The effects of sequencing platforms on phylogenetic resolution in 16 S rRNA gene profiling of human feces.

abstract：:The corneal endothelium maintains corneal transparency; consequently, damage to this endothelium by a number of pathological conditions results in severe vision loss. Publicly available expression databases of human tissues are useful for investigating the pathogenesis of diseases and for developing new therapeutic mo...

journal_title：Scientific data

authors： Tokuda Y,Okumura N,Komori Y,Hanada N,Tashiro K,Koizumi N,Nakano M

更新日期：2020-11-20 00:00:00

abstract：:Transparent evaluations of FAIRness are increasingly required by a wide range of stakeholders, from scientists to publishers, funding agencies and policy makers. We propose a scalable, automatable framework to evaluate digital resources that encompasses measurable indicators, open source tools, and participation guide...

journal_title：Scientific data

authors： Wilkinson MD,Dumontier M,Sansone SA,Bonino da Silva Santos LO,Prieto M,Batista D,McQuilton P,Kuhn T,Rocca-Serra P,Crosas M,Schultes E

更新日期：2019-09-20 00:00:00

abstract：:We provide a detailed description of a gadoteridol-derivatized lysozyme (gadolinium lysozyme) two-colour serial femtosecond crystallography (SFX) dataset for multiple wavelength anomalous dispersion (MAD) structure determination. The data was collected at the Spring-8 Angstrom Compact free-electron LAser (SACLA) facil...

journal_title：Scientific data

authors： Gorel A,Motomura K,Fukuzawa H,Doak RB,Grünbein ML,Hilpert M,Inoue I,Kloos M,Nass Kovács G,Nango E,Nass K,Roome CM,Shoeman RL,Tanaka R,Tono K,Foucar L,Joti Y,Yabashi M,Iwata S,Ueda K,Barends TRM,Schlichting I

更新日期：2017-12-12 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) differentiated into hepatocyte-like cells (HLCs) provide a defined and renewable source of cells for drug screening, toxicology and regenerative medicine. We previously reprogrammed human fetal foreskin fibroblast cells (HFF1) into iPSCs emp...

journal_title：Scientific data

authors： Wruck W,Adjaye J

更新日期：2018-03-13 00:00:00

abstract：:Land-atmosphere interactions at different temporal and spatial scales are important for our understanding of the Earth system and its modeling. The Landscape Evolution Observatory (LEO) at Biosphere 2, managed by the University of Arizona, hosts three nearly identical artificial bare-soil hillslopes with dimensions of...

journal_title：Scientific data

authors： Arevalo J,Zeng X,Durcik M,Sibayan M,Pangle L,Abramson N,Bugaj A,Ng WR,Kim M,Barron-Gafford G,van Haren J,Niu GY,Adams J,Ruiz J,Troch PA

更新日期：2020-09-15 00:00:00

abstract：:We present a test-retest dataset for evaluation of long-term reliability of measures from structural and resting-state functional magnetic resonance imaging (sMRI and rfMRI) scans. The repeated scan dataset was collected from 61 healthy adults in two sessions using highly similar imaging parameters at an interval of 1...

journal_title：Scientific data

authors： Huang L,Huang T,Zhen Z,Liu J

更新日期：2016-03-15 00:00:00

abstract：:In angiogenesis with concurrent inflammation, many pathways are activated, some linked to VEGF and others largely VEGF-independent. Pathways involving inflammatory mediators, chemokines, and micro-RNAs may play important roles in maintaining a pro-angiogenic environment or mediating angiogenic regression. Here, we des...

journal_title：Scientific data

authors： Mukwaya A,Lindvall JM,Xeroudaki M,Peebo B,Ali Z,Lennikov A,Jensen LD,Lagali N

更新日期：2016-11-22 00:00:00

abstract：:Understanding of sequence diversity is the cornerstone of analysis of genetic disorders, population genetics, and evolutionary biology. Here, we present an update of our sequencing set to 15,220 Icelanders who we sequenced to an average genome-wide coverage of 34X. We identified 39,020,168 autosomal variants passing G...

journal_title：Scientific data

authors： Jónsson H,Sulem P,Kehr B,Kristmundsdottir S,Zink F,Hjartarson E,Hardarson MT,Hjorleifsson KE,Eggertsson HP,Gudjonsson SA,Ward LD,Arnadottir GA,Helgason EA,Helgason H,Gylfason A,Jonasdottir A,Jonasdottir A,Rafnar T,Bes

更新日期：2017-09-21 00:00:00

abstract：:Efforts to identify meaningful functional imaging-based biomarkers are limited by the ability to reliably characterize inter-individual differences in human brain function. Although a growing number of connectomics-based measures are reported to have moderate to high test-retest reliability, the variability in data ac...

journal_title：Scientific data

authors： Zuo XN,Anderson JS,Bellec P,Birn RM,Biswal BB,Blautzik J,Breitner JC,Buckner RL,Calhoun VD,Castellanos FX,Chen A,Chen B,Chen J,Chen X,Colcombe SJ,Courtney W,Craddock RC,Di Martino A,Dong HM,Fu X,Gong Q,Gorgolews

更新日期：2014-12-09 00:00:00

abstract：:Larval fishes are a useful metric of marine ecosystem state and change, as well as species-specific patterns in phenology. The high level of taxonomic expertise required to identify larval fishes to species level, and the considerable effort required to collect samples, make these data very valuable. Here we collate 3...

journal_title：Scientific data

authors： Smith JA,Miskiewicz AG,Beckley LE,Everett JD,Garcia V,Gray CA,Holliday D,Jordan AR,Keane J,Lara-Lopez A,Leis JM,Matis PA,Muhling BA,Neira FJ,Richardson AJ,Smith KA,Swadling KM,Syahailatua A,Taylor MD,van Ruth PD,W

更新日期：2018-10-16 00:00:00

abstract：:Although a key driver of Earth's climate system, global land-atmosphere energy fluxes are poorly constrained. Here we use machine learning to merge energy flux measurements from FLUXNET eddy covariance towers with remote sensing and meteorological data to estimate global gridded net radiation, latent and sensible heat...

journal_title：Scientific data

authors： Jung M,Koirala S,Weber U,Ichii K,Gans F,Camps-Valls G,Papale D,Schwalm C,Tramontana G,Reichstein M

更新日期：2019-05-27 00:00:00

abstract：:The experimental dataset presented was collected in an 18 m long and 1 m wide laboratory flume. Low to high flood flows through an urbanized floodplain were modelled. The floodplain bed is rough, modelled with dense artificial grass. A square cylinder array, representing house models, was set on the rough bed. The cyl...

journal_title：Scientific data

authors： Oukacine M,Proust S,Larrarte F,Goutal N

更新日期：2021-01-11 00:00:00

abstract：:Gene-gene (GXG) and gene-environment (GXE) interactions play important roles in pharmacogenetics study. Simultaneously incorporating multiple single nucleotide polymorphisms (SNPs) and clinical factors is needed to explore the association of their interactions with drug response and toxicity phenotypes. We genotyped 5...

journal_title：Scientific data

authors： Wang LY,Cui JJ,Liu JY,Guo AX,Zhao ZY,Liu YZ,Wu JC,Li M,Hu CP,Gao Y,Zhou HH,Yin JY

更新日期：2018-12-11 00:00:00

abstract：:Size-resolved aerosol samples were collected in Metro Manila between July 2018 and October 2019. Two Micro-Orifice Uniform Deposit Impactors (MOUDI) were deployed at Manila Observatory in Quezon City, Metro Manila with samples collected on a weekly basis for water-soluble speciation and mass quantification. Additional...

journal_title：Scientific data

authors： Stahl C,Cruz MT,Bañaga PA,Betito G,Braun RA,Aghdam MA,Cambaliza MO,Lorenzo GR,MacDonald AB,Pabroa PC,Yee JR,Simpas JB,Sorooshian A

更新日期：2020-04-29 00:00:00

abstract：:A comprehensive transcriptome analysis of an expressed sequence tag (EST) database of the spider Dolomedes fimbriatus venom glands using single-residue distribution analysis (SRDA) identified 7,169 unique sequences. Mature chains of 163 different toxin-like polypeptides were predicted on the basis of well-established ...

journal_title：Scientific data

authors： Kozlov SA,Lazarev VN,Kostryukova ES,Selezneva OV,Ospanova EA,Alexeev DG,Govorun VM,Grishin EV

更新日期：2014-08-05 00:00:00

abstract：:Phase contrast time-lapse microscopy is a non-destructive technique that generates large volumes of image-based information to quantify the behaviour of individual cells or cell populations. To guide the development of algorithms for computer-aided cell tracking and analysis, 48 time-lapse image sequences, each spanni...

journal_title：Scientific data

authors： Ker DFE,Eom S,Sanami S,Bise R,Pascale C,Yin Z,Huh SI,Osuna-Highley E,Junkers SN,Helfrich CJ,Liang PY,Pan J,Jeong S,Kang SS,Liu J,Nicholson R,Sandbothe MF,Van PT,Liu A,Chen M,Kanade T,Weiss LE,Campbell PG

更新日期：2018-11-13 00:00:00

abstract：:The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses to gram-negative bacterial infection and its contribution ...

journal_title：Scientific data

authors： Sun J,Katz S,Dutta B,Wang Z,Fraser ID

更新日期：2017-03-01 00:00:00

abstract：:Climate change has already influenced lake temperatures globally, but understanding future change is challenging. The response of lakes to changing climate drivers is complex due to the nature of lake-atmosphere coupling, ice cover, and stratification. To better understand the diversity of lake responses to climate ch...

journal_title：Scientific data

authors： Winslow LA,Hansen GJA,Read JS,Notaro M

更新日期：2017-04-25 00:00:00

abstract：:Disease surveillance systems worldwide face increasing pressure to maintain and distribute data in usable formats supplemented with effective visualizations to enable actionable policy and programming responses. Annual reports and interactive portals provide access to surveillance data and visualizations depicting tem...

journal_title：Scientific data

authors： Simpson RB,Zhou B,Alarcon Falconi TM,Naumova EN

更新日期：2020-10-13 00:00:00

abstract：:Sepsis is a syndrome with physiologic, pathologic, and biochemical abnormalities induced by infection. Sepsis can induce the dysregulation of systemic coagulation and fibrinolytic systems, resulting in disseminated intravascular coagulation (DIC), which is associated with a high mortality rate. Although there is no in...

journal_title：Scientific data

authors： Hayakawa M,Yamakawa K,Saito S,Uchino S,Kudo D,Iizuka Y,Sanui M,Takimoto K,Mayumi T

更新日期：2018-12-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific data

authors： Schweiker M,Abdul-Zahra A,André M,Al-Atrash F,Al-Khatri H,Alprianti RR,Alsaad H,Amin R,Ampatzi E,Arsano AY,Azadeh M,Azar E,Bahareh B,Batagarawa A,Becker S,Buonocore C,Cao B,Choi JH,Chun C,Daanen H,Damiati SA,Dan

更新日期：2020-01-06 00:00:00

abstract：:Lysosomes are the main degradative organelles of cells and involved in a variety of processes including the recycling of macromolecules, storage of compounds, and metabolic signaling. Despite an increasing interest in the proteomic analysis of lysosomes, no systematic study of sample preparation protocols for lysosome...

journal_title：Scientific data

authors： Ponnaiyan S,Akter F,Singh J,Winter D

更新日期：2020-02-26 00:00:00

abstract：:While there is a high interest in drug combinations in cancer therapy, openly accessible datasets for drug combination responses are sparse. Here we present a dataset comprising 171 pairwise combinations of 19 individual drugs targeting signal transduction mechanisms across eight cancer cell lines, where the effect of...

journal_title：Scientific data

authors： Flobak Å,Niederdorfer B,Nakstad VT,Thommesen L,Klinkenberg G,Lægreid A

更新日期：2019-10-29 00:00:00

abstract：:Confident identification of unknown chemicals in high resolution mass spectrometry (HRMS) screening studies requires cohesive workflows and complementary data, tools, and software. Chemistry databases, screening libraries, and chemical metadata have become fixtures in identification workflows. To increase confidence i...

journal_title：Scientific data

authors： McEachran AD,Balabin I,Cathey T,Transue TR,Al-Ghoul H,Grulke C,Sobus JR,Williams AJ

更新日期：2019-08-02 00:00:00

abstract：:Metadata that are structured using principled schemas and that use terms from ontologies are essential to making biomedical data findable and reusable for downstream analyses. The largest source of metadata that describes the experimental protocol, funding, and scientific leadership of clinical studies is ClinicalTria...

journal_title：Scientific data

authors： Miron L,Gonçalves RS,Musen MA

更新日期：2020-12-18 00:00:00

abstract：:Trait-based approaches advance ecological and evolutionary research because traits provide a strong link to an organism's function and fitness. Trait-based research might lead to a deeper understanding of the functions of, and services provided by, ecosystems, thereby improving management, which is vital in the curren...

journal_title：Scientific data

authors： Madin JS,Anderson KD,Andreasen MH,Bridge TC,Cairns SD,Connolly SR,Darling ES,Diaz M,Falster DS,Franklin EC,Gates RD,Harmer A,Hoogenboom MO,Huang D,Keith SA,Kosnik MA,Kuo CY,Lough JM,Lovelock CE,Luiz O,Martinelli J

更新日期：2016-03-29 00:00:00

abstract：:The detection, identification, and localization of illicit nuclear materials in urban environments is of utmost importance for national security. Most often, the process of performing these operations consists of a team of trained individuals equipped with radiation detection devices that have built-in algorithms to a...

journal_title：Scientific data

authors： Ghawaly JM Jr,Nicholson AD,Peplow DE,Anderson-Cook CM,Myers KL,Archer DE,Willis MJ,Quiter BJ

更新日期：2020-10-05 00:00:00

abstract：:One of the many ways that climate change may affect human health is by altering the nutrient content of food crops. However, previous attempts to study the effects of increased atmospheric CO2 on crop nutrition have been limited by small sample sizes and/or artificial growing conditions. Here we present data from a me...

journal_title：Scientific data

authors： Dietterich LH,Zanobetti A,Kloog I,Huybers P,Leakey AD,Bloom AJ,Carlisle E,Fernando N,Fitzgerald G,Hasegawa T,Holbrook NM,Nelson RL,Norton R,Ottman MJ,Raboy V,Sakai H,Sartor KA,Schwartz J,Seneweera S,Usui Y,Yoshina

更新日期：2015-07-21 00:00:00

abstract：:Gait analysis has traditionally relied on laborious and lab-based methods. Data from wearable sensors, such as Inertial Measurement Units (IMU), can be analyzed with machine learning to perform gait analysis in real-world environments. This database provides data from thirty participants (fifteen males and fifteen fem...

journal_title：Scientific data

authors： Luo Y,Coppola SM,Dixon PC,Li S,Dennerlein JT,Hu B

更新日期：2020-07-08 00:00:00

abstract：:East Africa is a drought prone, food and water insecure region with a highly variable climate. This complexity makes rainfall estimation challenging, and this challenge is compounded by low rain gauge densities and inhomogeneous monitoring networks. The dearth of observations is particularly problematic over the past ...

journal_title：Scientific data

authors： Funk C,Nicholson SE,Landsfeld M,Klotter D,Peterson P,Harrison L

更新日期：2015-09-29 00:00:00