Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Sykora-Bodie ST,Bezy V,Johnston DW,Newton E,Lohmann KJdoi
10.1038/s41598-018-24799-wsubject
Has Abstractpub_date
2018-04-19 00:00:00pages
6479issue
1issn
2045-2322pii
10.1038/s41598-018-24799-wjournal_volume
8pub_type
已发布勘误abstract::The vast majority of proteins do not form functional interactions in physiological conditions. We have considered several sets of protein pairs from S. cerevisiae with no functional interaction reported, denoted as non-interacting pairs, and compared their 3D structures to available experimental complexes. We identifi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40419
更新日期:2017-01-13 00:00:00
abstract::We wanted to determine whether subjective sleep disturbance was associated with serum glycated hemoglobin (HbA1c) in people with type 2 diabetes mellitus. In total, 944 randomly-selected people with diabetes completed the Chinese version of the Pittsburgh Sleep Quality Index (PSQI). Participants' glycaemia was assesse...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50814-9
更新日期:2019-10-03 00:00:00
abstract::Nilaparvata lugens (Stål) (Hemiptera: Delphacidae) is a major rice pest that harbors an endosymbiont ascomycete fungus, Entomomyces delphacidicola str. NLU (also known as yeast-like symbiont, YLS). Driving by demand of novel population management tactics (e.g. RNAi), the importance of YLS has been studied and revealed...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42206
更新日期:2017-02-13 00:00:00
abstract::In this paper, we explore the concept of structural Luneburg lens (SLL) as a design framework for performing dynamic structural tailoring to obtain a structural wave cloak and a structural waveguide. The SLL is a graded refractive index lens, which is realized by using a variable thickness structure defined in a thin ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71124-5
更新日期:2020-09-03 00:00:00
abstract::Footprint evidence of human-megafauna interactions remains extremely rare in the archaeological and palaeontological records. Recent work suggests ancient playa environments may hold such evidence, though the prints may not be visible. These so-called "ghost tracks" comprise a rich archive of biomechanical and behavio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52996-8
更新日期:2019-11-11 00:00:00
abstract::Unusual protein-like, partially reversible associative behaviour has recently been observed in solutions of the water soluble carbohydrates known as 6-deoxy-6-(ω-aminoalkyl)aminocelluloses, which produce controllable self-assembling films for enzyme immobilisation and other biotechnological applications. Now, for the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03861
更新日期:2014-01-24 00:00:00
abstract::Ophidian accidents are considered an important neglected tropical disease by the World Health Organization. Particularly in Latin America, Bothrops snakes are responsible for the majority of the snakebite envenomings that are not efficiently treated by conventional serum therapy. Thus, the search for simple and effici...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36839-6
更新日期:2019-01-24 00:00:00
abstract::Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to muscle hypertrophy or double-muscled (DM) phenotype in cattle, sheep, dog and human. However, there has not been reported significant muscle phenotypes in pigs in association with MSTN mutations. Pigs...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14435
更新日期:2015-09-24 00:00:00
abstract::Plutonium and radiocaesium are hazardous contaminants released by the Fukushima Daiichi nuclear power plant (FDNPP) disaster and their distribution in the environment requires careful characterisation using isotopic information. Comprehensive spatial survey of 134Cs and 137Cs has been conducted on a regular basis sinc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34302-0
更新日期:2018-11-14 00:00:00
abstract::Lung adenosquamous cell carcinomas (ASCs) is a rare variant of NSCLC with a poorer prognosis and fewer treatment option than the more common variants. PD-L1 expression is reported to be the predictor of clinical response in trials of NSCLC. In our study, PD-L1 expression was evaluated via immunohistochemistry using a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46209
更新日期:2017-04-07 00:00:00
abstract::Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that class IA PI3K-mediated signals induce the expression of the transcription factor Pax5, which pl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19460-5
更新日期:2018-01-22 00:00:00
abstract::Synthetic analogues of mycobacterial trehalose-dimycolate such as trehalose acyl esters have been proposed as novel adjuvants for vaccination. They induce an immune response by binding to the macrophage C-type lectin receptor Mincle. The binding site of trehalose is known, but there is yet only very limited structural...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23624-8
更新日期:2018-03-29 00:00:00
abstract::Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag, following cataract removal. Standard IOLs allow the anterior and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24453
更新日期:2016-04-14 00:00:00
abstract::Artificially structured coatings are widely employed to minimize materials deterioration and corrosion, the annual direct cost of which is over 3% of the gross domestic product (GDP) for industrial countries. Manufacturing higher performance anticorrosive coatings is one of the most efficient approaches to reduce this...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01177
更新日期:2013-01-01 00:00:00
abstract::Identifying similarities and differences in choice behavior across species is informative about how basic mechanisms give rise to more complex processes. In the present study, we compared pre- and post-choice latencies between rats and humans under two paradigms. In Experiment 1, we used a cued choice paradigm where s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20583
更新日期:2016-02-10 00:00:00
abstract::To resolve the pore-associated bottleneck problem observed in the electrode materials used for ultracapacitors, which inhibits the transport of the electrolyte ions, we designed hierarchically structured activated carbon (HAC) by synthesizing a mesoporous silica template/carbon composite and chemically activating it t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21182
更新日期:2016-02-16 00:00:00
abstract::Relative permeability and capillary pressure are the governing parameters that characterize multiphase fluid flow in porous media for diverse natural and industrial applications, including surface water infiltration into the ground, CO2 sequestration, and hydrocarbon enhanced recovery. Although the drastic effects of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51263-0
更新日期:2019-10-18 00:00:00
abstract::Phagocytosis is a process in which target cells or particles are engulfed and taken up by other cells, typically professional phagocytes; this process is crucial in many physiological processes and disease states. The detection of targets for phagocytosis is directed by a complex repertoire of cell surface receptors. ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38127-9
更新日期:2019-02-13 00:00:00
abstract::Certain bacteria produce iron oxide material assembled with nanoparticles (NPs) that are doped with silicon (Fe:Si ~ 3:1) in ambient environment. Such biogenous iron oxides (BIOX) proved to be an excellent electrode material for lithium-ion batteries, but underlying atomistic mechanisms remain elusive. Here, quantum m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38540-8
更新日期:2019-02-12 00:00:00
abstract::Lytic transglycosylases (LTs) catalyze the non-hydrolytic cleavage of the bacterial cell wall by an intramolecular transacetalization reaction. This reaction is critically and broadly important in modifications of the bacterial cell wall in the course of its biosynthesis, recycling, manifestation of virulence, inserti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22527-y
更新日期:2018-03-07 00:00:00
abstract::At present, there is a growing interest in the study of the neurotropic activity of polyunsaturated fatty acids ethanolamides (N-acylethanolamines). N-docosahexaenoylethanolamine (DHEA, synaptamide) is an endogenous metabolite and structural analogue of anandamide, a widely studied endocannabinoid derived from arachid...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80818-9
更新日期:2021-01-12 00:00:00
abstract::Mortuary practices in human evolution record cognitive, social changes and technological innovations. The Neolithic Revolution in the Levant was a watershed in this domain that has long fascinated the archaeological community. Plaster modelled skulls are well known at Jericho and several other Neolithic sites, and in ...
journal_title:Scientific reports
pub_type: 历史文章,杂志文章
doi:10.1038/srep31053
更新日期:2016-08-09 00:00:00
abstract::STIM1 and Orai1 are the main components of a widely conserved Calcium influx pathway known as store-operated calcium entry (SOCE). STIM1 is a calcium sensor, which oligomerizes and activates Orai channels when calcium levels drop inside the endoplasmic reticulum (ER). The series of molecular rearrangements that STIM1 ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29634
更新日期:2016-07-27 00:00:00
abstract::The study of network topology provides insight into the function and behavior of physical, social, and biological systems. A natural step towards discovering the organizing principles of these complex topologies is to identify a reduced network representation using cohesive subgroups or communities. This procedure oft...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30401-0
更新日期:2018-08-09 00:00:00
abstract::This study was to investigate the association between dietary patterns and rhinitis in primary school children. 1,599 students without rhinitis at baseline survey were selected from a primary school children cohort. Information on food consumption, respiratory symptoms, and confounders was collected using questionnair...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44610
更新日期:2017-03-15 00:00:00
abstract::We propose a deep learning model - Probabilistic Prognostic Estimates of Survival in Metastatic Cancer Patients (PPES-Met) for estimating short-term life expectancy (>3 months) of the patients by analyzing free-text clinical notes in the electronic medical record, while maintaining the temporal visit sequence. In a si...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27946-5
更新日期:2018-07-03 00:00:00
abstract::Hypoplastic left heart syndrome (HLHS) is a fatal congenital heart disease in which the left side of the heart is underdeveloped, impairing the systemic circulation. Underdeveloped left ventricle exerts biomechanical stress on the right ventricle that can progress into heart failure. Genome-wide transcriptome changes ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30896
更新日期:2016-08-03 00:00:00
abstract::Novelty seeking (NS) is a personality trait reflecting excitement in response to novel stimuli. High NS is usually a predictor of risky behaviour such as drug abuse. However, the relationships between NS and risk-related cognitive processes, including individual risk preference and the brain activation associated with...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep10534
更新日期:2015-06-11 00:00:00
abstract::The association between alcohol consumption and kidney function is intriguing, but study results are mixed and controversial. We examined the association of alcohol consumption with the overall change in kidney function over 12 years. We analyzed data from a population-based cohort that was part of the Korean Genome a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81777-5
更新日期:2021-01-27 00:00:00
abstract::Living organisms in drying environments build anisotropic structures and exhibit directionality through self-organization of biopolymers. However, the process of macro-scale assembly is still unknown. Here, we introduce a dissipative structure through a non-equilibrium process between hydration and deposition in the d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05883-z
更新日期:2017-07-21 00:00:00