Wang HC

更新日期：2015-11-01 00:00:00

abstract：:The ingestion of sheep erythrocytes (SRBC) by echinoid phagocytes was greatly increased after treatment of SRBC with sera from mouse, human and fish. The opsonic principle in the sera was heat labile (56 degrees C 1/2 hr). Opsonization with mammalian sera was studied more extensively. It was dependent on pre-sensitiza...

journal_title：Developmental and comparative immunology

authors： Bertheussen K,Seljelid R

更新日期：1982-07-01 00:00:00

abstract：:There is increasing concern about the possible effect of pharmaceutical compounds may have on the fish immune system. Bath exposition of 17α-ethynylestradiol (EE2), a synthetic estrogen used in oral contraceptives, altered the immune response of the gilthead seabream (Sparus aurata L.), a marine hermaphrodite teleost....

journal_title：Developmental and comparative immunology

authors： Rodenas MC,Cabas I,Abellán E,Meseguer J,Mulero V,García-Ayala A

更新日期：2015-12-01 00:00:00

abstract：:The development of mammalian megakaryocytes and platelets is regulated by numerous cytokine signals, primarily through the thrombopoietin (TPO)/c-MPL axis. Although non-mammalian vertebrates are known to possess nucleated thrombocytes functionally equivalent to mammalian platelets, the dynamics of the thrombocyte deve...

journal_title：Developmental and comparative immunology

authors： Katakura F,Sugie Y,Hayashi K,Nishiya K,Miyamae J,Okano M,Nakanishi T,Moritomo T

更新日期：2018-07-01 00:00:00

abstract：:Invertebrates utilise the innate immune system when defending against pathogenic attack. However, except for some effectors as proPhenolOxidase (proPO), the innate immune response is less well understood outside model insect species, and its role in natural host-pathogen systems is generally not well documented. We ha...

journal_title：Developmental and comparative immunology

authors： Labbé P,Little TJ

更新日期：2009-05-01 00:00:00

abstract：:The intestinal immune system in Gallus species must rapidly adapt to the omnivorous onset of an adult diet and to colonization by commensal bacteria. Yet, acquired immune functions in Gallus digestive tract fully develop only towards the end of the first week post-hatch. This raises the question of immune protection i...

journal_title：Developmental and comparative immunology

authors： Bar-Shira E,Friedman A

更新日期：2006-01-01 00:00:00

abstract：:Suppressor of cytokine signaling (SOCS) proteins are crucially involved in the control of inflammatory responses through their impact on various signaling pathways including the JAK/STAT pathway. Although all SOCS protein family members are identified in teleost fish, their functional properties in non-mammalian verte...

journal_title：Developmental and comparative immunology

authors： Skjesol A,Liebe T,Iliev DB,Thomassen EI,Tollersrud LG,Sobhkhez M,Lindenskov Joensen L,Secombes CJ,Jørgensen JB

更新日期：2014-07-01 00:00:00

abstract：:Two isoforms of plasmolipin were initially identified from the black tiger shrimp (Penaeus monodon) EST database and completed using 50 RACE to reveal complete cDNAs of 558 bp (PmPLP1) and 537 bp(PmPLP2) with 87% nucleotide sequence identity. The deduced amino acid sequences contained four-transmembrane domains and sh...

journal_title：Developmental and comparative immunology

authors： Vatanavicharn T,Pongsomboon S,Tassanakajon A

更新日期：2012-10-01 00:00:00