EEG discrimination of perceptually similar tastes.

abstract：:In contrast to mammals, teleost fish are able to regrow severed long-range projection axons in the central nervous system (CNS), leading to recovery of function. The optic projection in teleost fish is used to study neuron-intrinsic and environmental molecular factors that determine successful axon regrowth and naviga...

journal_title：Journal of neuroscience research

authors： Becker CG,Becker T

更新日期：2007-09-01 00:00:00

abstract：:Nociceptive neuronal activation in subcortical regions has not been well investigated in functional magnetic resonance imaging (fMRI) studies. The present report aimed to use the blood oxygenation level-dependent (BOLD) fMRI technique to map nociceptive responses in both subcortical and cortical regions by employing a...

journal_title：Journal of neuroscience research

authors： Shih YY,Chen YY,Chen CC,Chen JC,Chang C,Jaw FS

更新日期：2008-06-01 00:00:00

abstract：:Astrocytes are the most abundant glial cell in the central nervous system. They modulate synaptic function through a variety of mechanisms, and yet remain relatively understudied with respect to overall neuronal circuit function. Exploiting the tractability of the mouse olfactory system, we manipulated astrocyte activ...

journal_title：Journal of neuroscience research

authors： Ung K,Tepe B,Pekarek B,Arenkiel BR,Deneen B

更新日期：2020-08-01 00:00:00

abstract：:Deletion of the tumor suppressor gene p53 has been shown to improve the outcome in experimental models of focal cerebral ischemia and kainate-induced seizures. To evaluate the potential role of p53 in traumatic brain injury, genetically modified mice lacking a functional p53 gene (p53(-/-), n = 9) and their wild-type ...

journal_title：Journal of neuroscience research

authors： Tomasevic G,Raghupathi R,Scherbel U,Wieloch T,McIntosh TK

更新日期：2010-11-15 00:00:00

abstract：:Glutamate is an important regulator of dendrite development; however, during cerebral ischemia, massive glutamate release can lead to neurodegeneration and death. An early consequence of glutamate excitotoxicity is dendrite injury, which often precedes cell death. We examined the effect of glutamate on dendrite growth...

journal_title：Journal of neuroscience research

authors： Monnerie H,Shashidhara S,Le Roux PD

更新日期：2003-12-01 00:00:00

abstract：:We have developed an animal model of learning and memory impairment associated with activation of microglia in the mouse brain. Injection of lipopolysaccharide into the CA1 region of the mouse hippocampus resulted in an increased production of inflammatory cytokines, such as interleukin-1β. Immunostaining for interleu...

journal_title：Journal of neuroscience research

authors： Tanaka S,Kondo H,Kanda K,Ashino T,Nakamachi T,Sekikawa K,Iwakura Y,Shioda S,Numazawa S,Yoshida T

更新日期：2011-04-01 00:00:00

abstract：:The remarkable quantities of myelin membrane produced by oligodendrocytes has led us to examine the mechanisms involved in the sorting and transport of proteins and lipids during myelinogenesis. Noting that it has been proposed that proteins destined for the apical surface of polarized epithelial cells co-cluster with...

journal_title：Journal of neuroscience research

authors： Kim T,Fiedler K,Madison DL,Krueger WH,Pfeiffer SE

更新日期：1995-10-15 00:00:00

abstract：:As aging population is increasing, new methodologies to apprehend and enhance the mechanisms related to optimal brain function in advancing age become urgent. This review describes how the combined use of non-invasive brain stimulation (NIBS) with functional magnetic resonance imaging (fMRI) provides novel experimenta...

journal_title：Journal of neuroscience research

authors： Abellaneda-Pérez K,Vaqué-Alcázar L,Solé-Padullés C,Bartrés-Faz D

更新日期：2019-08-16 00:00:00

abstract：:We reported previously that stem cell factor (SCF) is produced mainly by neurons and that its receptor (c-kitR), encoded by the protooncogene c-kit, is expressed in microglia, suggesting that SCF/c-kitR signaling may be involved in neuron-microglia interactions. We now report that SCF supports microglial survival in c...

journal_title：Journal of neuroscience research

authors： Zhang SC,Fedoroff S

更新日期：1998-07-01 00:00:00

abstract：:We have determined the localization of Cav1.2 (L-Type) Ca2+ channels in the cells and nerve fibers in molars of normal or injured rats. We observed high levels of immunostaining of L-type Ca2+ channels in odontoblast cell bodies and their processes, in fibroblast cell bodies and in Schwann cells. Many Cav1.2-containin...

journal_title：Journal of neuroscience research

authors： Westenbroek RE,Anderson NL,Byers MR

更新日期：2004-02-01 00:00:00

abstract：:In this report, we address the molecular mechanisms that regulate axonal growth by focusing on the gene for one of the major axonal cytoskeletal proteins, T alpha1 alpha-tubulin. During the developmental growth of sympathetic neurons, transcription of a beta-galactosidase transgene driven by the T alpha1 promoter (T a...

journal_title：Journal of neuroscience research

authors： Wu W,Gloster A,Miller FD

更新日期：1997-06-01 00:00:00

abstract：:Production of hydrogen peroxide as a by-product of the breakdown of catecholamines by the enzyme monoamine oxidase (MAO) has been hypothesized to contribute to the increased proclivity of dopaminergic neurons for oxidative injury. We established clonal dopaminergic PC12 cell lines which have elevated MAO activity leve...

journal_title：Journal of neuroscience research

authors： Wei Q,Yeung M,Jurma OP,Andersen JK

更新日期：1996-12-15 00:00:00

abstract：:The postmortem stability of brain RNA was measured in rat and human samples for up to 48 hr. Whole rat brains, cooled at a rate approximating that of human brains awaiting autopsy, were collected at intervals from 0 to 48 hr after death and frozen. These samples were compared with freshly obtained, unfrozen rat brains...

journal_title：Journal of neuroscience research

authors： Johnson SA,Morgan DG,Finch CE

更新日期：1986-01-01 00:00:00

abstract：:The expression of gangliosides of the lactosylceramide (LC) and of the gangliotetraosylceramide (GTC) series on the surface of cells from rat embryonic cerebellar tissue was investigated by double-color indirect immunofluorescence. GD3 was assumed to be representative of LC and was detected using a specific monoclonal...

journal_title：Journal of neuroscience research

authors： Gravotta D,Ferreira A,Busciglio J,Caceres A,Landa CA,Maccioni HJ

更新日期：1990-02-01 00:00:00

abstract：:The expression of different muscarinic receptor subtypes was analyzed in immature Schwann cells obtained from sciatic nerve of 2-day neonatal rats. By using RT-PCR analysis, we demonstrated the presence of M1, M2, M3, and M4 receptor subtypes in cultured Schwann cells, with M2 displaying the highest expression levels....

journal_title：Journal of neuroscience research

authors： Loreti S,Vilaró MT,Visentin S,Rees H,Levey AI,Tata AM

更新日期：2006-07-01 00:00:00

abstract：:The presence of oligodendrocyte precursor cells which cannot be removed from primary cultures by antibody-dependent techniques complicates the interpretation of transplantation experiments designed to examine the potential of astrocytes to influence remyelination (Blakemore et al.; Glia 13:79-91, 1995). In the present...

journal_title：Journal of neuroscience research

authors： Crang AJ,Blakemore WF

更新日期：1997-07-01 00:00:00

abstract：:Lithium, the most prevalent treatment for manic-depressive illness, might have a neuroprotective effect after brain injury. In culture, lithium can exert neurotoxic effects associated with reduction in polyamine synthesis but neuroprotective effects as cultured neurons mature. Cumulative evidence suggests that lithium...

journal_title：Journal of neuroscience research

authors： Gilad GM,Gilad VH

更新日期：2007-02-15 00:00:00

abstract：:The hypoxia-responsive cytokine erythropoietin (EPO) provides neuroprotective effects in the damaged brain during ischemic events and neurodegenerative diseases. The purpose of the present study is to evaluate the EPO/EPO receptor (EPOR) endogenous system between astrocyte and oligodendrocyte precursor cell (OPC) unde...

journal_title：Journal of neuroscience research

authors： Kato S,Aoyama M,Kakita H,Hida H,Kato I,Ito T,Goto T,Hussein MH,Sawamoto K,Togari H,Asai K

更新日期：2011-10-01 00:00:00

abstract：:Glutamate, the major excitatory neurotransmitter, induces a signal from the membrane to the nucleus that regulates gene expression. The gene encoding the chick kainate binding protein undergoes a glutamate-dependent transcriptional regulation via an activator protein-1 site within its promoter region. To characterize ...

journal_title：Journal of neuroscience research

authors： Aguirre A,López-Bayghen E,Ortega A

更新日期：2002-10-01 00:00:00

abstract：:The transplantation of dopaminergic (DA) progenitors derived from pluripotent stem cells improves the behavior of Parkinson's disease model animals. However, the survival of DA progenitors is low, and the final yield of DA neurons is only approximately 0.3%-2% the number of transplanted cells. Zonisamide (ZNS) increas...

journal_title：Journal of neuroscience research

authors： Miyawaki Y,Samata B,Kikuchi T,Nishimura K,Takahashi J

更新日期：2020-08-01 00:00:00

abstract：:The chronic constriction injury (CCI) of the sciatic nerve is a nerve injury-based model of neuropathic pain (NP). Comorbidities of NP such as depression, anxiety, and cognitive deficits are associated with a functional reorganization of the medial prefrontal cortex (mPFC). Here, we have employed an adapted model of C...

journal_title：Journal of neuroscience research

authors： Medeiros P,de Freitas RL,Boccella S,Iannotta M,Belardo C,Mazzitelli M,Romano R,De Gregorio D,Coimbra NC,Palazzo E,Maione S

更新日期：2020-02-01 00:00:00

abstract：:Antiglycolipid IgM antibodies are known to induce formation of "wide spaced" or "expanded" myelin, a distinctive form of dysmyelination characterized by a repeat period approximately two or three times normal, which is seen also in diseases, including multiple sclerosis. To determine whether an antibody directed again...

journal_title：Journal of neuroscience research

authors： Rosenbluth J,Schiff R

更新日期：2009-03-01 00:00:00

abstract：:Taurine, 2-aminoethanesulfonic acid, is present at high concentrations in many invertebrate and vertebrate systems and has several biological functions. In addition, it has been related to a neuroprotective role against several diseases such as epilepsy. In the present work, we treated mice with taurine and examined i...

journal_title：Journal of neuroscience research

authors： Junyent F,Romero R,de Lemos L,Utrera J,Camins A,Pallàs M,Auladell C

更新日期：2010-01-01 00:00:00

abstract：:The effect of neonatal hyperthyroidism produced by injection of tri-iodothyronine (T3) on myelination and on the microperoxisomal population of the brain was studied in young rats. Data on the lipid composition of myelin show that myelinogenesis starts earlier in treated animals. In coincidence with the early appearan...

journal_title：Journal of neuroscience research

authors： Adamo AM,Aloise PA,Soto EF,Pasquini JM

更新日期：1990-03-01 00:00:00

abstract：:Perinatal hypoxic-ischemic (HI)-related brain injury is an important cause of morbidity and long-standing disability in newborns. The only currently approved therapeutic strategy available to reduce brain injury in the newborn is hypothermia. Therapeutic hypothermia can only be used to treat HI encephalopathy in full-...

journal_title：Journal of neuroscience research

authors： Disdier C,Stonestreet BS

更新日期：2020-07-01 00:00:00

abstract：:We used a modified pial vessel disruption (PVD) protocol with adult male Wistar rats to mimic small-vessel stroke in the cerebral cortex. Within 3 weeks, this lesion develops into a single lacuna-like cavity, which is fluid-filled and encapsulated by reactive astrocytes. Minocycline treatment that commences 1 hr after...

journal_title：Journal of neuroscience research

authors： Cayabyab FS,Gowribai K,Walz W

更新日期：2013-07-01 00:00:00

abstract：:The ability of altered environmental conditions to modulate some properties of synaptosomes has been studied. Incubation conditions used included the presence of methyl mercury or an organochlorine insecticide: chlordecone. Other adverse chemical conditions during incubation were the absence of calcium salts from the ...

journal_title：Journal of neuroscience research

authors： Bondy SC,McKee M

更新日期：1990-02-01 00:00:00

abstract：:Raf kinases are downstream effectors of Ras and upstream activators of the MEK-ERK cascade. Ras and MEK-ERK signaling play roles in learning and memory (L&M) and neural plasticity, but the roles of Raf kinases in L&M and plasticity are unclear. Among Raf isoforms, B-raf is preferentially expressed in the brain. To det...

journal_title：Journal of neuroscience research

authors： Chen AP,Ohno M,Giese KP,Kühn R,Chen RL,Silva AJ

更新日期：2006-01-01 00:00:00

abstract：:Previous studies have shown that PC12 cells overexpressing beta/A4 amyloid peptide display altered morphology characterized by pronounced membrane ruffling and extensive intercellular appositions. Having observed other cell types in which these features accompany increased connexin43 (Cx43) production and gap junction...

journal_title：Journal of neuroscience research

authors： Nagy JI,Hossain MZ,Hertzberg EL,Marotta CA

更新日期：1996-04-15 00:00:00

abstract：:The incubation of murine thymocytes for 24 hr in the presence of cholinergic agonists induces selective proliferation of PNA- cells as measured by thymidine incorporation. The response of PNA- cells is mediated by the activation of nicotinic receptors. This conclusion is suggested by the inability of the muscarinic ag...

journal_title：Journal of neuroscience research

authors： Rossi A,Tria MA,Baschieri S,Doria G,Frasca D

更新日期：1989-11-01 00:00:00