当前位置： SCI文献检索 > JAMA Neurology期刊下所有文献 > Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders.

Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders.

Abstract：

Importance:Functional neurological disorders (FND) are common sources of disability in medicine. Patients have often been misdiagnosed, correctly diagnosed after lengthy delays, and/or subjected to poorly delivered diagnoses that prevent diagnostic understanding and lead to inappropriate treatments, iatrogenic harm, unnecessary and costly evaluations, and poor outcomes. Observations:Functional Neurological Symptom Disorder/Conversion Disorder was adopted by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, replacing the term psychogenic with functional and removing the criterion of psychological stress as a prerequisite for FND. A diagnosis can now be made in an inclusionary manner by identifying neurological signs that are specific to FNDs without reliance on presence or absence of psychological stressors or suggestive historical clues. The new model highlights a wider range of past sensitizing events, such as physical trauma, medical illness, or physiological/psychophysiological events. In this model, strong ideas and expectations about these events correlate with abnormal predictions of sensory data and body-focused attention. Neurobiological abnormalities include hypoactivation of the supplementary motor area and relative disconnection with areas that select or inhibit movements and are associated with a sense of agency. Promising evidence has accumulated for the benefit of specific physical rehabilitation and psychological interventions alone or in combination, but clinical trial evidence remains limited. Conclusions and Relevance:Functional neurological disorders are a neglected but potentially reversible source of disability. Further research is needed to determine the dose and duration of various interventions, the value of combination treatments and multidisciplinary therapy, and the therapeutic modality best suited for each patient.

journal_name

JAMA Neurol

journal_title

JAMA neurology

authors

Espay AJ,Aybek S,Carson A,Edwards MJ,Goldstein LH,Hallett M,LaFaver K,LaFrance WC Jr,Lang AE,Nicholson T,Nielsen G,Reuber M,Voon V,Stone J,Morgante F

doi

10.1001/jamaneurol.2018.1264

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

1132-1141

issue

9

eissn

2168-6149

issn

2168-6157

pii

2682656

journal_volume

75

pub_type

杂志文章,评审

相关文献

JAMA Neurology文献大全
  • Association of CAG Repeats With Long-term Progression in Huntington Disease.

    abstract：Importance:In Huntington disease (HD), mutation severity is defined by the length of the CAG trinucleotide sequence, a well-known predictor of clinical onset age. The association with disease trajectory is less well characterized. Quantifiable summary measures of trajectory applicable over decades of early disease prog...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2019.2368

    authors： Langbehn DR,Stout JC,Gregory S,Mills JA,Durr A,Leavitt BR,Roos RAC,Long JD,Owen G,Johnson HJ,Borowsky B,Craufurd D,Reilmann R,Landwehrmeyer GB,Scahill RI,Tabrizi SJ,TRACK-HD and Track-On HD Groups.

    更新日期：2019-08-12 00:00:00

  • Molecular Pathogenic Basis for GABRG2 Mutations Associated With a Spectrum of Epilepsy Syndromes, From Generalized Absence Epilepsy to Dravet Syndrome.

    abstract：OBJECTIVE:In this review article, we focus on the molecular pathogenic basis for genetic generalized epilepsies associated with mutations in the inhibitory γ-aminobutyric acid (GABAA) receptor γ2 subunit gene, GABRG2 (OMIM 137164), an established epilepsy gene. OBSERVATIONS:The γ-aminobutyric acid (GABAA) receptor γ2 ...

    journal_title：JAMA neurology

    pub_type： 杂志文章,评审

    doi：10.1001/jamaneurol.2016.0449

    authors： Kang JQ,Macdonald RL

    更新日期：2016-08-01 00:00:00

  • Endovascular Thrombectomy as a Means to Improve Survival in Acute Ischemic Stroke: A Meta-analysis.

    abstract：Importance:Although endovascular thrombectomy (EVT) in acute ischemic stroke is recommended by guidelines to improve functional recovery, thus far there are insufficient data on its association with mortality. Objective:To identify guideline-relevant trials of EVT vs medical therapy reporting 90-day mortality and perf...

    journal_title：JAMA neurology

    pub_type： 杂志文章,meta分析

    doi：10.1001/jamaneurol.2019.0525

    authors： Lin Y,Schulze V,Brockmeyer M,Parco C,Karathanos A,Heinen Y,Gliem M,Hartung HP,Antoch G,Jander S,Turowski B,Perings S,Kelm M,Wolff G

    更新日期：2019-07-01 00:00:00

  • Hereditary ataxia and spastic paraplegia in Portugal: a population-based prevalence study.

    abstract：IMPORTANCE:Epidemiological data on hereditary cerebellar ataxia (HCA) and hereditary spastic paraplegia (HSP) are scarce. OBJECTIVE:To present the prevalence and distribution of HCA and HSP in Portugal. DESIGN AND SETTING:Population-based, nationwide, systematic survey, from January 1, 1994, through April 15, 2004, i...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.1707

    authors： Coutinho P,Ruano L,Loureiro JL,Cruz VT,Barros J,Tuna A,Barbot C,Guimarães J,Alonso I,Silveira I,Sequeiros J,Marques Neves J,Serrano P,Silva MC

    更新日期：2013-06-01 00:00:00

  • Endovascular Treatment for Patients With Acute Stroke Who Have a Large Ischemic Core and Large Mismatch Imaging Profile.

    abstract：Importance:Endovascular therapy (ET) is typically not considered for patients with large baseline ischemic cores (irreversibly injured tissue). Computed tomographic perfusion (CTP) imaging may identify a subset of patients with large ischemic cores who remain at risk for significant infarct expansion and thus could sti...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2016.3954

    authors： Rebello LC,Bouslama M,Haussen DC,Dehkharghani S,Grossberg JA,Belagaje S,Frankel MR,Nogueira RG

    更新日期：2017-01-01 00:00:00

  • Blood pressure and progression of brain atrophy: the SMART-MR Study.

    abstract：IMPORTANCE:Studies have shown that both high and low blood pressure (BP) may play a role in the etiology of brain atrophy. High BP in midlife has been associated with more brain atrophy later in life, whereas studies in older populations have shown a relation between low BP and more brain atrophy. Yet, prospective evid...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.217

    authors： Jochemsen HM,Muller M,Visseren FL,Scheltens P,Vincken KL,Mali WP,van der Graaf Y,Geerlings MI,SMART Study Group.

    更新日期：2013-08-01 00:00:00

  • Outcomes of Intensive Systolic Blood Pressure Reduction in Patients With Intracerebral Hemorrhage and Excessively High Initial Systolic Blood Pressure: Post Hoc Analysis of a Randomized Clinical Trial.

    abstract：Importance:The safety and efficacy of intensive systolic blood pressure reduction in patients with intracerebral hemorrhage who present with systolic blood pressure greater than 220 mm Hg appears to be unknown. Objective:To evaluate the differential outcomes of intensive (goal, 110-139 mm Hg) vs standard (goal, 140-17...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2020.3075

    authors： Qureshi AI,Huang W,Lobanova I,Barsan WG,Hanley DF,Hsu CY,Lin CL,Silbergleit R,Steiner T,Suarez JI,Toyoda K,Yamamoto H,for ATACH-II trial investigators.

    更新日期：2020-09-08 00:00:00

  • Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review.

    abstract：Importance:Scientific and lay interest in negative outcomes associated with exposure to repetitive brain trauma (RBT) continues to strengthen. Concerns about the association between RBT and dementia began more than a century ago, but have resurfaced in the last decade with the more recently described chronic traumatic ...

    journal_title：JAMA neurology

    pub_type： 杂志文章,评审

    doi：10.1001/jamaneurol.2017.2396

    authors： Asken BM,Sullan MJ,DeKosky ST,Jaffee MS,Bauer RM

    更新日期：2017-10-01 00:00:00

  • Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals.

    abstract：IMPORTANCE:Magnetic resonance imaging markers of incipient cognitive decline among healthy elderly individuals have become important for both clarifying the biological underpinnings of dementia and clinically identifying healthy individuals at high risk of cognitive decline. Even though the role of hippocampal atrophy ...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.3263

    authors： Fletcher E,Raman M,Huebner P,Liu A,Mungas D,Carmichael O,DeCarli C

    更新日期：2013-11-01 00:00:00

  • Assessment of Safety and Efficacy of Safinamide as a Levodopa Adjunct in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial.

    abstract：Importance:Although levodopa remains the most effective oral pharmacotherapy for Parkinson disease (PD), its use is often limited by wearing off effect and dyskinesias. Management of such complications continues to be a significant challenge. Objective:To investigate the efficacy and safety of safinamide (an oral amin...

    journal_title：JAMA neurology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1001/jamaneurol.2016.4467

    authors： Schapira AH,Fox SH,Hauser RA,Jankovic J,Jost WH,Kenney C,Kulisevsky J,Pahwa R,Poewe W,Anand R

    更新日期：2017-02-01 00:00:00

  • Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB.

    abstract：Importance:Early-onset Alzheimer disease (EOAD) is a rare form of Alzheimer disease (AD) with a large genetic basis that is only partially understood. In late-onset AD, elevated circulating cholesterol levels increase AD risk even after adjusting for the apolipoprotein E ε4 (APOE E4) allele, a major genetic factor for ...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2019.0648

    authors： Wingo TS,Cutler DJ,Wingo AP,Le NA,Rabinovici GD,Miller BL,Lah JJ,Levey AI

    更新日期：2019-07-01 00:00:00

  • A Histologic Study of the Circadian System in Parkinson Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy.

    abstract：Importance:Circadian dysfunction may be associated with the symptoms and neurodegeneration in Parkinson disease (PD), multiple system atrophy (MSA), and progressive supranuclear palsy (PSP), although the underlying neuroanatomical site of disruption and pathophysiological mechanisms are not fully understood. Objective...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2018.0640

    authors： De Pablo-Fernández E,Courtney R,Warner TT,Holton JL

    更新日期：2018-08-01 00:00:00

  • Intractable Epilepsy and Progressive Cognitive Decline in a Young Man.

    abstract：:A young man with normal neurodevelopment presented with 3 years of medically refractory, progressive epilepsy and myoclonus. Initial examination included neuroimaging, electroencephalography, and biochemical analyses, all of which were unremarkable except for mildly enlarged ventricles. Over the following year, the pa...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2016.3195

    authors： Cohen AL,Jones LK,Parisi JE,Klaas JP

    更新日期：2017-06-01 00:00:00

  • Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease.

    abstract：IMPORTANCE:Neurogranin (NGRN) seems to be a promising novel cerebrospinal fluid (CSF) biomarker for synaptic loss; however, clinical, and especially longitudinal, data are sparse. OBJECTIVE:To examine the utility of NGRN, with repeated CSF sampling, for diagnosis, prognosis, and monitoring of Alzheimer disease (AD). ...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2015.1867

    authors： Kester MI,Teunissen CE,Crimmins DL,Herries EM,Ladenson JH,Scheltens P,van der Flier WM,Morris JC,Holtzman DM,Fagan AM

    更新日期：2015-11-01 00:00:00

  • Ischemic stroke and transient ischemic attack in young adults: risk factors, diagnostic yield, neuroimaging, and thrombolysis.

    abstract：BACKGROUND:Approximately 10% to 14% of ischemic strokes occur in young adults. OBJECTIVE:To investigate the yield of diagnostic tests, neuroimaging findings, and treatment of ischemic strokes in young adults. DESIGN:We retrospectively reviewed data from our Get with the Guidelines-Stroke database from 2005 through 20...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.575

    authors： Ji R,Schwamm LH,Pervez MA,Singhal AB

    更新日期：2013-01-01 00:00:00

  • Autoimmune aquaporin-4 myopathy in neuromyelitis optica spectrum.

    abstract：IMPORTANCE:Documentation of muscle pathology compatible with targeting of sarcolemmal aquaporin-4 (AQP4) by complement-activating IgG implies involvement of organs beyond the central nervous system in neuromyelitis optica spectrum disorders. OBSERVATIONS:We report on a 51-year-old woman who had relapsing optic neuriti...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2014.775

    authors： Guo Y,Lennon VA,Popescu BF,Grouse CK,Topel J,Milone M,Lassmann H,Parisi JE,Pittock SJ,Stefoski D,Balabanov R,Lucchinetti CF

    更新日期：2014-08-01 00:00:00

  • Longitudinally extensive transverse myelitis with and without aquaporin 4 antibodies.

    abstract：IMPORTANCE:Aquaporin 4 antibody (AQP4-Ab)-negative patients with longitudinally extensive transverse myelitis (LETM) behave differently from those with AQP4-Ab. Aquaporin 4 antibody-negative neuromyelitis optica (NMO) is rare when good assays are used. OBJECTIVE:To assess if AQP4-Ab-negative patients with LETM share s...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.3890

    authors： Kitley J,Leite MI,Küker W,Quaghebeur G,George J,Waters P,Woodhall M,Vincent A,Palace J

    更新日期：2013-11-01 00:00:00

  • Safety and Efficacy of Atorvastatin for Chronic Subdural Hematoma in Chinese Patients: A Randomized ClinicalTrial.

    abstract：Importance:Chronic subdural hematoma (CSDH) is a trauma-associated condition commonly found in elderly patients. Surgery is currently the treatment of choice, but it carries a significant risk of recurrence and death. Nonsurgical treatments remain limited and ineffective. Our recent studies suggest that atorvastatin re...

    journal_title：JAMA neurology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1001/jamaneurol.2018.2030

    authors： Jiang R,Zhao S,Wang R,Feng H,Zhang J,Li X,Mao Y,Yuan X,Fei Z,Zhao Y,Yu X,Poon WS,Zhu X,Liu N,Kang D,Sun T,Jiao B,Liu X,Yu R,Zhang J,Gao G,Hao J,Su N,Yin G,Zhu X,Lu Y,Wei J,Hu J,Hu R,Li J,Wang D

    更新日期：2018-11-01 00:00:00

  • Prevalence of Aging, Dementia, and Multimorbidity in Older Adults With Down Syndrome.

    abstract：Importance:As the life expectancy of people with Down syndrome (DS) has markedly increased over the past decades, older adults with DS may be experiencing a higher incidence of aging conditions. In addition to longevity, the amyloid precursor protein gene located on chromosome 21 places individuals with DS at a high ri...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2018.2210

    authors： Bayen E,Possin KL,Chen Y,Cleret de Langavant L,Yaffe K

    更新日期：2018-11-01 00:00:00

  • Secular Trends of Amyotrophic Lateral Sclerosis: The Piemonte and Valle d'Aosta Register.

    abstract：Importance:This study reports the long-term epidemiologic trends of amyotrophic lateral sclerosis (ALS) based on a prospective register. Objective:To examine the 20-year epidemiologic trends of ALS in the Piemonte and Valle d'Aosta regions of Italy. Design, Setting, and Participants:The Piemonte and Valle d'Aosta Reg...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2017.1387

    authors： Chiò A,Mora G,Moglia C,Manera U,Canosa A,Cammarosano S,Ilardi A,Bertuzzo D,Bersano E,Cugnasco P,Grassano M,Pisano F,Mazzini L,Calvo A,Piemonte and Valle d’Aosta Register for ALS (PARALS).

    更新日期：2017-09-01 00:00:00

  • JC polyomavirus granule cell neuronopathy in a patient treated with rituximab.

    abstract：IMPORTANCE:Progressive multifocal leukoencephalopathy results from lytic infection of the glia by the JC polyomavirus (JCV); JCV granule cell neuronopathy is caused by infection with a mutated form of JCV, leading to a shift in viral tropism from the glia to cerebellar granule cells. This shift results in a clinical sy...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.4668

    authors： Dang L,Dang X,Koralnik IJ,Todd PK

    更新日期：2014-04-01 00:00:00

  • The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction.

    abstract：IMPORTANCE:β-Amyloid (Aβ) deposition and vascular brain injury (VBI) frequently co-occur and are both associated with cognitive decline in aging. Determining whether a direct relationship exists between them has been challenging. We sought to understand VBI's influence on cognition and clinical impairment, separate fro...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/2013.jamaneurol.405

    authors： Marchant NL,Reed BR,Sanossian N,Madison CM,Kriger S,Dhada R,Mack WJ,DeCarli C,Weiner MW,Mungas DM,Chui HC,Jagust WJ

    更新日期：2013-04-01 00:00:00

  • Emerging therapies for glioblastoma.

    abstract：IMPORTANCE:Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the prognosis is poor, with a median survival of 16 to 19 months and poor quality of life throughout the disease course. New treatments are needed. EVIDE...

    journal_title：JAMA neurology

    pub_type： 杂志文章,评审

    doi：10.1001/jamaneurol.2014.1701

    authors： Thomas AA,Brennan CW,DeAngelis LM,Omuro AM

    更新日期：2014-11-01 00:00:00

  • Identifying Non-Duchenne Muscular Dystrophy-Positive and False Negative Results in Prior Duchenne Muscular Dystrophy Newborn Screening Programs: A Review.

    abstract：IMPORTANCE:Duchenne muscular dystrophy (DMD) is a candidate for the recommended universal screening panel based on evidence that early corticosteroid treatment improves outcomes and on new genetic therapies that require early diagnosis for effectiveness. Elevated creatine kinase levels in the neonatal period are the in...

    journal_title：JAMA neurology

    pub_type： 杂志文章,评审

    doi：10.1001/jamaneurol.2015.3537

    authors： Gatheridge MA,Kwon JM,Mendell JM,Scheuerbrandt G,Moat SJ,Eyskens F,Rockman-Greenberg C,Drousiotou A,Griggs RC

    更新日期：2016-01-01 00:00:00

  • Safety and Efficacy of Siponimod (BAF312) in Patients With Relapsing-Remitting Multiple Sclerosis: Dose-Blinded, Randomized Extension of the Phase 2 BOLD Study.

    abstract：IMPORTANCE:This dose-blinded extension of the phase 2 BOLD (BAF312 on MRI Lesion Given Once Daily) Study in relapsing-remitting multiple sclerosis provides evidence on disease activity and safety of a range of siponimod doses for up to 24 months. OBJECTIVE:To assess the safety and efficacy of siponimod for up to 24 mo...

    journal_title：JAMA neurology

    pub_type： 杂志文章,随机对照试验

    doi：10.1001/jamaneurol.2016.1451

    authors： Kappos L,Li DK,Stüve O,Hartung HP,Freedman MS,Hemmer B,Rieckmann P,Montalban X,Ziemssen T,Hunter B,Arnould S,Wallström E,Selmaj K

    更新日期：2016-09-01 00:00:00

  • Long-term Cognitive Outcomes in Patients With Pediatric-Onset vs Adult-Onset Multiple Sclerosis.

    abstract：Importance:Cognitive impairment in multiple sclerosis (MS) can lead to reduced quality of life, social functioning, and employment. Few studies have investigated cognitive outcomes among patients with pediatric-onset MS (POMS) over the long term. Objective:To compare long-term information-processing efficiency between...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2019.1546

    authors： McKay KA,Manouchehrinia A,Berrigan L,Fisk JD,Olsson T,Hillert J

    更新日期：2019-06-17 00:00:00

  • Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.

    abstract：Importance:Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for Alzheimer disease. While APOEε4 is associated with increased amyloid-β burden, its association with cerebral tau pathology has been controversial. Objective:To determine whether APOEε4 is associated with medial temporal tau pa...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2019.4421

    authors： Therriault J,Benedet AL,Pascoal TA,Mathotaarachchi S,Chamoun M,Savard M,Thomas E,Kang MS,Lussier F,Tissot C,Parsons M,Qureshi MNI,Vitali P,Massarweh G,Soucy JP,Rej S,Saha-Chaudhuri P,Gauthier S,Rosa-Neto P

    更新日期：2020-04-01 00:00:00

  • Retinal Architecture and Melanopsin-Mediated Pupillary Response Characteristics: A Putative Pathophysiologic Signature for the Retino-Hypothalamic Tract in Multiple Sclerosis.

    abstract：Importance:A neurophysiologic signature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with potential utility for investigating alterations in homeostatic mechanisms associated with brain disor...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2016.5131

    authors： Meltzer E,Sguigna PV,Subei A,Beh S,Kildebeck E,Conger D,Conger A,Lucero M,Frohman BS,Frohman AN,Saidha S,Galetta S,Calabresi PA,Rennaker R,Frohman TC,Kardon RH,Balcer LJ,Frohman EM

    更新日期：2017-05-01 00:00:00

  • Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping.

    abstract：OBJECTIVE:To determine, in patients identified as seropositive for neuronal voltage-gated potassium channel (VGKC) complex autoantibodies, the spectrum of clinical presentations and frequency of leucine-rich glioma-inactivated protein 1 (LGI1) and contactin-associated protein-like 2 (CASPR2) as defined antigenic neuron...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2013.592

    authors： Klein CJ,Lennon VA,Aston PA,McKeon A,O'Toole O,Quek A,Pittock SJ

    更新日期：2013-02-01 00:00:00

  • Cognitive resilience to apolipoprotein E ε4: contributing factors in black and white older adults.

    abstract：IMPORTANCE:Apolipoprotein E (APOE) ε4 is an established risk factor for cognitive decline and the development of dementia, but other factors may help to minimize its effects. OBJECTIVE:Using APOE ε4 as an indicator of high risk, we investigated factors associated with cognitive resilience among black and white older a...

    journal_title：JAMA neurology

    pub_type： 杂志文章

    doi：10.1001/jamaneurol.2014.3978

    authors： Kaup AR,Nettiksimmons J,Harris TB,Sink KM,Satterfield S,Metti AL,Ayonayon HN,Yaffe K,Health, Aging, and Body Composition (Health ABC) Study.

    更新日期：2015-03-01 00:00:00