Abstract:
:The application of molecular genetic approaches with oral mutans streptococci has resulted in the isolation of several genes which may be involved in the cariogenicity of these organisms. Among these are genes coding for cell surface proteins, sucrose metabolizing enzymes, and glycosyltransferase activities. The isolated genes have been utilized to create specific mutants of Streptococcus mutans to assess the potential roles of the gene products in cariogenicity both in vitro and in vivo. These approaches should prove useful in answering some still unresolved questions at the molecular level regarding the cariogenic properties of the organisms.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Kuramitsu HKdoi
10.1007/BF00149733subject
Has Abstractpub_date
1987-09-01 00:00:00pages
257-60issue
3eissn
0393-2990issn
1573-7284journal_volume
3pub_type
杂志文章abstract::The objective was to determine the prevalence of hepatitis B virus (HBV) infection in long-stay institutionalized mentally handicapped adults and to develop a vaccination programme for them. The study was carried out in 1994. The subjects were 171 mentally handicapped adults aged 37-76 (median age 56) with a median ho...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1026793900057
更新日期:2000-01-01 00:00:00
abstract::A total of 541 cases of cholera were observed between May 7 and July 19, 1985 among the 9,929 displaced persons present in a refugee camp in Africa. In spite of malnutrition and other diseases affecting this population, only 12 deaths occurred. Antiepidemic measures consisted of preparation of isolation-wards, treatme...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00144757
更新日期:1988-06-01 00:00:00
abstract::This hospital-based case-control study was designed to investigate the association of low dietary vitamin A and beta carotene consumption with epidermoid lung cancer. Cases were patients with histologically confirmed epidermoid lung cancer diagnosed in six selected hospitals of southwestern France in 1983-84. Controls...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00150430
更新日期:1990-09-01 00:00:00
abstract::We examined the associations between 21 single nucleotide polymorphisms (SNPs) of eight lipid metabolism genes and lipid levels in a Chinese population. This study was conducted as part of a population-based study in China with 799 randomly selected healthy residents who provided fasting blood and an in-person intervi...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-009-9402-3
更新日期:2009-01-01 00:00:00
abstract::To examine whether a low socio-economic status (SES) is an additional risk factor for glucose intolerance in Hong Kong Chinese with known risk factors for glucose intolerance, a total of 2847 Chinese subjects (473 men and 2374 women) were recruited from the community for assessment. They had known risk factors for glu...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1017935707807
更新日期:2001-01-01 00:00:00
abstract::The two best known approaches to predicting cardiovascular risk are Framingham and QRISK. Both methods correctly predict less than 70% of cases, with a high ratio of false positive predictions to true predictions. Each uses a combination of predictors that is applied to the data only once. The present approach uses th...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-011-9634-x
更新日期:2011-12-01 00:00:00
abstract::Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses on the association between cardiovascular mortality in Switzerland and the three major transportation noise sources-road...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-017-0234-2
更新日期:2017-04-01 00:00:00
abstract::The objective of this study was to evaluate the association between number of missing teeth and all cause, cardiovascular, and cancer mortality as well as morbidity and to explore whether socio-economic factors mediate this association. An ongoing prospective cohort study of 1462 Swedish women included a dental survey...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-004-5961-5
更新日期:2005-01-01 00:00:00
abstract::We studied HBV infection in 34 HIV-2-infected patients followed-up in Marseilles. Ten (29%) patients were chronically-infected with HBV, which represents a three-times higher rate than in HIV-1-infected patients in Europe. HBV occult infection was diagnosed in two patients. HBV genotype E was found in seven patients; ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-006-9039-4
更新日期:2006-01-01 00:00:00
abstract::In an effort to find an indicator for use in studies of the epidemiological impact of drug abuse in California in the late 1960s, we recognized that, for comparative analyses, cause specific mortality was less attractive than total mortality of the population group principally affected, young adults. This paper examin...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00419492
更新日期:1986-12-01 00:00:00
abstract::The purpose of this study is to investigate whether there is an association between exercise participation and self-rated health and whether this association can be explained by common genes and/or common environmental influences. In a sample of 5,140 Dutch adult twins and their non-twin siblings from 2,831 families, ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-006-9088-8
更新日期:2007-01-01 00:00:00
abstract::The aim of the study was to assess the performance of weight related nutritional markers [reported involuntary weight loss (WL) greater than 10%, measured WL and body mass index (BMI)] in predicting survival at AIDS stage. The three anthropometric indices were used as time dependent variables in Cox models to predict ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007696530440
更新日期:2000-01-01 00:00:00
abstract::An unmatched, hospital-based case-control study was performed, to determine, whether respiratory syncytial virus (RSV) etiology in hospitalized young children can be predicted clinically. Children under 2 years of age admitted with a lower respiratory tract infection in three hospitals in northern Germany were include...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1024213400297
更新日期:2003-01-01 00:00:00
abstract::Increased fibroblast growth factor 23 (FGF23) concentrations have emerged as a novel risk factor for heart failure and stroke but not for myocardial infarction (MI). Yet, most studies on MI were conducted in coronary artery disease (CAD) patients and the elderly. Evidence is unclear in subjects without CAD and for str...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-014-9982-4
更新日期:2015-02-01 00:00:00
abstract::The peritoneal macrophages from mice on a lipidic diet have shown an increase of surface hydrophobicity of cytoplasmatic membrane. This fact is correlated with a decrease of the phagocytic index and with an impairment of Salmonella typhimurium. ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00157023
更新日期:1986-06-01 00:00:00
abstract::Insulin resistance, low HDL-cholesterol and microalbuminuria are important components of the metabolic syndrome as defined by WHO. Insulin resistance and low HDL-cholesterol are also common in chronic kidney disease (CKD), but it is not clear whether they are early or late phenomenons in the development of renal failu...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-007-9164-8
更新日期:2007-01-01 00:00:00
abstract::The last case of poliomyelitis due to transmission of indigenous wild poliovirus occurred in Italy in 1982. To achieve the certification of the eradication of poliomyelitis in Italy, an active surveillance of acute flaccid paralysis (AFP) in the population aged less than 15 years was set up following the World Health ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007697421114
更新日期:1999-09-01 00:00:00
abstract::Five-hundred-seventy-seven, 6 year old schoolchildren from Rome were examined. 67.8% of them harboured 1 x 10(5) or more Streptococcus mutans CFU per milliliter of saliva. This value was higher than values reported by other Authors. However, the caries prevalence of the subjects in this study was lower than values sho...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007333102815
更新日期:1997-01-01 00:00:00
abstract::EUROCAT Northern Netherlands registers children born with a birth defect in the Northern Netherlands. Data used to be collected via a notification form, which is filled out by the notifier and, if necessary, completed by the general practitioner. To increase the amount of information, EUROCAT started using new methodo...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007656619529
更新日期:2000-04-01 00:00:00
abstract::Exposed to sewage workers of a wastewater treatment plant and a control group in Thessaloniki, Greece, were examined for antibodies against hepatitis A (anti-HAV) and hepatitis B virus (HBV) infection markers. The main objective of this study was to investigate for epidemiological evidence so as to recommend vaccinati...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/b:ejep.0000020444.64546.3b
更新日期:2004-01-01 00:00:00
abstract::Obstetric and neonatal complications have been associated with completed and attempted suicide (suicidal acts) in young offspring. Maternal smoking is one of the most important risk factors for obstetric complications, but the association between prenatal smoking exposure and offspring risk of suicidal acts is unknown...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-011-9556-7
更新日期:2011-06-01 00:00:00
abstract::The aim of the study was to evaluate the relationship between marital status and blood pressure, and to assess the risk of hypertension in adult Polish men, after adjustment for BMI. Material comprised the data of 2,271 healthy men, aged 25-60, occupationally active inhabitants of Wroclaw (south-western Poland). Arter...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-1752-x
更新日期:2005-01-01 00:00:00
abstract::A seroprevalence survey of antibodies to HCV was carried out among 2788 hemodialysis (HD) patients in a region of central Italy. Anti-HCV seroprevalence was 28.6%. A multivariate analysis of risk factors showed a significant association with time on HD, history of blood transfusion and metropolitan area of residence. ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007592912010
更新日期:1999-01-01 00:00:00
abstract::Prenatal famine exposure has previously been shown to be associated with cardiovascular disease and type II diabetes in adulthood. In the current study, we could not demonstrate an effect of prenatal exposure to famine in 2254 term singletons born during the 1944-1945 Dutch famine on adult mortality up to the age of 5...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-7921-0
更新日期:2005-01-01 00:00:00
abstract::To assess whether two inflammatory markers, C-reactive protein (CRP) and interleukin-6 (IL-6), and change in their concentrations over 12 years, are associated with lung function (FVC and FEV(1)) 12 years after baseline. Data are from over 1,500 participants free from self-reported respiratory problems in a large-scal...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-010-9526-5
更新日期:2011-02-01 00:00:00
abstract::Multilevel analysis is today considered a more appropriate way to monitor health care performance, as it allows a less biased estimation of uncertainty, and can also separate and quantify contextual (as opposed to individual) effects. Multilevel analysis should be applied as the standard methodology for hospital compa...
journal_title:European journal of epidemiology
pub_type: 评论,信件
doi:10.1007/s10654-005-2065-9
更新日期:2005-01-01 00:00:00
abstract::Neuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setting. In 1995 and 199...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-011-9624-z
更新日期:2011-10-01 00:00:00
abstract::Seven cases of watery diarrhea of explosive onset, three of them ending within two weeks, are discussed. The cause of diarrhea is believed to be the presence of an organism called Cyanobacteriumlike organism. These are non-refractile, spherical bodies, 8-9 micrometers in diameter, which take on a faint to deep pink co...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01720300
更新日期:1995-12-01 00:00:00
abstract::A study on the characteristics of alcoholics attending the "Alcoholics in treatment" clubs, a community and family-oriented programme against alcoholism, has been conducted in the Friuli-Venezia Giulia region, Northeastern Italy. A total of 598 individuals (93% of those contacted) completed the questionnaire, 431 (72%...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00146371
更新日期:1992-07-01 00:00:00
abstract::We describe a Dot-ELISA system for the rapid, specific and reliable assessment of a subject's antitetanus immune status. The conditions for Dot-ELISA were selected to give positive reactions only for sera with antitetanus antibody titers equal to or higher than 0.06 I.U./ml, considered to represent protection when usi...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00145053
更新日期:1989-03-01 00:00:00