Stage and tissue-specific expression of a collagen gene during Drosophila melanogaster development.

Abstract:

:Based on data from developmental RNA profiles and in situ hybridization, we report a direct examination of the expression of one collagen gene (Dcg1) during drosophila melanogaster life cycle. These studies show, for the first time, that the expression of a collagen gene is both differential and tissue-specific during the course of development. Moreover, they demonstrate that the connective tissues in Drosophila do contain a collagen type synthesized by mesodermal tissues. Indeed the accumulation of Dcg1 transcripts was located mainly within the second instar fat bodies, the third instar lymph glands, and over adepithelial cells associated with third instar imaginal discs. In addition, these results seem to confirm the interpretation that wandering hemocytes released by the lymph glands could contribute in extracellular matrix composition in some tissues in the larva.

journal_name

Exp Cell Res

authors

Le Parco Y,Knibiehler B,Cecchini JP,Mirre C

doi

10.1016/0014-4827(86)90071-6

subject

Has Abstract

pub_date

1986-04-01 00:00:00

pages

405-12

issue

2

eissn

0014-4827

issn

1090-2422

journal_volume

163

pub_type

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