Abstract:
:Meige Syndrome (MS) is a disabling movement disorder which impairs daily routines such as eating and speaking and, when not responsive to best medical treatment, deep brain stimulation (DBS) of the globus pallidus interna (GPi) has been considered. Previous evidence has shown a significant improvement in motor dysfunction with DBS, however its benefit on disease-specific disability and quality of life has not been thoroughly studied. We describe two patients with severe MS submitted to GPi-DBS. Patient improvement was assessed preoperatively and 24 months after the surgery by applying the movement subscore of the Burke-Fahn-Marsden Dystonia Rating Scale (BFMRS) and Jankovic Rating Scale (JRS) for motor function and the BFMRS disability subscore and Blepharospasm Disability Scale (BDS) for disability. At 24-month follow-up, dystonia improved 68% in Patient 1 and 96% in Patient 2, while disability improved 77%-92% respectively. No major adverse effects were observed. Improvement in motor function is in agreement with previous findings, but we emphasise the important improvement in disability and consequently in quality of life. Therefore, we suggest that DBS should be a therapeutic tool in refractory cases of MS.
journal_name
Clin Neurol Neurosurgjournal_title
Clinical neurology and neurosurgeryauthors
Aires A,Gomes T,Linhares P,Cunha F,Rosas MJ,Vaz Rdoi
10.1016/j.clineuro.2018.05.012subject
Has Abstractpub_date
2018-08-01 00:00:00pages
53-57eissn
0303-8467issn
1872-6968pii
S0303-8467(18)30194-Xjournal_volume
171pub_type
杂志文章,评审abstract:PURPOSE:To develop and validate a model for identifying the risk factors of poor recovery in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS:A prediction model was developed using training data obtained from 1577 aSAH patients from multiple centers. The patients were followed for 6 months on average a...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:The National Institute for Health and Clinical Excellence (NICE) guidelines for multiple sclerosis (MS) recommend the time from initial presentation to first neurological evaluation to be no longer than 6 weeks, and a further 6 weeks until any necessary investigations are completed. The aim of this study was...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2013.09.025
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journal_title:Clinical neurology and neurosurgery
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doi:10.1016/j.clineuro.2009.12.002
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.clineuro.2014.06.011
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.clineuro.2004.05.003
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2010.11.001
更新日期:2011-04-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2008.04.001
更新日期:2008-07-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.clineuro.2019.105529
更新日期:2019-11-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2020.105719
更新日期:2020-05-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2017.03.011
更新日期:2017-06-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.clineuro.2008.01.014
更新日期:2008-11-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2014.12.013
更新日期:2015-03-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2018.01.027
更新日期:2018-03-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2020.106219
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2017.09.004
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2004.11.020
更新日期:2005-10-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2014.04.011
更新日期:2014-07-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2004.02.011
更新日期:2004-06-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.clineuro.2005.05.006
更新日期:2006-06-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
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pub_type: 杂志文章
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