Abstract:
AIM:Rheumatoid arthritis (RA) is a chronic disease of unknown etiology. Various cellular and molecular immunological factors are involved in the pathophysiology of RA. Recent studies suggest that neutrophils and alpha-defensins released from the neutrophils assume significant roles in the pathogenesis of RA. The aim of this study was to investigate the potential association between serum alpha-defensin levels and disease activity, functional status, radiological damage and several laboratory parameters in patients with RA. MATERIALS AND METHODS:A total of 42 patients with established RA who presented to the outpatient clinics of rheumatology of Dicle University Hospital and 38 healthy control subjects were included in this study. Disease activity was assessed by using the Disease Activity Scale 28 (DAS28). Quality of life was assessed by using the Rheumatoid Arthritis Quality of Life (RAQoL) Questionnaire and the Nottingham Health Profile (NHP). Functional status was assessed by using the Stanford Health Assessment Questionnaire (HAQ). Laboratory examinations included the following tests: CBC, ESH, CRP, and HNP 1-3. RESULTS:Patients with an active disease exhibited higher HNP 1-3 levels compared to patients in remission. At a cut off value of 708 pg/ml, sensitivity and specificity of the tests for HNP 1-3 were 72% and 70.6%, respectively. CONCLUSION:In the present study, patients with an active disease had significantly higher serum HNP 1-3 levels compared to patients in remission. In this respect, serum HNP 1-3 can be a useful marker in the assessment of disease activity and remission in patients with RA.
journal_name
J Back Musculoskelet Rehabiljournal_title
Journal of back and musculoskeletal rehabilitationauthors
Okcu M,Oktayoglu P,Mete N,Bozkurt M,Caglayan M,Dagli AZ,Nas Kdoi
10.3233/BMR-160743subject
Has Abstractpub_date
2018-01-01 00:00:00pages
1145-1150issue
6eissn
1053-8127issn
1878-6324pii
BMR160743journal_volume
31pub_type
杂志文章abstract:BACKGROUND:Systematic reviews have confirmed the effectiveness of work-related rehabilitation with significant cognitive-behavioural components for patients with musculoskeletal disorders (MSDs). In Germany, however, work-related rehabilitation focuses mainly on functional capacity training and less on psychosocial wor...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章,随机对照试验
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更新日期:2011-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Current evidence suggests that lumbosacral transforaminal epidural steroid injection (TFESI) is an effective treatment for lumbosacral radicular pain. However, practitioners may be reluctant to attempt this intervention in obese patients because of a perceived reduction in the chance of provid...
journal_title:Journal of back and musculoskeletal rehabilitation
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journal_title:Journal of back and musculoskeletal rehabilitation
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更新日期:2016-11-21 00:00:00
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journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/BMR-181234
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Many studies report a relationship between poor static posture (SP) and low back pain (LBP). This study examined the effects of a biofeedback postural training program on pre-existing LBP, changes to level of physical activity and workability in participants. OBJECTIVE:To determine if static posture trainin...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-171071
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:Compare the efficacy of orthoses and patient education with and without the addition to Low-Level Laser Therapy (LLLT - 660 nm, 30 mW, a continuous regime and bean area of 0.06 cm2). The laser irradiation was delivered with the fluency of 10J/cm2 in patients with mild and moderate Carpal Tunnel Syndrome (CTS)...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/BMR-150640
更新日期:2016-08-10 00:00:00
abstract::Frozen shoulder is a common disorder characterized by pain and limitation of the glenohumeral joint motions. While it is usually clinically diagnosed, as it can also mimic several other painful shoulder pathologies, imaging techniques can contribute to the differential diagnosis. In the literature, static and dynamic ...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-181448
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Patellofemoral osteoarthritis (PFOA) is associated with pain and decreased self-reported function. The impact of PFOA on actual physical performance is currently unknown. OBJECTIVE:To investigate the impact of PFOA on physical performance and pain. METHODS:Eight participants aged 40-65 years with bilateral...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-140525
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Sensitive muscle strength tests are needed to measure muscle strength in the diagnosis and management of sciatica patients. OBJECTIVE:The aim of this study was to assess the isokinetic muscle strength in sciatica patients' and control subjects' ankles that exhibited normal ankle muscle strength when measure...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-130392
更新日期:2013-01-01 00:00:00
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journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-150621
更新日期:2016-04-27 00:00:00
abstract:BACKGROUND:Diaphragm is an important component of spinal stability. In presence of low back pain, there may be some alterations in this muscle like other muscles that are responsible for lumbal stabilization. OBJECTIVE:This study aims to assess the effects of stabilization exercises on diaphragm muscle thickness and m...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-169749
更新日期:2018-01-01 00:00:00
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journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-2009-0233
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Body height (BH) measurement is an important part of the clinical evaluation of children with idiopathic scoliosis (IS) as its progression is defined based on the observation of a growth spurt. OBJECTIVE:The aim of the study is to assess diurnal variation of BH in children with IS. METHODS:BH was measured ...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-170948
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To compare the short-term effect of prolotherapy and conservative terapy for the Tietze syndrome. PATIENTS AND METHODS:From 2013 to 2014, twenty-one patients underwent prolotherapy (group 1) and thirteen underwent conservative therapy with analgesics (group 2). A visual analogue score (VAS) was recorded for me...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-159269
更新日期:2017-09-22 00:00:00
abstract:OBJECTIVES:This study was conducted to assess the relation between bone mineral density (BMD) and clinic-demographic properties and life quality during postmenopausal period. METHODS:The study group consisted of 172 postmenopausal women who applied to the physical therapy and rehabilitation outpatient clinic at a trai...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-170933
更新日期:2018-01-01 00:00:00
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journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/BMR-170963
更新日期:2018-01-01 00:00:00
abstract::This article deals with the problems associated with the spine in an aging athletic person or in an elderly person who may be interested in starting a sports activity. The anatomy and pathophysiology of the spine as regards aging is discussed, as are common diagnostic tests and physical examination procedures. Specifi...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-1995-5109
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:The aim of this pilot study was to test the generally believed hypothesis that intervertebral disc degeneration is a prerequisite for degenerative spondylolisthesis (DS). METHODS:This cross-sectional study was an ancillary project to the Framingham Study. A sample of 3529 participants aged 40-80 years had a...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-2009-0211
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Osteitis pubis refers to a painful, inflammatory condition involving the pubic bones, pubic symphysis, and adjacent structures. So, the aims of the study were to evaluate the strength of trunk muscles of soccer players suffering from osteitis pubis, and to compare the agonist/antagonist ratio ...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-130429
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Exercises are usually prescribed in association with orthotic intervention for management of idiopathic scoliosis, however the role of these exercises on the efficacy of brace and/or balance is not clear yet. OBJECTIVES:To investigate the role of exercise (the Blount and Moe protocol) on static balance and ...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-181128
更新日期:2019-01-01 00:00:00
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journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-130420
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The core stability theory has emphasized symmetric co-contraction of both anterolateral abdominal muscles (AAM), but there is a lack of research on whether the symmetric co-contraction of AAM is related to the postural stability of the trunk. OBJECTIVE:This study aimed to investigate the correlation between...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-170936
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:There have been a number of recent studies showing the effectiveness of lumbosacral transforaminal steroid epidural injections used in the treatment of radicular pain. The studies include retrospective, prospective and randomized controlled studies. Thus, the data is valuable with regard to identifying evide...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章,评审
doi:10.3233/BMR-2011-0279
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Upper rib manipulative therapy appears to be effective on primary complaint of shoulder pain, but its efficacy has not been evaluated in subjects with whiplash-associated disorders. OBJECTIVE:To assess the immediate changes on neural and muscular mechanosensitivity after first-rib manipulation in patients w...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.3233/BMR-160645
更新日期:2017-01-01 00:00:00
abstract::Rhythmic masticatory muscle activities are probably part of normal jaw motor behavior. Certain factors, like disease, stress, personality, alcohol, and medication, may turn this normal activity into a condition that might include abnormal tooth wear, myofascial pain, and temporomandibular joint problems. This conditio...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-1996-6207
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:The occurrence of specific low back pain (LBP) due to workplace factors has not been well described among kitchen industry workers. This study would claim various risk factors that contributing LBP among kitchen workers. OBJECTIVE:The purpose of the study was to examine the risk factors and the prevalence o...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-140544
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the prerequisite physical features of classical ballet education. METHODS:Students who enrolled and were rejected for the applications of State Conservatory Ballet Main Art Branch in the academic year 2013-2014 and 2014-2015 were compared with their exam results. This s...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-181173
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the effect of primary knee osteoarthritis on the risk of falling. MATERIALS AND METHODS:One hundred participants (50 with knee osteoarthritis and 50 healthy controls) were included in this study. Primary knee osteoarthritis was diagnosed according to the American Col...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-150413
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The Flexi-Bar and Bodyblade are oscillatory tools used in rehabilitation centers worldwide to enhance muscle activity. Because of a lack of reports on the Flexi-Bar, this study focused on erector spinae (ES) muscle activation under different conditions. METHODS:Twelve university students (age 21 ± 2.5 years...
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 临床试验,杂志文章
doi:10.3233/BMR-171011
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The intervertebral disc degeneration changes and paraspinal muscles changes are believed to be risk factors for lumbar degenerative spondylolisthesis (LDS). But there is limited quantitative information about this progression. This study is to reveal their changes the in the progression of LDS....
journal_title:Journal of back and musculoskeletal rehabilitation
pub_type: 杂志文章
doi:10.3233/BMR-140515
更新日期:2015-01-01 00:00:00