Abstract:
:A membrane-bound phospholipase C-like hydrolase present in lysates of bloodstream forms of Trypanosoma brucei rapidly converts the membrane form of the variant surface protein to the soluble form and 1,2-dimyristoylglycerol [(1985) M.A.J. Ferguson et al. J. Biol. Chem., 260, 4963-4968]. The hydrolase is inhibited by p-chloromercuribenzenesulfonate. The synthesis of the enzyme is rapidly repressed upon differentiation of bloodstream forms to procyclic cells and the enzyme activity declines to an undetectable level during subsequent growth of procyclic forms.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Bülow R,Overath Pdoi
10.1016/0014-5793(85)81223-0subject
Has Abstractpub_date
1985-07-22 00:00:00pages
105-10issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(85)81223-0journal_volume
187pub_type
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