Abstract:
RATIONALE:Despite the approval of antiangiogenic therapy for high grade glioma (HGG) patients, survival benefits are still limited. New treatment plans have always been developed to improve the survival. PATIENT CONCERNS:A 26-year-old woman was admitted to our hospital for distending pain of head and eye. DIAGNOSES:Resonance imaging (MRI) revealed a large spherical heterogeneously enhancing, mixed cystic and solid mass in the right frontal region, and the midline shifted. INTERVENTION:The patient received apatinib therapy for positive vascular endothelial growth factor. OUTCOMES:A partial response was observed after 4 weeks and remains sustained until now. LESSONS:It suggests that apatinib might be a feasible option for the treatment in advanced HGG patients or patients with poor physical condition.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Ding X,Sun J,Fan T,Li Bdoi
10.1097/MD.0000000000010859subject
Has Abstractpub_date
2018-06-01 00:00:00pages
e10859issue
22eissn
0025-7974issn
1536-5964pii
00005792-201806010-00028journal_volume
97pub_type
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