Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.

abstract：:The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-l...

journal_title：Scientific reports

authors： Coluccelli N,Cassinerio M,Gambetta A,Laporta P,Galzerano G

更新日期：2015-11-09 00:00:00

abstract：:In this work, disordered-IrMn3/insulating-Y3Fe5O12 exchange-biased bilayers are studied. The behavior of the net magnetic moment ΔmAFM in the antiferromagnet is directly probed by anomalous and planar Hall effects, and anisotropic magnetoresistance. The ΔmAFM is proved to come from the interfacial uncompensated magnet...

journal_title：Scientific reports

authors： Zhou X,Ma L,Shi Z,Fan WJ,Evans RF,Zheng JG,Chantrell RW,Mangin S,Zhang HW,Zhou SM

更新日期：2015-03-17 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Cánovas D,Studt L,Marcos AT,Strauss J

更新日期：2020-03-06 00:00:00

abstract：:Endoconidiophora resinifera (=Ceratocystis resinifera) is a blue-stain fungus that occurs on conifers. The data showed that the Endoconidiophora resinifera mitochondrial genome is one of the largest mitochondrial genomes (>220 kb) so far reported among members of the Ascomycota. An exceptional large number of introns ...

journal_title：Scientific reports

authors： Zubaer A,Wai A,Hausner G

更新日期：2018-12-04 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play diverse roles in biological processes. Aedes aegypti (Ae. aegypti), a blood-sucking mosquito, is the principal vector responsible for replication and transmission of arboviruses including dengue, Zika, and Chikungunya virus. Systematic identification and developmental characterisatio...

journal_title：Scientific reports

authors： Azlan A,Obeidat SM,Yunus MA,Azzam G

更新日期：2019-08-21 00:00:00

abstract：:Artificial sheet materials, known as MetaSurfaces, have been applied to fully control both space and surface waves due to their exceptional abilities to dynamically tailor wave fronts and polarization states, while maintaining small footprints. However, previous and current designs and manufactured MetaSurfaces are li...

journal_title：Scientific reports

authors： La Spada L,Spooner C,Haq S,Hao Y

更新日期：2019-02-28 00:00:00

abstract：:Core-shell nanoparticles often exhibit improved catalytic properties due to the lattice strain created in these core-shell particles. Herein, we demonstrate the synthesis of core-shell Au@Pd nanoparticles from their core-shell Au@Ag/Pd parents. This strategy begins with the preparation of core-shell Au@Ag nanoparticle...

journal_title：Scientific reports

authors： Chen D,Li C,Liu H,Ye F,Yang J

更新日期：2015-07-06 00:00:00

abstract：:Polyphenol oxidases (PPOs) contain the structurally similar enzymes tyrosinases (TYRs) and catechol oxidases (COs). Two cDNAs encoding pro-PPOs from tomato (Solanum lycopersicum) were cloned and heterologously expressed in Escherichia coli. The two pro-PPOs (SlPPO1-2) differ remarkably in their activity as SlPPO1 reac...

journal_title：Scientific reports

authors： Kampatsikas I,Bijelic A,Rompel A

更新日期：2019-03-11 00:00:00

abstract：:Interaction between polycyclic aromatic hydrocarbon (PAH) molecule and energetic ion is a subject of interest in different areas of modern physics. Here, we present measurements of energy and angular distributions of absolute double differential electron emission cross section for coronene (C24H12) and fluorene (C13H1...

journal_title：Scientific reports

authors： Biswas S,Champion C,Weck PF,Tribedi LC

更新日期：2017-07-17 00:00:00

abstract：:We report on the fabrication of spherical Au spheres by pulsed laser treatment using a KrF excimer laser (248 nm, 25 ns) under ambient conditions as a fast and high throughput fabrication technique. The presented experiments were realized using initial Au layers of 100 nm thickness deposited on optically transparent a...

journal_title：Scientific reports

authors： Schmidl G,Jia G,Gawlik A,Kreusch J,Schmidl F,Dellith J,Dathe A,Lin ZH,Huang JS,Plentz J

更新日期：2018-07-26 00:00:00

abstract：:Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke. The aim of the present study was to investigate the efficacy of an optimized IGF-I variant by adding a 40 kDa poly...

journal_title：Scientific reports

authors： Parker K,Berretta A,Saenger S,Sivaramakrishnan M,Shirley SA,Metzger F,Clarkson AN

更新日期：2017-03-21 00:00:00

abstract：:Despite extensive research on primate cognitive function, understanding how anatomical connectivity at a neural circuit level relates to information transformation across different cortical areas remains primitive. New technology is needed to visualize inter-areal anatomical connectivity in living monkeys and to tie t...

journal_title：Scientific reports

authors： Nakamichi Y,Okubo K,Sato T,Hashimoto M,Tanifuji M

更新日期：2019-04-23 00:00:00

abstract：:Salivary duct carcinoma (SDC) is an uncommon, but aggressive malignant tumor with a high mortality rate. Herein, we reported the detection of somatic KRAS A146T and Q61H mutations in 2 out of 4 (50%) sarcomatoid SDC variants. Transgenic mice carrying the human oncogenic KRAS(G12V), which spatiotemporal activation by t...

journal_title：Scientific reports

authors： Fu Y,Cruz-Monserrate Z,Helen Lin H,Chung Y,Ji B,Lin SM,Vonderfecht S,Logsdon CD,Li CF,Ann DK

更新日期：2015-08-20 00:00:00

abstract：:High-resolution microscopy is a valuable tool for studying cellular processes, such as signalling, membrane trafficking, or cytoskeleton remodelling. Several techniques of inclined illumination microscopy allow imaging at a near single molecular level; however, the application of these methods to plant cells is limite...

journal_title：Scientific reports

authors： Kozgunova E,Goshima G

更新日期：2019-10-23 00:00:00

abstract：:Barley is a kind of cereal grass belonging to the family Poaceae. To examine viruses infecting winter barley in Korea, we carried out a comprehensive study of barley RNA viromes using next-generation sequencing (NGS). A total of 110 barley leaf samples from 17 geographical locations were collected. NGS followed by ext...

journal_title：Scientific reports

authors： Jo Y,Bae JY,Kim SM,Choi H,Lee BC,Cho WK

更新日期：2018-09-05 00:00:00

abstract：:The structural, electronic, transport and optical properties of black phosphorus/MoS2 (BP/MoS2) van der Waals (vdw) heterostructure are investigated by using first principles calculations. The band gap of BP/MoS2 bilayer decreases with the applied normal compressive strain and a semiconductor-to-metal transition is ob...

journal_title：Scientific reports

authors： Huang L,Li Y,Wei Z,Li J

更新日期：2015-11-10 00:00:00

abstract：:Acute chest syndrome (ACS) is a major complication of sickle cell anaemia (SCA) and a leading cause for hospital admissions and death. We aimed to study the spectrum of clinical and laboratory features of ACS and to assess the predisposing factors and predictors of severity. A retrospective case-control cohort was stu...

journal_title：Scientific reports

authors： Alkindi S,Al-Busaidi I,Al-Salami B,Raniga S,Pathare A,Ballas SK

更新日期：2020-02-12 00:00:00

abstract：:Development of new antimicrobial agents is required against the causative agent for listeriosis, Listeria monocytogenes, as the number of drug resistant strains continues to increase. A promising target is the β-ketoacyl-acyl carrier protein synthase FabF, which participates in the catalysis of fatty acid synthesis an...

journal_title：Scientific reports

authors： Soares da Costa TP,Nanson JD,Forwood JK

更新日期：2017-01-03 00:00:00

abstract：:Poor oral health is not only associated with diabetes and cardiovascular disease but adverse pregnancy outcomes. However the influence of dental caries on pregnancy is unknown. The aim of this study was to evaluate the association between dental caries and adverse pregnancy outcomes and the effect of treatment for den...

journal_title：Scientific reports

authors： Cho GJ,Kim SY,Lee HC,Kim HY,Lee KM,Han SW,Oh MJ

更新日期：2020-03-24 00:00:00

abstract：:An important step in oxide photochemistry, the loading of electrons into shallow trap states, was studied using infrared (IR) spectroscopy on both, rutile TiO2 powders and single-crystal, r-TiO2(110) oriented samples. After UV-irradiation or n-doping by exposure to H-atoms broad IR absorption lines are observed for th...

journal_title：Scientific reports

authors： Sezen H,Buchholz M,Nefedov A,Natzeck C,Heissler S,Di Valentin C,Wöll C

更新日期：2014-01-22 00:00:00

abstract：:Insulin signaling governs many processes including glucose homeostasis and metabolism, and is therapeutically used to treat hyperglycemia in diabetes. We demonstrated that insulin-induced Akt activation enhances the sensitivity to TGF-β by directing an increase in cell surface TGF-β receptors from a pool of intracellu...

journal_title：Scientific reports

authors： Budi EH,Hoffman S,Gao S,Zhang YE,Derynck R

更新日期：2019-11-18 00:00:00

abstract：:α-Ketoglutarate (αKG) is a metabolite of the tricarboxylic acid cycle, important for biomass synthesis and a precursor for biotechnological products like 1,4-butanediol. In the eukaryote Saccharomyces cerevisiae αKG is present in different compartments. Compartmentation and (intra-)cellular transport could interfere w...

journal_title：Scientific reports

authors： Zhang J,van den Herik BM,Wahl SA

更新日期：2020-07-30 00:00:00

abstract：:Worldwide, prostate cancer (PCa) is the second most common malignancy in males. We undertook a meta-analysis to compare the efficacy and safety of conventional laparoscopic radical prostatectomy with a transperitoneal (TLRP) approach, versus that of an extraperitoneal (ELRP) approach, for treatment of localized PCa. A...

journal_title：Scientific reports

authors： De Hong C,Liang Ren L,Qiang W,Jia W,Ying Chun H,Lu Y,Zheng Hua L,Heng Ping L,Shi Bing Y,Yun Xiang L

更新日期：2015-10-13 00:00:00

abstract：:Biofilm is recognized as a contributing factor to the capacity of Acinetobacter baumannii to persist and prosper in medical settings, but it is still unknown whether biofilms contribute to the spread of A. baumannii. In this study, the biofilm formation of 114 clinical A. baumannii isolates and 32 non-baumannii Acinet...

journal_title：Scientific reports

authors： Hu Y,He L,Tao X,Meng F,Zhang J

更新日期：2016-08-25 00:00:00

abstract：:We report the impact of anti-urothelial autoantibody (AUAb) on urinary bladder phenotype in BALB/c mice deficient of the FcγRIIb and PD-1. AUAb was present in serum samples from approximately half of the double-knockout (DKO) mice, as detected by immunofluorescence and immunoblots for urothelial proteins including uro...

journal_title：Scientific reports

authors： Sugino Y,Nishikawa N,Yoshimura K,Kuno S,Hayashi Y,Yoshimura N,Okazaki T,Kanematsu A,Ogawa O

更新日期：2012-01-01 00:00:00

abstract：:Checkpoint kinases are important in cellular surveillance pathways that help cells to cope with DNA damage and protect their genomes. In cycling cells, DNA replication is one of the most sensitive processes and therefore all organisms carefully regulate replication initiation and progression. The checkpoint kinase ATR...

journal_title：Scientific reports

authors： Bøe CA,Håland TW,Boye E,Syljuåsen RG,Grallert B

更新日期：2018-05-02 00:00:00

abstract：:The topical application of lactic acid bacteria (LAB) is recognized as a useful approach to improve skin health. This work aims to characterize by a multidisciplinary approach, the wound healing, anti-inflammatory, anti-pathogens and proteomic effects of six LAB lysates, belonging to the genus Lactobacillus. Our resul...

journal_title：Scientific reports

authors： Brandi J,Cheri S,Manfredi M,Di Carlo C,Vita Vanella V,Federici F,Bombiero E,Bazaj A,Rizzi E,Manna L,Cornaglia G,Marini U,Valenti MT,Marengo E,Cecconi D

更新日期：2020-07-14 00:00:00

abstract：:Orofacial pain impairs a patient's speech, swallowing, eating and interpersonal relations. Thirty-seven patients with a premalignant oral lesion, 124 patients with oral squamous cell carcinoma (OSSC), and 21 patients with a recurrence of OSSC were evaluated for their orofacial pain. The University of California San Fr...

journal_title：Scientific reports

authors： Yang Y,Zhang P,Li W

更新日期：2017-03-16 00:00:00

abstract：:Recently, graphene nanomesh (GNM) has attracted great attentions due to its unique porous structure, abundant active sites, finite band gap and possesses potential applications in the fields of electronics, gas sensor/storage, catalysis, etc. Therefore, diverse GNMs with different physical and chemical properties are ...

journal_title：Scientific reports

authors： Zhang J,Song H,Zeng D,Wang H,Qin Z,Xu K,Pang A,Xie C

更新日期：2016-08-26 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Whittington CM,O'Meally D,Laird MK,Belov K,Thompson MB,McAllan BM

更新日期：2020-07-22 00:00:00