F463L increases the potential of dofetilide on human ether-a-go-go-related gene (hERG) channels.

abstract：:The apolipoprotein E (apoE) epsilon4 allele increases risk of Alzheimer's disease (AD), perhaps by accelerating plaque formation, or by impairing neuron repair. Considerable evidence supports both mechanisms. AD patients with epsilon4 have more and earlier amyloid deposits than do patients without epsilon4. The same i...

journal_title：Microscopy research and technique

authors： Baum L,Chen L,Ng HK,Pang CP

更新日期：2000-08-15 00:00:00

abstract：:Worldwide, breast cancer (BrCa) is currently the leading cause of deaths associated to malignant lesions in adult women. Given that some studies have mentioned that peritumoral adipocytes may contribute to breast carcinogenesis, present work sought to quantitative evaluate the morphometry of these cells in a group of ...

journal_title：Microscopy research and technique

authors： Suárez-Nájera LE,Chanona-Pérez JJ,Valdivia-Flores A,Marrero-Rodríguez D,Salcedo-Vargas M,García-Ruiz DI,Castro-Reyes MA

更新日期：2018-02-01 00:00:00

abstract：:All termite species (Isoptera) are eusocial. These insects live in societies where the division of labor is a predominant characteristic, conditioned by the presence of castes with different morphology, ontogeny, and development. The soldier caste is unique among social insects and it is responsible for colony defense...

journal_title：Microscopy research and technique

authors： Santos CA,Costa-Leonardo AM

更新日期：2006-11-01 00:00:00

abstract：:The effects of crystal and beam tilt on high-resolution transmission electron microscope (HRTEM) images of planar coherent interfaces were investigated by multislice image simulations. It was found that a beam tilt of 0.5 Bragg angle (theta B) was sufficient to introduce detrimental artifacts into most images of inter...

journal_title：Microscopy research and technique

authors： Howe JM,Rozeveld SJ

更新日期：1992-11-01 00:00:00

abstract：:The construction of the liver parenchyma throughout fetal development depends on the elaboration of intercellular contacts between epithelial cells and between epithelial and mesenchymal cells. During this time, the spatial distribution of cytokeratins in hepatocytes shows a striking evolution as demonstrated by confo...

journal_title：Microscopy research and technique

authors： Vassy J,Irinopoulou T,Beil M,Rigaut JP

更新日期：1997-12-01 00:00:00

abstract：:We present de novo studies and review published efforts from our laboratory, spanning 12 years (from 1988 to 2000), where we have used ultrastructural approaches to study the functional anatomy of the microvasculature in man and animals in health and disease. These efforts have defined a new endothelial cell organelle...

journal_title：Microscopy research and technique

authors： Feng D,Nagy JA,Dvorak HF,Dvorak AM

更新日期：2002-06-01 00:00:00

abstract：:In spite of accumulating evidence for a modulation of sympathetic neurotransmission by endogenously produced nitric oxide (NO), it remains unclear in which parts of the vascular system and at what level this interaction takes place. The aim of the present study was to investigate the distribution of endothelial and ne...

journal_title：Microscopy research and technique

authors： Addicks K,Bloch W,Feelisch M

更新日期：1994-10-01 00:00:00

abstract：PURPOSE:To evaluate the influence of irrigation protocols and drying procedures on the bond strength of two methacrylate-based sealers to dentin and the associated failure pattern using scanning electron microscopy (SEM). MATERIALS AND METHODS:Fifty single-rooted human teeth were prepared with an irrigation protocol u...

journal_title：Microscopy research and technique

authors： Fuzinatto RN,Farina AP,Souza MA,Miyagaki DC,Randi Ferraz CC,Cecchin D

更新日期：2017-06-01 00:00:00

abstract：:To investigate intrinsic physicochemical properties and interactions of three different calcium hydroxide-based medications via means of different analytical methods. Two-commercial premixed medications: TempCanal(TCmx) and ProCalR(PCmx) and powder-form ProCal(PCpw) with glycerin were used. Vibrational modes were anal...

journal_title：Microscopy research and technique

authors： Uslu O,Dikmen G,Orhan EO

更新日期：2020-09-21 00:00:00

abstract：:The family Scrophulariaceae consists of taxonomically complex genera and species. The delimitation of the taxa within this family is always challenging. In this paper, we studied leaf epidermis anatomical characteristics and its taxonomic significance of four species belonging to four genera of the family Scrophularia...

journal_title：Microscopy research and technique

authors： Ullah F,Ayaz A,Saqib S,Parmar G,Bahadur S,Zaman W

更新日期：2020-09-29 00:00:00

abstract：:In animal oocytes, the centrosome exists as an acentriolar aggregate of centrosomal material that is regulated in a dynamic manner throughout the process of meiotic maturation. Recently, it has been demonstrated that in female meiotic systems spindle assembly is likely regulated by chromosomal and microtubule/microtub...

journal_title：Microscopy research and technique

authors： Carabatsos MJ,Combelles CM,Messinger SM,Albertini DF

更新日期：2000-06-01 00:00:00

abstract：:Voltage-gated sodium channels are largely localized to the nodes of Ranvier in myelinated axons, providing the physiological basis for saltatory conduction. Studies using antisodium channel antibodies have shown that along demyelinated axons sodium channels form new distributions. The nature of this changed distributi...

journal_title：Microscopy research and technique

authors： England JD,Levinson SR,Shrager P

更新日期：1996-08-01 00:00:00

abstract：:The purpose of this study was to evaluate mineral content of root canal dentin after treatment with different antibiotic pastes including the mixture of metronidazole, ciprofloxacin, doxycycline, cefaclor, amoxicillin, or minocycline. Fifty extracted maxillary canine teeth were randomly divided into five groups (n = 1...

journal_title：Microscopy research and technique

authors： Simsek H,Coruh M,Cakici F,Fundaoglu Kucukekenci F,Gurbuz T,Cakici EB

更新日期：2019-02-01 00:00:00

abstract：:We report on a novel laser source, emitting high energy (20 nanoJoule) femtosecond pulses, in a broad spectrum (250 nm). This source is easily tuned from 950 to 1200 nm, without any laser adjustment, and delivers sub-300 femtosecond pulses with a 10-nm spectral width. ...

journal_title：Microscopy research and technique

authors： Deguil N,Mottay E,Salin F,Legros P,Choquet D

更新日期：2004-01-01 00:00:00

abstract：:We present here the phasor approach to biosensor Förster resonance energy transfer (FRET) detection by fluorescence lifetime imaging microscopy (FLIM) and show that this method of data representation is robust towards biosensor design as well as the fluorescence artifacts inherent to the cellular environment. We demon...

journal_title：Microscopy research and technique

authors： Hinde E,Digman MA,Welch C,Hahn KM,Gratton E

更新日期：2012-03-01 00:00:00

abstract：:Number of molecules and Brightness (N&B) has been proposed for measuring the molecular brightness and number of fluorophores in time-sequence of images, in live cells. If the fluorescently tagged-proteins are mobile in the illumination volume, the stoichiometry of their oligomers can be derived from the increase of th...

journal_title：Microscopy research and technique

authors： Trullo A,Corti V,Arza E,Caiolfa VR,Zamai M

更新日期：2013-11-01 00:00:00

abstract：:High speed data registration is required for the study of fluorescence resonance energy transfer in real time as well as fast dynamic intra- and inter-cellular signaling events. Multispectral confocal spinning disk microscopy provides a high resolution method for performing such real time live cell imaging. However, o...

journal_title：Microscopy research and technique

authors： Perrine KA,Lamarche BL,Hopkins DF,Budge SE,Opresko LK,Wiley HS,Sowa MB

更新日期：2007-04-01 00:00:00

abstract：:This paper summarizes the essential features of the various facilities dedicated to in situ irradiation effects research around the world at the present time, mentions some essential techniques that are involved in this type of research, and describes very briefly some examples of studies employing these facilities an...

journal_title：Microscopy research and technique

authors： Allen CW,Ryan EA

更新日期：1998-08-15 00:00:00

abstract：:The increasing importance of in vitro models has presented new challenges in SEM processing techniques. The present study has evaluated the quality of preservation of cultured human lens epithelial cells processed by critical point, Peldri II, and tert-butyl alcohol drying. Specimens processed by critical point drying...

journal_title：Microscopy research and technique

authors： Cantu-Crouch D,Howe WE,McCartney MD

更新日期：1995-04-01 00:00:00

abstract：:Fluorescence correlation spectroscopy (FCS) has become an increasingly important measurement tool for biological and biomedical investigations, with the capability to assay molecular dynamics and interactions both in vitro and within living cells. Information recovery in FCS requires an accurate characterization and c...

journal_title：Microscopy research and technique

authors： Wu J,Berland K

更新日期：2007-08-01 00:00:00

abstract：:Choroid plexus (CP) is an important target organ for polypeptides. The fenestrated phenotype of choroidal endothelium facilitates the penetration of blood-borne polypeptides across the capillary walls. Thus, both circulating and cerebrospinal fluid (CSF)-borne polypeptides can reach their receptors on choroidal epithe...

journal_title：Microscopy research and technique

authors： Chodobski A,Szmydynger-Chodobska J

更新日期：2001-01-01 00:00:00

abstract：:TGF-beta1 is an important regulator of the normal and malignant prostate. In the non-malignant prostate, TGF-beta1 stimulates cell differentiation, inhibits epithelial cell proliferation, and induces epithelial cell death. TGF-beta1 is secreted into semen where it is an important immunosuppressive factor. Prostate can...

journal_title：Microscopy research and technique

authors： Wikström P,Damber J,Bergh A

更新日期：2001-02-15 00:00:00

abstract：:In this study, we aimed to increase the sensitivity of protein labeling using 1.4 nm gold nanoparticles and glutamate δ2 receptor (GluD2) from the postsynaptic membrane of the Purkinje cells. The very small marker size of the particles reduces the steric hindrance between antibodies leading to a higher labeling effici...

journal_title：Microscopy research and technique

authors： Loukanov AR,Gagov H

更新日期：2012-09-01 00:00:00

abstract：:The mechanical properties of healing ligaments and tendons are not comparable to those of normal tissue. To improve the quality of the ligament healing, therapeutic strategies include gene transfer or placement of mesenchymal stem cells at the healing site. Studies show that marker genes, growth factors, and antisense...

journal_title：Microscopy research and technique

authors： Hildebrand KA,Jia F,Woo SL

更新日期：2002-07-01 00:00:00

abstract：:Aluminum-lithium alloy is regarded as the most promising light material in the aircraft and aerospace industries. For the production of complex and high-precision parts, the hot forming with synchronous quenching (HFSQ) process has become an effective and attractive forming method. In order to achieve the performance ...

journal_title：Microscopy research and technique

authors： Zhang P,Chen MH,Chen W,Zhang SH,Xu Y

更新日期：2021-02-01 00:00:00

abstract：:The cyclic fluctuations in circulating levels of 17 beta-estradiol and progesterone that occur during the menstrual or estrous cycle are responsible for dramatic, cyclic changes in the epithelial lining and secretory status of the mammalian oviduct. The timely transition in the synthesis and release of oviduct protein...

journal_title：Microscopy research and technique

authors： Murray MK,DeSouza MM,Messinger SM

更新日期：1995-08-15 00:00:00

abstract：:This study represents the first attempt to describe the ultra-structural and histological features of different three age-stages (young, mature, and adult) of rock pigeon Columba livia dakhlae captured from Egypt. The elongated tongue with round lingual apex carried a lingual nail rostrally on lingual tip. The current...

journal_title：Microscopy research and technique

authors： Abumandour MMA,Kandyel RM

更新日期：2020-02-01 00:00:00

abstract：:This article deals with the modeling and simulation of the vibration behavior of piezoelectric micro-cantilever (MC) based on the Timoshenko theory and using multi-scale (MTS) method in the air environment. In this regard, the results are compared with the previous literature, such as the finite element method and the...

journal_title：Microscopy research and technique

authors： Korayem AH,Imani F,Korayem MH

更新日期：2019-10-01 00:00:00

abstract：:The human dentin-enamel junction (DEJ) is a natural junction that unites two dissimilar mineralized tissues in the human tooth: enamel and dentin. DEJ plays a critical role in maintaining structural and functional integrity of the tooth. However, its structure, chemical composition and function remain unclear and cont...

journal_title：Microscopy research and technique

authors： Wang R,Zhao D,Wang Y

更新日期：2020-11-19 00:00:00

abstract：:The energy resolution of an energy dispersive spectrometer (EDS) equipped with an ultrathin window (UTW) and mounted at a high take-off angle (72 degrees) on a transmission electron microscope has been studied under a variety of operating conditions. The spectrometer resolution is close to that specified by the manufa...

journal_title：Microscopy research and technique

authors： Blackford MG,Smith KL

更新日期：1992-07-01 00:00:00