A comparison of various MRI feature types for characterizing whole brain anatomical differences using linear pattern recognition methods.

Abstract:

:There is a widespread interest in applying pattern recognition methods to anatomical neuroimaging data, but so far, there has been relatively little investigation into how best to derive image features in order to make the most accurate predictions. In this work, a Gaussian Process machine learning approach was used for predicting age, gender and body mass index (BMI) of subjects in the IXI dataset, as well as age, gender and diagnostic status using the ABIDE and COBRE datasets. MRI data were segmented and aligned using SPM12, and a variety of feature representations were derived from this preprocessing. We compared classification and regression accuracy using the different sorts of features, and with various degrees of spatial smoothing. Results suggested that feature sets that did not ignore the implicit background tissue class, tended to result in better overall performance, whereas some of the most commonly used feature sets performed relatively poorly.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Monté-Rubio GC,Falcón C,Pomarol-Clotet E,Ashburner J

doi

10.1016/j.neuroimage.2018.05.065

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

753-768

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(18)30491-9

journal_volume

178

pub_type

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