Abstract:
:With the increase in long-term survival of post-transplant children, there is a paradigm shift in the emphasis of post-transplant care. We describe de novo cardiovascular abnormalities, which occurred in otherwise asymptomatic paediatric liver transplant recipients, who received liver allografts between 1991 and 2014 at the National University Hospital, Singapore, detected during routine post-transplant monitoring. A total of 96 paediatric liver transplants were performed in 90 children. After transplant, 7/90 (7.8%) recipients were identified with new-onset aortopathy. Glycogen storage disease type I (42.9% versus 2.4%; p<0.001) and recipient Epstein-Barr virus seropositivity (85.7 versus 31.0%, p=0.004) were significant risk factors for aortopathy on univariate analysis. On multivariate analysis, only glycogen storage disease type I remained as the significant risk factor (odds ratio 51.3 [95% confidence intervals: 1.1-2498.1, p=0.047]). Liver transplant is a double-edged sword that reverses certain cardiopulmonary complications of end-stage liver disease but may induce de novo structural cardiac injury in the form of aortic dilation.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Huang JG,Lim T,Quek SC,Quak SH,Aw MMdoi
10.1017/S104795111800063Xsubject
Has Abstractpub_date
2018-08-01 00:00:00pages
986-994issue
8eissn
1047-9511issn
1467-1107pii
S104795111800063Xjournal_volume
28pub_type
杂志文章abstract:OBJECTIVE:To examine the clinical utility of the Pediatric Symptom Checklist 17 for identifying psychosocial concerns and improving access to psychology services within a paediatric cardiology clinic. METHOD:Parents of 561 children (aged 4-17 years) presenting for follow-up of CHD, acquired heart disease, or arrhythmi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001900
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Arrhythmias are common in patients admitted to the paediatric intensive care unit. We sought to identify the rates of occurrence and types of arrhythmias, and determine whether an arrhythmia was associated with illness severity and paediatric intensive care unit length of stay. DESIGN:This is a prospective, ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114002339
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:CHD is the leading cause of mortality due to birth defects. Array comparative genomic hybridisation (aCGH) detects submicroscopic copy number changes and may improve identification of the genetic basis of CHD. METHODS:This is a retrospective analysis of 1252 patients from a regional referral centre who had ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114001838
更新日期:2015-08-01 00:00:00
abstract::Isolated aortic regurgitation and myocardial infarction are a rare congenital defect among neonatal patients. We present a case of a neonate with an unusual aortic valve morphology causing both regurgitation and obstruction of the left coronary artery ostium. Despite both non-invasive and invasive imaging modalities, ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001377
更新日期:2020-07-01 00:00:00
abstract::A newborn presented with an aorto-right ventricular tunnel, a defect connecting the left aortic sinus to the right ventricle. The patient underwent repair on 4th day of life. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001572
更新日期:2016-01-01 00:00:00
abstract:UNLABELLED:Physical activity tends to be lower in school-age children with congenital heart disease than in healthy controls. To the best of our knowledge, objectively measured physical activity levels of preschool-age children with congenital heart disease have not been studied. METHODS:A total of 10 children with ei...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114000298
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:In patients with tricuspid atresia palliated by construction of a total cavopulmonary connection, both pulmonary and systemic circulations depend on the performance of the dominant left ventricle. When estimating the volume of such ventricles using cross-sectional echocardiography, it is necessary to make as...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100006521
更新日期:2000-03-01 00:00:00
abstract::Neonatal aortic thrombosis is a rare occurrence but can be life-threatening. Most aortic thrombosis in neonates is related to umbilical artery catheters. A case of a neonate with a spontaneous aortic thrombosis is described here along with a comprehensive review of the literature for cases of neonatal aortic thrombosi...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951119003093
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Post-operative severe vascular stenosis and proliferating endothelial tissue lead to severe circulatory disorders and impair organ perfusion. Bioabsorbable magnesium scaffolds may help to overcome these obstructions without leaving obstructing stent material. We analyse their role in the treatment of vascula...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120000384
更新日期:2020-04-01 00:00:00
abstract::Recently, three-dimensional printing of heart models is being used to plan percutaneous and surgical interventions in patients with CHD. We describe a case where we used a three-dimensional print model to plan a complex percutaneous intervention in a patient with coarctation of the aorta. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116001827
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Tricuspid regurgitation as a manifestation of an isolated congenital anomaly of the tricuspid valve is rare. Cross-sectional and color Doppler echocardiography allow improved evaluation of tricuspid valvar function. As a result, the heterogeneous category of congenital tricuspid valvar dysplasia may be bette...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100004972
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:We describe the structure of, and suggest an etiology for, the interatrial communication which can occur through the mouth of the coronary sinus. Based on the study of human embryos, we propose that the defect is best explained by dissolution of the wall of the coronary sinus adjacent to the left atrium, per...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s104795110001297x
更新日期:2002-07-01 00:00:00
abstract::The persistence of so-called spongy myocardium was first reported in humans in the 1960s. Subsequently, a few reports described the condition, utilizing inconsistent facts and terminology. In 1990 the first report appeared using the term "noncompaction", and detailed its clinical implications. Following this report, m...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951108001972
更新日期:2008-06-01 00:00:00
abstract::The update course in foetal cardiology held by the Fetal Working Group of the Association for European Paediatric and Congenital Cardiology in Istanbul in May 2012 included a session on foetal cardiac therapy. In the introductory overview to this symposium, we critically examine the level of evidence supporting or ref...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951114001231
更新日期:2014-10-01 00:00:00
abstract::Primary care cardiology, also known as ambulatory or outpatient cardiology, for the longitudinal management of patients with common arterial trunk or with transposition of the great arteries is both poorly described and has limited evidence to justify its basis. This article discusses some of the various complications...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951112001588
更新日期:2012-12-01 00:00:00
abstract::We report amiodarone-induced pulmonary toxicity in an 18-year-old boy who had undergone corrective surgery for tetralogy of Fallot 4 years earlier, and was treated with amiodarone because of recurrent malignant postoperative ventricular tachyarrhythmias. Toxicity was recognized on the basis of clinical features, chest...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100008441
更新日期:1999-03-01 00:00:00
abstract::We report the case of a child with cor triatriatum dexter masquerading as Ebstein's anomaly on transthoracic echocardiography. This was attributed to a floppy membrane arising from the right atrium, protruding into the tricuspid valve and pushing the leaflets downwards, giving an impression of Ebstein's anomaly. The i...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111000023
更新日期:2011-06-01 00:00:00
abstract:INTRODUCTION:Exercise echocardiography assesses exercise-induced pulmonary hypertension. The upper normal limit of right ventricular systolic pressure during exercise is not well established. Our study aims to investigate the response of right ventricular systolic pressure in relation to aerobic capacity. METHODS AND ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951109990928
更新日期:2009-09-01 00:00:00
abstract::An 8-year-old girl, without any previous medical history, presented with a first short syncope. Physical examination was unremarkable. Transthoracic echocardiography revealed a thin-walled, echo-free cystic structure adjacent to the posterior wall of the left ventricle, and compressing it moderately. Other echocardiog...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951101001056
更新日期:2001-11-01 00:00:00
abstract::An intact atrial septum places infants with hypoplasia of the left heart into a group with an extremely high rate of mortality. We report a neonate, diagnosed antenatally, who was delivered by Caesarian section in the cardiac theatre, urgently placed onto cardiopulmonary bypass, and who then underwent an atrial septec...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951107000819
更新日期:2007-08-01 00:00:00
abstract::Innocent murmurs are common in childhood. They require accurate diagnosis to avoid unnecessary anxiety and/or restrictions. With this in mind, we studied prospectively children diagnosed by a paediatric cardiologist as having innocent murmurs to review the necessity of investigations in excluding organic abnormalities...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s104795110000963x
更新日期:2000-10-01 00:00:00
abstract::A 10-month-old infant with severe tricuspid valve disease due to staphylococcal bacterial endocarditis, underwent surgical replacement of the valve. The new valve was fashioned using an autologous pericardial patch. Over 3 years of follow-up, the new valve has functioned satisfactorily, with moderately elevated right ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001903
更新日期:2011-08-01 00:00:00
abstract::We present a rare case of incidentally diagnosed Twiddler's syndrome in a child 7 years after implantation of a dual-chamber pacemaker system with epicardial leads. During revision, an insulation defect of the ventricular lead was evident, despite unremarkable prior pacemaker lead testing. The lead was repaired and a ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001031
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:We have used the Amplatzer ductal occluder for transcatheter closure of large persistently patent arterial ducts, and used our experience to assess the safety and efficacy of the device in young children and infants. METHODS AND PATIENTS:We used the Amplatzer ductal occluder prospectively in 43 patients wit...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000570
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:Developmental care of neonates with CHD is essential for proper neurodevelopment. Measurement of developmental care specific to these neonates is needed to ensure consistent implementation within and across cardiac ICUs. The purpose of this study was to psychometrically test the Developmental Care Scale for Neo...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119000337
更新日期:2019-06-01 00:00:00
abstract::Kawasaki disease constitutes an acute febrile vasculitis of unknown aetiology. It is considered the most common cause of acquired cardiac failure in children. Although standard treatment comprises intravenous immunoglobulin and aspirin, some children exhibit refractory disease, necessitating the use of alternative the...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001260
更新日期:2012-08-01 00:00:00
abstract::Congenitally corrected transposition is a rare congenital anomaly, with only a few cases diagnosed and reported prenatally even in the largest fetal series. To determine the morphologic features and outcome for the lesion as recognized during fetal life, we reviewed the fetal and postnatal echocardiograms and medical ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795110400304X
更新日期:2004-06-01 00:00:00
abstract::A bicuspid aortic valve is not only a common congenital heart defect but also an enigmatic condition that can cause a large spectrum of diseases, such as aortic valve stenosis and severe heart failure in newborns whereas aortic dissection in adults. On the contrary, a bicuspid aortic valve can also occur with normal f...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951118001658
更新日期:2019-01-01 00:00:00
abstract::Prematurity and low birth weight adds to the risk of serious congenital heart disease in infants. It may also delay surgical intervention, especially when cardiopulmonary bypass is required, or where an aortopulmonary shunt is necessary to maintain adequate oxygenation. In this setting, neonatologists are faced with t...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112000947
更新日期:2013-06-01 00:00:00
abstract::Supravalvular aortic stenosis is associated with the Williams-Beuren syndrome, but it also occurs in a non-syndromatic congenital form. An elastin gene mutation of chromosome 7q11.23 is responsible in both cases. The vascular features are identical. These patients have a higher risk of sudden death, particularly when ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001563
更新日期:2011-02-01 00:00:00