Abstract:
PURPOSE:To examine the role of systemic medication on the risk of pseudophakic cystoid macular edema (PCME) following uneventful cataract surgery. METHODS:A total of 269 eyes undergoing routine cataract surgery. Spectral-domain optical coherence tomography imaging was conducted before surgery and at 28 days. Information about medication of the participants was gathered from The National Archive of Health Information (Kanta), an electronic pharmaceutical database. RESULTS:Systemic medication with angiotensin converting enzyme inhibitor/angiotensin II receptor antagonists (p < 0.001), beta-blockers (β-blockers) (p = 0.002), calcium channel blockers (CCBs) (p < 0.001), nitrates (p =0.021) and lipophilic HMG-CoA reductase inhibitors (statins) (p < 0.001) were more frequently prescribed to diabetic compared with nondiabetic patients. In eyes with steroid monotherapy (N = 135), concomitant systemic medication with β-blockers (12.9 ± 24.0 μm versus 28.6 ± 59.5 μm, p = 0.045), CCBs (12.0 ± 22.1 μm versus 26.3 ± 55.6 μm, p = 0.041) and statins (12.9 ± 22.8 μm versus 30.0 ± 61.9 μm, p = 0.038) attenuated a change in central retinal thickness (CRT) when compared to patients not receiving medication. In multivariable analysis, the use of CCBs remained as an independent protective factor against macular swelling at 28 days (-0.23; 95% CI [-0.43 to -0.04]; p = 0.021), when all systemic medications showing statistical significance were included (i.e. β-blockers, CCBs and statins) together with diabetes status. In eyes with nonsteroidal anti-inflammatory drug (NSAID) monotherapy (N = 67) and steroid and NSAID combination therapy (N = 67), CRT increase was moderate both with and without use of systemic medications. CONCLUSION:Systemic vasoactive medication may be protective against CRT change induced by cataract surgery in eyes at risk of PCME such as those with postoperative steroid monotherapy.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Danni R,Taipale C,Holmström EJ,Ilveskoski L,Tuuminen Rdoi
10.1111/aos.13911subject
Has Abstractpub_date
2019-03-01 00:00:00pages
178-184issue
2eissn
1755-375Xissn
1755-3768journal_volume
97pub_type
杂志文章abstract:PURPOSE:Photoscreening assesses risk factors for amblyopia, as an alternative to measurement of visual acuity (VA) to detect amblyopia, on the premise that its early correction could prevent development of amblyopia. We studied implementations of Plusoptix photoscreening in existing population-based screening in Flande...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.14144
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To evaluate the prognosis of mortality in patients with spontaneous subarachnoid haemorrhage associated with Terson's syndrome. METHODS:A prospective, consecutive case series study was conducted in patients admitted to the emergency room with a diagnosis of acute subarachnoid haemorrhage. After a complete neur...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01735.x
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To examine the public health impact of presbyopia regarding its effect on quality of life (QoL) and society in both the developed and developing worlds. METHODS:A database was created from articles found on PubMed, the Cochrane Library and Science Direct using the following search terms: presbyopia, QoL, accom...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.12308
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:Current evidence indicates that alteration in ocular blood flow may be relevant in open-angle glaucoma (OAG) patients independent of intraocular pressure (IOP). Presently, the lack of an adequate methodology capable of assessing all vascular beds limits the clinical role of blood flow parameters in glaucoma man...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0420.2007.01091.x
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To investigate the amount of systemic oxidative stress-related DNA damage and serum total antioxidant status of patients with normal-tension glaucoma compared with healthy controls. METHODS:Forty-three patients with normal-tension glaucoma selected from 60 consecutive newly diagnosed patients with primary open...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01997.x
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13665
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To investigate the intravitreal levels of potent vasoactive, angiogenic and extracellular matrix remodelling factors in the diabetic patients with simvastatin treatment. METHODS:This is an institutional, prospective, observational case-control study. Type-1 and type-2 diabetic patients on lipophilic simvastati...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12363
更新日期:2014-11-01 00:00:00
abstract::The development of ophthalmology was greatly restricted in Poland in the 19th century, because it was partitioned and occupied by its three dominant neighbours. Polish medical universities were closed, and in Polish hospitals, only clinical work was possible. Those who wanted to study medicine and become ophthalmologi...
journal_title:Acta ophthalmologica
pub_type: 历史文章,杂志文章
doi:10.1111/j.1755-3768.2009.01856.x
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS:Thirty-seven 3-8 years old c...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13536
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To describe the different clinical presentations of periocular molluscum contagiosum (MC) lesions and their epidemiological, clinical and histopathological features. METHODS:Medical records and histopathological sections of all cases of periocular MC treated at the oculoplastic clinic of the Goldschleger Eye I...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13717
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals. METHODS:Twenty-six healthy participants underwent moderate dynamic exercise (modified Master's two-step exercise). In all subjects, intraocular pressures (IOP), systolic and diastolic blood pressures (SBP and...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13576
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To explore the association between retinal vein occlusion (RVO) and incident cancer. METHODS:All Danish citizens with a first-time diagnosis of RVO and no previous diagnosis of cancer in the period from 1 January 2004 to 31 December 2014 were included. Five likewise cancer-free, age- and gender-matched control...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/aos.13860
更新日期:2018-12-01 00:00:00
abstract::Our review aims to provide an update of management protocols for congenital nasolacrimal duct obstruction (CNDO). Although early probing performed before the age of 1 year was traditionally recommended, many reports have since confirmed high frequencies of spontaneous resolution during the first year of life. Accordin...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2009.01592.x
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To report the accuracy of intraocular lens (IOL) power estimation in eyes that have undergone phacovitrectomy for retinal diseases with accompanying macular oedema. METHODS:A retrospective study was conducted in 23 eyes of 23 patients at Soonchunhyang University Hospital, Seoul, Korea. The relationship between...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01752.x
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Retinal Vessel Analyser (RVA) is a validated instrument to measure retinal vessel diameter in humans. The purpose of this study was to assess the reproducibility (inter-observer reliability) and the repeatability (test-retest reliability) of RVA with a microscope-mounted fundus camera to determine retinal vesse...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02374.x
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:Using OCT-A to investigate the association between neurodegeneration and vascular morphology in diabetic retinopathy (DR). METHODS:Cross-sectional study. One hundred and sixty-two patients were enrolled and following fundoscopy were assigned to two groups according to DR severity: 54 patients to the group of n...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14754
更新日期:2021-01-10 00:00:00
abstract::Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2008.01210.x
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:The computer program laguna onhe determines optic nerve head haemoglobin (ONH Hb) on retinal photographs based on detecting colour differences. This study compares the diagnostic capacity of Laguna ONhE with that of spectral domain optical coherence tomography (OCT) and confocal tomography (HRT III). METHODS:I...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13050
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To investigate whether introduction of item-response theory (IRT) analysis, in parallel to the 'traditional' statistical analysis methods available for performance evaluation of multiple T/F items as used in the European Board of Ophthalmology Diploma (EBOD) examination, has proved beneficial, and secondly, to ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12135
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To evaluate the outcome of a prospective protocol for the treatment of chronic central serous chorioretinopathy (CSC). METHODS:Interventional prospective case series in 59 eyes (59 patients) with active chronic CSC. All patients were first treated with indocyanine green angiography (ICGA)-guided half-dose phot...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12938
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:We report the epidemiology, findings, treatment, long-term outcome and use of resources for eye injuries caused by toy guns in southern Finland. METHODS:All new patients injured by toy guns in one year (2011-2012) and treated at Helsinki University Eye Hospital were included. Follow-ups occurred at 3 months an...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13948
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To characterize frequency, morphological cause and time-dependent change of boundary line artefacts in optical coherence tomography (OCT) examinations of centre-involved diabetic macular oedema (ciDME) patients who underwent ranibizumab treatment with 1-year follow-up and to evaluate the impact of artefacts on ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12494
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:Study purpose was to investigate the effects of bariatric surgery on intraocular pressure (IOP) and other ophthalmic parameters in a prospective observational follow-up study. METHODS:Ophthalmic examination was performed on 22 obese women before and 6 months after bariatric surgery. A control group of 15 non-o...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13826
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:We set out to quantify changes in the anterior chamber volume (ACV), anterior chamber depth (ACD) and anterior chamber angle (ACA) measurements obtained by the Pentacam rotating Scheimpflug camera following uneventful phacoemulsification surgery in normotensive eyes with open iridocorneal angles. METHODS:We en...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01305.x
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13047
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To evaluate the potential use of decellularized porcine stromal matrix (PSM) for reconstruction of corneal stroma in a rabbit model. METHODS:Ten chinchilla bastard rabbit corneas were exposed to a circular half-thickness keratotomy with a 3.0 mm diameter at the central cornea. Porcine corneas were decellulariz...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02300.x
更新日期:2012-05-01 00:00:00
abstract::Ziv-aflibercept (Zaltrap® ), a recombinant fusion protein that binds diffusible vascular endothelial growth factor (VEGF), is approved for the treatment of metastatic colorectal carcinoma. Its molecular structure is the same as aflibercept (Eylea® ), thus making it an attractive option for the off-label treatment of c...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14328
更新日期:2019-12-20 00:00:00
abstract:PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/aos.13234
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To evaluate association of the van Herick (VH) grades with the ultrasound biomicroscopic (UBM) parameters, appositional irido-trabecular contact (A-ITC) and plateau iris (PI) in a randomly sampled population. METHODS:A 10% random sample of all residents aged 40 or older of the Kumejima study underwent UBM unde...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14502
更新日期:2020-06-22 00:00:00
abstract:PURPOSE:To evaluate microperimetric changes 1year after macular hole surgery with triamcinolone acetonide assisted internal limiting membrane (ILM) peeling. METHODS:Twenty-two eyes of 22 patients with stage 3 and 4 idiopathic macular holes of <6months' duration underwent vitrectomy with triamcinolone acetonide assiste...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01898.x
更新日期:2010-09-01 00:00:00