Abstract：
:DNA extracts of several rosy-mutation-bearing strains were associated with large insertions and deletions in a defined region of the molecular map believed to include the rosy locus DNA. Large-scale, intragenic mapping experiments were carried out that localized these mutations within the boundaries of the previously defined rosy locus structural element. Molecular characterization of the wild-type recombinants provides conclusive evidence that the rosy locus DNA is localized to the DNA segment marked by these lesions. One of the mutations, ry2101, arose from a P-M hybrid dysgenesis experiment and is associated with a copia insertion. Experiments are described which suggest that copia mobilizes in response to P-M hybrid dysgenesis. Relevance of the data to recombination in higher organisms is considered.
journal_name
Geneticsjournal_title
Geneticsauthors
Clark SH,McCarron M,Love C,Chovnick Asubject
Has Abstractpub_date
1986-04-01 00:00:00pages
755-67issue
4eissn
0016-6731issn
1943-2631journal_volume
112pub_type
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