Mixed support for a causal link between single dose intranasal oxytocin and spiritual experiences: opposing effects depending on individual proclivities for absorption.

Abstract:

:Intranasal oxytocin (OT) has previously been found to increase spirituality, an effect moderated by OT-related genotypes. This pre-registered study sought to conceptually replicate and extend those findings. Using a single dose of intranasal OT vs placebo (PL), we investigated experimental treatment effects, and moderation by OT-related genotypes on spirituality, mystical experiences, and the sensed presence of a sentient being. A more exploratory aim was to test for interactions between treatment and the personality disposition absorption on these spirituality-related outcomes. A priming plus sensory deprivation procedure that has facilitated spiritual experiences in previous studies was used. The sample (N = 116) contained both sexes and was drawn from a relatively secular context. Results failed to conceptually replicate both the main effects of treatment and the treatment by genotype interactions on spirituality. Similarly, there were no such effects on mystical experiences or sensed presence. However, the data suggested an interaction between treatment and absorption. Relative to PL, OT seemed to enhance spiritual experiences in participants scoring low in absorption and dampen spirituality in participants scoring high in absorption.

authors

Cortes DS,Skragge M,Döllinger L,Laukka P,Fischer H,Nilsson ME,Hovey D,Westberg L,Larsson M,Granqvist P

doi

10.1093/scan/nsy068

subject

Has Abstract

pub_date

2018-09-11 00:00:00

pages

921-932

issue

9

eissn

1749-5016

issn

1749-5024

pii

5077396

journal_volume

13

pub_type

杂志文章
  • Racial ingroup and outgroup attention biases revealed by event-related brain potentials.

    abstract::Recent electrophysiological research indicates that perceivers differentiate others on the basis of race extremely quickly. However, most categorization studies have been limited to White participants, neglecting potential differences in processing between racial groups. Moreover, the extent to which race interferes w...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsm012

    authors: Dickter CL,Bartholow BD

    更新日期:2007-09-01 00:00:00

  • Ventromedial prefrontal cortex and the regulation of physiological arousal.

    abstract::Neuroimaging studies show a correlation between activity of the ventromedial prefrontal cortex (vmPFC) and skin conductance measurements. However, little is known whether this brain region plays a causal role in regulating physiological arousal. To address this question, we employed Granger causality analysis (GCA) to...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nst064

    authors: Zhang S,Hu S,Chao HH,Ide JS,Luo X,Farr OM,Li CS

    更新日期:2014-07-01 00:00:00

  • Motivation alters impression formation and related neural systems.

    abstract::Observers frequently form impressions of other people based on complex or conflicting information. Rather than being objective, these impressions are often biased by observers' motives. For instance, observers often downplay negative information they learn about ingroup members. Here, we characterize the neural system...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsw147

    authors: Hughes BL,Zaki J,Ambady N

    更新日期:2017-01-01 00:00:00

  • Intrinsic connectivity in the human brain does not reveal networks for 'basic' emotions.

    abstract::We tested two competing models for the brain basis of emotion, the basic emotion theory and the conceptual act theory of emotion, using resting-state functional connectivity magnetic resonance imaging (rs-fcMRI). The basic emotion view hypothesizes that anger, sadness, fear, disgust and happiness each arise from a bra...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv013

    authors: Touroutoglou A,Lindquist KA,Dickerson BC,Barrett LF

    更新日期:2015-09-01 00:00:00

  • Social anxiety modulates amygdala activation during social conditioning.

    abstract::Aversive social learning experiences might play a significant role in the aetiology of social anxiety disorder. Therefore, we investigated emotional learning and unlearning processes in healthy humans using a social conditioning paradigm. Forty-nine healthy subjects participated in a 2-day fMRI differential conditioni...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsr095

    authors: Pejic T,Hermann A,Vaitl D,Stark R

    更新日期:2013-03-01 00:00:00

  • Individual differences in neural correlates of fear conditioning as a function of 5-HTTLPR and stressful life events.

    abstract::Fear learning is a crucial process in the pathogeneses of psychiatric disorders, which highlights the need to identify specific factors contributing to interindividual variation. We hypothesized variation in the serotonin transporter gene (5-HTTLPR) and stressful life events (SLEs) to be associated with neural correla...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nss005

    authors: Klucken T,Alexander N,Schweckendiek J,Merz CJ,Kagerer S,Osinsky R,Walter B,Vaitl D,Hennig J,Stark R

    更新日期:2013-03-01 00:00:00

  • Gender-specific expression of the DRD4 gene on adolescent delinquency, anger and thrill seeking.

    abstract::The present study investigated gender differences in the associations between the DRD4 variable number tandem repeat (VNTR) polymorphism and adolescent delinquency, short temper and thrill seeking. We also explored whether the gender-specific expression of the DRD4 can be explained by gender differences in the exposur...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsq020

    authors: Dmitrieva J,Chen C,Greenberger E,Ogunseitan O,Ding YC

    更新日期:2011-01-01 00:00:00

  • When opposites lead to the same: a direct comparison of explicit and implicit disgust regulation via fMRI.

    abstract::Cognitive reappraisal and placebo administration constitute two different approaches for modulating one's own emotional state. Whereas reappraisal is an explicit (effortful) type of self-regulation, placebo treatment initiates implicit processes of affective control. The brain mechanisms underlying these processes hav...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsw144

    authors: Schienle A,Übel S,Wabnegger A

    更新日期:2017-03-01 00:00:00

  • Psychopathic traits are associated with cortical and subcortical volume alterations in healthy individuals.

    abstract::Research suggests psychopathy is associated with structural brain alterations that may contribute to the affective and interpersonal deficits frequently observed in individuals with high psychopathic traits. However, the regional alterations related to different components of psychopathy are still unclear. We used vox...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv062

    authors: Vieira JB,Ferreira-Santos F,Almeida PR,Barbosa F,Marques-Teixeira J,Marsh AA

    更新日期:2015-12-01 00:00:00

  • Deconstructing the brain's moral network: dissociable functionality between the temporoparietal junction and ventro-medial prefrontal cortex.

    abstract::Research has illustrated that the brain regions implicated in moral cognition comprise a robust and broadly distributed network. However, understanding how these brain regions interact and give rise to the complex interplay of cognitive processes underpinning human moral cognition is still in its infancy. We used func...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nss139

    authors: Feldmanhall O,Mobbs D,Dalgleish T

    更新日期:2014-03-01 00:00:00

  • Dual brain stimulation enhances interpersonal learning through spontaneous movement synchrony.

    abstract::Social interactive learning denotes the ability to acquire new information from a conspecific-a prerequisite for cultural evolution and survival. As inspired by recent neurophysiological research, here we tested whether social interactive learning can be augmented by exogenously synchronizing oscillatory brain activit...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsaa080

    authors: Pan Y,Novembre G,Song B,Zhu Y,Hu Y

    更新日期:2021-01-18 00:00:00

  • Coordinated activation of premotor and ventromedial prefrontal cortices during vicarious reward.

    abstract::The vicarious reward we receive from watching likable others obtaining a positive outcome is a pervasive phenomenon, yet its neural correlates are poorly understood. Here, we conducted a series of functional magnetic resonance imaging experiments to test the hypothesis that the brain areas responsible for action obser...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv134

    authors: Shimada S,Matsumoto M,Takahashi H,Yomogida Y,Matsumoto K

    更新日期:2016-03-01 00:00:00

  • Wait, what? Assessing stereotype incongruities using the N400 ERP component.

    abstract::Numerous discoveries regarding stereotypes have been uncovered by utilizing techniques and methods developed by cognitive psychologists. The present study continues this tradition by borrowing psychophysiological techniques used for the study of memory and language, and applying them to the study of stereotypes. In th...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsp004

    authors: White KR,Crites SL Jr,Taylor JH,Corral G

    更新日期:2009-06-01 00:00:00

  • OXTR polymorphism predicts social relationships through its effects on social temperament.

    abstract::Humans have a fundamental need for strong interpersonal bonds, yet individuals differ appreciably in their degree of social integration. That these differences are also substantially heritable has spurred interest in biological mechanisms underlying the quality and quantity of individuals' social relationships. We pro...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsu132

    authors: Creswell KG,Wright AG,Troxel WM,Ferrell RE,Flory JD,Manuck SB

    更新日期:2015-06-01 00:00:00

  • Subsequent Memory Effects on Event-Related Potentials in Associative Fear Learning.

    abstract::Studies of human fear learning suggest that a reliable discrimination between safe and threatening stimuli is important for survival and mental health. In the current study, we applied the subsequent memory paradigm in order to identify neurophysiological correlates of successful threat and safety learning. We recorde...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsab015

    authors: Wiemer J,Leimeister F,Pauli P

    更新日期:2021-02-01 00:00:00

  • Music models aberrant rule decoding and reward valuation in dementia.

    abstract::Aberrant rule- and reward-based processes underpin abnormalities of socio-emotional behaviour in major dementias. However, these processes remain poorly characterized. Here we used music to probe rule decoding and reward valuation in patients with frontotemporal dementia (FTD) syndromes and Alzheimer's disease (AD) re...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsx140

    authors: Clark CN,Golden HL,McCallion O,Nicholas JM,Cohen MH,Slattery CF,Paterson RW,Fletcher PD,Mummery CJ,Rohrer JD,Crutch SJ,Warren JD

    更新日期:2018-02-01 00:00:00

  • Cognitive benefit and cost of acute stress is differentially modulated by individual brain state.

    abstract::Acute stress is associated with beneficial as well as detrimental effects on cognition in different individuals. However, it is not yet known how stress can have such opposing effects. Stroop-like tasks typically show this dissociation: stress diminishes speed, but improves accuracy. We investigated accuracy and speed...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/scan/nsx043

    authors: Kohn N,Hermans EJ,Fernández G

    更新日期:2017-07-01 00:00:00

  • Dissociable patterns of brain activity for mentalizing about known others: a role for attachment.

    abstract::The human brain tracks dynamic changes within the social environment, forming and updating representations of individuals in our social milieu. This mechanism of social navigation builds an increasingly complex map of persons with whom we are familiar and form attachments to guide adaptive social behaviors. We examine...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsx040

    authors: Laurita AC,Hazan C,Spreng RN

    更新日期:2017-07-01 00:00:00

  • Cool, callous and in control: superior inhibitory control in frequent players of video games with violent content.

    abstract::Research on the effects of media violence exposure has shown robust associations among violent media exposure, increased aggressive behavior, and decreased empathy. Preliminary research indicates that frequent players of violent video games may have differences in emotional and cognitive processes compared to infreque...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsx115

    authors: Stockdale L,Morrison RG,Palumbo R,Garbarino J,Silton RL

    更新日期:2017-12-01 00:00:00

  • Neural correlates of aberrant emotional salience predict psychotic symptoms and global functioning in high-risk and first-episode psychosis.

    abstract::Neurobiological and behavioral findings suggest that psychosis is associated with corticolimbic hyperactivity during the processing of emotional salience. This has not been widely studied in the early stages of psychosis, and the impact of these abnormalities on psychotic symptoms and global functioning is unknown. We...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv035

    authors: Modinos G,Tseng HH,Falkenberg I,Samson C,McGuire P,Allen P

    更新日期:2015-10-01 00:00:00

  • The effect of acute tryptophan depletion on emotional distraction and subsequent memory.

    abstract::Serotonin is a key neurotransmitter involved in emotional regulation and memory. A number of studies using acute tryptophan depletion (ATD) in healthy subjects have shown that a temporary serotonin reduction both induces a negative emotional bias and impairs long-term memory. However, little is known about the specifi...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1093/scan/nsp025

    authors: Wang L,Mullette-Gillman OA,Gadde KM,Kuhn CM,McCarthy G,Huettel SA

    更新日期:2009-12-01 00:00:00

  • Functional mechanisms involved in the internal inhibition of taboo words.

    abstract::The present study used functional magnetic resonance imaging to investigate brain processes associated with the inhibition of socially undesirable speech. It is tested whether the inhibition of undesirable speech is solely related to brain areas associated with classical stop signal tasks or rather also involves brain...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsr030

    authors: Severens E,Kühn S,Hartsuiker RJ,Brass M

    更新日期:2012-04-01 00:00:00

  • Neural measures of the causal role of observers' facial mimicry on visual working memory for facial expressions.

    abstract::Simulation models of facial expressions propose that sensorimotor regions may increase the clarity of facial expressions representations in extrastriate areas. We monitored the event-related potential marker of visual working memory (VWM) representations, namely the sustained posterior contralateral negativity (SPCN),...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsy095

    authors: Sessa P,Schiano Lomoriello A,Luria R

    更新日期:2018-12-04 00:00:00

  • Medial cortex activity, self-reflection and depression.

    abstract::Using functional magnetic resonance imaging, we investigated neural activity associated with self-reflection in depressed [current major depressive episode (MDE)] and healthy control participants, focusing on medial cortex areas previously shown to be associated with self-reflection. Both the MDE and healthy control g...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsp022

    authors: Johnson MK,Nolen-Hoeksema S,Mitchell KJ,Levin Y

    更新日期:2009-12-01 00:00:00

  • Confidence of emotion expression recognition recruits brain regions outside the face perception network.

    abstract::Metacognitive beliefs about emotions expressed by others are crucial to social life, yet very little studied. To what extent does our confidence in emotion expression recognition depend on perceptual or other non-perceptual information? We obtained behavioral and magnetic resonance imaging measures while participants ...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsy102

    authors: Bègue I,Vaessen M,Hofmeister J,Pereira M,Schwartz S,Vuilleumier P

    更新日期:2019-01-04 00:00:00

  • Neurocognitive Processing of Infant Stimuli in Mothers and Non-Mothers: Psychophysiological, Cognitive and Neuroimaging Evidence.

    abstract::Emerging evidence indicates that mothers and non-mothers show different neurocognitive responses to infant stimuli. This study investigated mothers' psychophysiological, cognitive and neuronal responses to emotional infant stimuli. A total of 35 mothers with four months old infants and 18 control women without young c...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsab002

    authors: Bjertrup A,Friis N,Væver M,Miskowiak K

    更新日期:2021-01-09 00:00:00

  • Neural mechanisms of social influence in adolescence.

    abstract::During the transformative period of adolescence, social influence plays a prominent role in shaping young people's emerging social identities, and can impact their propensity to engage in prosocial or risky behaviors. In this study, we examine the neural correlates of social influence from both parents and peers, two ...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv095

    authors: Welborn BL,Lieberman MD,Goldenberg D,Fuligni AJ,Galván A,Telzer EH

    更新日期:2016-01-01 00:00:00

  • A voxel-based lesion study on facial emotion recognition after penetrating brain injury.

    abstract::The ability to read emotions in the face of another person is an important social skill that can be impaired in subjects with traumatic brain injury (TBI). To determine the brain regions that modulate facial emotion recognition, we conducted a whole-brain analysis using a well-validated facial emotion recognition task...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nss041

    authors: Dal Monte O,Krueger F,Solomon JM,Schintu S,Knutson KM,Strenziok M,Pardini M,Leopold A,Raymont V,Grafman J

    更新日期:2013-08-01 00:00:00

  • Morning brain: Real-world neural evidence that high school class times matter.

    abstract::Researchers, parents, and educators consistently observe a stark mismatch between biologically preferred and socially imposed sleep-wake hours in adolescents, fueling debate about high school start times. We contribute neural evidence to this debate with electroencephalogram (EEG) data collected from high school stude...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsaa142

    authors: Dikker S,Haegens S,Bevilacqua D,Davidesco I,Wan L,Kaggen L,McClintock J,Chaloner K,Ding M,West T,Poeppel D

    更新日期:2020-10-17 00:00:00

  • Neural substrates of classically conditioned fear-generalization in humans: a parametric fMRI study.

    abstract::Recent research on classical fear-conditioning in the anxiety disorders has identified overgeneralization of conditioned fear as an important conditioning correlate of anxiety pathology. Unfortunately, only one human neuroimaging study of classically conditioned fear generalization has been conducted, and the neural s...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nst096

    authors: Lissek S,Bradford DE,Alvarez RP,Burton P,Espensen-Sturges T,Reynolds RC,Grillon C

    更新日期:2014-08-01 00:00:00