Abstract:
:Genome rearrangements have played an important role in the evolution of Yersinia pestis from its progenitor Yersinia pseudotuberculosis. Traditional phylogenetic trees for Y. pestis based on sequence comparison have short internal branches and low bootstrap supports as only a small number of nucleotide substitutions have occurred. On the other hand, even a small number of genome rearrangements may resolve topological ambiguities in a phylogenetic tree. We reconstructed phylogenetic trees based on genome rearrangements using several popular approaches such as Maximum likelihood for Gene Order and the Bayesian model of genome rearrangements by inversions. We also reconciled phylogenetic trees for each of the three CRISPR loci to obtain an integrated scenario of the CRISPR cassette evolution. Analysis of contradictions between the obtained evolutionary trees yielded numerous parallel inversions and gain/loss events. Our data indicate that an integrated analysis of sequence-based and inversion-based trees enhances the resolution of phylogenetic reconstruction. In contrast, reconstructions of strain relationships based on solely CRISPR loci may not be reliable, as the history is obscured by large deletions, obliterating the order of spacer gains. Similarly, numerous parallel gene losses preclude reconstruction of phylogeny based on gene content.
journal_name
PeerJjournal_title
PeerJauthors
Bochkareva OO,Dranenko NO,Ocheredko ES,Kanevsky GM,Lozinsky YN,Khalaycheva VA,Artamonova II,Gelfand MSdoi
10.7717/peerj.4545subject
Has Abstractpub_date
2018-03-27 00:00:00pages
e4545issn
2167-8359pii
4545journal_volume
6pub_type
杂志文章相关文献
PeerJ文献大全abstract::This article describes or redescribes four hexactinellid sponges, namely Poliopogon amadou, Euplectella sanctipauli sp. nov., Bolosoma perezi sp. nov. and Advhena magnifica gen. et sp. nov. P. amadou, E. sanctipauli sp. nov. and B. perezi sp. nov. represent new findings for the South Atlantic deep-sea fauna, including...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9431
更新日期:2020-07-09 00:00:00
abstract::Background. The gram-negative Neisseria is associated with two of the most potent human epidemic diseases: meningococcal meningitis and gonorrhoea. In both cases, disease is caused by bacteria colonizing human mucosal membrane surfaces. Overall, the genus shows great diversity and genetic variation mainly due to its a...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1698
更新日期:2016-03-17 00:00:00
abstract:Background:Silkworm pupae is the main by-product of the sericulture industry with an interesting nutritional profile, especially in terms of proteins. In consideration of its possible use as a food or food ingredient in Western countries, a comparative proteomic experiment has been performed to investigate the differen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6723
更新日期:2019-06-12 00:00:00
abstract:Background:Dengue is a major and rapidly increasing public health problem. In Argentina, the southern extreme of its distribution in the Americas, epidemic transmission takes place during the warm season. Since its re-emergence in 1998 two major outbreaks have occurred, the biggest during 2016. To identify the environm...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5196
更新日期:2018-07-17 00:00:00
abstract::There has been an increase in the mortality rate and morbidity of kidney cancer (KC) with kidney renal clear cell carcinoma (KIRC) being the most common subtype of KC. GRAMD1C (GRAM Domain Containing 1C) has not been reported to relate to prognosis and immunotherapy in any cancers. Using bioinformatics methods, we jud...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8205
更新日期:2019-12-20 00:00:00
abstract::Mollusc shells are an abundant resource that have been long used to predict the structures of ancient ecological communities, examine evolutionary processes, reconstruct paleoenvironmental conditions, track and predict responses to climatic change, and explore the movement of hominids across the globe. Despite the ubi...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9420
更新日期:2020-07-30 00:00:00
abstract::Wildlife biologists often use grid-based designs to sample animals and generate abundance estimates. Although sampling in grids is theoretically sound, in application, the method can be logistically difficult and expensive when sampling elusive species inhabiting extensive areas. These factors make it challenging to s...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.227
更新日期:2013-12-17 00:00:00
abstract::In this study, we propose and test a novel ensemble method for improving the accuracy of each method in flood susceptibility mapping using evidential belief function (EBF) and support vector machine (SVM). The outcome of the proposed method was compared with the results of each method. The proposed method was implemen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7653
更新日期:2019-10-09 00:00:00
abstract::The mature spermatozoa of Stephanostomum murielae and Stephanostomoides tenuis are described by transmission electron microscopy. They present several ultrastructural features previously reported in other digeneans. Their spermatozoa possess two axonemes of different length showing the 9 + '1' trepaxonematan pattern, ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.744
更新日期:2015-02-12 00:00:00
abstract::Evolutionary biology has entered an era of unprecedented amounts of DNA sequence data, as new sequencing technologies such as Massive Parallel Sequencing (MPS) can generate billions of nucleotides within less than a day. The current bottleneck is how to efficiently handle, process, and analyze such large amounts of da...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5175
更新日期:2018-07-13 00:00:00
abstract::Individual movement influences the spatial and social structuring of a population. Animals regularly use the same paths to move efficiently to familiar places, or to patrol and mark home ranges. We found that Australian sleepy lizards (Tiliqua rugosa), a monogamous species with stable pair-bonds, repeatedly used the s...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1844
更新日期:2016-03-22 00:00:00
abstract::Species interactions are a key component of ecosystems but we generally have an incomplete picture of who-eats-who in a given community. Different techniques have been devised to predict species interactions using theoretical models or abundances. Here, we explore the K nearest neighbour approach, with a special empha...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3644
更新日期:2017-08-10 00:00:00
abstract:Background:Fruit consumption is currently considered beyond the nutritional aspects because of the important roles in disease prevention and benefits to health. The objective of this study was to characterize the chemical profile and evaluate the antioxidant and antimicrobial properties of different fractions obtained ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5991
更新日期:2018-11-28 00:00:00
abstract::In contrast to reports of wild primates, studies of captive primates' flexibility often reveal conservatism: individuals are unable to switch to new and more efficient strategies when task demands change. We propose that such conservatism might be a result of task design and hypothesize that conservatism might be link...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6195
更新日期:2019-01-08 00:00:00
abstract::In this study, four experimental assays were conducted to evaluate the use of a new silver nanoparticle formulation named Argovit-4, which was prepared with slight modifications to enhance its biological activity against white spot syndrome virus (WSSV) in shrimp culture. The goals of these assays were to (1) determin...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8446
更新日期:2020-02-27 00:00:00
abstract:Background:Biopesticides based on strains of the bacterium Bacillus thuringiensis (Bt) are used globally for effective and environmentally friendly pest control. The most serious threat to the sustainable use of these microbial pesticides is the development of resistance on targeted pests. Populations of Plutella xylos...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7535
更新日期:2019-08-23 00:00:00
abstract::Background. A large proportion of natural grasslands around the world is exposed to overgrazing resulting in land degradation and biodiversity loss. Although there is an increasing effort in the promotion of sustainable livestock management, rangeland degradation still occurs because animals' foraging behaviour is hig...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2152
更新日期:2016-06-21 00:00:00
abstract::Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensu...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.452
更新日期:2014-06-24 00:00:00
abstract::The ichthyoplankton assemblage structure in the Yangtze Estuary was analyzed based on four springs in 1999, 2001, 2004 and 2007 in order to provide detailed characterizations of the ichthyoplankton assemblage in springs, examine the long-term dynamics of spring ichthyoplankton assemblages, and evaluate the influence o...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1186
更新日期:2015-08-18 00:00:00
abstract::Background. Neonatal hyperbilirubinemia (HB) may cause severe neurological damage, but serious consequences are effectively controlled by phototherapy and blood exchange transfusion. HB is still a serious health problem in economically compromised parts of the world. The long term outcome has been regarded favorable b...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.294
更新日期:2014-03-04 00:00:00
abstract:Background:Circadian genes have been suggested to play an important role in lung pathology. However, it remains unknown whether polymorphisms of these genes are associated with chronic obstructive pulmonary disease (COPD). Here, we aimed to investigate the association of circadian genes polymorphisms with COPD in a cas...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9806
更新日期:2020-08-27 00:00:00
abstract:Background:The meat quality of yellow feathered broilers is better than the quality of its production. Growth traits are important in the broiler industry. The exploration of regulation mechanisms for the skeletal muscle would help to increase the growth performance of chickens. At present, some progress has been made ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8950
更新日期:2020-04-15 00:00:00
abstract:INTRODUCTION:The aim of this study was to determine the incidence rates of endometrial hyperplasia (EH) and endometrial cancer (EC) in the Republic of Korea using national insurance claim data generated from 2009 to 2012. MATERIALS AND METHODS:Data that were generated from 2009 to 2012 were sourced from the Korean Hea...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2374
更新日期:2016-08-24 00:00:00
abstract:Background:Dry eye disease (DED), a chronic ocular disease, is associated with numerous medical issues, including asthma. However, studies on these associations are limited. In this study, we investigated the incidence of DED among patients with asthma and its correlation with other allergic comorbidities. Methods:We ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5941
更新日期:2018-12-05 00:00:00
abstract::We investigate the survivorship, growth and diet preferences of hatchery-raised juvenile urchins, Tripneustes gratilla, to evaluate the efficacy of their use as biocontrol agents in the efforts to reduce alien invasive algae. In flow-through tanks, we measured urchin growth rates, feeding rates and feeding preferences...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1235
更新日期:2015-09-15 00:00:00
abstract::It has been reported that fermented products (FPs) prepared from sweet potato-shochu distillery by-product suppressed weight gain and decreased serum cholesterol levels in mice under normal dietary conditions. Furthermore, from the information gained from the above data regarding health benefits of the FPs, the aim of...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7671
更新日期:2019-09-12 00:00:00
abstract::Circular RNA (circRNA) is an endogenous noncoding RNA with a covalently closed cyclic structure. Based on their components, circRNAs are divided into exonic circRNAs, intronic circRNAs, and exon-intron circRNAs. CircRNAs have well-conserved sequences and often have high stability due to their resistance to exonuclease...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5503
更新日期:2018-08-24 00:00:00
abstract::The maximum likelihood estimation (MLE) method, typically used for polytomous logistic regression, is prone to bias due to both misclassification in outcome and contamination in the design matrix. Hence, robust estimators are needed. In this study, we propose such a method for nominal response data with continuous cov...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.467
更新日期:2014-07-01 00:00:00
abstract:Background and Aims:The link between gut microbiota and type 2 diabetes (T2D) has been addressed by numerous studies. Streptococcus thermophilus from fermented milk products, has been used as a probiotic in previous research. However, whether heat-killed S. thermophilus can improve the glycemic parameters of diabetic r...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7117
更新日期:2019-06-13 00:00:00
abstract::Several data loggers deployed to monitor temperature and humidity of Crocodylus acutus (American crocodile) nests in South Florida could not be located after hatching. One badly damaged data logger was retrieved, providing insight into the possible fate of the others. Using a taphonomic approach, we identified numerou...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8577
更新日期:2020-02-17 00:00:00