Can the world's favorite fruit, tomato, provide an effective biosynthetic chassis for high-value metabolites?

Abstract:

:Tomato has a relatively short growth cycle (fruit ready to pick within 65-85 days from planting) and a relatively high yield (the average for globe tomatoes is 3-9 kg fruit per plant rising to as much as 40 kg fruit per plant). Tomatoes also produce large amounts of important primary and secondary metabolites which can serve as intermediates or substrates for producing valuable new compounds. As a model crop, tomato already has a broad range of tools and resources available for biotechnological applications, either increased nutrients for health-promoting biofortified foods or as a production system for high-value compounds. These advantages make tomato an excellent chassis for the production of important metabolites. We summarize recent achievements in metabolic engineering of tomato and suggest new candidate metabolites which could be targets for metabolic engineering. We offer a scheme for how to establish tomato as a chassis for industrial-scale production of high-value metabolites.

journal_name

Plant Cell Rep

journal_title

Plant cell reports

authors

Li Y,Wang H,Zhang Y,Martin C

doi

10.1007/s00299-018-2283-8

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

1443-1450

issue

10

eissn

0721-7714

issn

1432-203X

pii

10.1007/s00299-018-2283-8

journal_volume

37

pub_type

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