Network specialization during adolescence: Hippocampal effective connectivity in boys and girls.

Abstract:

:Adolescence is a complex period of concurrent mental and physical development that facilitates adult functioning at multiple levels. Despite the growing number of neuroimaging studies of cognitive development in adolescence focusing on regional activation patterns, there remains a paucity of information about the functional interactions across these participating regions that are critical for cognitive functioning, including memory. The current study used structural equation modeling (SEM) to determine how interactions among brain regions critical for memory change over the course of adolescence. We obtained functional MRI in 77 individuals aged 8-16 years old, divided into younger (ages 8-10) and older (ages > 11) cohorts, using an incidental encoding memory task to activate hippocampus formation and associated brain networks, as well as behavioral data on memory function. SEM was performed on the imaging data for four groups (younger girls, younger boys, older girls, and older boys) that were subsequently compared using a stacked model approach. Significant differences were seen between the models for these groups. Younger boys had a predominantly posterior distribution of connections originating in primary visual regions and terminating on multi-modal processing regions. In older boys, there was a relatively greater anterior connection distribution, with increased effective connectivity within association and multi-modal processing regions. Connection patterns in younger girls were similar to those of older boys, with a generally anterior-posterior distributed network among sensory, multi-modal, and limbic regions. In contrast, connections in older girls were widely distributed but relatively weaker. Memory performance increased with age, without a significant difference between the sexes. These findings suggest a progressive reorganization among brain regions, with a commensurate increase in efficiency of cognitive functioning, from younger to older individuals in both girls and boys, providing insight into the age- and gender-specific processes at play during this critical transition period.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Riley JD,Chen EE,Winsell J,Davis EP,Glynn LM,Baram TZ,Sandman CA,Small SL,Solodkin A

doi

10.1016/j.neuroimage.2018.04.013

subject

Has Abstract

pub_date

2018-07-15 00:00:00

pages

402-412

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(18)30303-3

journal_volume

175

pub_type

杂志文章
  • Brain default-mode network dysfunction in addiction.

    abstract::Aberrant patterns of brain functional connectivity in the default mode network (DMN) have been observed across different classes of substance use disorder (SUD) and are associated with craving and relapse. In addicted individuals resting functional connectivity (RSFC) of the anterior DMN, which participates in attribu...

    journal_title:NeuroImage

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroimage.2019.06.036

    authors: Zhang R,Volkow ND

    更新日期:2019-10-15 00:00:00

  • Decoding the motion aftereffect in human visual cortex.

    abstract::In the motion aftereffect (MAE), adapting to a moving stimulus causes a subsequently presented stationary stimulus to appear to move in the opposite direction. Recently, the neural basis of the motion aftereffect has received considerable interest, and a number of brain areas have been implicated in the generation of ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.06.034

    authors: Hogendoorn H,Verstraten FA

    更新日期:2013-11-15 00:00:00

  • The impact of serotonin transporter (5-HTTLPR) genotype on the development of resting-state functional connectivity in children and adolescents: a preliminary report.

    abstract::A fundamental component of brain development is the formation of large-scale networks across the cortex. One such network, the default network, undergoes a protracted development, displaying weak connectivity in childhood that strengthens in adolescence and becomes most robust in adulthood. Little is known about the g...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2011.10.030

    authors: Wiggins JL,Bedoyan JK,Peltier SJ,Ashinoff S,Carrasco M,Weng SJ,Welsh RC,Martin DM,Monk CS

    更新日期:2012-02-01 00:00:00

  • Characterization of the cortical myeloarchitecture with inhomogeneous magnetization transfer imaging (ihMT).

    abstract:BACKGROUND:Myelin specific imaging techniques to characterize white matter in demyelinating diseases such as multiple sclerosis (MS) have become an area of increasing focus. Gray matter myelination is an important marker of cortical microstructure, and its impairment is relevant in progressive MS. However, its assessme...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2020.117442

    authors: Munsch F,Varma G,Taso M,Girard O,Guidon A,Duhamel G,Alsop DC

    更新日期:2021-01-15 00:00:00

  • Variability of the BOLD response over time: an examination of within-session differences.

    abstract::Model-based analysis methods for fMRI data assume a priori knowledge of the time course of the hemodynamic response (HR) in reaction to experimental stimuli or events. This knowledge is incorporated into the hemodynamic response function (HRF), which is a common model of the HR. Although it is already known that the H...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2006.06.003

    authors: Menz MM,Neumann J,Müller K,Zysset S

    更新日期:2006-09-01 00:00:00

  • Multi-template analysis of human perirhinal cortex in brain MRI: Explicitly accounting for anatomical variability.

    abstract:RATIONAL:The human perirhinal cortex (PRC) plays critical roles in episodic and semantic memory and visual perception. The PRC consists of Brodmann areas 35 and 36 (BA35, BA36). In Alzheimer's disease (AD), BA35 is the first cortical site affected by neurofibrillary tangle pathology, which is closely linked to neural i...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2016.09.070

    authors: Xie L,Pluta JB,Das SR,Wisse LEM,Wang H,Mancuso L,Kliot D,Avants BB,Ding SL,Manjón JV,Wolk DA,Yushkevich PA

    更新日期:2017-01-01 00:00:00

  • Dissociable mechanisms underlying individual differences in visual working memory capacity.

    abstract::Individuals scoring relatively high on measures of working memory tend to be more proficient at controlling attention to minimize the effect of distracting information. It is currently unknown whether such superior attention control abilities are mediated by stronger suppression of irrelevant information, enhancement ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2014.05.060

    authors: Gulbinaite R,Johnson A,de Jong R,Morey CC,van Rijn H

    更新日期:2014-10-01 00:00:00

  • Dynamic neural mechanisms underlie race disparities in social cognition.

    abstract::Race disparities in behavior may emerge in several ways, some of which may be independent of implicit bias. To mitigate the pernicious effects of different race disparities for racial minorities, we must understand whether they are rooted in perceptual, affective, or cognitive processing with regard to race perception...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2016.02.043

    authors: Cassidy BS,Krendl AC

    更新日期:2016-05-15 00:00:00

  • Subthalamic nucleus activity dissociates proactive and reactive inhibition in patients with Parkinson's disease.

    abstract::Models of action selection postulate the critical involvement of the subthalamic nucleus (STN), especially in reactive inhibition processes when inappropriate responses to a sudden stimulus must be overridden. The STN could also play a key role during proactive inhibition, when subjects prepare to potentially suppress...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.10.070

    authors: Benis D,David O,Lachaux JP,Seigneuret E,Krack P,Fraix V,Chabardès S,Bastin J

    更新日期:2014-05-01 00:00:00

  • Functional connectivity in obesity during reward processing.

    abstract::Obesity is a health problem that has become a major focus of attention in recent years. There is growing evidence of an association between obesity and differences in reward processing. However, it is not known at present whether these differences are linked exclusively to food, or whether they can be detected in othe...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2012.10.035

    authors: García-García I,Jurado MA,Garolera M,Segura B,Marqués-Iturria I,Pueyo R,Vernet-Vernet M,Sender-Palacios MJ,Sala-Llonch R,Ariza M,Narberhaus A,Junqué C

    更新日期:2013-02-01 00:00:00

  • The encoding of saccadic eye movements within human posterior parietal cortex.

    abstract::Over the last few years, several functionally distinct subregions of the posterior parietal cortex (PPC) have been shown to subserve oculomotor control. Since these areas seem to overlap with regions whose activation is related to attention, we used functional magnetic resonance imaging to compare the cerebral activat...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.neuroimage.2003.12.039

    authors: Konen CS,Kleiser R,Wittsack HJ,Bremmer F,Seitz RJ

    更新日期:2004-05-01 00:00:00

  • Ageing shows a pattern of cerebellar degeneration analogous, but not equal, to that in patients suffering from cerebellar degenerative disease.

    abstract::Ageing generally leads to impairments in cognitive function and the ability to execute and learn new movements. While the causes of these impairments are often multi-factorial, integrity of the cerebellum in an elderly population is an important predictive factor of both motor function and cognitive function. A simila...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.03.084

    authors: Hulst T,van der Geest JN,Thürling M,Goericke S,Frens MA,Timmann D,Donchin O

    更新日期:2015-08-01 00:00:00

  • The effect of medial frontal and posterior parietal demyelinating lesions on stroop interference.

    abstract::Functional imaging has consistently shown that attention-related areas of medial frontal and posterior parietal cortices are active during the attentional conflict induced by color naming in the presence of distracting words (Stroop task). Such studies, however, have provided few details of the correlational nature be...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.2000.0662

    authors: Pujol J,Vendrell P,Deus J,Junqué C,Bello J,Martí-Vilalta JL,Capdevila A

    更新日期:2001-01-01 00:00:00

  • Functional neuroanatomy of semantic memory: recognition of semantic associations.

    abstract::In an effort to examine the functional neuroanatomy of semantic memory, we studied the relative cerebral blood flow of eight healthy young subjects using 15O-water positron emission tomography (PET). Relative to a visual baseline control condition, each of four visual matching-to-sample tasks activated components of t...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0386

    authors: Ricci PT,Zelkowicz BJ,Nebes RD,Meltzer CC,Mintun MA,Becker JT

    更新日期:1999-01-01 00:00:00

  • Progressive grey matter atrophy over the first 2-3 years of illness in first-episode schizophrenia: a tensor-based morphometry study.

    abstract::Little is known about the structural brain changes that occur over the first few years of schizophrenia, or how these changes differ from those associated with healthy brain development in adolescence and early adulthood. In this study, we aimed to identify regional differences in grey matter (GM) volume between patie...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2006.03.041

    authors: Whitford TJ,Grieve SM,Farrow TF,Gomes L,Brennan J,Harris AW,Gordon E,Williams LM

    更新日期:2006-08-15 00:00:00

  • A general Bayesian treatment for MEG source reconstruction incorporating lead field uncertainty.

    abstract::There is uncertainty introduced when a cortical surface based model derived from an anatomical MRI is used to reconstruct neural activity with MEG data. This is a specific case of a problem with uncertainty in parameters on which M/EEG lead fields depend non-linearly. Here we present a general mathematical treatment o...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2012.01.077

    authors: López JD,Penny WD,Espinosa JJ,Barnes GR

    更新日期:2012-04-02 00:00:00

  • A comparison of morphometric techniques for studying the shape of the corpus callosum in adolescent idiopathic scoliosis.

    abstract::The purpose of this paper is to compare volume- and boundary-based morphometry methods by applying them in the statistical analysis of 2-D shapes. The methods discussed in the first category include voxel-, deformation-, and tensor-based morphometry. The active shape model is demonstrated as an example of the second c...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2008.12.068

    authors: Wang D,Shi L,Chu WC,Paus T,Cheng JC,Heng PA

    更新日期:2009-04-15 00:00:00

  • Lesion identification using unified segmentation-normalisation models and fuzzy clustering.

    abstract::In this paper, we propose a new automated procedure for lesion identification from single images based on the detection of outlier voxels. We demonstrate the utility of this procedure using artificial and real lesions. The scheme rests on two innovations: First, we augment the generative model used for combined segmen...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2008.03.028

    authors: Seghier ML,Ramlackhansingh A,Crinion J,Leff AP,Price CJ

    更新日期:2008-07-15 00:00:00

  • Motor imagery in mental rotation: an fMRI study.

    abstract::Twelve right-handed men performed two mental rotation tasks and two control tasks while whole-head functional magnetic resonance imaging was applied. Mental rotation tasks implied the comparison of different sorts of stimulus pairs, viz. pictures of hands and pictures of tools, which were either identical or mirror im...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2002.1290

    authors: Vingerhoets G,de Lange FP,Vandemaele P,Deblaere K,Achten E

    更新日期:2002-11-01 00:00:00

  • Developmental stages and sex differences of white matter and behavioral development through adolescence: a longitudinal diffusion tensor imaging (DTI) study.

    abstract::White matter (WM) continues to mature through adolescence in parallel with gains in cognitive ability. To date, developmental changes in human WM microstructure have been inferred using analyses of cross-sectional or two time-point follow-up studies, limiting our understanding of individual developmental trajectories....

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.12.044

    authors: Simmonds DJ,Hallquist MN,Asato M,Luna B

    更新日期:2014-05-15 00:00:00

  • Nothing to lose: processing blindness to potential losses drives thrill and adventure seekers.

    abstract::Sensation seeking has been linked to increased risk taking and is therefore crucial in influencing behavioral outcomes of risk-taking behavior. Using functional magnetic resonance imaging (fMRI), the neural underpinnings of risk appraisal were studied in a large subject sample (n=188), stratified according to thrill a...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2011.09.048

    authors: Kruschwitz JD,Simmons AN,Flagan T,Paulus MP

    更新日期:2012-02-01 00:00:00

  • Vascular density and distribution in neocortex.

    abstract::An amazingly wide range of complex behavior emerges from the cerebral cortex. Much of the information processing that leads to these behaviors is performed in neocortical circuits that span throughout the six layers of the cortex. Maintaining this circuit activity requires substantial quantities of oxygen and energy s...

    journal_title:NeuroImage

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroimage.2017.06.046

    authors: Schmid F,Barrett MJP,Jenny P,Weber B

    更新日期:2019-08-15 00:00:00

  • Population based MRI and DTI templates of the adult ferret brain and tools for voxelwise analysis.

    abstract::Non-invasive imaging has the potential to play a crucial role in the characterization and translation of experimental animal models to investigate human brain development and disorders, especially when employed to study animal models that more accurately represent features of human neuroanatomy. The purpose of this st...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.03.009

    authors: Hutchinson EB,Schwerin SC,Radomski KL,Sadeghi N,Jenkins J,Komlosh ME,Irfanoglu MO,Juliano SL,Pierpaoli C

    更新日期:2017-05-15 00:00:00

  • Single-trial EEG-informed fMRI reveals spatial dependency of BOLD signal on early and late IC-ERP amplitudes during face recognition.

    abstract::Simultaneous EEG-fMRI has opened up new avenues for improving the spatio-temporal resolution of functional brain studies. However, this method usually suffers from poor EEG quality, especially for evoked potentials (ERPs), due to specific artifacts. As such, the use of EEG-informed fMRI analysis in the context of cogn...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2014.05.075

    authors: Wirsich J,Bénar C,Ranjeva JP,Descoins M,Soulier E,Le Troter A,Confort-Gouny S,Liégeois-Chauvel C,Guye M

    更新日期:2014-10-15 00:00:00

  • SGPP: spatial Gaussian predictive process models for neuroimaging data.

    abstract::The aim of this paper is to develop a spatial Gaussian predictive process (SGPP) framework for accurately predicting neuroimaging data by using a set of covariates of interest, such as age and diagnostic status, and an existing neuroimaging data set. To achieve a better prediction, we not only delineate spatial associ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.11.018

    authors: Hyun JW,Li Y,Gilmore JH,Lu Z,Styner M,Zhu H

    更新日期:2014-04-01 00:00:00

  • Can high-field MREIT be used to directly detect neural activity? Theoretical considerations.

    abstract::We sought to determine the feasibility of directly studying neural tissue activity by analysis of differential phase shifts in MRI signals that occurred when trickle currents were applied to a bath containing active or resting neural tissue. We developed a finite element bidomain model of an aplysia abdominal ganglion...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2010.04.005

    authors: Sadleir RJ,Grant SC,Woo EJ

    更新日期:2010-08-01 00:00:00

  • Sex matters: Neural correlates of voice gender perception.

    abstract::The basis for different neural activations in response to male and female voices as well as the question, whether men and women perceive male and female voices differently, has not been thoroughly investigated. Therefore, the aim of the present study was to examine the behavioral and neural correlates of gender-relate...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.04.105

    authors: Junger J,Pauly K,Bröhr S,Birkholz P,Neuschaefer-Rube C,Kohler C,Schneider F,Derntl B,Habel U

    更新日期:2013-10-01 00:00:00

  • Correlation between cerebral reorganization and motor recovery after subcortical infarcts.

    abstract::Our objective was to investigate correlations between clinical motor scores and cerebral sensorimotor activation to demonstrate that this reorganization is the neural substratum of motor recovery. Correlation analyses identified reorganization processes shared by all patients. Nine patients with first-time corticospin...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2003.08.017

    authors: Loubinoux I,Carel C,Pariente J,Dechaumont S,Albucher JF,Marque P,Manelfe C,Chollet F

    更新日期:2003-12-01 00:00:00

  • Reprint of 'A Comprehensive review of group level model performance in the presence of heteroscedasticity: Can a single model control Type I errors in the presence of outliers?'

    abstract::Even after thorough preprocessing and a careful time series analysis of functional magnetic resonance imaging (fMRI) data, artifact and other issues can lead to violations of the assumption that the variance is constant across subjects in the group level model. This is especially concerning when modeling a continuous ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2017.05.032

    authors: Mumford JA

    更新日期:2017-07-01 00:00:00

  • Combined MEG and EEG show reliable patterns of electromagnetic brain activity during natural viewing.

    abstract::Naturalistic stimuli such as movies are increasingly used to engage cognitive and emotional processes during fMRI of brain hemodynamic activity. However, movies have been little utilized during magnetoencephalography (MEG) and EEG that directly measure population-level neuronal activity at a millisecond resolution. He...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.03.066

    authors: Chang WT,Jääskeläinen IP,Belliveau JW,Huang S,Hung AY,Rossi S,Ahveninen J

    更新日期:2015-07-01 00:00:00