Behçet syndrome: effects of Pycnogenol® supplementation during regression phases.

Abstract:

BACKGROUND:The aim of this comparative registry study was to evaluate the supplementation with Pycnogenol® in subjects with Behçet syndrome (BS) with symptoms impairing their quality of life despite being in a remitting phase of the disease. METHODS:Thirty-four patients with a confirmed diagnosis of BS were divided into the control group (without supplement) or the active group, in this specific case using Pycnogenol® (Horphag Research LTD) supplement at the daily dose of 150 mg (50 mg tid) for 4 weeks. RESULTS:All subjects receiving Pycnogenol® reported a significant decrease in symptoms, such as burning/pain due to dryness and ulcerations (P<0.05). In addition, Pycnogenol® showed important anti-inflammatory activity by decreasing ESR, leucocytosis and Pathergy Test response. CONCLUSIONS:Pycnogenol® may be a useful supplementation for the management of BS.

journal_name

Minerva Cardioangiol

authors

Hu S,Belcaro G,Ledda A,Corsi M,Cotellese R,Feragalli B,Hosoi M,Dugall M,Torino-Rodriguez P,Cesarone MR

doi

10.23736/S0026-4725.18.04637-6

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

386-390

issue

4

eissn

0026-4725

issn

1827-1618

pii

S0026-4725.18.04637-6

journal_volume

66

pub_type

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