Abstract:
:The Clarkia lagerstätte (Latah Formation) of Idaho is well known for its beautifully preserved plant fossils as well as a fauna of insects and fish. Here we present the first known tetrapod fossil from these deposits. This specimen, recovered from the lower anoxic zone of the beds, is preserved as a carbonaceous film of a partial skeleton associated with a partial lower incisor and some tooth fragments. The morphology of the teeth indicates that the first tetrapod reported from Clarkia is a rodent. Its skeletal morphology as well as its bunodont and brachydont dentition suggests that it is a member of the squirrel family (Sciuridae). It is a large specimen that cannot be assigned to a known genus. Instead, it appears to represent the first occurrence of a new taxon with particularly gracile postcranial morphology likely indicative of an arboreal ecology. This new specimen is a rare glimpse into the poorly known arboreal mammal fossil record of the Neogene. It supports a greater taxonomic and ecological diversity of Miocene Sciuridae than previously recognized and offers new lines of inquiry in the paleoecological research enabled by the unique preservation conditions of the Clarkia biota.
journal_name
PeerJjournal_title
PeerJauthors
Calede JJM,Orcutt JD,Kehl WA,Richards BDdoi
10.7717/peerj.4880subject
Has Abstractpub_date
2018-06-08 00:00:00pages
e4880issn
2167-8359pii
4880journal_volume
6pub_type
杂志文章相关文献
PeerJ文献大全abstract::A range of diseases is associated with amyloid fibril formation. Despite different proteins being responsible for each disease, all of them share similar features including beta-sheet-rich secondary structure and fibril-like protein aggregates. A number of proteins can form amyloid-like fibrils in vitro, resembling st...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1271
更新日期:2015-09-24 00:00:00
abstract::It is an important issue whether microorganisms can live harmoniously with normal cells in the cardiovascular system. The answer to the question will have enormous impact on medical microbiology. To address the issue, it is essential to identify and characterize the bloodborne microbes in an efficient and comprehensiv...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7426
更新日期:2019-08-06 00:00:00
abstract:BACKGROUND:In previous studies, both 17β-estradiol (E2) and resveratrol (RES) were reported to protect intervertebral disc cells against aberrant apoptosis. Given that E2 has a better anti-apoptotic effect with more cancer risk and RES has an anti-apoptotic effect with less cancer risk, the combined use of E2 with RES ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1640
更新日期:2016-01-26 00:00:00
abstract::The amphibian skin microbiome has been the focus of recent studies aiming to better understand the role of these microbial symbionts in host defense against disease. However, host-associated microbial communities are complex and dynamic, and changes in their composition and structure can influence their function. Unde...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7044
更新日期:2019-06-21 00:00:00
abstract::Prostaglandin E1 (PGE1), known pharmaceutically as alprostadil, has vasodilatory properties and is used widely in various clinical settings. In addition to acute vasodilatory properties, PGE1 may exert beneficial effects by altering protein expression of vascular cells. PGE1 is reported to be a potent stimulator of an...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.220
更新日期:2013-11-28 00:00:00
abstract::Xiphosurans are aquatic chelicerates with a fossil record extending into the Early Ordovician and known from a total of 88 described species, four of which are extant. Known for their apparent morphological conservatism, for which they have gained notoriety as supposed 'living fossils', recent analyses have demonstrat...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10431
更新日期:2020-12-04 00:00:00
abstract:Background:This study evaluates the generalizability of an eight-station progress clinical skills examination and assesses the growth in performance for six clinical skills domains among first- and second-year medical students over four time points during the academic year. Methods:We conducted a generalizability stud...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9091
更新日期:2020-05-01 00:00:00
abstract:Background:WRKY proteins play a vital role in the plants response to different stresses, growth and development. Studies of WRKY proteins have been mainly focused on model plant Arabidopsis and a few other vegetable plants. However, the systematical study of eggplant WRKY transcription factor superfamily is scarce. Me...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8777
更新日期:2020-03-17 00:00:00
abstract::Recent improvements in next-generation sequencing (NGS) technologies can facilitate the obtainment of mitochondrial genomes. However, it is not clear whether NGS could be effectively used to reconstruct the mitogenome with high gene rearrangement. These high rearrangements would cause amplification failure, and/or ass...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2786
更新日期:2016-12-15 00:00:00
abstract::Müller glia in the zebrafish retina respond to retinal damage by re-entering the cell cycle, which generates large numbers of retinal progenitors that ultimately replace the lost neurons. In this study we compared the regenerative outcomes of adult zebrafish exposed to one round of phototoxic treatment with adult zebr...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5646
更新日期:2018-09-20 00:00:00
abstract::The orientation of vascular canals in primary bone may reflect differences in growth rate and/or adaptation to biomechanical loads. Previous studies link specific canal orientations to bone growth rates, but results between different taxa are contradictory. Circumferential vascular canals (forming laminar bone) have b...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7616
更新日期:2019-09-25 00:00:00
abstract:Aim:We aimed to translate and cross-culturally adapt the International Knee Documentation Committee-subjective knee form (IKDC) in Romanian. Method:The original (US) IKDC-subjective knee form was translated according to recommended guidelines. Validity was tested using Spearmans's correlation coefficient between score...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8448
更新日期:2020-02-03 00:00:00
abstract::In this study, we sequenced the genome of Pandoraea pnomenusa RB38 using Pacific Biosciences RSII (PacBio) Single Molecule Real Time (SMRT) sequencing technology. A pair of cognate luxI/R homologs was identified where the luxI homolog, ppnI, was found adjacent to a luxR homolog, ppnR1. An additional orphan luxR homolo...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1225
更新日期:2015-08-27 00:00:00
abstract:BACKGROUND:Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment, since it has been isolated from water, soil or dust. In rec...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2833
更新日期:2017-01-03 00:00:00
abstract:BACKGROUND AND AIMS:Cryptic peracarids are an important component of the coral reef fauna in terms of diversity and abundance, yet they have been poorly studied. The aim of this study was to evaluate the taxonomic richness and abundance of cryptic peracarids in coral rubble in the Puerto Morelos Reef National Park, Mex...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3411
更新日期:2017-06-15 00:00:00
abstract::Accommodation resistance is a training technique that may improve strength and power gains beyond those achieved by traditional free weights. In this method, chains are either added on a free-weight bar and combined with traditional plates or added to the bar as the entire load. Purpose. The aim of the current study w...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.441
更新日期:2014-06-17 00:00:00
abstract:Background:RNA sequencing is an indispensable research tool used in a broad range of transcriptome analysis studies. The most common application of RNA Sequencing is differential expression analysis and it is used to determine genetic loci with distinct expression across different conditions. An emerging field called s...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10469
更新日期:2020-12-22 00:00:00
abstract:Background:Conserving both biodiversity and ecosystem services is a major goal of the Convention on Biological Diversity. Hotspots for biodiversity in the Andes significantly overlap with areas with dense human populations that sustain their economy through agricultural production. Therefore, developing management form...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6207
更新日期:2019-02-13 00:00:00
abstract:Background:The Mountain Pygmy-possum (Burramys parvus) is a critically endangered marsupial, endemic to alpine regions of southern Australia. We investigated the diet of a recently discovered population of the possum in northern Kosciuszko National Park, NSW, Australia. This new population occurs at elevations well bel...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6307
更新日期:2019-01-24 00:00:00
abstract::A prolonged preservation duration of blood specimens at 4 °C may occur due to the distance from collection points to storage facilities in many biobanks, especially for multicenter studies. This could lead to RNA degradation, affecting downstream analyses. However, effects of preservation durations at 4 °C on RNA qual...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8940
更新日期:2020-04-10 00:00:00
abstract::The exploration of the evolution of RNA viruses has been aided recently by the discovery of copies of fragments or complete genomes of non-retroviral RNA viruses (Non-retroviral Endogenous RNA Viral Elements, or NERVEs) in many eukaryotic nuclear genomes. Among the most prominent NERVEs are partial copies of the RNA d...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.876
更新日期:2015-04-09 00:00:00
abstract::Live trapping is a common tool used to assess demography of small mammals. However, live-trapping is often expensive and stressful to captured individuals. Thus, assessing the relative tradeoffs among study goals, project expenses, and animal well-being is necessary. Here, we evaluated how apparent bias and precision ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7783
更新日期:2019-10-03 00:00:00
abstract::Grazing and litter removal can alter understory structure and composition after afforestation, posing a serious threat to sustainable forest development. Enclosure is considered to be an effective measure to restore degraded forest restoration. However, little is known about the dynamics of soil nutrients and microbia...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8857
更新日期:2020-03-25 00:00:00
abstract:Background:The current cultivation and plant breeding of Honeybush tea (produced from members of Cyclopia Vent.) do not consider the genetic diversity nor structuring of wild populations. Thus, wild populations may be at risk of genetic contamination if cultivated plants are grown in the same landscape. Here, we invest...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9818
更新日期:2020-09-02 00:00:00
abstract::We demonstrated that the 3-substituted benzothiophene-1,1-dioxide class of compounds are effective inhibitors of Mycobacterium tuberculosis growth under aerobic conditions. We examined substitution at the C-3 position of the benzothiophene-1,1-dioxide series systematically to delineate structure-activity relationships...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.612
更新日期:2014-10-07 00:00:00
abstract:Background:Fibroblast growth factor 2 (FGF2) is a highly pleiotropic cytokine with antifibrotic activity in wound healing. During the process of wound healing and fibrosis, fibroblasts are the key players. Although accumulating evidence has suggested the antagonistic effects of FGF2 in the activation process of fibrobl...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10671
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Rare or narrowly endemic organisms are difficult to monitor and conserve when their total distribution and habitat preferences are incompletely known. One method employed in determining distributions of these organisms is species distribution modeling (SDM). METHODS:Using two species of narrowly endemic bur...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3632
更新日期:2017-07-31 00:00:00
abstract::Hydrolysis of ATP by Na+/K+-ATPase, a P-Type ATPase, catalyzing active Na+ and K+ transport through cellular membranes leads transiently to a phosphorylation of its catalytical α-subunit. Surprisingly, three-dimensional molecular structure analysis of P-type ATPases reveals that binding of ATP to the N-domain connecte...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3087
更新日期:2017-03-14 00:00:00
abstract:Background:To reduce bird fatalities from millions of window collisions each year in North America, it is important to understand how design and landscape elements relate to collision risk. The current study extends prior research that found that buildings near ornamental pear trees (Prunus calleryana) and buildings wi...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9401
更新日期:2020-06-19 00:00:00
abstract::Relative gene expression data obtained from quantitative RT-PCR (RT-qPCR) experiments are dependent on appropriate normalization to represent true values. It is common to use constitutively expressed endogenous reference genes (RGs) for normalization, but for this strategy to be valid the RGs must be stably expressed ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7181
更新日期:2019-06-26 00:00:00