Abstract:
:Teleost fish exhibit a remarkable diversity in the control of sex determination, offering the opportunity to identify novel differentiation mechanisms and their ecological consequences. Here, we perform GWAS using 4715 fish and 46,501 SNP to map sex determination to three separate genomic locations in Atlantic salmon (Salmo salar). To characterize each, whole genome sequencing was performed to 30-fold depth of coverage using 20 fish representing each of three identified sex lineages. SNP polymorphism reveals male fish carry a single copy of the male specific region, consistent with an XX/XY or male heterogametric sex system. Haplotype analysis revealed deep divergence between the putatively ancestral locus on chromosome 2, compared with loci on chromosomes 3 and 6. Haplotypes in fish carrying either the chromosome 3 or 6 loci were nearly indistinguishable, indicating a founding event that occurred following the speciation event that defined Salmo salar from other salmonids. These findings highlight the evolutionarily fluid state of sex determination systems in salmonids, and resolve to the sequence level differences in animals with divergent sex lineages.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Kijas J,McWilliam S,Naval Sanchez M,Kube P,King H,Evans B,Nome T,Lien S,Verbyla Kdoi
10.1038/s41598-018-23984-1subject
Has Abstractpub_date
2018-04-04 00:00:00pages
5664issue
1issn
2045-2322pii
10.1038/s41598-018-23984-1journal_volume
8pub_type
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