The role of functional thyroid capacity in pituitary thyroid feedback regulation.

abstract：:The aim of this study was to assess the effect of intravenous dextran on bacterial translocation and intestinal vascular endothelial and epithelial barrier function after experimental partial hepatectomy. We determined systemic arterial pressure, enteric bacterial growth (proximal and distal small intestine and colon)...

journal_title：European journal of clinical investigation

authors： Wang XO,Sun ZW,Soltesz V,Deng XM,Andersson R

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Augmentation index (AIx) is a measure of arterial wave reflection, providing information on the workload of the heart. and is a possible marker for cardiovascular disease risk. The relation of alcohol consumption with cardiovascular disease (CVD) risk is U-shaped with a protective effect of moderate alcohol ...

journal_title：European journal of clinical investigation

authors： van Trijp MJ,Bos WJ,van der Schouw YT,Muller M,Grobbee DE,Bots ML

更新日期：2005-10-01 00:00:00

abstract：:Increased cardiovascular mortality is an unresolved problem in patients with chronic renal failure. Cardiac hypertrophy is observed in the majority of patients with chronic renal failure undergoing haemodialysis. However, the mechanisms, including signal transduction pathways, responsible for cardiac hypertrophy in re...

journal_title：European journal of clinical investigation

authors： Takahashi H,Takeishi Y,Miyamoto T,Shishido T,Arimoto T,Konta T,Miyashita T,Ito M,Kubota I

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Nowadays there is an increased interest in the role of aortic stiffness in the pathophysiology of heart failure (HF), as it is a major determinant of left ventricular (LV) performance. We aimed at assessing the predictive value of the aortic stiffness parameters, measured by echocardiography, in patients aff...

journal_title：European journal of clinical investigation

authors： Sciatti E,Vizzardi E,Bonadei I,Fabbricatore D,Prati F,Pagnoni M,Metra M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Graves' disease (GD) is an autoimmune disorder characterized by hyperthyroidism, which can relapse in many patients after antithyroid drug treatment withdrawal. Several studies have been performed to predict the clinical course of GD in patients treated with antithyroid drugs, without conclusive results. The...

journal_title：European journal of clinical investigation

authors： Orunesu E,Bagnasco M,Salmaso C,Altrinetti V,Bernasconi D,Del Monte P,Pesce G,Marugo M,Mela GS

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Variation of percentageCD4+ T cells may accurately reflects the kinetics of a comprehensive immune recovery independently of the antiretroviral (ART) regimen. To test this we have investigated the relationship among peripheral blood T-cell subsets with the variation of percentageCD4+ T cells during follow up...

journal_title：European journal of clinical investigation

authors： Resino S,Bellón JM,Gurbindo D,León JA,Muñoz-Fernández MA

更新日期：2003-07-01 00:00:00

abstract：:The effects of treating the anaemia of end-stage renal failure with erythropoietin were studied in nine dialysis patients. The increase in haemoglobin concentration (by 59% from 7.0 +/- 1.2 to 11.1 +/- 1.1 g dl-1) was associated with increases in exercise duration (by 41%) and maximum oxygen consumption (by 34%). Trea...

journal_title：European journal of clinical investigation

authors： Lewis NP,Macdougall IC,Willis N,Coles GA,Williams JD,Henderson AH

更新日期：1993-07-01 00:00:00

abstract：:Ten men with Klinefelter's syndrome were studied to assess the effect of testosterone replacement on plasma lipids and apolipoproteins. Measurements taken before the insertion of a testosterone ester implant were compared with those obtained 1 week and 4 weeks later. Mean plasma testosterone, androstenedione, total ch...

journal_title：European journal of clinical investigation

authors： Jones DB,Higgins B,Billet JS,Price WH,Edwards CR,Beastall GH,Shepherd J,Sweeting VM,Horn DB,Wenham PR

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Arterial calcification (AC) is a major health problem associated with extreme morbidity and a shortened survival. It is currently without any effective treatment. ATP and the purinergic system in general are now emerging as being important in the pathogenesis of AC and potentially provide a new focus for nov...

journal_title：European journal of clinical investigation

authors： Fish RS,Klootwijk E,Tam FW,Kleta R,Wheeler DC,Unwin RJ,Norman J

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:An earlier report described that transgenic mice ubiquitously expressing cryptochrome1 (CRY1) with a mutation in cystein414 (CRY1-AP Tg mice) display diabetes mellitus in addition to anomalous circadian behaviours. This study examined characteristic aspects of symptoms to clarify the diabetes type and pathog...

journal_title：European journal of clinical investigation

authors： Okano S,Hayasaka K,Igarashi M,Iwai H,Togashi Y,Nakajima O

更新日期：2010-11-01 00:00:00

abstract：:Deficient leucocyte sphingomyelinase activity has been demonstrated in a patient with the sea-blue histiocyte syndrome. Family studies revealed that two other cases previously diagnosed on clinical and histochemical criteria also had a pronounced diminution of sphingomyelinase activity. Both parents of the affected in...

journal_title：European journal of clinical investigation

authors： Fried K,Beer S,Krespin HI,Leiba H,Djaldetti M,Zitman D,Klibansky C

更新日期：1978-08-01 00:00:00

abstract：:Primary biliary cirrhosis and primary sclerosing cholangitis are well recognized chronic cholestatic liver diseases that are considered to have an autoimmune basis. Recent progress in the study of autoimmune liver diseases has improved the recognition and characterization of these conditions. An important component of...

journal_title：European journal of clinical investigation

authors： Medina J,Jones EA,García-Monzón C,Moreno-Otero R

更新日期：2001-01-01 00:00:00

abstract：:The effect of propranolol 160-640 mg/day for 3 months on the accelerated loss of bone matrix and mineral in hyperthyroidism was studied in seventeen patients. A rise in serum thyroxine (P less than 0.01) during the first 3 weeks was followed by a fall (P less than 0.02). Serum triiodothyronine declined during the stud...

journal_title：European journal of clinical investigation

authors： Mosekilde L,Jastrup B,Melsen F,Lund B,Lund B,Sørensen OH,Nielsen HE,Yde H

更新日期：1984-04-01 00:00:00

abstract：:Beta-thromboglobulin (beta TG), serotonin (5HT) and fibrinopeptide A (FPA) were assessed in twenty-two normal donors before, during, and at the end of leukapheresis. Seven procedures were carried out adding heparin to the circuit, and seven adding acetyl salicylic acid (ASA). The remaining eight procedures were carrie...

journal_title：European journal of clinical investigation

authors： Fabris F,Casonato A,Randi ML,Belloni M,Quaino V,Ongaro G,Girolami A

更新日期：1985-08-01 00:00:00

abstract：:The release of PGI2-like activity into the circulation in response to cholinergic agonists and modification of this response by beta-adrenergic antagonists was investigated in anaesthetized cats and healthy humans. Antiaggregatory activity in the arterial blood was continuously assayed by measuring platelet aggregatio...

journal_title：European journal of clinical investigation

authors： Swies J,Radomski M,Dembińska-Kieć A,Korbut R,Gryglewski RJ,Brandt R,Nowak J

更新日期：1985-12-01 00:00:00

abstract：:The studies were designed to explore the effect of the converting enzyme inhibitor captopril on the activity of the sympathetic nervous system during basal conditions and following graded physical exercise in patients with essential hypertension. Seven males and two females, aged 36-59 years, were hospitalized under m...

journal_title：European journal of clinical investigation

authors： Manhem P,Bramnert M,Hulthén UL,Hökfelt B

更新日期：1981-10-01 00:00:00

abstract：:The study aimed to assess vascular reactivity to noradrenaline with and without neuropeptide Y in diabetic rats, and to determine whether any abnormality could be attributed to insulin deficiency or to hyperglycaemia per se. The authors compared non-diabetic rats (n = 9) and rats with streptozotocin-induced diabetes t...

journal_title：European journal of clinical investigation

authors： Savage MW,Bodmer CW,Walker AB,Buchan IE,Masson EA,Williams G

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is an age-related neurodegenerative disorder that is characterized by a progressive loss of higher cognitive functions. The brain of an individual with AD exhibits extracellular senile plaques (SPs) of aggregated amyloid-beta peptide (Abeta) and intracellular neurofibrillary tangles ...

journal_title：European journal of clinical investigation

authors： Yokota T,Mishra M,Akatsu H,Tani Y,Miyauchi T,Yamamoto T,Kosaka K,Nagai Y,Sawada T,Heese K

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The DALI low-density lipoprotein (LDL) apheresis system is the first whole-blood apheresis system in regular clinical use. DALI stands for direct adsorption of lipoproteins, which describes the basic principle of operation of this newly developed LDL apheresis procedure. METHODS:The selective removal of LDL...

journal_title：European journal of clinical investigation

authors： Dräger LJ,Julius U,Kraenzle K,Schaper J,Toepfer M,Zygan K,Otto V,Steinhagen-Thiessen E

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Gastrointestinal symptoms are common on acute exposure to high-altitude (HA). Underlying mechanisms are not understood, but vascular shunting away from the gut could be responsible. Therefore, blood flow in the superior mesenteric artery (SMA) and hepatic portal vein (HPV) was examined at sea level (SL) and ...

journal_title：European journal of clinical investigation

authors： Kalson NS,Hext F,Davies AJ,Chan CW,Wright AD,Imray CH,Birmingham Medical Research Expeditionary Society.

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Portal endotoxaemia has been speculated to be crucially involved in the pathogenesis of chronic hepatic inflammation, which is highly associated with the development of type 2 diabetes mellitus. This study tests whether portal endotoxaemia is a pathogenic link between chronic subacute hepatic inflammation an...

journal_title：European journal of clinical investigation

authors： Hsieh PS,Chan JY,Shyu JF,Chen YT,Loh CH

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnoea (OSA) is a common complication of obesity and can have a substantial negative impact on a patient's quality of life and risk of cardiovascular disease. The aim of this case-control study was to undertake discovery profiling of urinary peptides using capillary electrophoresis-mass spe...

journal_title：European journal of clinical investigation

authors： Seetho IW,Siwy J,Albalat A,Mullen W,Mischak H,Parker RJ,Craig S,Duffy N,Hardy KJ,Burniston JG,Wilding JP

更新日期：2014-11-01 00:00:00

abstract：:The formation of metabolites of arachidonic acid by the cyclo-oxygenase and lipoxygenase pathways were determined in human lung tissue, obtained from surgery. In this measurement the chopped tissue was incubated with the calcium ionophore A23187. Formation of metabolites from [1-14C] arachidonic acid was also determin...

journal_title：European journal of clinical investigation

authors： Zijlstra FJ,Naaktgeboren M,Mons H,Vincent JE

更新日期：1987-08-01 00:00:00

abstract：:Time-dependent effects of insulin on the leg exchange of glucose, lactate, glycerol, free fatty acids (FFA) and amino acids were measured in relation to oxygen uptake (leg and whole body) and whole body glucose assimilation including oxidation. Seven healthy males (58 +/- 3 years of age) were investigated before opera...

journal_title：European journal of clinical investigation

authors： Lundgren F,Edén E,Arfvidsson B,Lundholm K

更新日期：1991-08-01 00:00:00

abstract：:Increased activity of the Na+/H+ antiport may be a major abnormality in essential hypertension. The activity of this transport system was investigated in lymphocytes from 13 patients with untreated essential hypertension (Ht) and 13 normotensive control subjects (Nt) on an ad libitum (130-170 mmol d-1) NaCl intake. Fu...

journal_title：European journal of clinical investigation

authors： Göbel BO,Hoffmann G,Ruppert M,Stumpe KO,Vetter H,Siffert W,Düsing R

更新日期：1994-08-01 00:00:00

abstract：:The electrical parameters and the unidirectional fluxes of 45Ca and 3H-mannitol were measured in preparations of rat colon descendens freed from the muscularis externa and mounted in a modified Ussing-chamber. Two criteria were used to differentiate between changes in the trans- and the paracellular calcium transport ...

journal_title：European journal of clinical investigation

authors： Karbach U,Rummel W

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the effect of alpha-lipoic acid (ALA) treatment on endothelium-dependent and -independent vasodilatation, assessed by forearm blood flow (FBF), in patients with type 2 diabetes mellitus. RESEARCH DESIGN AND METHODS:A total of 30 subjects with type 2 diabetes were incl...

journal_title：European journal of clinical investigation

authors： Heinisch BB,Francesconi M,Mittermayer F,Schaller G,Gouya G,Wolzt M,Pleiner J

更新日期：2010-02-01 00:00:00

abstract：:The change in bone mass during 1 1/2 years was determined in a longitudinal study of sixty adult insulin-treated diabetic out-patients. During the study period the mean bone mass decreased by 1.30 +/- 0.28 (SEM)% (P less than 0.001), to a mean value of 91.0 +/- 1.7% of normal (P less than 0.001). The rate of bone loss...

journal_title：European journal of clinical investigation

authors： McNair P,Christiansen C,Christensen MS,Madsbad S,Faber OK,Binder C,Transbøl I

更新日期：1981-02-01 00:00:00

abstract：:Microdialysis was used to selectively assess the effect of the paracrine renin-angiotensin system (RAS) on interstitial glucose and lactate concentration profiles in skeletal muscle of healthy volunteers (n = 8) during basal and insulin-stimulated conditions. Paracrine RAS was selectively inhibited by local retrodialy...

journal_title：European journal of clinical investigation

authors： Müller M,Fasching P,Schmid R,Burgdorff T,Waldhäusl W,Eichler HG

更新日期：1997-10-01 00:00:00

abstract：:The clinical and physiological relevance of the relationship between gastrin and calcitonin has been investigated in normal subjects and in patients suffering from gastritis or duodenal ulcer. Basal plasma levels of calcitonin are increased in these patients but there is no significant relationship between calcitonin ...

journal_title：European journal of clinical investigation

authors： Heynen G,Brassine A,Daubresse JC,Ligny G,Kanis JA,Gaspar S,Franchimont P

更新日期：1981-08-01 00:00:00