Non-invasive spinal vibration testing using ultrafast ultrasound imaging: A new way to measure spine function.

Abstract:

:Ultrafast ultrasound imaging is used to capture driven spinal vibrations as a new method for non-invasive spinal testing in living subjects. Previously, it has been shown that accelerometer-based vibration testing in cadaveric models can reveal the presence, location and magnitude of spinal pathology. However, this process remains an invasive procedure as current non-invasive sensors are inadequate. In this paper, the ability of non-invasive ultrafast ultrasound to quantify in vivo vertebral vibration response across a broad range of frequencies (10-100Hz) in anesthetized pig models is investigated. Close agreement with invasive accelerometer measurements is achieved using the non-invasive ultrasound method, opening up unique opportunities to investigate spinal pathologies.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Kaddoura T,Au A,Kawchuk G,Uwiera R,Fox R,Zemp R

doi

10.1038/s41598-018-27816-0

subject

Has Abstract

pub_date

2018-06-25 00:00:00

pages

9611

issue

1

issn

2045-2322

pii

10.1038/s41598-018-27816-0

journal_volume

8

pub_type

杂志文章
  • Antiviral activity of chlorogenic acid against influenza A (H1N1/H3N2) virus and its inhibition of neuraminidase.

    abstract::Lonicera japonica Thunb, rich in chlorogenic acid (CHA), is used for viral upper respiratory tract infection treatment caused by influenza virus, parainfluenza virus, and respiratory syncytial virus, ect in China. It was reported that CHA reduced serum hepatitis B virus level and death rate of influenza virus-infected...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep45723

    authors: Ding Y,Cao Z,Cao L,Ding G,Wang Z,Xiao W

    更新日期:2017-04-10 00:00:00

  • Spatial pattern of plutonium and radiocaesium contamination released during the Fukushima Daiichi nuclear power plant disaster.

    abstract::Plutonium and radiocaesium are hazardous contaminants released by the Fukushima Daiichi nuclear power plant (FDNPP) disaster and their distribution in the environment requires careful characterisation using isotopic information. Comprehensive spatial survey of 134Cs and 137Cs has been conducted on a regular basis sinc...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-34302-0

    authors: Dunne JA,Martin PG,Yamashiki Y,Ang IXY,Scott TB,Richards DA

    更新日期:2018-11-14 00:00:00

  • Coordinated cell motility is regulated by a combination of LKB1 farnesylation and kinase activity.

    abstract::Cell motility requires the precise coordination of cell polarization, lamellipodia formation, adhesion, and force generation. LKB1 is a multi-functional serine/threonine kinase that associates with actin at the cellular leading edge of motile cells and suppresses FAK. We sought to understand how LKB1 coordinates these...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep40929

    authors: Wilkinson S,Hou Y,Zoine JT,Saltz J,Zhang C,Chen Z,Cooper LA,Marcus AI

    更新日期:2017-01-19 00:00:00

  • Early detection and late cognitive control of emotional distraction by the prefrontal cortex.

    abstract::Unpleasant emotional distraction can impair the retention of non-emotional information in working memory (WM). Research links the prefrontal cortex with the successful control of such biologically relevant distractors, although the temporal changes in this brain mechanism remain unexplored. We use magnetoencephalograp...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep10046

    authors: García-Pacios J,Garcés P,Del Río D,Maestú F

    更新日期:2015-06-12 00:00:00

  • Reconstruction of thermotolerant yeast by one-point mutation identified through whole-genome analyses of adaptively-evolved strains.

    abstract::Saccharomyces cerevisiae is used as a host strain in bioproduction, because of its rapid growth, ease of genetic manipulation, and high reducing capacity. However, the heat produced during the fermentation processes inhibits the biological activities and growth of the yeast cells. We performed whole-genome sequencing ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep23157

    authors: Satomura A,Miura N,Kuroda K,Ueda M

    更新日期:2016-03-17 00:00:00

  • Combination of Platelet expression of PKCepsilon and cardiac troponin-I for early diagnosis of chest pain patients in the emergency department.

    abstract::A rapid differential diagnosis of the clinical conditions underlying chest pain is a relevant clinical issue. Specifically, a fast rule-in or -out of acute myocardial infarction (AMI) is mandatory to improve diagnostic outcome and cost-effectiveness of patient management. We demonstrated that Protein Kinase C (PKC) ep...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-38624-5

    authors: Carubbi C,Masselli E,Pozzi G,Mattioli M,Martini S,Goldoni M,Aloe R,Cervellin G,Vitale M,Gobbi G

    更新日期:2019-02-14 00:00:00

  • New Immunosuppressive Sphingoid Base and Ceramide Analogues in Wild Cordyceps.

    abstract::A comprehensive identification of sphingoid bases and ceramides in wild Cordyceps was performed by integrating a sequential chromatographic enrichment procedure and an UHPLC-ultrahigh definition-Q-TOF-MS based sphingolipidomic approach. A total of 43 sphingoid bases and 303 ceramides were identified from wild Cordycep...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep38641

    authors: Mi JN,Han Y,Xu Y,Kou J,Wang JR,Jiang ZH

    更新日期:2016-12-14 00:00:00

  • Formyl peptide receptors promotes neural differentiation in mouse neural stem cells by ROS generation and regulation of PI3K-AKT signaling.

    abstract::This study aimed to determine whether formyl peptide receptors (FPRs) regulated the differentiation of neural stem cells (NSCs). FPRs promote the migration of NSCs both in vitro and in vivo. However, the role of FPRs during differentiation of NSCs is unknown. Analysis by Western blot showed significantly increased exp...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00314-5

    authors: Zhang L,Wang G,Chen X,Xue X,Guo Q,Liu M,Zhao J

    更新日期:2017-03-16 00:00:00

  • Double dissociation of neural responses supporting perceptual and cognitive components of social cognition: evidence from processing of others' pain.

    abstract::Models on how perceptual and cognitive information on others' mental states are treated by the cognitive architecture are often framed as duplex models considering two independent systems. In the context of the neuroscience of empathy analogous systems have been described. Using event-related potentials (i.e., ERPs) t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07424

    authors: Sessa P,Meconi F,Han S

    更新日期:2014-12-11 00:00:00

  • Novel multiarm polyethylene glycol-dihydroartemisinin conjugates enhancing therapeutic efficacy in non-small-cell lung cancer.

    abstract::The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05871

    authors: Dai L,Wang L,Deng L,Liu J,Lei J,Li D,He J

    更新日期:2014-07-29 00:00:00

  • Neutrophil-lymphocyte Ratio Plus Prognostic Nutritional Index Predicts the Outcomes of Patients with Unresectable Hepatocellular Carcinoma After Transarterial Chemoembolization.

    abstract::For many malignancies, inflammation-based scores correlate with survival. The neutrophil-to-lymphocyte ratio (NLR) and prognostic nutritional index (PNI) are immunonutritional indices associated with postoperative outcomes in patients with hepatocellular carcinoma (HCC). We evaluated whether a combined preoperative NL...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13239-w

    authors: Liu C,Li L,Lu WS,Du H,Yan LN,Yang JY,Wen TF,Zeng GJ,Jiang L,Yang J

    更新日期:2017-10-24 00:00:00

  • CR-LAAO, an L-amino acid oxidase from Calloselasma rhodostoma venom, as a potential tool for developing novel immunotherapeutic strategies against cancer.

    abstract::L-amino acid oxidases from snake venoms have been described to possess various biological functions. In this study, we investigated the inflammatory responses induced in vivo and in vitro by CR-LAAO, an L-amino acid oxidase isolated from Calloselasma rhodostoma venom, and its antitumor potential. CR-LAAO induced acute...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42673

    authors: Costa TR,Menaldo DL,Zoccal KF,Burin SM,Aissa AF,Castro FA,Faccioli LH,Greggi Antunes LM,Sampaio SV

    更新日期:2017-02-16 00:00:00

  • Microstructure analysis and mechanical properties of phosphorus-reinforced ZCuPb20Sn5 alloy.

    abstract::An investigation was carried out to assess the effect of the P content on the microstructure and mechanical properties of ZCuPb20Sn5 alloy. Alloys of various compositions, (0.05, 0.1, 0.2, 0.3, 0.5% wt.% P) were melted in a melting furnace under 1200 °C and cast into metal mould, the hardness, strength and elongation ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-49441-1

    authors: Ren XY,Zhang X,Hong X,Ren J

    更新日期:2019-09-16 00:00:00

  • ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis.

    abstract::Several large-scale genome-wide association studies have identified single-nucleotide polymorphisms in the genomic region of A Disintegrin And Metalloproteinase with ThromboSpondin type 1 repeats (ADAMTS)-7 and associations to coronary artery disease. Experimental studies have provided evidence for a functional role o...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/s41598-017-03573-4

    authors: Bengtsson E,Hultman K,Dunér P,Asciutto G,Almgren P,Orho-Melander M,Melander O,Nilsson J,Hultgårdh-Nilsson A,Gonçalves I

    更新日期:2017-06-16 00:00:00

  • Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV).

    abstract::IFI16 and AIM2 are important DNA sensors in antiviral immunity. To characterize these two molecules in a woodchuck model, which is widely used to study hepatitis B virus (HBV) infection, we cloned and analyzed the complete coding sequences (CDSs) of woodchuck IFI16 and AIM2, and found that AIM2 was highly conserved in...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28776

    authors: Yan Q,Li M,Liu Q,Li F,Zhu B,Wang J,Lu Y,Liu J,Wu J,Zheng X,Lu M,Wang B,Yang D

    更新日期:2016-06-29 00:00:00

  • High-energy, Long-cycle-life Secondary Battery with Electrochemically Pre-doped Silicon Anode.

    abstract::Electrochemical pre-doping of a silicon electrode was investigated to create a new class of rechargeable battery with higher energy density. The electrochemical reaction during pre-doping formed a high-quality solid electrolyte interface (SEI) on the surface of silicon particles, which improved the charge and discharg...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59913-4

    authors: Wang Y,Satoh M,Arao M,Matsumoto M,Imai H,Nishihara H

    更新日期:2020-02-21 00:00:00

  • Estimation of High-Speed Liquid-Jet Velocity Using a Pyro Jet Injector.

    abstract::The high-speed liquid-jet velocity achieved using an injector strongly depends on the piston motion, physical property of the liquid, and container shape of the injector. Herein, we investigate the liquid ejection mechanism and a technique for estimating the ejection velocity of a high-speed liquid jet using a pyro je...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56511-x

    authors: Takagaki N,Kitaguchi T,Iwayama M,Shinoda A,Kumamaru H,Honda I

    更新日期:2019-12-27 00:00:00

  • Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo.

    abstract::Synapses are an early pathological target in many neurodegenerative diseases ranging from well-known adult onset conditions such as Alzheimer and Parkinson disease to neurodegenerative conditions of childhood such as spinal muscular atrophy (SMA) and neuronal ceroid lipofuscinosis (NCLs). However, the reasons why syna...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12603-0

    authors: Llavero Hurtado M,Fuller HR,Wong AMS,Eaton SL,Gillingwater TH,Pennetta G,Cooper JD,Wishart TM

    更新日期:2017-09-29 00:00:00

  • Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013-2015.

    abstract::Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013-2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. Nucleotide homologies ranged ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-06987-2

    authors: Feng K,Wang F,Xue Y,Zhou Q,Chen F,Bi Y,Xie Q

    更新日期:2017-07-26 00:00:00

  • The duration of the interpregnancy interval in multiparous women and maternal weight gain between pregnancies: findings from a UK population-based cohort.

    abstract::Maternal obesity in pregnancy increases the risk of adverse long-term health outcomes in both mother and offspring. A population-based cohort of prospectively collected routine antenatal healthcare data collected between January 2003 and September 2017 at University Hospital Southampton, UK was utilised to investigate...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-45595-0

    authors: Ziauddeen N,Roderick PJ,Macklon NS,Alwan NA

    更新日期:2019-06-24 00:00:00

  • CD31hiEmcnhi Vessels Support New Trabecular Bone Formation at the Frontier Growth Area in the Bone Defect Repair Process.

    abstract::CD31hiEmcnhi vessels were a subtype of vessels in the murine skeletal system, with high levels of platelet and endothelial cell adhesion molecule-1 (PECAM-1/CD31) and endomucin (Emcn). They were reported coupling angiogenesis and osteogenesis during bone development. We investigated the distribution of these vessels i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04150-5

    authors: Wang J,Gao Y,Cheng P,Li D,Jiang H,Ji C,Zhang S,Shen C,Li J,Song Y,Cao T,Wang C,Yang L,Pei G

    更新日期:2017-07-10 00:00:00

  • Towards a reliable assessment of Asian elephant population parameters: the application of photographic spatial capture-recapture sampling in a priority floodplain ecosystem.

    abstract::The hitherto difficult task of reliably estimating populations of wide-ranging megafauna has been enabled by advances in capture-recapture methodology. Here we combine photographic sampling with a Bayesian spatially-explicit capture-recapture (SCR) model to estimate population parameters for the endangered Asian eleph...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44795-y

    authors: Goswami VR,Yadava MK,Vasudev D,Prasad PK,Sharma P,Jathanna D

    更新日期:2019-06-12 00:00:00

  • Ultraviolet shadowing of RNA can cause significant chemical damage in seconds.

    abstract::Chemical purity of RNA samples is important for high-precision studies of RNA folding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing steps of sample preparation can reduce this purity. Here, we report the quantitation of UV-induced damage by using reverse transcription and single-nuc...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep00517

    authors: Kladwang W,Hum J,Das R

    更新日期:2012-01-01 00:00:00

  • DeNeRD: high-throughput detection of neurons for brain-wide analysis with deep learning.

    abstract::Mapping the structure of the mammalian brain at cellular resolution is a challenging task and one that requires capturing key anatomical features at the appropriate level of analysis. Although neuroscientific methods have managed to provide significant insights at the micro and macro level, in order to obtain a whole-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50137-9

    authors: Iqbal A,Sheikh A,Karayannis T

    更新日期:2019-09-25 00:00:00

  • Amplitude concentration in a phase-modulated spectrum due to femtosecond filamentation.

    abstract::We present a method by which the spectral intensity of an ultrafast laser pulse can be accumulated at selected frequencies by a controllable amount. Using a 4-f pulse shaper we modulate the phase of the frequency components of a femtosecond laser. By inducing femtosecond filamentation with the modulated pulse, we can ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep43367

    authors: Thompson JV,Zhokhov PA,Springer MM,Traverso AJ,Yakovlev VV,Zheltikov AM,Sokolov AV,Scully MO

    更新日期:2017-03-07 00:00:00

  • Author Correction: Jawbone microenvironment promotes periodontium regeneration by regulating the function of periodontal ligament stem cells.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-65652-3

    authors: Zhu B,Liu W,Liu Y,Zhao X,Zhang H,Luo Z,Jin Y

    更新日期:2020-05-27 00:00:00

  • Grafting alters tomato transcriptome and enhances tolerance to an airborne virus infection.

    abstract::Grafting of commercial tomato varieties and hybrids on the tomato ecotype Manduria resulted in high levels of tolerance to the infection of Sw5 resistance-breaking strains of tomato spotted wilt virus and of severe cucumber mosaic virus strains supporting hypervirulent satellite RNAs that co-determine stunting and nec...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59421-5

    authors: Spanò R,Ferrara M,Montemurro C,Mulè G,Gallitelli D,Mascia T

    更新日期:2020-02-13 00:00:00

  • Cross-border portfolio investment networks and indicators for financial crises.

    abstract::Cross-border equity and long-term debt securities portfolio investment networks are analysed from 2002 to 2012, covering the 2008 global financial crisis. They serve as network-proxies for measuring the robustness of the global financial system and the interdependence of financial markets, respectively. Two early-warn...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep03991

    authors: Joseph AC,Joseph SE,Chen G

    更新日期:2014-02-10 00:00:00

  • Enhancing the durable performance of LiMn2O4 at high-rate and elevated temperature by nickel-magnesium dual doping.

    abstract::Various nickel and magnesium dual-doped LiNixMg0.08Mn1.92-xO4 (x ≤ 0.15) were synthesized via a modified solid-state combustion method. All as-prepared samples show typical spinel phase with a well-defined polyhedron morphology. The Ni-Mg dual-doping obviously decreases the lattice parameter that gives rise to the lat...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53494-7

    authors: Yu Y,Guo J,Xiang M,Su C,Liu X,Bai H,Bai W,Duan K

    更新日期:2019-11-14 00:00:00

  • Low-Dose Tacrolimus Prevents Dysregulated Peri-Conceptional Ovarian and Systemic Immune Cellular Homeostasis in Subjects with PCOS.

    abstract::Polycystic ovary syndrome (PCOS) is characterized by failure of ovulation and is associated with obesity and chronic inflammation. Recent evidence suggests that anomalous activation of ovarian macrophages and numerical and functional deficits in the Th17 (CD4+IL17A+) and the CD4+CD25+CD127low Tregs plays crucial role ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-42960-x

    authors: Albaghdadi AJH,Feeley CA,Kan FWK

    更新日期:2019-04-25 00:00:00