Spatially confined lignin nanospheres for biocatalytic ester synthesis in aqueous media.

abstract：:Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...

journal_title：Nature communications

authors： Riva A,Kuzyk O,Forsberg E,Siuzdak G,Pfann C,Herbold C,Daims H,Loy A,Warth B,Berry D

更新日期：2019-09-25 00:00:00

abstract：:Recent studies suggest that attention samples space rhythmically through oscillatory interactions in the frontoparietal network. How these attentional fluctuations coincide with spatial exploration/displacement and exploitation/selection by a dynamic attentional spotlight under top-down control is unclear. Here, we sh...

journal_title：Nature communications

authors： Gaillard C,Ben Hadj Hassen S,Di Bello F,Bihan-Poudec Y,VanRullen R,Ben Hamed S

更新日期：2020-02-17 00:00:00

abstract：:Graphene nanoscrolls are Archimedean-type spirals formed by rolling single-layer graphene sheets. Their unique structure makes them conceptually interesting and understanding their formation gives important information on the manipulation and characteristics of various carbon nanostructures. Here we report a 100% effi...

journal_title：Nature communications

authors： Sharifi T,Gracia-Espino E,Barzegar HR,Jia X,Nitze F,Hu G,Nordblad P,Tai CW,Wågberg T

更新日期：2013-01-01 00:00:00

abstract：:Neurons can activate pathways that destroy the whole cell via apoptosis or selectively degenerate only the axon (pruning). Both apoptosis and axon degeneration require Bax and caspases. Here we demonstrate that despite this overlap, the pathways mediating axon degeneration during apoptosis versus axon pruning are dist...

journal_title：Nature communications

authors： Cusack CL,Swahari V,Hampton Henley W,Michael Ramsey J,Deshmukh M

更新日期：2013-01-01 00:00:00

abstract：:5-Fluorouracil (5-FU) remains the first-line treatment for colorectal cancer (CRC). Although 5-FU initially de-bulks the tumor mass, recurrence after chemotherapy is the barrier to effective clinical outcomes for CRC patients. Here, we demonstrate that p53 promotes WNT3 transcription, leading to activation of the WNT/...

journal_title：Nature communications

authors： Cho YH,Ro EJ,Yoon JS,Mizutani T,Kang DW,Park JC,Il Kim T,Clevers H,Choi KY

更新日期：2020-10-21 00:00:00

abstract：:Protein tyrosine phosphatases regulate a myriad of essential subcellular signaling events, yet they remain difficult to study in their native biophysical context. Here we develop a minimally disruptive optical approach to control protein tyrosine phosphatase 1B (PTP1B)-an important regulator of receptor tyrosine kinas...

journal_title：Nature communications

authors： Hongdusit A,Zwart PH,Sankaran B,Fox JM

更新日期：2020-02-07 00:00:00

abstract：:Ecosystems are composed of complex networks of many species interacting in different ways. While ecologists have long studied food webs of feeding interactions, recent studies increasingly focus on mutualistic networks including plants that exchange food for reproductive services provided by animals such as pollinator...

journal_title：Nature communications

authors： Hale KRS,Valdovinos FS,Martinez ND

更新日期：2020-05-01 00:00:00

abstract：:Amyloid supramolecular assemblies have found widespread exploitation as ordered nanomaterials in a range of applications from materials science to biotechnology. New strategies are, however, required for understanding and promoting mature fibril formation from simple monomer motifs through easy and scalable processes....

journal_title：Nature communications

authors： Bertolani A,Pirrie L,Stefan L,Houbenov N,Haataja JS,Catalano L,Terraneo G,Giancane G,Valli L,Milani R,Ikkala O,Resnati G,Metrangolo P

更新日期：2015-06-30 00:00:00

abstract：:Deep learning algorithms have been successfully used in medical image classification. In the next stage, the technology of acquiring explainable knowledge from medical images is highly desired. Here we show that deep learning algorithm enables automated acquisition of explainable features from diagnostic annotation-fr...

journal_title：Nature communications

authors： Yamamoto Y,Tsuzuki T,Akatsuka J,Ueki M,Morikawa H,Numata Y,Takahara T,Tsuyuki T,Tsutsumi K,Nakazawa R,Shimizu A,Maeda I,Tsuchiya S,Kanno H,Kondo Y,Fukumoto M,Tamiya G,Ueda N,Kimura G

更新日期：2019-12-18 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) is a clonal disorder of mature B cells. Most patients are characterised by an indolent disease course and an anergic phenotype of their leukaemia cells, which refers to a state of unresponsiveness to B cell receptor stimulation. Up to 10% of CLL patients transform from an indolent s...

journal_title：Nature communications

authors： Märklin M,Heitmann JS,Fuchs AR,Truckenmüller FM,Gutknecht M,Bugl S,Saur SJ,Lazarus J,Kohlhofer U,Quintanilla-Martinez L,Rammensee HG,Salih HR,Kopp HG,Haap M,Kirschniak A,Kanz L,Rao A,Wirths S,Müller MR

更新日期：2017-10-02 00:00:00

abstract：:The continuum hypothesis states that both deterministic and stochastic processes contribute to the assembly of ecological communities. However, the contextual dependency of these processes remains an open question that imposes strong limitations on predictions of community responses to environmental change. Here we me...

journal_title：Nature communications

authors： Powell JR,Karunaratne S,Campbell CD,Yao H,Robinson L,Singh BK

更新日期：2015-10-05 00:00:00

abstract：:Canonical Wnt signaling is crucial for vascularization of the central nervous system and blood-brain barrier (BBB) formation. BBB formation and modulation are not only important for development, but also relevant for vascular and neurodegenerative diseases. However, there is little understanding of how Wnt signaling c...

journal_title：Nature communications

authors： Hübner K,Cabochette P,Diéguez-Hurtado R,Wiesner C,Wakayama Y,Grassme KS,Hubert M,Guenther S,Belting HG,Affolter M,Adams RH,Vanhollebeke B,Herzog W

更新日期：2018-11-19 00:00:00

abstract：:Photoelectrochemical (PEC) water splitting promises a solution to the problem of large-scale solar energy storage. However, its development has been impeded by the poor performance of photoanodes, particularly in their capability for photovoltage generation. Many examples employing photovoltaic modules to correct the ...

journal_title：Nature communications

authors： Jang JW,Du C,Ye Y,Lin Y,Yao X,Thorne J,Liu E,McMahon G,Zhu J,Javey A,Guo J,Wang D

更新日期：2015-06-16 00:00:00

abstract：:Adaptive behavior requires integrating prior with current information to anticipate upcoming events. Brain structures related to this computation should bring relevant signals from the recent past into the present. Here we report that rats can integrate the most recent prior information with sensory information, there...

journal_title：Nature communications

authors： Nogueira R,Abolafia JM,Drugowitsch J,Balaguer-Ballester E,Sanchez-Vives MV,Moreno-Bote R

更新日期：2017-03-24 00:00:00

abstract：:Generally, a homogeneous catalyst exhibits good activity and defined active sites but it is difficult to recycle. Meanwhile, a heterogeneous catalyst can easily be reused but its active site is difficult to reveal. It is interesting to bridge the gap between homogeneous and heterogeneous catalysis via controllable con...

journal_title：Nature communications

authors： Zhang Y,Pang S,Wei Z,Jiao H,Dai X,Wang H,Shi F

更新日期：2018-04-13 00:00:00

abstract：:Tenuazonic acid (TeA) is a well-known mycotoxin produced by various plant pathogenic fungi. However, its biosynthetic gene has been unknown to date. Here we identify the TeA biosynthetic gene from Magnaporthe oryzae by finding two TeA-inducing conditions of a low-producing strain. We demonstrate that TeA is synthesize...

journal_title：Nature communications

authors： Yun CS,Motoyama T,Osada H

更新日期：2015-10-27 00:00:00

abstract：:The force generated by the actomyosin cytoskeleton controls focal adhesion dynamics during cell migration. This process is thought to involve the mechanical unfolding of talin to expose cryptic vinculin-binding sites. However, the ability of the actomyosin cytoskeleton to directly control the formation of a talin-vinc...

journal_title：Nature communications

authors： Ciobanasu C,Faivre B,Le Clainche C

更新日期：2014-01-01 00:00:00

abstract：:Chemical modifications on DNA molecules, such as 5-methylcytosine and 5-hydroxymethylcytosine, play important roles in the mammalian brain. A novel DNA adenine modification, N(6)-methyladenine (6mA), has recently been found in mammalian cells. However, the presence and function(s) of 6mA in the mammalian brain remain ...

journal_title：Nature communications

authors： Yao B,Cheng Y,Wang Z,Li Y,Chen L,Huang L,Zhang W,Chen D,Wu H,Tang B,Jin P

更新日期：2017-10-24 00:00:00

abstract：:Symbiotic associations occur in every habitat on earth, but we know very little about their evolutionary histories. Current models of trait evolution cannot adequately reconstruct the deep history of symbiotic innovation, because they assume homogenous evolutionary processes across millions of years. Here we use a rec...

journal_title：Nature communications

authors： Werner GD,Cornwell WK,Sprent JI,Kattge J,Kiers ET

更新日期：2014-06-10 00:00:00

abstract：:Imaging compound action potentials (CAPs) in peripheral nerves could help avoid side effects in neuromodulation by selective stimulation of identified fascicles. Existing methods have low resolution, limited imaging depth, or are invasive. Fast neural electrical impedance tomography (EIT) allows fascicular CAP imaging...

journal_title：Nature communications

authors： Ravagli E,Mastitskaya S,Thompson N,Iacoviello F,Shearing PR,Perkins J,Gourine AV,Aristovich K,Holder D

更新日期：2020-12-07 00:00:00

abstract：:Centromeres consist of specialized centrochromatin containing CENP-A nucleosomes intermingled with H3 nucleosomes carrying transcription-associated modifications. We have designed a novel synthetic biology 'in situ epistasis' analysis in which H3 dimethylated on lysine 4 (H3K4me2) demethylase LSD2 plus synthetic modul...

journal_title：Nature communications

authors： Molina O,Vargiu G,Abad MA,Zhiteneva A,Jeyaprakash AA,Masumoto H,Kouprina N,Larionov V,Earnshaw WC

更新日期：2016-11-14 00:00:00

abstract：:Imaging the optical properties of individual nanosystems beyond fluorescence can provide a wealth of information. However, the minute signals for absorption and dispersion are challenging to observe, and only specialized techniques requiring sophisticated noise rejection are available. Here we use signal enhancement i...

journal_title：Nature communications

authors： Mader M,Reichel J,Hänsch TW,Hunger D

更新日期：2015-06-24 00:00:00

abstract：:Adult neural stem cells reside in a specialized niche in the subventricular zone (SVZ). Throughout life they give rise to adult-born neurons in the olfactory bulb (OB), thus contributing to neural plasticity and pattern discrimination. Here, we show that the neurovascular protein EGFL7 is secreted by endothelial cells...

journal_title：Nature communications

authors： Bicker F,Vasic V,Horta G,Ortega F,Nolte H,Kavyanifar A,Keller S,Stankovic ND,Harter PN,Benedito R,Lutz B,Bäuerle T,Hartwig J,Baumgart J,Krüger M,Radyushkin K,Alberi L,Berninger B,Schmidt MHH

更新日期：2017-06-28 00:00:00

abstract：:Akt2 and its downstream effectors mediate insulin-stimulated GLUT4-storage vesicle (GSV) translocation and fusion with the plasma membrane (PM). Using mass spectrometry, we identify actin-capping protein Tropomodulin 3 (Tmod3) as an Akt2-interacting partner in 3T3-L1 adipocytes. We demonstrate that Tmod3 is phosphoryl...

journal_title：Nature communications

authors： Lim CY,Bi X,Wu D,Kim JB,Gunning PW,Hong W,Han W

更新日期：2015-01-09 00:00:00

abstract：:The original version of this Article was missing the ORCID ID of Professor Nicola Pugno.Also in the original version of this Article, the third to last sentence of the fourth paragraph of the Results incorrectly read 'However, the stepwise addition of CNTs increases the self-entanglement and thereby the compressive st...

journal_title：Nature communications

authors： Schütt F,Signetti S,Krüger H,Röder S,Smazna D,Kaps S,Gorb SN,Mishra YK,Pugno NM,Adelung R

更新日期：2018-01-09 00:00:00

abstract：:Affiliation 4 incorrectly read 'University of the Basque Country (Ikerbasque), University of the Basque Country and Donostia International Physics Center, San Sebastian 20018, Spain.'Also, the affiliations of Ignacio Arganda-Carreras with 'IKERBASQUE, Basque Foundation for Science, Bilbao, 48013, Spain' and 'Donostia ...

journal_title：Nature communications

authors： Abdeladim L,Matho KS,Clavreul S,Mahou P,Sintes JM,Solinas X,Arganda-Carreras I,Turney SG,Lichtman JW,Chessel A,Bemelmans AP,Loulier K,Supatto W,Livet J,Beaurepaire E

更新日期：2019-05-09 00:00:00

abstract：:Marine coastal ecosystems are among the most exposed to global environmental change, with reported effects on species biomass, species richness and length of trophic chains. By combining a biologically informed food-web model with information on anthropogenic influences in 701 sites across the Caribbean region, we sho...

journal_title：Nature communications

authors： Gilarranz LJ,Mora C,Bascompte J

更新日期：2016-02-12 00:00:00

abstract：:Since the formulation of the geometric phase by Berry, its relevance has been demonstrated in a large variety of physical systems. However, a geometric phase of the most fundamental spin-1/2 system, the electron spin, has not been observed directly and controlled independently from dynamical phases. Here we report exp...

journal_title：Nature communications

authors： Nagasawa F,Frustaglia D,Saarikoski H,Richter K,Nitta J

更新日期：2013-01-01 00:00:00

abstract：:Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to the difficulty of their detection. Here, we develop a new high-throughput genotyping method based...

journal_title：Nature communications

authors： Giner-Delgado C,Villatoro S,Lerga-Jaso J,Gayà-Vidal M,Oliva M,Castellano D,Pantano L,Bitarello BD,Izquierdo D,Noguera I,Olalde I,Delprat A,Blancher A,Lalueza-Fox C,Esko T,O'Reilly PF,Andrés AM,Ferretti L,Puig M,Cáce

更新日期：2019-09-17 00:00:00

abstract：:Angiogenesis is essential for tissue development, wound healing and tissue perfusion, with its dysregulation linked to tumorigenesis, rheumatoid arthritis and heart disease. Here we show that pro-angiogenic stimuli couple to NADPH oxidase-dependent generation of oxidants that catalyse an activating intermolecular-disu...

journal_title：Nature communications

authors： Burgoyne JR,Rudyk O,Cho HJ,Prysyazhna O,Hathaway N,Weeks A,Evans R,Ng T,Schröder K,Brandes RP,Shah AM,Eaton P

更新日期：2015-08-10 00:00:00