当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Structural features of polysaccharides from edible jambo (Syzygium jambos) fruits and antitumor activity of extracted pectins.

Structural features of polysaccharides from edible jambo (Syzygium jambos) fruits and antitumor activity of extracted pectins.

Abstract：

:Jambo is a tropical fruit cultivated in Southeast Asia and tropical regions of America and Africa. After extraction, its polysaccharides were structurally characterized. Water soluble polysaccharides (WSP) were composed of GalA:Ara:Gal:Glc:Rha in 51:22:16:5:6 molar ratio, indicating the presence of pectic polysaccharides. Methylation analysis and NMR spectroscopy indicated the presence of homogalacturonan (HG), type II arabinogalactan and type I rhamnogalacturonan (RG-I). The HG/RG-I ratio was 88%, indicating greater amounts of smooth than hairy pectic regions. Hemicellulosic polysaccharides were extracted from the residue and fractionated by freeze-thaw procedure in two fractions (ASP-S and ASP-I). ASP-S was composed of Glc:Gal:Xyl:Ara:Man:Fuc:UA in a 45:16:20:3:8:5:2 molar ratio. Methylation analysis and 13C NMR spectroscopy indicated xyloglucan, xylan and mannan. Their relative proportion estimated on sugar linkage was 89%, 6% and 3%, respectively. ASP-I was composed mainly of xylose (99.5%) and its 13C NMR indicated a linear (1 → 4)-β-D-xylan. The biological activity of WSP was tested in Ehrlich tumor-bearing mice. After 21 days of oral treatment, the doses of 150 and 250 mg/kg WSP reduced expressively the tumor growth, similarly to the positive control methotrexate, and improved the body weight of tumor-bearing mice. Further studies are necessary to investigate the mechanisms of the WSP antitumor effect.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Tamiello CS,Adami ER,de Oliveira NMT,Acco A,Iacomini M,Cordeiro LMC

doi

10.1016/j.ijbiomac.2018.06.164

subject

Has Abstract

pub_date

2018-10-15 00:00:00

pages

1414-1421

issue

Pt B

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(18)30894-8

journal_volume

118

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Physicochemical properties of pectin from green jelly leaf (Cyclea barbata Miers).

    abstract：:The water extract of Green Jelly leaves (GJL) obtained by crushing the leaves in water (1:40) was capable of forming a gel at room temperature. The composition of GJL consisted mainly of carbohydrate (∼70w/w), protein (∼13% w/w) and minerals (∼6% w/w). The mineral portion consisted of mainly calcium (∼1.2% w/w), zinc ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.05.147

    authors： Yuliarti O,Chong SY,Goh KKT

    更新日期：2017-10-01 00:00:00

  • Preferential recognition of advanced glycation end products by serum antibodies and low-grade systemic inflammation in diabetes mellitus and its complications.

    abstract：BACKGROUND:Advanced glycation end products (AGEs) have shown to possess antigenicity. This study analyzes the detrimental effect of non-enzymatic glycation on human serum albumin (HSA) leading to the production of antibodies. METHODS:HSA (20 μM) incubated with d-glucose formed AGEs confirmed by scanning electron micro...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.07.033

    authors： Raghav A,Ahmad J,Alam K

    更新日期：2018-10-15 00:00:00

  • Zinc alginate-carboxymethyl cashew gum microbeads for prolonged drug release: development and optimization.

    abstract：:Isoxsuprine HCl-loaded microbeads using sodium alginate (SA)-carboxymethyl cashew gum (CMCG) polymer-blends were developed through ionotropic-gelation technique using ZnSO4 as cross-linker. Effects of polymer-blend ratio and cross-linker concentration on drug encapsulation efficiency (DEE) and cumulative drug release ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.07.030

    authors： Das B,Dutta S,Nayak AK,Nanda U

    更新日期：2014-09-01 00:00:00

  • Two classes of cytochrome P450 reductase genes and their divergent functions in Camptotheca acuminata Decne.

    abstract：:Cytochrome P450 monooxygenases (CYP450s) and their auxiliary cytochrome P450 reductases (CPRs) are important and commonly involved in the biosynthesis of camptothecin (CPT). To better understand the possible functions of CPRs in planta, we first isolated two CaCPRs genes from Camptotheca acuminata. Sequence analysis r...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.07.141

    authors： Jin Z,Cong Y,Zhu S,Xing R,Zhang D,Yao X,Wan R,Wang Y,Yu F

    更新日期：2019-10-01 00:00:00

  • Electrospinning of multifunctional cellulose acetate membrane and its adsorption properties for ionic dyes.

    abstract：:Electrospinning of cellulose acetate with appropriated solvent system is the most straightforward method for fabricating micro- and nanofibers. To simultaneously and effectively remove both cationic and anionic dyes, a novel cost-effective multifunctional cellulose acetate (CA) fibers membrane was prepared by electros...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.04.249

    authors： Chen W,Ma H,Xing B

    更新日期：2020-05-03 00:00:00

  • Molecular aspects on the specific interaction of cytotoxic plant alkaloid palmatine to poly(A).

    abstract：:The interaction of the protoberberine alkaloid palmatine with single and double stranded structures of poly(A) was studied by various biophysical techniques. Comparative binding studies were also performed with double stranded DNA, t-RNA, poly(C).poly(G), poly(U) and poly(C). The results of competition dialysis, fluor...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2006.03.026

    authors： Giri P,Hossain M,Kumar GS

    更新日期：2006-11-15 00:00:00

  • TRIP13 is a predictor for poor prognosis and regulates cell proliferation, migration and invasion in prostate cancer.

    abstract：:Thyroid hormone receptor interactor 13 (TRIP13) has been reported to be overexpressed in serval types of human cancers, and regulate tumor cell proliferation, migration and invasion. However, the role of TRIP13 in prostate cancer was still unclear. In our study, the correlation between TRIP13 expression and clinical p...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.09.168

    authors： Dong L,Ding H,Li Y,Xue D,Li Z,Liu Y,Zhang T,Zhou J,Wang P

    更新日期：2019-01-01 00:00:00

  • Anti-inflammatory activity of polysaccharides from Phellinus linteus by regulating the NF-κB translocation in LPS-stimulated RAW264.7 macrophages.

    abstract：:Inflammatory response remains one of the most common and serious complications of disease. In order to profound understanding relationship between Phellinus linteus polysaccharides (TCM) and inflammation, inflammatory cell model was constructed by LPS acting RAW264.7 cell line. The results showed that TCM could decrea...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.02.023

    authors： Xie Z,Wang Y,Huang J,Qian N,Shen G,Chen L

    更新日期：2019-05-15 00:00:00

  • Selective adsorption of Pd (II) by ion-imprinted porous alginate beads: Experimental and density functional theory study.

    abstract：:In this study, a novel thiourea grafted porous sodium alginate-based adsorbent was synthesized by combining ion-imprinting and direct templating method. Due to ion-imprinting, the prepared adsorbent has demonstrated outstanding selectivity towards Pd (II) from bi-metallic solution at different pH values. Langmuir and ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.04.153

    authors： Gao X,Guo C,Hao J,Zhao Z,Long H,Li M

    更新日期：2020-08-15 00:00:00

  • Crowded milieu tuning the stability and activity of stem bromelain.

    abstract：:Proteins in vivo are under an extremely crowded environment because of the presence of bulky and large biological macromolecules (known as crowders). These crowders affect the proper functioning and structure of proteins in a cell. During in vitro studies, we often ignore the effect of macromolecular crowding on prote...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.12.060

    authors： Bhakuni K,Venkatesu P

    更新日期：2018-04-01 00:00:00

  • Acidic depolymerization vs ionic liquid solubilization in lignin extraction from eucalyptus wood using the protic ionic liquid 1-methylimidazolium chloride.

    abstract：:Protic ionic liquids have been proposed as effective solvents for the selective extraction of lignin from wood. In this work, the protic ionic liquid 1-methylimidazolium chloride has been used to extract lignin at different biomass loadings, temperatures, and times to understand the influence of treatment severity on ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.04.194

    authors： Ovejero-Pérez A,Rigual V,Domínguez JC,Alonso MV,Oliet M,Rodriguez F

    更新日期：2020-08-15 00:00:00

  • Effect of sulfated astragalus polysaccharide on cellular infectivity of infectious bursal disease virus.

    abstract：:Four kinds of astragalus polysaccharides (APSs), APS(t), APS(40), APS(50) and APS(60), were extracted by water decoction and one-step or stepwise ethanol precipitation methods, and modified by chlorosulfonic acid-pyridine method to obtain four sulfated APSs (sAPSs) (sAPS(t), sAPS(40), sAPS(50), sAPS(60)), respectively...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2007.10.019

    authors： Huang X,Wang D,Hu Y,Lu Y,Guo Z,Kong X,Sun J

    更新日期：2008-03-01 00:00:00

  • Optimization of Hericium erinaceus polysaccharide-loaded Poly (lactic-co-glycolicacid) nanoparticles by RSM and its absorption in Caco-2 cell monolayers.

    abstract：:In present study, HEP was successfully encapsulated into the Poly (lactic-coglycolicacid) (PLGA) to constitute the HEP-PLGA. The effects of three independent factors (the proper range of ratio of organic phase (o) to internal water phase (w1) (X1), ratio of external water phase (w2) to the primary emulsion (PE) (X2), ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.06.169

    authors： Ren Z,Qin T,Liu X,Luo Y,Qiu F,Long Y,Ma Y,Li J,Huang Y

    更新日期：2018-10-15 00:00:00

  • Organisation of the external region of the starch granule as determined by infrared spectroscopy.

    abstract：:Attenuated total reflectance-Fourier transform infrared (ATR-FTIR) was used to study the external regions of starch granules. Native starches (wheat, potato, maize, waxy maize and amylomaize) were analysed and compared to gelatinised and acid-hydrolysed starches. The IR spectra of potato and amylomaize starches were c...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/s0141-8130(02)00067-3

    authors： Sevenou O,Hill SE,Farhat IA,Mitchell JR

    更新日期：2002-12-20 00:00:00

  • Oral delivery of nanoparticles containing anticancer SN38 and hSET1 antisense for dual therapy of colon cancer.

    abstract：:An oral delivery system intended for treatment of colon cancer in HT29 cancerous cells was investigated by encapsulating hSET1 antisense and SN38 anticancer in nanoparticles based on cysteine trimethyl chitosan (cysTMC) and carboxymethyl dextran (CMD). Studies have shown hSET1 as the main type of histone methyltransfe...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.03.066

    authors： Dinarvand M,Kiani M,Mirzazadeh F,Esmaeili A,Mirzaie Z,Soleimani M,Dinarvand R,Atyabi F

    更新日期：2015-01-01 00:00:00

  • Non-toxic O-quaternized chitosan materials with better water solubility and antimicrobial function.

    abstract：:Five water-soluble O-quaternary ammonium salt-chitosans (QAS-CS) bearing N-methyl-N-R-N, N-bis(2-hydroxyethyl) ammonium bromides (R=-benzyl (chloride, BNQAS-CS), -dodecyl (C12QAS-CS), -tetradecyl (C14QAS-CS), -hexadecyl (C16QAS-CS), -octadecyl (C18QAS-CS)) were prepared, respectively. They were characterized by FTIR, ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.12.047

    authors： Wang CH,Liu WS,Sun JF,Hou GG,Chen Q,Cong W,Zhao F

    更新日期：2016-03-01 00:00:00

  • Chaperone-like activity of heme group against amyloid-like fibril formation by hen egg ovalbumin: possible mechanism of action.

    abstract：:It is well accepted that porphyrins related to heme, are effectively able to act as pharmaceutical. For instance, they were found to interfere with the aggregation of beta-amyloid peptide. In present study, the influence of heme concentration on the amyloid-type aggregation of ovalbumin was investigated. We provided e...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2008.10.011

    authors： Khodarahmi R,Soori H,Karimi SA

    更新日期：2009-01-01 00:00:00

  • Enhanced mechanical and hydrophobic properties of composite cassava starch films with stearic acid modified MCC (microcrystalline cellulose)/NCC (nanocellulose) as strength agent.

    abstract：:The green composite cassava starch films were prepared using stearic acid modified microcrystalline cellulose (M-MCC)/nanocellulose (M-NCC) as strength agent, which shows good mechanical and hydrophobic properties and is a candidate for food package in this work. Microcrystalline cellulose (MCC) was prepared with 98% ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.10.024

    authors： Chen Q,Shi Y,Chen G,Cai M

    更新日期：2020-01-01 00:00:00

  • Preparation and properties of cellulose nanocomposite films with in situ generated copper nanoparticles using Terminalia catappa leaf extract.

    abstract：:In the present work, copper nanoparticles (CuNPs) were in situ generated inside cellulose matrix using Terminalia catappa leaf extract as a reducing agent. During this process, some CuNPs were also formed outside the matrix. The CuNPs formed outside the matrix were observed with transmission electron microscope (TEM) ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.09.114

    authors： Muthulakshmi L,Rajini N,Nellaiah H,Kathiresan T,Jawaid M,Rajulu AV

    更新日期：2017-02-01 00:00:00

  • Ca2+-induced stabilization of the nucleoside 2'- deoxyribosyltransferase from Lactobacillus hilgardii ZJS01: Characteristics and application in nucleosides synthesis.

    abstract：:A novel nucleoside 2'-deoxyribosyltransferase (LhNDT) from Lactobacillus hilgardii ZJS01 was cloned and expressed in Escherichia coli BL21 (DE3). The amino acid sequence of LhNDT displayed the highest identity of 26% to other reported NDTs. LhNDT was a monomer as revealed by gel filtration chromatography with or witho...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.08.104

    authors： Zhang J,Zhou Y,Liu K,Chu J,Zhang Y,He B

    更新日期：2018-01-01 00:00:00

  • Novel spider web trap approach based on chitosan/cellulose nanocrystals/glycerol membrane for the detection of Escherichia coli O157:H7 on food surfaces.

    abstract：:The aim of this study was to develop a novel approach allowing simultaneous enrichment as well as specific and fast detection of Escherichia coli O157:H7 by indirect ELISA using optimized support membrane based on chitosan (CHI), cellulose nanocrystals (CNCs), and glycerol (GLY). Therefore, combining the step of the c...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.09.225

    authors： Baraketi A,D'Auria S,Shankar S,Fraschini C,Salmieri S,Menissier J,Lacroix M

    更新日期：2020-03-01 00:00:00

  • Development of the PVA/CS nanofibers containing silk protein sericin as a wound dressing: In vitro and in vivo assessment.

    abstract：:Skin and soft tissue infections are major concerns with respect to wound repair. Recently, anti-bacterial wound dressings have been emerging as promising candidates to reduce infection, thus accelerating the wound healing process. This paper presents our work to develop and characterize poly(vinyl alcohol) (PVA)/chito...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.01.139

    authors： Bakhsheshi-Rad HR,Ismail AF,Aziz M,Akbari M,Hadisi Z,Omidi M,Chen X

    更新日期：2020-04-15 00:00:00

  • pH-sensitive sodium alginate/poly(vinyl alcohol) hydrogel beads prepared by combined Ca2+ crosslinking and freeze-thawing cycles for controlled release of diclofenac sodium.

    abstract：:In order to enhance the drug entrapment efficiency and improve the swelling behaviors of drug delivery system, Ca2+ crosslinking and freeze-thawing (FT) cycle techniques were used to prepare sodium alginate/poly(vinyl alcohol) (SA/PVA) hydrogel beads. The mixture solution of SA and PVA was firstly crosslinked with Ca2...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2010.03.004

    authors： Hua S,Ma H,Li X,Yang H,Wang A

    更新日期：2010-06-01 00:00:00

  • Multi-analysis of chemical transformations of lignin macromolecules from waterlogged archaeological wood.

    abstract：:A large number of archaeological wooden building poles have been excavated from the Hai Menkou site (Yunnan province, China). Lignin can be transformed and altered accompanied with significant loss of carbohydrates during this process. Elucidation of chemical and structural transformations of lignin is of primary impo...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.12.114

    authors： Xia Y,Chen TY,Wen JL,Zhao YL,Qiu J,Sun RC

    更新日期：2018-04-01 00:00:00

  • Characterization of exopolysaccharides produced by microalgae with antitumor activity on human colon cancer cells.

    abstract：:The physicochemical characteristics, antioxidant and antitumor activities of partial purified exopolysaccharides from microalgae Chlorella pyrenoidosa FACHB-9, Scenedesmus sp. and Chlorococcum sp. were investigated. The molecular weights were 1.94 × 105, 7.39 × 103 and 3.24 × 104 g/mol, respectively. Monosaccharide an...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.02.009

    authors： Zhang J,Liu L,Ren Y,Chen F

    更新日期：2019-05-01 00:00:00

  • Aggregative protein-polyelectrolyte complex for high-concentration formulation of protein drugs.

    abstract：:Aggregative protein-polyelectrolyte complex (PPC) has been proposed as a concentrated state of protein with a great potential for biopharmaceutical application. In this review article, we introduce a unique concentration method of protein formulation using PPC for a dozen types of pharmaceutical antibodies, hormones, ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2016.06.016

    authors： Kurinomaru T,Shiraki K

    更新日期：2017-07-01 00:00:00

  • Characterization by mass spectrometry of poly(3-hydroxyalkanoates) produced by Rhodospirillum rubrum from 3-hydroxyacids.

    abstract：:The sequence distributions of two microbial copolyesters obtained by fermentation of Rhodospirillum rubrum, grown with 3-hydroxyhexanoic or 3-hydroxyheptanoic acids, were determined by analyzing the oligomers prepared by partial pyrolysis or partial methanolysis of these copolyesters using fast atom bombardment mass s...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/s0141-8130(99)00085-9

    authors： Ballistreri A,Giuffrida M,Impallomeni G,Lenz RW,Fuller RC

    更新日期：1999-11-01 00:00:00

  • Extraction, purification and antibacterial activities of a polysaccharide from spent mushroom substrate.

    abstract：:To contribute towards effective exploitation and utilization of spent mushroom substrate (SMS), a water-soluble polysaccharide named PL was isolated and purified from SMS. The total sugar content and monosaccharide composition were analyzed by phenol-sulfuric acid method and capillary electrophoresis, and infrared spe...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2011.11.016

    authors： Zhu H,Sheng K,Yan E,Qiao J,Lv F

    更新日期：2012-04-01 00:00:00

  • Fabrication of letrozole formulation using chitosan nanoparticles through ionic gelation method.

    abstract：:In this study, the anticancer drug letrozole (LTZ) was formulated using chitosan nanoparticles (CS-NPs) with the crosslinking agent sodium tripolyphosphate (TPP). The nano-formulation was optimized by varying the concentration of drug. The prepared particles were characterized using FTIR, TGA, XRD, SEM, TEM and DLS. F...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.01.147

    authors： Gomathi T,Sudha PN,Florence JAK,Venkatesan J,Anil S

    更新日期：2017-11-01 00:00:00

  • Chemical characteristics and immuno-modulating activities of exo-biopolymers produced by Grifola frondosa during submerged fermentation process.

    abstract：:The immuno-modulating activities and chemical characteristics of exo-biopolymer (EX-GF) produced by a submerged mycelial culture of Grifola frondosa were studied. The EX-GF was fractionated into EX-GF-Fr.I, II, and III by Sephadex G-100 gel chromatography. Anti-complementary activity of EX-GF-Fr.III was highest (71.1%...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2007.02.012

    authors： Yang BK,Gu YA,Jeong YT,Jeong H,Song CH

    更新日期：2007-08-01 00:00:00