Abstract:
:Altered cerebral gray matter volume (GMV) is commonly found in patients with chronic pain. Chronic pain is the prominent characteristic of knee osteoarthritis (KOA), yet little is known about its morphological changes in the brain. Here an MRI study was performed to examine the structural brain abnormalities in 30 KOA patients with knee pain and age-matched healthy subjects. We detected that the patients exhibited significant almost 2-fold age-related decreases of GMV compared to healthy controls. Moreover, KOA patients also had significant loss of regional GMV including in the bilateral orbital frontal cortex (OFC), the right lateral prefrontal cortex (lPFC), and precentral and postcentral cortices. In addition, a high proportion of KOA patients exerted abnormal scores of Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Scale (HAMA), Mini Mental State examination (MMSE), and Montreal Cognitive Assessment (MoCA) compare to controls. Our results imply that chronic pain conditions which preferentially involve PFC might consider as a "cognitive state." And emotion and cognitive function about chronic pain should be highly regarded.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Liao X,Mao C,Wang Y,Zhang Q,Cao D,Seminowicz DA,Zhang M,Yang Xdoi
10.1097/MD.0000000000010145subject
Has Abstractpub_date
2018-03-01 00:00:00pages
e0145issue
12eissn
0025-7974issn
1536-5964pii
00005792-201803230-00015journal_volume
97pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Repair of soft tissue defects on the dorsum of the hand with accompanying tendon defects is a challenging problem in clinical practice. PATIENT CONCERNS:Here, we describe the case of a 3-year-old boy with a 1-week old soft tissue injury with infection due to a soft tissue defect on the dorsum of his right ha...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021837
更新日期:2020-08-21 00:00:00
abstract::The aim of this paper was to evaluate the activity and tolerability of oral vinorelbine in patients with advanced castration resistant prostate cancer (CRPC) who progressed after a minimum of three lines including: abiraterone acetate, docetaxel, cabazitaxel, and enzalutamide.Treatment consisted of weekly oral vinorel...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016249
更新日期:2019-06-01 00:00:00
abstract::Impact of arterial stiffness on aortic morphology has not been well evaluated. We sought to investigate the association of brachial-ankle pulse wave velocity (baPWV) with aortic calcification and tortuosity.A total of 181 patients (65.4 ± 10.4 years, males 59.7%) who underwent computed tomographic angiography and baPW...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016802
更新日期:2019-08-01 00:00:00
abstract::Several studies have investigated the diagnostic accuracy of procalcitonin (PCT) levels in blood or cerebrospinal fluid (CSF) in bacterial meningitis (BM), but the results were heterogeneous. The aim of the present study was to ascertain the diagnostic accuracy of PCT as a marker for BM detection. A systematic search ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000003079
更新日期:2016-03-01 00:00:00
abstract:RATIONALE:Supernumerary teeth are those that teeth in excess number than the normal count. It is usually associated with genetic syndromes when present in more numbers. Several causal genes, such as APC, NHS, TRPS1, EVC and RUNX2, have been identified. However, etiology of supernumerary teeth remains largely unclear. ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000011328
更新日期:2018-08-01 00:00:00
abstract::Bisphenol A (BPA) is an environmental endocrine disruptor that has been associated with cardiovascular outcomes in previous observational studies. We aimed to examine the relationships of urinary BPA levels with hypertension and early macrovascular diseases.This is a cross-sectional study. From June through August 200...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001814
更新日期:2015-10-01 00:00:00
abstract::Data on the association of dietary patterns with non-alcoholic fatty liver disease (NAFLD) among adolescents are scarce. Hence, the purpose of this study was to ascertain the influence of dietary patterns and key foods on NAFLD among adolescents in Shandong, China. Data were extracted from Linyi Nutrition and Health s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010576
更新日期:2018-04-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000000510.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000484495.36196.d5
更新日期:2016-06-10 00:00:00
abstract:BACKGROUND:A growing number of studies have suggested that the Long intergenic noncoding RNA 00511 (LINC00511) is aberrantly expressed in multiple malignancies and is related to patient survival. Herein, we conducted a systematic review and meta-analysis to comprehensively evaluate the prognostic significance of LINC00...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000023054
更新日期:2020-11-06 00:00:00
abstract:BACKGROUND:Kangfuxin (KFX), a well-known Chinese patent medicine which extracted from Periplaneta americana, is widely used as an adjuvant in the treatment of peptic ulcers (PUs) with proton pump inhibitors (PPIs) such as rabeprazole, in China. However, no clear consensus has been reached on the efficacy for PU treatme...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000023103
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:Water immersion delivery is a non-pharmacological approach to ease labor pain. This paper aims to investigate the effect of water immersion delivery on increasing strength of pelvic floor muscle (PFM) and relieving pelvic floor disorders (PFDs) during postpartum period. METHODS:A total of 2749 vaginal-deliv...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008124
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:The role of real-time elastography (RTE)-targeted biopsy in the detection and diagnosis of prostate cancer (PCa) remains controversial. METHODS:We searched Medline, Embase, and Cochrane Library from inception to July 31, 2017 and used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool to ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000010220
更新日期:2018-03-01 00:00:00
abstract::Detailed characterizations of ocular biometrics and parameters of aqueous humor dynamics are lacking in primary angle closure suspect (PACS) patients. This study aims to characterize these parameters and compare them with age-matched healthy volunteers.Elderly healthy volunteers (60.6 ± 7.2 years of age, mean ± SD, n ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006096
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:Purpuric drug eruption (PDE) is an uncommon, clinically distinct side effect of epidermal growth factor receptor (EGFR) inhibitors. PATIENT CONCERNS:Unlike acneiform eruption, which arises from hair follicles mainly in the head and neck area, PDE starts from xerosis cutis, primarily in the lower extremiti...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018112
更新日期:2019-11-01 00:00:00
abstract::Assessment of sedentary behaviors in children and adolescents with type 1 diabetes (T1D), relative to the method of insulin therapy used, and in comparison to healthy controls.The study group consisted of 215 children with T1D, including 109 (50.7%) insulin pen and 106 (49.3%) insulqsain pump users. The control group ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015625
更新日期:2019-05-01 00:00:00
abstract::Although facial pain expressions are considered to be the most visible pain behaviors, it is known that the association between pain intensity and facial pain expression is weak for chronic pain. The authors hypothesized that the facial pain expressiveness was altered in chronic pain and investigated it with a mental ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007990
更新日期:2017-09-01 00:00:00
abstract::The role of 18F-fuorodexoyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) in the staging of Hodgkin lymphoma (HL) and aggressive B-cell non-Hodgkin lymphomas (NHL) has been demonstrated extensively. Nevertheless, the role of PET/CT in the diagnosis, staging, prognosis, and treatment evaluatio...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000000258
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Rotavirus infection is the main cause of severe dehydration enteritis in children under 5 years old. It gives rise to malnutrition and even death in children even though there were rotavirus vaccines. However, there is no effective anti-virus drugs for rotavirus, supporting treatments are used in the clinics...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000023376
更新日期:2020-12-04 00:00:00
abstract:OBJECTIVE:We conducted a Pooled analysis to investigate the efficacy and safety of ureteral stent removal using an extraction string. METHODS:A systematic review was performed by using the Preferred Reporting Items for Systematic Reviews and Pooled analyses. The sources including EMBASE, MEDLINE, and the Cochrane Cont...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000017169
更新日期:2019-09-01 00:00:00
abstract:RATIONALE:Bronchial foreign body aspiration is a critical condition that jeopardizes the respiratory function of children. Prompt diagnosis and removal of the foreign body can reduce occurrence of foreign body complications and mortality. Aspiration of spherical plastic beads is rare, and the bead is difficult to retri...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012147
更新日期:2018-09-01 00:00:00
abstract::Hepatocyte nuclear factor 1 beta (HNF1B) plays an important role in embryonic development, namely in the kidney, pancreas, liver, genital tract, and gut. Heterozygous germline mutations of HNF1B are associated with the renal cysts and diabetes syndrome (RCAD). Affected individuals may present a variety of renal develo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000469
更新日期:2015-02-01 00:00:00
abstract::To investigate the prevalence, awareness, treatment, and control of hypertension, and the associated risk factors among adults in Xi'an, China.From October to December 2013, participants in Xi'an, China were recruited for the study by using a multiple-stage sampling method. A self-developed questionnaire with an addit...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004709
更新日期:2016-08-01 00:00:00
abstract::Nucleobindin 2 (NUCB2) has been reported to play an important role in both tumorigenesis and cancer progression. This study aimed to examine the clinical significance of NUCB2 expression urothelial carcinoma of the bladder (UCB).The expression level of NUCB2 and its correlation with clinicopathological parameters was ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019597
更新日期:2020-03-01 00:00:00
abstract::School sandplay group therapy is a useful clinical treatment method for adolescents who cannot adapt to school due to various emotional and behavioral problems. In this study, we conducted 10 weeks of group therapy in 70 adolescents referred to as maladjustment behavior problem in the school. The purpose of this study...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023272
更新日期:2020-12-11 00:00:00
abstract:RATIONALE:Collecting duct carcinoma (CDC) is a rare type of nonclear renal cell carcinoma, often presenting at an advanced stage of the disease, and standard treatment guidelines have not been established. PATIENT CONCERNS:A 73-year-old man was admitted to our hospital with complaints of fever and lower right back pai...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013173
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:To investigate the efficacy and advantage of combining situ-morcellation with continuous-fill-mattress suture compared with conventional morcellation and suture in laparoscopic myomectomy. METHODS:One hundred sixteen patients who underwent laparoscopic myomectomy from March 2014 to October 2016. INTERVENTI...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007672
更新日期:2017-08-01 00:00:00
abstract::This meta-analysis mainly summarized the studies reporting an association between statin use and cancer-specific mortality and recurrence or progression of cancer patients.We systematically searched for studies about the statin used in cancer patients in electronic databases, including PubMed, Web of Science, Cochrane...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000019596
更新日期:2020-04-01 00:00:00
abstract::Genetic etiology hypothesis is widely accepted in the development of congenital scoliosis (CS). The delta-like 3 (DLL3) gene, a member of the Notch signaling pathway, was implicated to contribute to human CS. In this study, a case-control association study was conducted to determine the association of single nucleotid...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004347
更新日期:2016-07-01 00:00:00
abstract:RATIONALE:Sternoclavicular joint septic arthritis is an unusual disease in healthy adults, and Staphylococcus aureus is the most common causative pathogen. The current treatment of choice is surgery with sternoclavicular joint resection and pectoralis flap closure, especially when the disease is complicated by osteomye...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022938
更新日期:2020-10-30 00:00:00
abstract:OBJECTIVE:Postpartum depression (PPD) is an episode of major depressive disorder that affecting women of childbearing age. 5-HTTLPR is 1 of the most extensively investigated polymorphisms in PPD. However, the previous results were inconsistent and inclusive. Hence, we performed a meta-analysis to precisely evaluate the...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022319
更新日期:2020-09-25 00:00:00