Abstract:
:Hypereosinophilic syndrome is a myeloproliferative disorder characterized by persistent eosinophilia with involvement of multiple organs. The occurrence of severe pulmonary hypertension (PH) in the setting of hypereosinophilic syndrome is very uncommon. A 43-year-old man with documented idiopathic hypereosinophlic syndrome presented to the hospital with symptoms of paroxysmal chest discomfort and progressive exertional dyspnea. Physical examination showed distended jugular veins, cyanosed lips, increased P2 sound, and moderate pitting edema of the lower extremities. Echocardiography revealed enlarged right atrium, enlarged right ventricle, increased pulmonary artery systolic pressure, and decreased right ventricular systolic function. Venous ultrasound of the lower extremities, computed tomography pulmonary angiography, and right heart catheterization (RHC) were negative for thrombus. The pulmonary artery systolic pressure was found severely increased during the RHC. Treatment included prednisolone, ambrisentan, diuretics, and digoxin. The involvement of the pulmonary artery in patients with idiopathic hypereosinophilic syndrome is an uncommon finding. The patient presents with clinical manifestations of right ventricular systolic dysfunction resulted from severely increased PH.
journal_name
Pulm Circjournal_title
Pulmonary circulationauthors
Zhang L,Peng X,Adhikari BK,Li B,Liu Q,Mikeladze J,Zhang Wdoi
10.1177/2045894018793999subject
Has Abstractpub_date
2019-01-01 00:00:00pages
2045894018793999issue
1eissn
2045-8932issn
2045-8940journal_volume
9pub_type
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journal_title:Pulmonary circulation
pub_type: 杂志文章
doi:10.1177/2045894018773044
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journal_title:Pulmonary circulation
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doi:10.1177/2045894018760166
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journal_title:Pulmonary circulation
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doi:10.1177/2045894018798921
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abstract::The biological mechanisms behind the development of pulmonary hypertension in the setting of left heart failure (HF-PH), including combined pre- and post-capillary pulmonary hypertension (Cpc-PH), remains unclear. This study aimed to use candidate polymorphisms in nitric oxide synthase (NOS) genes to explore the role ...
journal_title:Pulmonary circulation
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doi:10.1177/2045894018773049
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journal_title:Pulmonary circulation
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doi:10.1177/2045893217739807
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journal_title:Pulmonary circulation
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doi:10.1177/2045894018817741
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abstract::Pathological alterations of inspiratory capacity (IC) have been observed in pulmonary hypertension. However, the clinical significance of IC in operable chronic thromboembolic pulmonary hypertension (CTEPH) without other pulmonary diseases remains unknown. CTEPH patients scheduled for pulmonary endarterectomy were pro...
journal_title:Pulmonary circulation
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journal_title:Pulmonary circulation
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Pulmonary circulation
pub_type: 杂志文章
doi:10.4103/2045-8932.101407
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journal_title:Pulmonary circulation
pub_type: 杂志文章
doi:10.4103/2045-8932.113184
更新日期:2013-04-01 00:00:00
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journal_title:Pulmonary circulation
pub_type: 杂志文章
doi:10.1177/2045894018819781
更新日期:2018-12-03 00:00:00
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journal_title:Pulmonary circulation
pub_type:
doi:10.1086/682227
更新日期:2015-09-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1086/674307
更新日期:2013-09-01 00:00:00
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doi:10.1177/2045894020941352
更新日期:2020-10-26 00:00:00
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journal_title:Pulmonary circulation
pub_type: 杂志文章
doi:10.1086/677361
更新日期:2014-09-01 00:00:00
abstract:: ...
journal_title:Pulmonary circulation
pub_type: 杂志文章
doi:10.1177/2045894019865158
更新日期:2019-07-03 00:00:00
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pub_type: 杂志文章
doi:10.1177/2045894019845610
更新日期:2019-04-01 00:00:00
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journal_title:Pulmonary circulation
pub_type:
doi:10.1086/683687
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更新日期:2011-04-01 00:00:00
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journal_title:Pulmonary circulation
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journal_title:Pulmonary circulation
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