Abstract:
:Adolescence is a complex period of concurrent mental and physical development that facilitates adult functioning at multiple levels. Despite the growing number of neuroimaging studies of cognitive development in adolescence focusing on regional activation patterns, there remains a paucity of information about the functional interactions across these participating regions that are critical for cognitive functioning, including memory. The current study used structural equation modeling (SEM) to determine how interactions among brain regions critical for memory change over the course of adolescence. We obtained functional MRI in 77 individuals aged 8-16 years old, divided into younger (ages 8-10) and older (ages > 11) cohorts, using an incidental encoding memory task to activate hippocampus formation and associated brain networks, as well as behavioral data on memory function. SEM was performed on the imaging data for four groups (younger girls, younger boys, older girls, and older boys) that were subsequently compared using a stacked model approach. Significant differences were seen between the models for these groups. Younger boys had a predominantly posterior distribution of connections originating in primary visual regions and terminating on multi-modal processing regions. In older boys, there was a relatively greater anterior connection distribution, with increased effective connectivity within association and multi-modal processing regions. Connection patterns in younger girls were similar to those of older boys, with a generally anterior-posterior distributed network among sensory, multi-modal, and limbic regions. In contrast, connections in older girls were widely distributed but relatively weaker. Memory performance increased with age, without a significant difference between the sexes. These findings suggest a progressive reorganization among brain regions, with a commensurate increase in efficiency of cognitive functioning, from younger to older individuals in both girls and boys, providing insight into the age- and gender-specific processes at play during this critical transition period.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Riley JD,Chen EE,Winsell J,Davis EP,Glynn LM,Baram TZ,Sandman CA,Small SL,Solodkin Adoi
10.1016/j.neuroimage.2018.04.013subject
Has Abstractpub_date
2018-07-15 00:00:00pages
402-412eissn
1053-8119issn
1095-9572pii
S1053-8119(18)30303-3journal_volume
175pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::Aberrant patterns of brain functional connectivity in the default mode network (DMN) have been observed across different classes of substance use disorder (SUD) and are associated with craving and relapse. In addicted individuals resting functional connectivity (RSFC) of the anterior DMN, which participates in attribu...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2019.06.036
更新日期:2019-10-15 00:00:00
abstract::In the motion aftereffect (MAE), adapting to a moving stimulus causes a subsequently presented stationary stimulus to appear to move in the opposite direction. Recently, the neural basis of the motion aftereffect has received considerable interest, and a number of brain areas have been implicated in the generation of ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.06.034
更新日期:2013-11-15 00:00:00
abstract::A fundamental component of brain development is the formation of large-scale networks across the cortex. One such network, the default network, undergoes a protracted development, displaying weak connectivity in childhood that strengthens in adolescence and becomes most robust in adulthood. Little is known about the g...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.10.030
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Myelin specific imaging techniques to characterize white matter in demyelinating diseases such as multiple sclerosis (MS) have become an area of increasing focus. Gray matter myelination is an important marker of cortical microstructure, and its impairment is relevant in progressive MS. However, its assessme...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117442
更新日期:2021-01-15 00:00:00
abstract::Model-based analysis methods for fMRI data assume a priori knowledge of the time course of the hemodynamic response (HR) in reaction to experimental stimuli or events. This knowledge is incorporated into the hemodynamic response function (HRF), which is a common model of the HR. Although it is already known that the H...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.06.003
更新日期:2006-09-01 00:00:00
abstract:RATIONAL:The human perirhinal cortex (PRC) plays critical roles in episodic and semantic memory and visual perception. The PRC consists of Brodmann areas 35 and 36 (BA35, BA36). In Alzheimer's disease (AD), BA35 is the first cortical site affected by neurofibrillary tangle pathology, which is closely linked to neural i...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.09.070
更新日期:2017-01-01 00:00:00
abstract::Individuals scoring relatively high on measures of working memory tend to be more proficient at controlling attention to minimize the effect of distracting information. It is currently unknown whether such superior attention control abilities are mediated by stronger suppression of irrelevant information, enhancement ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.05.060
更新日期:2014-10-01 00:00:00
abstract::Race disparities in behavior may emerge in several ways, some of which may be independent of implicit bias. To mitigate the pernicious effects of different race disparities for racial minorities, we must understand whether they are rooted in perceptual, affective, or cognitive processing with regard to race perception...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.02.043
更新日期:2016-05-15 00:00:00
abstract::Models of action selection postulate the critical involvement of the subthalamic nucleus (STN), especially in reactive inhibition processes when inappropriate responses to a sudden stimulus must be overridden. The STN could also play a key role during proactive inhibition, when subjects prepare to potentially suppress...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.10.070
更新日期:2014-05-01 00:00:00
abstract::Obesity is a health problem that has become a major focus of attention in recent years. There is growing evidence of an association between obesity and differences in reward processing. However, it is not known at present whether these differences are linked exclusively to food, or whether they can be detected in othe...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.035
更新日期:2013-02-01 00:00:00
abstract::Over the last few years, several functionally distinct subregions of the posterior parietal cortex (PPC) have been shown to subserve oculomotor control. Since these areas seem to overlap with regions whose activation is related to attention, we used functional magnetic resonance imaging to compare the cerebral activat...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2003.12.039
更新日期:2004-05-01 00:00:00
abstract::Ageing generally leads to impairments in cognitive function and the ability to execute and learn new movements. While the causes of these impairments are often multi-factorial, integrity of the cerebellum in an elderly population is an important predictive factor of both motor function and cognitive function. A simila...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.03.084
更新日期:2015-08-01 00:00:00
abstract::Functional imaging has consistently shown that attention-related areas of medial frontal and posterior parietal cortices are active during the attentional conflict induced by color naming in the presence of distracting words (Stroop task). Such studies, however, have provided few details of the correlational nature be...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.2000.0662
更新日期:2001-01-01 00:00:00
abstract::In an effort to examine the functional neuroanatomy of semantic memory, we studied the relative cerebral blood flow of eight healthy young subjects using 15O-water positron emission tomography (PET). Relative to a visual baseline control condition, each of four visual matching-to-sample tasks activated components of t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0386
更新日期:1999-01-01 00:00:00
abstract::Little is known about the structural brain changes that occur over the first few years of schizophrenia, or how these changes differ from those associated with healthy brain development in adolescence and early adulthood. In this study, we aimed to identify regional differences in grey matter (GM) volume between patie...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.03.041
更新日期:2006-08-15 00:00:00
abstract::There is uncertainty introduced when a cortical surface based model derived from an anatomical MRI is used to reconstruct neural activity with MEG data. This is a specific case of a problem with uncertainty in parameters on which M/EEG lead fields depend non-linearly. Here we present a general mathematical treatment o...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.01.077
更新日期:2012-04-02 00:00:00
abstract::The purpose of this paper is to compare volume- and boundary-based morphometry methods by applying them in the statistical analysis of 2-D shapes. The methods discussed in the first category include voxel-, deformation-, and tensor-based morphometry. The active shape model is demonstrated as an example of the second c...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.12.068
更新日期:2009-04-15 00:00:00
abstract::In this paper, we propose a new automated procedure for lesion identification from single images based on the detection of outlier voxels. We demonstrate the utility of this procedure using artificial and real lesions. The scheme rests on two innovations: First, we augment the generative model used for combined segmen...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.03.028
更新日期:2008-07-15 00:00:00
abstract::Twelve right-handed men performed two mental rotation tasks and two control tasks while whole-head functional magnetic resonance imaging was applied. Mental rotation tasks implied the comparison of different sorts of stimulus pairs, viz. pictures of hands and pictures of tools, which were either identical or mirror im...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2002.1290
更新日期:2002-11-01 00:00:00
abstract::White matter (WM) continues to mature through adolescence in parallel with gains in cognitive ability. To date, developmental changes in human WM microstructure have been inferred using analyses of cross-sectional or two time-point follow-up studies, limiting our understanding of individual developmental trajectories....
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.12.044
更新日期:2014-05-15 00:00:00
abstract::Sensation seeking has been linked to increased risk taking and is therefore crucial in influencing behavioral outcomes of risk-taking behavior. Using functional magnetic resonance imaging (fMRI), the neural underpinnings of risk appraisal were studied in a large subject sample (n=188), stratified according to thrill a...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.09.048
更新日期:2012-02-01 00:00:00
abstract::An amazingly wide range of complex behavior emerges from the cerebral cortex. Much of the information processing that leads to these behaviors is performed in neocortical circuits that span throughout the six layers of the cortex. Maintaining this circuit activity requires substantial quantities of oxygen and energy s...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2017.06.046
更新日期:2019-08-15 00:00:00
abstract::Non-invasive imaging has the potential to play a crucial role in the characterization and translation of experimental animal models to investigate human brain development and disorders, especially when employed to study animal models that more accurately represent features of human neuroanatomy. The purpose of this st...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.03.009
更新日期:2017-05-15 00:00:00
abstract::Simultaneous EEG-fMRI has opened up new avenues for improving the spatio-temporal resolution of functional brain studies. However, this method usually suffers from poor EEG quality, especially for evoked potentials (ERPs), due to specific artifacts. As such, the use of EEG-informed fMRI analysis in the context of cogn...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.05.075
更新日期:2014-10-15 00:00:00
abstract::The aim of this paper is to develop a spatial Gaussian predictive process (SGPP) framework for accurately predicting neuroimaging data by using a set of covariates of interest, such as age and diagnostic status, and an existing neuroimaging data set. To achieve a better prediction, we not only delineate spatial associ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.11.018
更新日期:2014-04-01 00:00:00
abstract::We sought to determine the feasibility of directly studying neural tissue activity by analysis of differential phase shifts in MRI signals that occurred when trickle currents were applied to a bath containing active or resting neural tissue. We developed a finite element bidomain model of an aplysia abdominal ganglion...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.04.005
更新日期:2010-08-01 00:00:00
abstract::The basis for different neural activations in response to male and female voices as well as the question, whether men and women perceive male and female voices differently, has not been thoroughly investigated. Therefore, the aim of the present study was to examine the behavioral and neural correlates of gender-relate...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.04.105
更新日期:2013-10-01 00:00:00
abstract::Our objective was to investigate correlations between clinical motor scores and cerebral sensorimotor activation to demonstrate that this reorganization is the neural substratum of motor recovery. Correlation analyses identified reorganization processes shared by all patients. Nine patients with first-time corticospin...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2003.08.017
更新日期:2003-12-01 00:00:00
abstract::Even after thorough preprocessing and a careful time series analysis of functional magnetic resonance imaging (fMRI) data, artifact and other issues can lead to violations of the assumption that the variance is constant across subjects in the group level model. This is especially concerning when modeling a continuous ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.05.032
更新日期:2017-07-01 00:00:00
abstract::Naturalistic stimuli such as movies are increasingly used to engage cognitive and emotional processes during fMRI of brain hemodynamic activity. However, movies have been little utilized during magnetoencephalography (MEG) and EEG that directly measure population-level neuronal activity at a millisecond resolution. He...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.03.066
更新日期:2015-07-01 00:00:00