Live cyanobacteria produce photocurrent and hydrogen using both the respiratory and photosynthetic systems.

abstract：:Soil bacterial diversity varies across biomes with potential impacts on soil ecological functioning. Here, we incorporate key factors that affect soil bacterial abundance and diversity across spatial scales into a mechanistic modeling framework considering soil type, carbon inputs and climate towards predicting soil b...

journal_title：Nature communications

authors： Bickel S,Or D

更新日期：2020-01-08 00:00:00

abstract：:Electrospun nanofibres are promising in biomedical applications to replicate features of the natural extracellular matrix (ECM). However, nearly all electrospun scaffolds are either non-degradable or degrade hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases. Here we ...

journal_title：Nature communications

authors： Wade RJ,Bassin EJ,Rodell CB,Burdick JA

更新日期：2015-03-23 00:00:00

abstract：:Erythropoietin regulates erythropoiesis in a hypoxia-inducible manner. Here we generate inherited super-anaemic mice (ISAM) as a mouse model of adult-onset anaemia caused by erythropoietin deficiency. ISAM express erythropoietin in the liver but lack erythropoietin production in the kidney. Around weaning age, when th...

journal_title：Nature communications

authors： Yamazaki S,Souma T,Hirano I,Pan X,Minegishi N,Suzuki N,Yamamoto M

更新日期：2013-01-01 00:00:00

abstract：:The gyrotropic rotation around the equilibrium position constitutes the fundamental excitation of magnetic vortices in nanostructures. The frequency of this mode varies with material and sample geometry, but is independent of the vortex handedness and its core direction. Here, we demonstrate that this degeneracy is li...

journal_title：Nature communications

authors： Sluka V,Kákay A,Deac AM,Bürgler DE,Schneider CM,Hertel R

更新日期：2015-03-03 00:00:00

abstract：:When two periodic potentials compete in materials, one may adopt the other, which straightforwardly generates topological defects. Of particular interest are domain walls in charge-, dipole-, and spin-ordered systems, which govern macroscopic properties and important functionality. However, detailed atomic and electro...

journal_title：Nature communications

authors： Park JW,Cho GY,Lee J,Yeom HW

更新日期：2019-09-06 00:00:00

abstract：:The endoplasmic reticulum-mitochondria encounter structure (ERMES) connects the mitochondrial outer membrane with the ER. Multiple functions have been linked to ERMES, including maintenance of mitochondrial morphology, protein assembly and phospholipid homeostasis. Since the mitochondrial distribution and morphology p...

journal_title：Nature communications

authors： Ellenrieder L,Opaliński Ł,Becker L,Krüger V,Mirus O,Straub SP,Ebell K,Flinner N,Stiller SB,Guiard B,Meisinger C,Wiedemann N,Schleiff E,Wagner R,Pfanner N,Becker T

更新日期：2016-10-10 00:00:00

abstract：:Zoonotic transmission of lethal henipaviruses (HNVs) from their natural fruit bat reservoirs to humans has only been reported in Australia and South/Southeast Asia. However, a recent study discovered numerous HNV clades in African bat samples. To determine the potential for HNV spillover events among humans in Africa,...

journal_title：Nature communications

authors： Pernet O,Schneider BS,Beaty SM,LeBreton M,Yun TE,Park A,Zachariah TT,Bowden TA,Hitchens P,Ramirez CM,Daszak P,Mazet J,Freiberg AN,Wolfe ND,Lee B

更新日期：2014-11-18 00:00:00

abstract：:Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectric...

journal_title：Nature communications

authors： Zillikens MC,Demissie S,Hsu YH,Yerges-Armstrong LM,Chou WC,Stolk L,Livshits G,Broer L,Johnson T,Koller DL,Kutalik Z,Luan J,Malkin I,Ried JS,Smith AV,Thorleifsson G,Vandenput L,Hua Zhao J,Zhang W,Aghdassi A,Åkesson

更新日期：2017-07-19 00:00:00

abstract：:Cell biologists generally consider that microtubules and actin play complementary roles in long- and short-distance transport in animal cells. On the contrary, using melanosomes of melanocytes as a model, we recently discovered that the motor protein myosin-Va works with dynamic actin tracks to drive long-range organe...

journal_title：Nature communications

authors： Alzahofi N,Welz T,Robinson CL,Page EL,Briggs DA,Stainthorp AK,Reekes J,Elbe DA,Straub F,Kallemeijn WW,Tate EW,Goff PS,Sviderskaya EV,Cantero M,Montoliu L,Nedelec F,Miles AK,Bailly M,Kerkhoff E,Hume AN

更新日期：2020-07-13 00:00:00

abstract：:Voltage-gated sodium channels (Na(v)) underlie the rapid upstroke of action potentials in excitable tissues. Binding of channel-interactive proteins is essential for controlling fast and long-term inactivation. In the structure of the complex of the carboxy-terminal portion of Na(v)1.5 (CTNa(v)1.5) with calmodulin (Ca...

journal_title：Nature communications

authors： Gabelli SB,Boto A,Kuhns VH,Bianchet MA,Farinelli F,Aripirala S,Yoder J,Jakoncic J,Tomaselli GF,Amzel LM

更新日期：2014-11-05 00:00:00

abstract：:The extraction and combustion of fossil natural gas, consisting primarily of methane, generates vast amounts of greenhouse gases that contribute to climate change. However, as a result of recent research efforts, "solar methane" can now be produced through the photocatalytic conversion of carbon dioxide and water to m...

journal_title：Nature communications

authors： Ulmer U,Dingle T,Duchesne PN,Morris RH,Tavasoli A,Wood T,Ozin GA

更新日期：2019-07-18 00:00:00

abstract：:Atropisomers are important organic frameworks in bioactive natural products, drugs as well as chiral catalysts. Meanwhile, silanols display unique properties compared to their alcohol analogs, however, the catalytic synthesis of atropisomers bearing silanol groups is challenging. Here, we show a rhodium-catalyzed tors...

journal_title：Nature communications

authors： Feng J,Bi X,Xue X,Li N,Shi L,Gu Z

更新日期：2020-09-07 00:00:00

abstract：:Detection of Identical-By-Descent (IBD) segments provides a fundamental measure of genetic relatedness and plays a key role in a wide range of analyses. We develop FastSMC, an IBD detection algorithm that combines a fast heuristic search with accurate coalescent-based likelihood calculations. FastSMC enables biobank-s...

journal_title：Nature communications

authors： Nait Saada J,Kalantzis G,Shyr D,Cooper F,Robinson M,Gusev A,Palamara PF

更新日期：2020-11-30 00:00:00

abstract：:Targeting the vasculature remains a promising approach for treating solid tumours; however, the mechanisms of tumour neovascularization are diverse and complex. Here we uncover a new subpopulation of melanoma cells that express the vascular cell adhesion molecule PECAM1, but not VEGFR-2, and participate in a PECAM1-de...

journal_title：Nature communications

authors： Dunleavey JM,Xiao L,Thompson J,Kim MM,Shields JM,Shelton SE,Irvin DM,Brings VE,Ollila DW,Brekken RA,Dayton PA,Melero-Martin JM,Dudley AC

更新日期：2014-10-22 00:00:00

abstract：:Graphite dual-ion batteries represent a potential battery concept for large-scale stationary storage of electricity, especially when constructed free of lithium and other chemical elements with limited natural reserves. Owing to their non-rocking-chair operation mechanism, however, the practical deployment of graphite...

journal_title：Nature communications

authors： Kravchyk KV,Bhauriyal P,Piveteau L,Guntlin CP,Pathak B,Kovalenko MV

更新日期：2018-10-26 00:00:00

abstract：:The competition between bimolecular nucleophilic substitution and base-induced elimination is of fundamental importance for the synthesis of pure samples in organic chemistry. Many factors that influence this competition have been identified over the years, but the underlying atomistic dynamics have remained difficult...

journal_title：Nature communications

authors： Carrascosa E,Meyer J,Zhang J,Stei M,Michaelsen T,Hase WL,Yang L,Wester R

更新日期：2017-06-21 00:00:00

abstract：:HER2-targeted therapy has yielded a significant clinical benefit in patients with HER2+ breast cancer, yet disease relapse due to intrinsic or acquired resistance remains a significant challenge in the clinic. Here, we show that the protein phosphatase 2A (PP2A) regulatory subunit PPP2R2B is a crucial determinant of a...

journal_title：Nature communications

authors： Bao Y,Oguz G,Lee WC,Lee PL,Ghosh K,Li J,Wang P,Lobie PE,Ehmsen S,Ditzel HJ,Wong A,Tan EY,Lee SC,Yu Q

更新日期：2020-11-18 00:00:00

abstract：:This corrects the article DOI: 10.1038/ncomms15317. ...

journal_title：Nature communications

authors： Lovrak M,Hendriksen WEJ,Maity C,Mytnyk S,van Steijn V,Eelkema R,van Esch JH

更新日期：2017-06-30 00:00:00

abstract：:Control over interactions with biomolecules holds the key to applications of graphene in biotechnology. One such application is nanopore sequencing, where a DNA molecule is electrophoretically driven through a graphene nanopore. Here we investigate how interactions of single-stranded DNA and a graphene membrane can be...

journal_title：Nature communications

authors： Shankla M,Aksimentiev A

更新日期：2014-10-09 00:00:00

abstract：:DNA is a promising molecule for applications in molecular electronics because of its unique electronic and self-assembly properties. Here we report that the conductance of DNA duplexes increases by approximately one order of magnitude when its conformation is changed from the B-form to the A-form. This large conductan...

journal_title：Nature communications

authors： Artés JM,Li Y,Qi J,Anantram MP,Hihath J

更新日期：2015-12-09 00:00:00

abstract：:The HIV Tat protein competes with the 7SK:HEXIM interaction to hijack pTEFb from 7SK snRNP and recruit it to the TAR motif on stalled viral transcripts. Here we solve structures of 7SK stemloop-1 and TAR in complex with Tat's RNA binding domain (RBD) to gain insights into this process. We find that 7SK is peppered wit...

journal_title：Nature communications

authors： Pham VV,Salguero C,Khan SN,Meagher JL,Brown WC,Humbert N,de Rocquigny H,Smith JL,D'Souza VM

更新日期：2018-10-15 00:00:00

abstract：:Clonal proliferation in myeloproliferative neoplasms (MPN) is driven by somatic mutations in JAK2, CALR or MPL, but the contribution of inherited factors is poorly characterized. Using a three-stage genome-wide association study of 3,437 MPN cases and 10,083 controls, we identify two SNPs with genome-wide significance...

journal_title：Nature communications

authors： Tapper W,Jones AV,Kralovics R,Harutyunyan AS,Zoi K,Leung W,Godfrey AL,Guglielmelli P,Callaway A,Ward D,Aranaz P,White HE,Waghorn K,Lin F,Chase A,Baxter EJ,Maclean C,Nangalia J,Chen E,Evans P,Short M,Jack A,Wal

更新日期：2015-04-07 00:00:00

abstract：:Calcium ions (Ca(2+)) function as universal second messengers in eukaryotic cells, including immune cells. Ca(2+) is crucial for peripheral T-lymphocyte activation and effector functions, and influences thymocyte selection and motility in the developing thymus. However, the role of Ca(2+) signalling in early T-lymphoc...

journal_title：Nature communications

authors： Ouyang K,Leandro Gomez-Amaro R,Stachura DL,Tang H,Peng X,Fang X,Traver D,Evans SM,Chen J

更新日期：2014-09-12 00:00:00

abstract：:Cell-to-cell variability (noise) is an important feature of gene expression that impacts cell fitness and development. The regulatory mechanism of this variability is not fully understood. Here we investigate the effect on gene expression noise in divergent gene pairs (DGPs). We generated reporters driven by divergent...

journal_title：Nature communications

authors： Yan C,Wu S,Pocetti C,Bai L

更新日期：2016-03-24 00:00:00

abstract：:The decoy effect is a cognitive bias documented in behavioural economics by which the presence of a third, (partly) inferior choice causes a significant shift in people's preference for other items. Here, we performed an experiment with human volunteers who played a variant of the repeated prisoner's dilemma game in w...

journal_title：Nature communications

authors： Wang Z,Jusup M,Shi L,Lee JH,Iwasa Y,Boccaletti S

更新日期：2018-07-27 00:00:00

abstract：:1T-MoS2 and single-atom modified analogues represent a highly promising class of low-cost catalysts for hydrogen evolution reaction (HER). However, the role of single atoms, either as active species or promoters, remains vague despite its essentiality toward more efficient HER. In this work, we report the unambiguous ...

journal_title：Nature communications

authors： Pattengale B,Huang Y,Yan X,Yang S,Younan S,Hu W,Li Z,Lee S,Pan X,Gu J,Huang J

更新日期：2020-08-17 00:00:00

abstract：:Biocatalytic cyclization is highly desirable for efficient synthesis of biologically derived chemical substances, such as the commodity chemicals ε-caprolactam and δ-valerolactam. To identify biocatalysts in lactam biosynthesis, we develop a caprolactam-detecting genetic enzyme screening system (CL-GESS). The Alcalige...

journal_title：Nature communications

authors： Yeom SJ,Kim M,Kwon KK,Fu Y,Rha E,Park SH,Lee H,Kim H,Lee DH,Kim DM,Lee SG

更新日期：2018-11-29 00:00:00

abstract：:Deep understanding of the genomic and immunological differences between Chinese and Western lung cancer patients is of great importance for target therapy selection and development for Chinese patients. Here we report an extensive molecular and immune profiling study of 245 Chinese patients with non-small cell lung ca...

journal_title：Nature communications

authors： Zhang XC,Wang J,Shao GG,Wang Q,Qu X,Wang B,Moy C,Fan Y,Albertyn Z,Huang X,Zhang J,Qiu Y,Platero S,Lorenzi MV,Zudaire E,Yang J,Cheng Y,Xu L,Wu YL

更新日期：2019-04-16 00:00:00

abstract：:FBXW2 inhibits proliferation of lung cancer cells by targeting SKP2 for degradation. Whether and how FBXW2 regulates tumor invasion and metastasis is previously unknown. Here, we report that FBXW2 is an E3 ligase for β-catenin. FBXW2 binds to β-catenin upon EGF-AKT1-mediated phosphorylation on Ser552, and promotes its...

journal_title：Nature communications

authors： Yang F,Xu J,Li H,Tan M,Xiong X,Sun Y

更新日期：2019-03-27 00:00:00

abstract：:The precise measurement of forces is one way to obtain deep insight into the fundamental interactions present in nature. In the context of neutral antimatter, the gravitational interaction is of high interest, potentially revealing new forces that violate the weak equivalence principle. Here we report on a successful ...

journal_title：Nature communications

authors： Aghion S,Ahlén O,Amsler C,Ariga A,Ariga T,Belov AS,Berggren K,Bonomi G,Bräunig P,Bremer J,Brusa RS,Cabaret L,Canali C,Caravita R,Castelli F,Cerchiari G,Cialdi S,Comparat D,Consolati G,Derking H,Di Domizio S,Di N

更新日期：2014-07-28 00:00:00