当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Preparation and characterization of contact active antibacterial surface based on chemically modified nanofibrillated cellulose by phenanthridinium silane salt.

Preparation and characterization of contact active antibacterial surface based on chemically modified nanofibrillated cellulose by phenanthridinium silane salt.

Abstract：

:The main object of this research is chemical modification of the nanofibrillated cellulose (NFC) surface with a phenanthridinium silane salt to develop durable non-leaching antibacterial surface. Initially, (3-trimethoxysilylpropyl) phenanthridinium iodide (TMSPhI) as an antibacterial agent was synthesized using (3-chloropropyl trimethoxysilane) (CPTMS) and phenanthridine in the presence of potassium iodide. Subsequently, NFC was cationized by reaction of its hydroxyl groups with the trimethoxysilane group of TMSPhI to prepare the modified sample (NFC-TMSPhI). The synthesized TMSPhI was characterized by FT-IR, 1H and 13C NMR spectroscopies. The modified NFC samples were also characterized by FE-SEM/EDX, XRD, TGA, elemental analysis, contact angle measurement, FT-IR, UV-Visible and fluorescence spectroscopies. The obtained NFC-TMSPhI samples presented fluorescence property at the maximum emission wavelength in the range of 539-549 nm. Additionally, the antibacterial activity of the modified samples were evaluated quantitatively against Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria. All the modified samples displayed promising results with at least bacteriostatic effect or bactericidal properties. Finally, the cytotoxic effect of the modified sample on human dermal fibroblasts (HDFs) and two cancer cell lines (MCF-7 and Hela) was investigated that showed dose- and surface charge-dependent toxicity.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Hassanpour A,Asghari S,Mansour Lakouraj M,Mohseni M

doi

10.1016/j.ijbiomac.2018.03.141

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

528-539

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(18)30214-9

journal_volume

115

pub_type

杂志文章

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