Erratum: miR-2478 inhibits TGFβ1 expression by targeting the transcriptional activation region downstream of the TGFβ1 promoter in dairy goats.

abstract：:Bone marrow and adipose tissue represent the two most commonly exploited sources of adult mesenchymal stem cells for musculoskeletal applications. Unfortunately the sampling of bone marrow and fat tissue is invasive and does not always lead to a sufficient number of cells. The present study describes a novel sampling ...

journal_title：Scientific reports

authors： Ceusters J,Lejeune JP,Sandersen C,Niesten A,Lagneaux L,Serteyn D

更新日期：2017-04-06 00:00:00

abstract：:The distribution of carbon from a branch setting pod in alfalfa was investigated during the seed development of seeds to determine the relative contribution of pod and leaf photoassimilates to the total C balance and to investigate the partitioning of these photoassimilates to other plant organs. A 13Clabeling procedu...

journal_title：Scientific reports

authors： Zhang W,Mao P,Li Y,Wang M,Xia F,Wang H

更新日期：2017-02-07 00:00:00

abstract：:MRI of hyperpolarized media, such as (129)Xe and (3)He, shows great potential for clinical applications. The optimal use of the available spin polarization requires accurate flip angle calibrations and T1 measurements. Traditional flip angle calibration methods are time-consuming and suffer from polarization losses du...

journal_title：Scientific reports

authors： Zhong J,Ruan W,Han Y,Sun X,Ye C,Zhou X

更新日期：2016-05-12 00:00:00

abstract：:Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macrophages, smooth muscle cells (SMCs), and endothelial cells from mouse atheroscler...

journal_title：Scientific reports

authors： Liu CL,Santos MM,Fernandes C,Liao M,Iamarene K,Zhang JY,Sukhova GK,Shi GP

更新日期：2017-04-12 00:00:00

abstract：:Panax ginseng (GS) and Veratrum nigrum (VN) are representative of incompatible pairs in "eighteen antagonistic medicaments" that have been recorded in the Chinese medicinal literature for over 2,000 years. However, evidence linking interference effects with combination use is scare. Based on the estrogen-like effect o...

journal_title：Scientific reports

authors： Xu Y,Ding J,An JN,Qu YK,Li X,Ma XP,Zhang YM,Dai GJ,Lin N

更新日期：2016-05-27 00:00:00

abstract：:The neuropeptide oxytocin has been shown to affect social interaction. Meanwhile, the underlying mechanism remains highly debated. Using an interpersonal finger-tapping paradigm, we investigated whether oxytocin affects the ability to synchronise with and adapt to the behaviour of others. Dyads received either oxytoci...

journal_title：Scientific reports

authors： Gebauer L,Witek MAG,Hansen NC,Thomas J,Konvalinka I,Vuust P

更新日期：2016-12-08 00:00:00

abstract：:In the attempt of implementing iron garnets with perpendicular magnetic anisotropy (PMA) in spintronics, the attention turned towards strain-grown iron garnets. One candidate is Tm3Fe5O12 (TmIG) which possesses an out-of-plane magnetic easy axis when grown under tensile strain. In this study, the effect of film thickn...

journal_title：Scientific reports

authors： Ciubotariu O,Semisalova A,Lenz K,Albrecht M

更新日期：2019-11-25 00:00:00

abstract：:Endonuclease V (EndoV) is a ubiquitous protein present in all three kingdoms of life, responsible for the specific cleavages at the second phosphodiester bond 3' to inosine. E. coli EndoV (EcEndoV) is the first member discovered in the EndoV family. It is a small protein with a compact gene organization, yet with a wi...

journal_title：Scientific reports

authors： Zhang Z,Jia Q,Zhou C,Xie W

更新日期：2015-08-05 00:00:00

abstract：:Ursolic acid (UA) has proved to have broad-spectrum anti-tumor effects, but its poor water solubility and incompetent targeting property largely limit its clinical application and efficiency. Here, we synthesized a nanoparticle-based drug carrier composed of chitosan, UA and folate (FA-CS-UA-NPs) and demonstrated that...

journal_title：Scientific reports

authors： Jin H,Pi J,Yang F,Jiang J,Wang X,Bai H,Shao M,Huang L,Zhu H,Yang P,Li L,Li T,Cai J,Chen ZW

更新日期：2016-07-29 00:00:00

abstract：:Experience is an important asset in almost any professional activity. In basketball, there is believed to be a positive association between coaching experience and effective use of team timeouts. Here, we analyze both the extent to which a team's change in scoring margin per possession after timeouts deviate from the ...

journal_title：Scientific reports

authors： Saavedra S,Mukherjee S,Bagrow JP

更新日期：2012-01-01 00:00:00

abstract：:Osteoporosis medication in fragility fracture patients is associated with better outcomes. However, limited studies have investigated whether fracture types affect outcomes among patients undergoing treatment. We performed a secondary data analysis on participants from a fracture liaison service and an osteoporosis me...

journal_title：Scientific reports

authors： Chang CB,Yang RS,Chang LY,Peng JK,Tsai KS,Huang WJ,Yang TH,Chan DC

更新日期：2019-07-12 00:00:00

abstract：:The gradient relationship between mean corpuscular volume (MCV) and mortality due to ischemic vascular disease has not been researched using a large-scale population-based study. This study evaluated the association between MCV and death attributable to cerebrovascular disease (CVD) and cardiovascular disease (CAD) in...

journal_title：Scientific reports

authors： Wu TH,Fann JC,Chen SL,Yen AM,Wen CJ,Lu YR,Chen HH,Chiu SY,Liou HH

更新日期：2018-11-08 00:00:00

abstract：:Prosthesis embodiment, the perception of a prosthesis as part of one's body, may be an important component of functional recovery for individuals with upper limb absence. This work determined whether embodiment differs between body-powered and myoelectric prosthesis users. In a sample of nine individuals with transrad...

journal_title：Scientific reports

authors： Engdahl SM,Meehan SK,Gates DH

更新日期：2020-09-22 00:00:00

abstract：:Gaucher disease (GD) is a rare inherited metabolic disease caused by pathogenic variants in the GBA1 gene. So far, the pathomechanism of GD was investigated mainly in animal models. In order to delineate the molecular changes in GD cells we analysed gene expression profile in cultured skin fibroblasts from GD patients...

journal_title：Scientific reports

authors： Ługowska A,Hetmańczyk-Sawicka K,Iwanicka-Nowicka R,Fogtman A,Cieśla J,Purzycka-Olewiecka JK,Sitarska D,Płoski R,Filocamo M,Lualdi S,Bednarska-Makaruk M,Koblowska M

更新日期：2019-04-15 00:00:00

abstract：:Changes in litterfall dynamics and soil properties due to anthropogenic or natural perturbations have important implications to soil carbon (C) and nutrient cycling via microbial pathway. Here we determine soil microbial responses to contrasting types of litter inputs (leaf vs. fine woody litter) and nitrogen (N) depo...

journal_title：Scientific reports

authors： Sun XL,Zhao J,You YM,Jianxin Sun O

更新日期：2016-01-14 00:00:00

abstract：:We report the synthesis of single-crystal iron germanium nanowires via chemical vapor deposition without the assistance of any catalysts. The assembly of single-crystal FeGe2 nanowires with tetragonal C16 crystal structure shows anisotropic magnetic behavior along the radial direction or the growth axial direction, wi...

journal_title：Scientific reports

authors： Tang S,Kravchenko I,Ward TZ,Zou Q,Yi J,Ma C,Chi M,Cao G,Li AP,Mandrus D,Gai Z

更新日期：2017-08-02 00:00:00

abstract：:For the first time, soil core samples from the Jiuquan region have been analyzed for Pu isotopes for radioactive source identification and radiological assessment. The Jiuquan region is in downwind from the Lop Nor Chinese nuclear test (CNT) site. The high Pu inventories (13 to 546 Bq/m(2)) in most of the sampling loc...

journal_title：Scientific reports

authors： Bu W,Ni Y,Guo Q,Zheng J,Uchida S

更新日期：2015-07-17 00:00:00

abstract：:Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein that controls the cellular response to oxidative stress and possesses DNA-repair functions. It has important roles in the progression and outcomes of various diseases; however, its function and therapeutic prospects with respect to kidney injury ...

journal_title：Scientific reports

authors： Maruyama K,Nakagawa N,Aonuma T,Saito Y,Hayasaka T,Kano K,Horiuchi K,Takehara N,Kawabe JI,Hasebe N

更新日期：2019-05-24 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) are a potential therapy for many chronic inflammatory diseases due to their regenerative, immunologic and anti-inflammatory properties. The two-way dialogue between MSCs and macrophages is crucial to tissue regeneration and repair. Previous research demonstrated that murine adipose-der...

journal_title：Scientific reports

authors： Souza-Moreira L,Soares VC,Dias SDSG,Bozza PT

更新日期：2019-12-30 00:00:00

abstract：:Organometallic trihalide perovskites are promising materials for photovoltaic applications, which have demonstrated a rapid rise in photovoltaic performance in a short period of time. We report a facile one-step method to fabricate planar heterojunction perovskite solar cells by chemical vapor deposition (CVD), with a...

journal_title：Scientific reports

authors： Tavakoli MM,Gu L,Gao Y,Reckmeier C,He J,Rogach AL,Yao Y,Fan Z

更新日期：2015-09-22 00:00:00

abstract：:Tumour tracking is an advanced radiotherapy technique for precise treatment of tumours subject to organ motion. In this work, we addressed crucial aspects of dose delivery for its realisation in pencil beam scanning proton therapy, exploring the momentum acceptance and global achromaticity of a Gantry beamline to perf...

journal_title：Scientific reports

authors： Fattori G,Zhang Y,Meer D,Weber DC,Lomax AJ,Safai S

更新日期：2020-09-18 00:00:00

abstract：:Since it has been demonstrated that spatial cognition can be affected in visually impaired children, training strategies that exploit the plasticity of the human brain should be early adopted. Here we developed and tested a new training protocol based on the reinforcement of audio-motor associations and thus supportin...

journal_title：Scientific reports

authors： Cappagli G,Finocchietti S,Cocchi E,Giammari G,Zumiani R,Cuppone AV,Baud-Bovy G,Gori M

更新日期：2019-03-01 00:00:00

abstract：:Three-dimensional (3D) remote imaging attracts increasing attentions in capturing a target's characteristics. Although great progress for 3D remote imaging has been made with methods such as scanning imaging lidar and pulsed floodlight-illumination imaging lidar, either the detection range or application mode are limi...

journal_title：Scientific reports

authors： Gong W,Zhao C,Yu H,Chen M,Xu W,Han S

更新日期：2016-05-17 00:00:00

abstract：:Natural Bacillus isolates generate limited amounts of surfactin (<10% of their biomass), which functions as an antibiotic or signalling molecule in inter-/intra-specific interactions. However, overproduction of surfactin in Bacillus amyloliquefaciens MT45 was observed at a titre of 2.93 g/l, which is equivalent to hal...

journal_title：Scientific reports

authors： Zhi Y,Wu Q,Xu Y

更新日期：2017-01-23 00:00:00

abstract：:Invasive fungal infections are a potentially life-threatening complication in immunocompromised patients. The aim of this study was to assess the efficacy and safety of posaconazole as compared with other antifungal agents for preventing invasive fungal infections in immunocompromised patients. Embase, CENTRAL, and ME...

journal_title：Scientific reports

authors： Wong TY,Loo YS,Veettil SK,Wong PS,Divya G,Ching SM,Menon RK

更新日期：2020-09-03 00:00:00

abstract：:The natural ligand 17β-estradiol (E2) is so far believed to induce a unique agonist-bound active conformation in the ligand binding domain (LBD) of the estrogen receptors (ERs). Both subtypes, ERα and ERβ, are transcriptionally activated in the presence of E2 with ERβ being somewhat less active than ERα under similar ...

journal_title：Scientific reports

authors： Souza PCT,Textor LC,Melo DC,Nascimento AS,Skaf MS,Polikarpov I

更新日期：2017-06-14 00:00:00

abstract：:The human sweet taste receptor (T1R2) monomer-a member of the G-protein coupled receptor family that detects a wide variety of chemically and structurally diverse sweet tasting molecules, is known to pose a significant threat to human health. Protein that lack crystal structure is a challenge in structure-based protei...

journal_title：Scientific reports

authors： Arodola OA,Kanchi S,Hloma P,Bisetty K,Asiri AM,Inamuddin

更新日期：2020-10-27 00:00:00

abstract：:Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting as white and 789 controls (65.6% white). The results were corrected for populati...

journal_title：Scientific reports

authors： Gomes KF,Santos AS,Semzezem C,Correia MR,Brito LA,Ruiz MO,Fukui RT,Matioli SR,Passos-Bueno MR,Silva ME

更新日期：2017-03-06 00:00:00

abstract：:The aim of this study was to estimate the incidence of T2DM in three population groups: rural, rural-to-urban migrants and urban dwellers. Data from the PERU MIGRANT Study was analysed. The baseline assessment was conducted in 2007-2008 using a single-stage random sample and further follow-up was undertaken in 2015-16...

journal_title：Scientific reports

authors： Ruiz-Alejos A,Carrillo-Larco RM,Miranda JJ,Anderson CAM,Gilman RH,Smeeth L,Bernabé-Ortiz A

更新日期：2018-04-03 00:00:00

abstract：:MicroRNAs (miRNAs) are important post-transcriptional regulators involved in animal adipogenesis, however, their roles in bovine fat deposition remain poorly understood. In the present study, we conducted a comparative RNA sequencing to identify the key miRNAs involved in beef lipid accumulation by comparing the backf...

journal_title：Scientific reports

authors： Guo Y,Zhang X,Huang W,Miao X

更新日期：2017-03-08 00:00:00