Abstract:
:Biomedical device-associated infection (BAI) and lack of osseointegration are the main causes of implant failure. Therefore, it is imperative for implants not only to depress microbial activity and biofilm colonization but also to prompt osteoblast functions and osseointegration. As part of the coating development for implants, the interest of in vitro studies on the interaction between implant substrate morphology and the coating's biological performances is growing. In this study, by harnessing the adhesion and reactivity of bioinspired polydopamine, nano-silver was successfully anchored onto micro/nanoporous as well as smooth titanium surfaces to analyse the effect of substrate morphology on biological performances of the coatings. Compared with the smooth surface, a small size of nano-silver and high silver content was found on the micro/nanoporous surface. More mineralization happened on the coating on the micro/nanoporous structure than on the smooth surface, which led to a more rapid decrease of silver release from the micro/nanoporous surface. Antimicrobial tests indicated that both surfaces with resulting coating inhibit microbial colonization on them and growth around them, indicating that the coating eliminates the shortcoming of the porous structure which render the implant extremely susceptible to BAI. Besides, the multiple osteoblast responses of nano-silver-loaded dopamine coatings on both surfaces, i.e. attachment, proliferation and differentiation, have deteriorated, however the mineralized surfaces of these coatings stimulated osteoblast proliferation and differentiation, especially for the micro/nanoporous surface. Therefore, nano-silver-loaded dopamine coatings on micro/nanoporous substratum may not only reduce the risk of infection but also facilitate mineralization during the early post-operative period and then promote osseointegration owing to the good osteoblast-biocompatibility of the mineralized surface. These results clearly highlight the influence of the substrate morphology on the biological performances of implant coating.
journal_name
R Soc Open Scijournal_title
Royal Society open scienceauthors
Zhang W,Wang S,Ge S,Chen J,Ji Pdoi
10.1098/rsos.172310subject
Has Abstractpub_date
2018-04-11 00:00:00pages
172310issue
4issn
2054-5703pii
rsos172310journal_volume
5pub_type
杂志文章abstract::In this study, salting-out assisted liquid-liquid extraction (SALLE) as a simple and efficient extraction technique followed by high-performance liquid chromatography (HPLC) was employed for the determination of vitamin D3 in milk samples. The sample treatment is based on the use of water-miscible acetonitrile as the ...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.190952
更新日期:2019-08-21 00:00:00
abstract::Avoiding biological contaminants is a well-known manifestation of the adaptive system of disgust. In theory, animals evolved with such a system to prevent pathogen and parasite infection. Bodily products are human-universal disgust elicitors, but whether they also elicit avoidance behaviour in non-human primates has y...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.170968
更新日期:2017-11-08 00:00:00
abstract::[This corrects the article DOI: 10.1098/rsos.181295.]. ...
journal_title:Royal Society open science
pub_type: 已发布勘误
doi:10.1098/rsos.201358
更新日期:2020-09-16 00:00:00
abstract::In this work, we perform a comprehensive theoretical study on adsorption of representative 10-electron molecules H2O, CH4 and NH3 onto defective single-walled carbon nanotubes. Results of adsorption energy and charge transfer reveal the existence of both chemical adsorption (CA) and physical adsorption (PA). While PA ...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.190727
更新日期:2019-08-14 00:00:00
abstract::In this study, an environmentally friendly extraction method for flavonoid compound from Ixora javanica, as a new raw material candidate for herbal medicine and cosmetics, was developed. The objectives of the present work were to provide recommendations for the optimal extraction conditions and to investigate the effe...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.201116
更新日期:2020-10-07 00:00:00
abstract::A new Triassic neopterygian is described on the basis of a large three-dimensional neurocranium from the Rhaetian (Late Triassic) of the Kössen Formation (Schesaplana, Grisons, Switzerland). CT scanning reveals neurocranial features similar to Dapedium, suggesting that this new genus, Scopulipiscis saxciput gen. et sp...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.180497
更新日期:2018-08-15 00:00:00
abstract::By the slight adjustment of oxides constituting thin film transistor-liquid crystal display (TFT-LCD) substrate glass, including equal mole fraction substitution of Al2O3, GeO2, B2O3, P2O5 and ZrO2 for SiO2, as well as the substitution of CaO for SrO with the total contents unchanged, the structural and physico-chemic...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.191425
更新日期:2020-01-15 00:00:00
abstract::When mothers continue to support their offspring beyond infancy, they can influence the fitness of those offspring, the strength of social relationships within their groups, and the life-history traits of their species. Using up to 30 years of demographic data from 58 groups of gorillas in two study sites, this study ...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.160533
更新日期:2016-10-19 00:00:00
abstract::The electrochemical performance of an energy conversion and storage device like the supercapacitor mainly depends on the microstructure and morphology of the electrodes. In this paper, to improve the capacitance performance of the supercapacitor, the all-pseudocapacitive electrodes of lamella-like Bi18SeO29/BiSe as th...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.171186
更新日期:2018-01-10 00:00:00
abstract::Humans commonly engage in a variety of search behaviours, for example when looking for an object, a partner, information or a solution to a complex problem. The success or failure of a search strategy crucially depends on the structure of the environment and the constraints it imposes on the individuals. Here, we focu...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.190529
更新日期:2019-10-30 00:00:00
abstract::Metabolism is the only biological system that can be fully modelled at genome scale. As a result, metabolic models have been increasingly used to study the molecular mechanisms of various diseases. Hypoxia, a low-oxygen tension, is a well-known characteristic of many cancer cells. Pyruvate dehydrogenase (PDH) controls...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.170360
更新日期:2017-10-25 00:00:00
abstract::Facial attractiveness is often studied on the basis of the internal facial features alone. This study investigated how this exclusion of the external features affects the perception of attractiveness. We studied the effects of two most commonly used methods of exclusion, where the shape of an occluding mask was define...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.171616
更新日期:2018-06-20 00:00:00
abstract::[This corrects the article DOI: 10.1098/rsos.181113.]. ...
journal_title:Royal Society open science
pub_type: 杂志文章,已发布勘误
doi:10.1098/rsos.190045
更新日期:2019-01-30 00:00:00
abstract::Here we examined the kinematic function of the morpho- logically unique first thoracic vertebra in giraffes. The first thoracic vertebra of the giraffe displayed similar shape to the seventh cervical vertebra in general ruminants. The flexion experiment using giraffe carcasses demonstrated that the first thoracic vert...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.150604
更新日期:2016-02-03 00:00:00
abstract::Four model polyurethane (PU) hard segments were synthesized by reaction of butanol with four typical diisocyanates. The four diisocyanates were aromatic 4,4'-diphenylmethane diisocyanate (4,4'-MDI) and MDI-50 (50% mixture of 2,4'-MDI and 4,4'-MDI), cycloaliphatic 4,4'-dicyclohexylmethane diisocyanate (HMDI) and linear...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.180536
更新日期:2018-07-25 00:00:00
abstract::The persistence of homological features in simplicial complex representations of big datasets in R n resulting from Vietoris-Rips or Čech filtrations is commonly used to probe the topological structure of such datasets. In this paper, the notion of homological pers...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.160228
更新日期:2016-10-26 00:00:00
abstract::A global response function (GRF) of an elastic network is introduced as a generalization of the response function (RF) of a rigid network, relating the average flow along the network with the pressure difference at its extremes. The GRF can be used to explore the frequency behaviour of a fluid confined in a tree-like ...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.190661
更新日期:2019-09-25 00:00:00
abstract::We review the current state of knowledge of magnetic fields inside stars, concentrating on recent developments concerning magnetic fields in stably stratified (zones of) stars, leaving out convective dynamo theories and observations of convective envelopes. We include the observational properties of A, B and O-type ma...
journal_title:Royal Society open science
pub_type: 杂志文章,评审
doi:10.1098/rsos.160271
更新日期:2017-02-22 00:00:00
abstract::Adult body size in holometabolus insects is directly proportional to the time spent during the larval period. The larval duration can be divided into two parts: (i) pre-critical duration-time required to attain a critical size/critical weight that would result in successful completion of development and metamorphosis ...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.191910
更新日期:2020-06-10 00:00:00
abstract::[This corrects the article DOI: 10.1098/rsos.150635.]. ...
journal_title:Royal Society open science
pub_type: 已发布勘误
doi:10.1098/rsos.201430
更新日期:2020-11-11 00:00:00
abstract::In this contribution, olefin block copolymers were produced via chain shuttling polymerization (CSP), using a new combination of catalysts and a chain shuttling agent (CSA) diethylzinc (ZnEt2). The binary catalyst system included nonbridged half-titanocene catalyst, Cp*TiCl2(O-2,6-iPr2C6H3) (Cat A) and bis(phenoxy-imi...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.182007
更新日期:2019-04-10 00:00:00
abstract::Many species worldwide are impacted by habitat loss. This may result in increased competition both within species and between species. Many studies have demonstrated that when two previously non-overlapping species are forced to compete over a resource, one species is likely to become dominant over the other. This stu...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.160621
更新日期:2017-01-18 00:00:00
abstract::Miniaturized accelerometers are necessary for evaluating the performance of small devices, such as haptics, robotics and simulators. In this study, we fabricated miniaturized accelerometers using well-aligned ZnO nanowires. The layer of ZnO nanowires is used for active piezoelectric layer of the accelerometer, and cop...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.170557
更新日期:2017-09-13 00:00:00
abstract::Wildlife researchers often rely on demographic data collected from harvested animals to estimate population dynamics. But demographic data from harvested animals may be non-representative if hunters/trappers have the ability and motivation to preferentially select for certain physical traits. Hunter preference is well...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.180668
更新日期:2018-10-10 00:00:00
abstract::Natural selection favours a restricted host breadth in disease vector mosquitoes, indicating that there is an adaptive value associated with maintaining plasticity in host preference. One mechanism to maintain such plasticity is via the detection of generic cues by conserved peripheral olfactory pathways, which when p...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.160467
更新日期:2016-11-09 00:00:00
abstract::In this paper, recent progress in graphic statics is combined with Williot displacement diagrams to create a graphical description of both statics and kinematics for two- and three-dimensional pin-jointed trusses. We begin with reciprocal form and force diagrams. The force diagram is dissected into its component cells...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.170202
更新日期:2017-05-24 00:00:00
abstract::Smoking is associated with shorter leucocyte telomere length (LTL), a biomarker of increased morbidity and reduced longevity. This association is widely interpreted as evidence that smoking causes accelerated LTL attrition in adulthood, but the evidence for this is inconsistent. We analysed the association between smo...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.190420
更新日期:2019-06-05 00:00:00
abstract::Arc faults in low-voltage electrical circuits are the main hidden cause of electric fires. Accurate identification of arc faults is essential for safe power consumption. In this paper, a detection algorithm for arc faults is tested in a low-voltage circuit. With capacitance coupling and a logarithmic detector, the hig...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.180160
更新日期:2018-09-19 00:00:00
abstract::[This corrects the article DOI: 10.1098/rsos.191444.]. ...
journal_title:Royal Society open science
pub_type: 已发布勘误
doi:10.1098/rsos.192176
更新日期:2020-01-22 00:00:00
abstract::A novel reference film was characterized to improve the oxygen gas transmission measurement accuracy of plastic materials for pharmaceutical packaging. The material processing, homogeneity, stability, jointly determined value and uncertainty evaluation were discussed. The film is the first reference film characterized...
journal_title:Royal Society open science
pub_type: 杂志文章
doi:10.1098/rsos.190142
更新日期:2019-04-10 00:00:00