A scoring system to detect fixed airflow limitation in smokers from simple easy-to-use parameters.

abstract：:This article puts forward a technique for extracting the density of trap states (DOST) distribution based on the transient photo-voltage (TPV) measurement result. We prove that when the TPV result is linear, the DOST distribution is exponential type and vice versa. Compared to the approach based on the space charge li...

journal_title：Scientific reports

authors： Lin Z

更新日期：2020-07-30 00:00:00

abstract：:Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of SHP-2 have been foun...

journal_title：Scientific reports

authors： Shim SY,Jeong HJ,Park HJ,Kwon EY,Kim BM,Choi YJ,Choi YH,Cho SJ,Choi JH,Park EA

更新日期：2017-07-20 00:00:00

abstract：:Latent class modeling can be used to combine the results of multiple tests to compare the sensitivity and specificity of those tests in the absence of a gold standard. Seroepidemiology for chlamydia infection may be useful for determining the cumulative risk of infection within a population. Initial studies using the ...

journal_title：Scientific reports

authors： Wiegand RE,Cooley G,Goodhew B,Banniettis N,Kohlhoff S,Gwyn S,Martin DL

更新日期：2018-03-09 00:00:00

abstract：:New high-frequency 5G and satellite communication systems require fully-metallic antennas and electromagnetic components. These components can be implemented with truncated versions of periodic structures. In order to achieve the desired performance of these future devices, it is of crucial importance to have a precis...

journal_title：Scientific reports

authors： Ghasemifard F,Norgren M,Quevedo-Teruel O

更新日期：2018-07-26 00:00:00

abstract：:Flexible thermoelectric generators (TEGs) can provide uninterrupted, green energy from body-heat, overcoming bulky battery configurations that limit the wearable-technologies market today. High-throughput production of flexible TEGs is currently dominated by printing techniques, limiting material choices and performan...

journal_title：Scientific reports

authors： Morgan KA,Tang T,Zeimpekis I,Ravagli A,Craig C,Yao J,Feng Z,Yarmolich D,Barker C,Assender H,Hewak DW

更新日期：2019-03-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ghazizadeh E,Moosavifard SE,Daneshmand N,Kaverlavani SK

更新日期：2020-08-11 00:00:00

abstract：:The claim that organic agriculture produces higher levels of phytochemicals has been controversial for decades. Using strawberries as a model crop in field conditions, a preharvest leaf wounding stress was applied to study the production of phytochemicals in fruits. As a result phenolic compounds (PCs) and total solub...

journal_title：Scientific reports

authors： Ibanez F,Bang WY,Lombardini L,Cisneros-Zevallos L

更新日期：2019-12-17 00:00:00

abstract：:Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 ad...

journal_title：Scientific reports

authors： Butkevich E,Härtig W,Nikolov M,Erck C,Grosche J,Urlaub H,Schmidt CF,Klopfenstein DR,Chua JJ

更新日期：2016-06-01 00:00:00

abstract：:Delivery and expression of recombinant genes, a key methodology for many applications in biological research, remains a challenge especially for mature neurons. Here, we report easy, highly efficient and well tolerated transduction of adult peripheral and central neuronal populations of diverse species in culture usin...

journal_title：Scientific reports

authors： Levin E,Diekmann H,Fischer D

更新日期：2016-12-13 00:00:00

abstract：:Increasing evidence suggest that the glucose-lowering drug metformin exerts a valuable anti-senescence role. The ability of metformin to affect the biogenesis of selected microRNAs (miRNAs) was recently suggested. MicroRNA isoforms (isomiRs) are distinct variations of miRNA sequences, harboring addition or deletion of...

journal_title：Scientific reports

authors： Giuliani A,Londin E,Ferracin M,Mensà E,Prattichizzo F,Ramini D,Marcheselli F,Recchioni R,Rippo MR,Bonafè M,Rigoutsos I,Olivieri F,Sabbatinelli J

更新日期：2020-12-11 00:00:00

abstract：:Enterococcus faecium is a commensal of the mammalian gastrointestinal tract, but is also found in non-enteric environments where it can grow between 10 °C and 45 °C. E. faecium has recently emerged as a multi-drug resistant nosocomial pathogen. We hypothesized that genes involved in the colonization and infection of m...

journal_title：Scientific reports

authors： Guzmán Prieto AM,Urbanus RT,Zhang X,Bierschenk D,Koekman CA,van Luit-Asbroek M,Ouwerkerk JP,Pape M,Paganelli FL,Wobser D,Huebner J,Hendrickx AP,Bonten MJ,Willems RJ,van Schaik W

更新日期：2015-12-17 00:00:00

abstract：:The development of a low-cost, fast, and large-scale process for the synthesis and manipulation of nanostructured metal oxides is essential for incorporating materials with diverse practical applications. Herein, we present a facile one-pot synthesis method using combustion waves that simultaneously achieves fast redu...

journal_title：Scientific reports

authors： Shin J,Lee KY,Yeo T,Choi W

更新日期：2016-02-23 00:00:00

abstract：:Autophagy is a protective and life-sustaining process in which cytoplasmic components are packaged into double-membrane vesicles and targeted to lysosomes for degradation. Accumulating evidence supports that autophagy is associated with several pathological conditions. However, research on the functional cross-links b...

journal_title：Scientific reports

authors： Wang JY,Yao WX,Wang Y,Fan YL,Wu JB

更新日期：2017-03-15 00:00:00

abstract：:In fish, the fat content contributes to promoting the nutritional and organoleptic characteristics of the flesh, which is crucial for consumer acceptance. Methods to predict the fat in fish are important in nutritional and physiological research, where body content is traditionally determined by dissection followed by...

journal_title：Scientific reports

authors： Ceballos-Francisco D,García-Carrillo N,Cuesta A,Esteban MÁ

更新日期：2020-06-29 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousands of healthy donors and are being tested in preclinical mouse models. Inherent challenges, however, are the pluripotency of IVIG and its xenogeneicity in animals. IVIG can alter the viability of human neutrophils v...

journal_title：Scientific reports

authors： Schneider C,Wicki S,Graeter S,Timcheva TM,Keller CW,Quast I,Leontyev D,Djoumerska-Alexieva IK,Käsermann F,Jakob SM,Dimitrova PA,Branch DR,Cummings RD,Lünemann JD,Kaufmann T,Simon HU,von Gunten S

更新日期：2017-05-02 00:00:00

abstract：:Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening and diagnosis. This labor-intensive task could greatly benefit from automatic detection usi...

journal_title：Scientific reports

authors： Sahlsten J,Jaskari J,Kivinen J,Turunen L,Jaanio E,Hietala K,Kaski K

更新日期：2019-07-24 00:00:00

abstract：:We have previously demonstrated that the Thymus algeriensis and Thymus fontanesii extracts have powerful anti-inflammatory, antipyretic, and analgesic effects against acute pain models. We profiled their chemical composition and found many phenolic acids, flavonoids, and phenolic diterpenes. In this work, we investiga...

journal_title：Scientific reports

authors： Rezq S,Alsemeh AE,D'Elia L,El-Shazly AM,Monti DM,Sobeh M,Mahmoud MF

更新日期：2020-11-25 00:00:00

abstract：:Multiple factors help shape the infant intestinal microbiota early in life. Environmental conditions such as the presence of bioactive molecules from breast milk dictate gut microbial growth and survival. Infants also receive distinct, personalized, bacterial exposures leading to differential colonization. Microbial e...

journal_title：Scientific reports

authors： Lewis ZT,Sidamonidze K,Tsaturyan V,Tsereteli D,Khachidze N,Pepoyan A,Zhgenti E,Tevzadze L,Manvelyan A,Balayan M,Imnadze P,Torok T,Lemay DG,Mills DA

更新日期：2017-02-02 00:00:00

abstract：:Plant seed germination is a crucial developmental event that has significant effects on seedling establishment and yield production. This process is controlled by multiple intrinsic signals, particularly phytohormones. The gaseous hormone ethylene stimulates seed germination; however, the genetic basis of ethylene pro...

journal_title：Scientific reports

authors： Kong D,Fu X,Jia X,Wang W,Li Y,Li J,Yang X,Ju C

更新日期：2020-02-03 00:00:00

abstract：:We successfully realised plasmon-driven selective reduction reactions of 2-amino-5-nitrobenzenethiol (2A-5-NBT) to 3,3'-dimercapto-4,4'-diaminoazobenzene , an azobenzene derivative, using surface-enhanced Raman scattering (SERS) spectroscopy, and supported by the theoretical calculations. The SERS spectra demonstrated...

journal_title：Scientific reports

authors： Ding Q,Chen M,Li Y,Sun M

更新日期：2015-06-01 00:00:00

abstract：:A difficult problem in quantum network communications is how to efficiently transmit quantum information over large-scale networks with common channels. We propose a solution by developing a quantum encoding approach. Different quantum states are encoded into a coherent superposition state using quantum linear optics....

journal_title：Scientific reports

authors： Luo MX,Xu G,Chen XB,Yang YX,Wang X

更新日期：2014-04-02 00:00:00

abstract：:Signaling by members of the transforming growth factor-β (TGF-β) superfamily, such as TGF-β3 and BMP7, and oxygen tension play a pivotal role in chondrocyte biology. The objective of this research was to investigate the endogenous BMP7 expression in human osteoarthritis (OA) cartilage and the effect of oxygen tension ...

journal_title：Scientific reports

authors： Huang X,Zhong L,Post JN,Karperien M

更新日期：2018-07-06 00:00:00

abstract：:The basic leucine zipper (bZIP) is a widely known transcription factors family in eukaryotes. In plants, the role of bZIP proteins are crucial in various biological functions such as plant growth and development, seed maturation, response to light signal and environmental stress. To date, bZIP protein family has been ...

journal_title：Scientific reports

authors： Li H,Li L,ShangGuan G,Jia C,Deng S,Noman M,Liu Y,Guo Y,Han L,Zhang X,Dong Y,Ahmad N,Du L,Li H,Yang J

更新日期：2020-09-23 00:00:00

abstract：:Automated image analysis of cells and tissues has been an active research field in medical informatics for decades but has recently attracted increased attention due to developments in computer and microscopy hardware and the awareness that scientific and diagnostic pathology require novel approaches to perform object...

journal_title：Scientific reports

authors： Wienert S,Heim D,Saeger K,Stenzinger A,Beil M,Hufnagl P,Dietel M,Denkert C,Klauschen F

更新日期：2012-01-01 00:00:00

abstract：:Beaver have been referred to as ecosystem engineers because of the large impacts their dam building activities have on the landscape; however, the benefits they may provide to fluvial fish species has been debated. We conducted a watershed-scale experiment to test how increasing beaver dam and colony persistence in a ...

journal_title：Scientific reports

authors： Bouwes N,Weber N,Jordan CE,Saunders WC,Tattam IA,Volk C,Wheaton JM,Pollock MM

更新日期：2016-07-04 00:00:00

abstract：:Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient stress. In Escheric...

journal_title：Scientific reports

authors： Chowdhury N,Kwan BW,Wood TK

更新日期：2016-02-03 00:00:00

abstract：:Biopharming for the production of recombinant pharmaceutical proteins in the mammary gland of transgenic animals is an attractive but laborious alternative compared to mammalian cell fermentation. The disadvantage of the lengthy process of genetically modifying an entire animal could be circumvented with somatic trans...

journal_title：Scientific reports

authors： Wagner S,Thresher R,Bland R,Laible G

更新日期：2015-10-14 00:00:00

abstract：:Two types of periodic and transient motions of large woodpeckers are considered. A drumming woodpecker may be modeled as a harmonic oscillator with a periodic forcing function. The transient behavior that occurs after the forcing is turned off suggests that the double knocks of Campephilus woodpeckers may be modeled i...

journal_title：Scientific reports

authors： Collins MD

更新日期：2017-10-02 00:00:00

abstract：:The maternal environment can influence the intensity of seed dormancy and thus seasonal germination timing and post-germination life history traits. We tested the hypotheses that germination season influences phenotypic expression of post-germination life history traits in the cold desert annual Isatis violascens and ...

journal_title：Scientific reports

authors： Lu JJ,Tan DY,Baskin CC,Baskin JM

更新日期：2016-04-27 00:00:00

abstract：:Current approaches to predicting a cardiovascular disease (CVD) event rely on conventional risk factors and cross-sectional data. In this study, we applied machine learning and deep learning models to 10-year CVD event prediction by using longitudinal electronic health record (EHR) and genetic data. Our study cohort i...

journal_title：Scientific reports

authors： Zhao J,Feng Q,Wu P,Lupu RA,Wilke RA,Wells QS,Denny JC,Wei WQ

更新日期：2019-01-24 00:00:00