Abstract:
:Southern blot analyses of surgical specimens of cervical carcinoma from Japanese patients showed that 3/9 samples contained human papillomavirus (HPV) type-16 DNA sequences, and 2 contained HPV type-18 DNA sequences. By Northern blot analyses, RNA transcripts of HPV DNA sequences were demonstrated in some of the tissues containing HPV type-16 or HPV type-18 DNA sequences. Two cell lines established from cervical cancers of Japanese patients also contained HPV type-18 genomes and these cell lines contained HPV type-18 transcripts. Two other cervical cancer cell lines from a Japanese patient were found to contain HPV type-16 DNA sequences and their RNA transcripts.
journal_name
Int J Cancerjournal_title
International journal of cancerauthors
Tsunokawa Y,Takebe N,Nozawa S,Kasamatsu T,Gissmann L,zur Hausen H,Terada M,Sugimura Tdoi
10.1002/ijc.2910370405subject
Has Abstractpub_date
1986-04-15 00:00:00pages
499-503issue
4eissn
0020-7136issn
1097-0215journal_volume
37pub_type
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