Author Correction: Role of extrinsic mechanical force in the development of the RA-I tactile mechanoreceptor.

abstract：:Metabolomics was applied to a C57BL/6N mouse model of chronic unpredictable mild stress (CMS). Such mice were treated with two antidepressants from different categories: fluoxetine and imipramine. Metabolic profiling of the hippocampus was performed using gas chromatography-mass spectrometry analysis on samples prepar...

journal_title：Scientific reports

authors： Zhao J,Jung YH,Jang CG,Chun KH,Kwon SW,Lee J

更新日期：2015-03-09 00:00:00

abstract：:Subjective refraction is the gold-standard for prescribing refractive correction, but its accuracy is limited by patient's subjective judgment about their clarity of vision. We asked if an involuntary eye movement, optokinetic nystagmus (OKN), could serve as an objective measure of visual-clarity, specifically measuri...

journal_title：Scientific reports

authors： Doustkouhi SM,Turnbull PRK,Dakin SC

更新日期：2020-11-18 00:00:00

abstract：:The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA ...

journal_title：Scientific reports

authors： Dai L,Wang L,Deng L,Liu J,Lei J,Li D,He J

更新日期：2014-07-29 00:00:00

abstract：:Antimicrobial resistance (AMR) is a major public health threat. Plasmids are able to transfer AMR genes among bacterial isolates. Whole genome sequencing (WGS) is a powerful tool to monitor AMR determinants. However, plasmids are difficult to reconstruct from WGS data. This study aimed to improve the characterization,...

journal_title：Scientific reports

authors： Berbers B,Saltykova A,Garcia-Graells C,Philipp P,Arella F,Marchal K,Winand R,Vanneste K,Roosens NHC,De Keersmaecker SCJ

更新日期：2020-03-09 00:00:00

abstract：:Activity-regulated cytoskeleton-associated protein (Arc; also known as Arg3.1) is an immediate early gene product that is transcribed in dendritic spines and, to date, has been best characterized as a positive regulator of AMPAR endocytosis during long-term depression (LTD) through interaction with endocytic proteins....

journal_title：Scientific reports

authors： Goo BMSS,Sanstrum BJ,Holden DZY,Yu Y,James NG

更新日期：2018-10-02 00:00:00

abstract：:Knowledge of bacteria's heat resistance is essential for developing effective thermal treatments. Choosing an appropriate test method is important to accurately determine bacteria's heat resistances. Although being a major factor to influence the thermo-tolerance of bacteria, the heating rate in samples cannot be cont...

journal_title：Scientific reports

authors： Kou XX,Li R,Hou LX,Huang Z,Ling B,Wang SJ

更新日期：2016-07-28 00:00:00

abstract：:The effect of AM fungi spatial distribution on individual plant development may determine the dynamics of the whole plant community. We investigated whether clonal plants display, like for other resources, a foraging or a specialization response, to adapt to the distribution of AM fungi. Two separate experiments were ...

journal_title：Scientific reports

authors： Vannier N,Bittebiere AK,Vandenkoornhuyse P,Mony C

更新日期：2016-11-25 00:00:00

abstract：:Rust fungi are plant pathogens that secrete an arsenal of effector proteins interfering with plant functions and promoting parasitic infection. Effectors are often species-specific, evolve rapidly, and display low sequence similarities with known proteins. How rust fungal effectors function in host cells remains elusi...

journal_title：Scientific reports

authors： de Guillen K,Lorrain C,Tsan P,Barthe P,Petre B,Saveleva N,Rouhier N,Duplessis S,Padilla A,Hecker A

更新日期：2019-12-02 00:00:00

abstract：:Animals achieve camouflage through a variety of mechanisms, of which background matching and disruptive coloration are likely the most common. Although many studies have investigated camouflage mechanisms using artificial stimuli and in lab experiments, less work has addressed camouflage in the wild. Here we examine e...

journal_title：Scientific reports

authors： Stoddard MC,Kupán K,Eyster HN,Rojas-Abreu W,Cruz-López M,Serrano-Meneses MA,Küpper C

更新日期：2016-09-12 00:00:00

abstract：:Developing effective treatment strategies for neurodegenerative diseases require an understanding of the underlying cellular pathways that lead to neuronal vulnerability and progressive degeneration. To date, numerous mutations in 147 distinct genes are identified to be "associated" with, "modifier" or "causative" of ...

journal_title：Scientific reports

authors： Dervishi I,Gozutok O,Murnan K,Gautam M,Heller D,Bigio E,Ozdinler PH

更新日期：2018-10-03 00:00:00

abstract：:Quantum coherence is one of the old but always important concepts in quantum mechanics, and now it has been regarded as a necessary resource for quantum information processing and quantum metrology. However, the question of how to quantify the quantum coherence has just been paid the attention recently (see, e.g., Bau...

journal_title：Scientific reports

authors： Feng XN,Wei LF

更新日期：2017-11-14 00:00:00

abstract：:Cell wall disruption is necessary to maximize lipid extraction yields in conventional species of mass-cultivated microalgae. This study investigated the effect of sonication, solvent choice and number of extractions on the lipid yield, lipid class composition and fatty acid composition of the diatom Porosira glacialis...

journal_title：Scientific reports

authors： Svenning JB,Dalheim L,Vasskog T,Matricon L,Vang B,Olsen RL

更新日期：2020-12-17 00:00:00

abstract：:Practical applications of bacteriophages in medicine and biotechnology induce a great need for technologies of phage purification. None of the popular methods offer solutions for separation of a phage from another similar phage. We used affinity chromatography combined with competitive phage display (i) to purify T4 b...

journal_title：Scientific reports

authors： Ceglarek I,Piotrowicz A,Lecion D,Miernikiewicz P,Owczarek B,Hodyra K,Harhala M,Górski A,Dąbrowska K

更新日期：2013-11-14 00:00:00

abstract：:Synapses are an early pathological target in many neurodegenerative diseases ranging from well-known adult onset conditions such as Alzheimer and Parkinson disease to neurodegenerative conditions of childhood such as spinal muscular atrophy (SMA) and neuronal ceroid lipofuscinosis (NCLs). However, the reasons why syna...

journal_title：Scientific reports

authors： Llavero Hurtado M,Fuller HR,Wong AMS,Eaton SL,Gillingwater TH,Pennetta G,Cooper JD,Wishart TM

更新日期：2017-09-29 00:00:00

abstract：:Electrostatic gates are of paramount importance for the physics of devices based on high-mobility two-dimensional electron gas (2DEG) since they allow depletion of electrons in selected areas. This field-effect gating enables the fabrication of a wide range of devices such as, for example, quantum point contacts (QPC)...

journal_title：Scientific reports

authors： Bennaceur K,Schmidt BA,Gaucher S,Laroche D,Lilly MP,Reno JL,West KW,Pfeiffer LN,Gervais G

更新日期：2015-09-22 00:00:00

abstract：:Erwinia tracheiphila is a bacterial plant pathogen that causes a fatal wilt infection in some cucurbit crop plants. Wilt symptoms are thought to be caused by systemic bacterial colonization through xylem that impedes sap flow. However, the genetic determinants of within-plant movement are unknown for this pathogen spe...

journal_title：Scientific reports

authors： Rocha J,Shapiro LR,Kolter R

更新日期：2020-12-10 00:00:00

abstract：:Metabolic disorders in T2DM generate multiple sources of free radicals and oxidative stress that accelerate nonenzymatic degenerative protein modifications (DPMs) such as protein oxidation, disrupt redox signaling and physiological function, and remain a major risk factor for clinical diabetic vascular complications. ...

journal_title：Scientific reports

authors： Paramasivan S,Adav SS,Ngan SC,Dalan R,Leow MK,Ho HH,Sze SK

更新日期：2020-04-15 00:00:00

abstract：:The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residues 1-100) in a comp...

journal_title：Scientific reports

authors： Chen LY,Huang YC,Huang ST,Hsieh YC,Guan HH,Chen NC,Chuankhayan P,Yoshimura M,Tai MH,Chen CJ

更新日期：2018-01-10 00:00:00

abstract：:In this work, the circular dichroisms (CD) of nanorice heterodimers consisting of two parallel arranged nanorices with the same size but different materials are investigated theoretically. Symmetry-breaking is introduced by using different materials and oblique incidence to achieve strong CD at the vicinity of Fano re...

journal_title：Scientific reports

authors： Hu L,Huang Y,Fang L,Chen G,Wei H,Fang Y

更新日期：2015-11-05 00:00:00

abstract：:Metal pollution in drinking water source has been under scrutiny as it seriously affects human health. This work examined 12 dissolved metals in the surface and overlying water of the Xiangjiang River, an important drinking water source in southern China, and characterized their distribution, identified their possible...

journal_title：Scientific reports

authors： Huang Z,Zheng S,Liu Y,Zhao X,Qiao X,Liu C,Zheng B,Yin D

更新日期：2021-01-08 00:00:00

abstract：:The association between cervical lymph node metastasis (LNM) and ultrasonographic features as well as BRAFV600E mutations in patients with papillary thyroid carcinoma (PTC) remained controversial. This study investigated the association between LNM and ultrasonographic features as well as BRAFV600E mutation in Chinese...

journal_title：Scientific reports

authors： Guo L,Ma YQ,Yao Y,Wu M,Deng ZH,Zhu FW,Luo YK,Tang J

更新日期：2019-01-11 00:00:00

abstract：:Eucalyptus globulus is an aromatic medicinal plant which known for its 1,8-cineole main pharmacological constituent exhibits as natural analgesic agent. Eucalyptus globulus-loaded micellar nanoparticle was developed via spontaneous emulsification technique and further evaluation for its analgesic efficacy study, in vi...

journal_title：Scientific reports

authors： Aziz ZAA,Nasir HM,Ahmad A,Setapar SHM,Ahmad H,Noor MHM,Rafatullah M,Khatoon A,Kausar MA,Ahmad I,Khan S,Al-Shaeri M,Ashraf GM

更新日期：2019-09-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Brilha S,Ong CWM,Weksler B,Romero N,Couraud PO,Friedland JS

更新日期：2018-09-12 00:00:00

abstract：:Rapid changes observed today in mountain glaciers need to be put into a longer-term context to understand global sea-level contributions, regional climate-glacier systems and local landscape evolution. In this study we determined volume changes for 400 mountain glaciers across the Southern Alps, New Zealand for three ...

journal_title：Scientific reports

authors： Carrivick JL,James WHM,Grimes M,Sutherland JL,Lorrey AM

更新日期：2020-08-07 00:00:00

abstract：:In earlier studies, we showed that ATF4 down-regulation affects post-synaptic development and dendritic spine morphology in neurons through increased turnover of the Rho GTPase Cell Division Cycle 42 (Cdc42) protein. Here, we find that ATF4 down-regulation in both hippocampal and cortical neuron cultures reduces prote...

journal_title：Scientific reports

authors： Pasini S,Liu J,Corona C,Peze-Heidsieck E,Shelanski M,Greene LA

更新日期：2016-11-14 00:00:00

abstract：:Non-invasive imaging of arthritis activity in rheumatoid arthritis (RA) patients using macrophage PET holds promise for early diagnosis and therapeutic response monitoring. Previously obtained results with macrophage tracer (R)-[11C]PK11195 were encouraging, but the imaging signal could be further improved by reductio...

journal_title：Scientific reports

authors： Verweij NJF,Yaqub M,Bruijnen STG,Pieplenbosch S,Ter Wee MM,Jansen G,Chen Q,Low PS,Windhorst AD,Lammertsma AA,Hoekstra OS,Voskuyl AE,van der Laken CJ

更新日期：2020-01-23 00:00:00

abstract：:Microfracture of cartilage defects may induce alterations of the subchondral bone in the mid- and long-term, yet very little is known about their onset. Possibly, these changes may be avoided by an enhanced microfracture technique with additional application of bone marrow aspirate. In this study, full-thickness chond...

journal_title：Scientific reports

authors： Gao L,Orth P,Müller-Brandt K,Goebel LK,Cucchiarini M,Madry H

更新日期：2017-03-27 00:00:00

abstract：:Lanzhou lamb rotavirus vaccine (LLR) is an oral live attenuated vaccine first licensed in China in 2000. To date, > 60 million doses of LLR have been distributed to children. However, very little is known about faecal shedding of LLR in children. Therefore, faecal samples (n = 1,184) were collected from 114 children f...

journal_title：Scientific reports

authors： Li JS,Cao B,Gao HC,Li DD,Lin L,Li LL,Liu N,Duan ZJ

更新日期：2018-01-17 00:00:00

abstract：:The exposure of humans to erionite fibres of appropriate morphology and dimension has been unambiguously linked to the occurrence of Malignant Mesothelioma. For this reason, a detailed morpho-structural investigation through Electron Microscopy techniques has been performed on erionite samples collected at two differe...

journal_title：Scientific reports

authors： Matassa R,Familiari G,Relucenti M,Battaglione E,Downing C,Pacella A,Cametti G,Ballirano P

更新日期：2015-11-16 00:00:00

abstract：:Because of ubiquity of thioesters, thioesterases play a critical role in metabolism, membrane biosynthesis, signal transduction, and gene regulation. In many bacteria, YbgC is such an enzyme, whose coding gene mostly resides in the tol-pal cluster. Although all other proteins encoded in the tol-pal cluster are clearly...

journal_title：Scientific reports

authors： Gao T,Meng Q,Gao H

更新日期：2017-06-21 00:00:00