Author Correction: Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing.

abstract：:Plants perceive and respond to volatile signals in their environment. Herbivore-infested plants release volatile organic compounds (VOCs) which can initiate systemic defense reactions within the plant and contribute to plant-plant communication. Here, for Ipomoea batatas (sweet potato) leaves we show that among variou...

journal_title：Scientific reports

authors： Meents AK,Chen SP,Reichelt M,Lu HH,Bartram S,Yeh KW,Mithöfer A

更新日期：2019-11-22 00:00:00

abstract：:The salmon louse is an ectoparasitic copepod of salmonids in the marine environment, and represents a global challenge to salmon aquaculture. A major issue is the reliance of the industry on a limited number of chemicals to delouse salmonids on farms, and the high levels of resistance that lice have developed to all o...

journal_title：Scientific reports

authors： Kaur K,Besnier F,Glover KA,Nilsen F,Aspehaug VT,Fjørtoft HB,Horsberg TE

更新日期：2017-09-27 00:00:00

abstract：:Polyphenol oxidases (PPOs) are ubiquitously distributed among plants, bacteria, fungi and animals. They catalyze the hydroxylation of monophenols (monophenolase activity) and the oxidation of o-diphenols (diphenolase activity) to o-quinones. PPOs are commonly present as an isoenzyme family. In walnut (Juglans regia), ...

journal_title：Scientific reports

authors： Panis F,Rompel A

更新日期：2020-07-02 00:00:00

abstract：:Amplification and sequencing of 16S amplicons are widely used for profiling the structure of oral microbiota. However, it remains not clear whether and to what degree DNA extraction and targeted 16S rRNA hypervariable regions influence the analysis. Based on a mock community consisting of five oral bacterial species i...

journal_title：Scientific reports

authors： Teng F,Darveekaran Nair SS,Zhu P,Li S,Huang S,Li X,Xu J,Yang F

更新日期：2018-11-05 00:00:00

abstract：:Acid-base homeostasis is critical for normal growth, development, and hearing function. The sodium-hydrogen exchanger 6 (NHE6), a protein mainly expressed in early and recycling endosomes, plays an important role in regulating organellar pH. Mutations in NHE6 cause complex, slowly progressive neurodegeneration. Little...

journal_title：Scientific reports

authors： Kucharava K,Brand Y,Albano G,Sekulic-Jablanovic M,Glutz A,Xian X,Herz J,Bodmer D,Fuster DG,Petkovic V

更新日期：2020-02-27 00:00:00

abstract：:Staphylococcus aureus strains carrying enterotoxin A gene (sea) causes food poisoning and cannot be distinguished from non-pathogenic strains by the culture method. Here, we developed a rapid, specific and sensitive visual detection of sea using loop-mediated isothermal amplification (LAMP) combined with nanogold prob...

journal_title：Scientific reports

authors： Srimongkol G,Ditmangklo B,Choopara I,Thaniyavarn J,Dean D,Kokpol S,Vilaivan T,Somboonna N

更新日期：2020-05-08 00:00:00

abstract：:Atropa acuminata Royle Ex Lindl (Atropa acuminata) under tremendous threat of extinction in its natural habitat. However, the antimicrobial, antileishmanial and anticancer effects of the plant's extracts have not been reported yet. In the current study, an attempt has been made to evaluate the pharmacological potentia...

journal_title：Scientific reports

authors： Rahman K,Khan SU,Fahad S,Shinwari ZK,Khan D,Kamal S,Ullah I,Anjum SI,Man S,Khan AJ,Khan WU,Khan MHU,Jan M,Adnan M,Noor M

更新日期：2018-07-23 00:00:00

abstract：:The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. This has important implic...

journal_title：Scientific reports

authors： Zhang H,Lim HS,Knapp B,Deane CM,Aleksic M,Dushek O,van der Merwe PA

更新日期：2016-10-13 00:00:00

abstract：:Wolfram syndrome (WS) is a rare neurodegenerative disorder that is mainly characterized by diabetes mellitus, optic nerve atrophy, deafness, and progressive brainstem degeneration. Treatment with GLP-1 receptor agonists has shown a promising anti-diabetic effect in WS treatment in both animal models and in human patie...

journal_title：Scientific reports

authors： Seppa K,Toots M,Reimets R,Jagomäe T,Koppel T,Pallase M,Hasselholt S,Krogsbæk Mikkelsen M,Randel Nyengaard J,Vasar E,Terasmaa A,Plaas M

更新日期：2019-10-31 00:00:00

abstract：:Ca(x)Zn(1-x)O alloys are potential candidates to achieve wide band-gap, which might significantly promote the band gap engineering and heterojunction design. We performed a crystal structure search for CaO-ZnO system under pressure, using an ab initio evolutionary algorithm implemented in the USPEX code. Four stable o...

journal_title：Scientific reports

authors： Sha X,Tian F,Li D,Duan D,Chu B,Liu Y,Liu B,Cui T

更新日期：2015-07-17 00:00:00

abstract：:The way teeth grow is recorded in dental enamel as incremental marks. Detailed analysis of tooth growth is known to provide valuable insights into the growth and the pace of life of vertebrates. Here, we study the growth pattern of the first lower molar in several extant and extinct species of Equus and explore its re...

journal_title：Scientific reports

authors： Nacarino-Meneses C,Jordana X,Orlandi-Oliveras G,Köhler M

更新日期：2017-11-21 00:00:00

abstract：:Recent evidence suggests that some seizures are preceded by preictal changes that start from minutes to hours before an ictal event. Nevertheless an adequate statistical evaluation in a large database of continuous multiday recordings is still missing. Here, we investigated the existence of preictal changes in long-te...

journal_title：Scientific reports

authors： Alvarado-Rojas C,Valderrama M,Fouad-Ahmed A,Feldwisch-Drentrup H,Ihle M,Teixeira CA,Sales F,Schulze-Bonhage A,Adam C,Dourado A,Charpier S,Navarro V,Le Van Quyen M

更新日期：2014-04-01 00:00:00

abstract：:In this paper, we propose a real time, ultrahigh accuracy and full-field-of-view (RUF) algorithm for full field of view (FOV) imaging system. The proposed algorithm combines rough matching and precise matching method to stitch multiple images with the whole FOV in short time and high imaging quality. In order to verif...

journal_title：Scientific reports

authors： Liu SB,Wang JH,Yuan RY,Zhao WX,Li L,Wang QH

更新日期：2020-07-24 00:00:00

abstract：:Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC II transactivation...

journal_title：Scientific reports

authors： Fan Z,Li J,Li P,Ye Q,Xu H,Wu X,Xu Y

更新日期：2017-01-17 00:00:00

abstract：:Hepatocellular carcinoma is the third leading cause of cancer-related deaths worldwide. Many patients are not eligible for curative therapies, such as surgical resection of the tumor or a liver transplant. Transarterial embolization is one therapy clinically used in these cases; however, this requires a long procedure...

journal_title：Scientific reports

authors： Harmon JS,Kabinejadian F,Seda R,Fabiilli ML,Kuruvilla S,Kuo CC,Greve JM,Fowlkes JB,Bull JL

更新日期：2019-07-30 00:00:00

abstract：:AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex ligand, C8, to HeLa can...

journal_title：Scientific reports

authors： Carvalho J,Paiva A,Cabral Campello MP,Paulo A,Mergny JL,Salgado GF,Queiroz JA,Cruz C

更新日期：2019-05-28 00:00:00

abstract：:Craniosynostosis must often be corrected using surgery, by which the affected bone tissue is remodeled. Nowadays, surgical reconstruction relies mostly on the subjective judgement of the surgeon to best restore normal skull shape, since remodeled bone is manually placed and fixed. Slight variations can compromise the ...

journal_title：Scientific reports

authors： García-Mato D,Ochandiano S,García-Sevilla M,Navarro-Cuéllar C,Darriba-Allés JV,García-Leal R,Calvo-Haro JA,Pérez-Mañanes R,Salmerón JI,Pascau J

更新日期：2019-11-27 00:00:00

abstract：:Phagocytosis is a process in which target cells or particles are engulfed and taken up by other cells, typically professional phagocytes; this process is crucial in many physiological processes and disease states. The detection of targets for phagocytosis is directed by a complex repertoire of cell surface receptors. ...

journal_title：Scientific reports

authors： Schulz D,Severin Y,Zanotelli VRT,Bodenmiller B

更新日期：2019-02-13 00:00:00

abstract：:Qinghai Lake is a major migrating bird breeding site that has experienced several recent highly pathogenic avian influenza virus (HPAIV) epizootics. From 2006 to 2009 we studied Qinghai's wild birds and pikas for evidence of AIV infections. We sampled 941 healthy wild animals and isolated seventeen H7N2 viruses (eight...

journal_title：Scientific reports

authors： Su S,Xing G,Wang J,Li Z,Gu J,Yan L,Lei J,Ji S,Hu B,Gray GC,Yan Y,Zhou J

更新日期：2016-08-24 00:00:00

abstract：:We have studied both experimentally and theoretically the reprogrammable spin wave band structure in Permalloy(10 nm)/Cu(5 nm)/Permalloy(30 nm) nanowire arrays of width w = 280 nm and inter-wire separation in the range from 80 to 280 nm. We found that, depending on the inter-wire separation, the anti-parallel configur...

journal_title：Scientific reports

authors： Gubbiotti G,Zhou X,Haghshenasfard Z,Cottam MG,Adeyeye AO,Kostylev M

更新日期：2019-03-15 00:00:00

abstract：:We consider the electromagnetic response of a topological Weyl semimetal (TWS) with a pair of Weyl nodes in the bulk and corresponding Fermi arcs in the surface Brillouin zone. We compute the frequency-dependent complex conductivities σαβ(ω) and also take into account the modification of Maxwell equations by the topol...

journal_title：Scientific reports

authors： Kargarian M,Randeria M,Trivedi N

更新日期：2015-08-03 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a common liver disease. Previous studies on the association between Helicobacter pylori (HP) infection and NAFLD are inconsistent. Our study was aimed to find out the relationship between HP infection and NAFLD. We performed a large cross-sectional study in northern Chinese...

journal_title：Scientific reports

authors： Jiang T,Chen X,Xia C,Liu H,Yan H,Wang G,Wu Z

更新日期：2019-03-19 00:00:00

abstract：:Climate change vulnerability assessment (CCVA) has become a mainstay conservation decision support tool. CCVAs are recommended to incorporate three elements of vulnerability - exposure, sensitivity and adaptive capacity - yet, lack of data frequently leads to the latter being excluded. Further, weighted or unweighted ...

journal_title：Scientific reports

authors： Ofori BY,Stow AJ,Baumgartner JB,Beaumont LJ

更新日期：2017-10-11 00:00:00

abstract：:Biomaterial injection is a novel therapy to treat ischemic heart failure (HF) that has shown to reduce remodeling and restore cardiac function in recent preclinical studies. While the effect of biomaterial injection in reducing mechanical wall stress has been recently demonstrated, the influence of biomaterials on the...

journal_title：Scientific reports

authors： Ramírez WA,Gizzi A,Sack KL,Guccione JM,Hurtado DE

更新日期：2020-07-31 00:00:00

abstract：:The ability to arrange cells and/or microparticles into the desired pattern is critical in biological, chemical, and metamaterial studies and other applications. Researchers have developed a variety of patterning techniques, which either have a limited capacity to simultaneously trap massive particles or lack the spat...

journal_title：Scientific reports

authors： Zhang Y,Lei J,Zhang Y,Liu Z,Zhang J,Yang X,Yang J,Yuan L

更新日期：2017-10-30 00:00:00

abstract：:Because of the small particle number of intracellular species participating in genetic circuits, stochastic fluctuations are inevitable. This intracellular noise is detrimental to precise regulation. To maintain the proper function of a cell, some natural motifs attenuate the noise at the protein level. In many biolog...

journal_title：Scientific reports

authors： Liu FY,Lo SC,Shu CC

更新日期：2019-03-04 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xu X,Zhao J,Wang M,Wang L,Yang J

更新日期：2020-02-06 00:00:00

abstract：:Cholecystokinin (CCK) and leptin are satiety-controlling peptides, yet their interactive roles remain unclear. Here, we addressed this issue using in vitro and in vivo models. In rat C6 glioma cells, leptin pre-treatment enhanced Ca2+ mobilization by a CCK agonist (CCK-8s). This leptin action was reduced by Janus kina...

journal_title：Scientific reports

authors： Koizumi H,Mohammad S,Ozaki T,Muto K,Matsuba N,Kim J,Pan W,Morioka E,Mochizuki T,Ikeda M

更新日期：2020-07-20 00:00:00

abstract：:The eastern North American migratory population of monarch butterflies (Danaus plexippus) is in serious decline. Habitat restoration, including adding millions of host plants to compensate for loss of milkweed in US cropland, is a key part of the international conservation strategy to return this iconic butterfly to s...

journal_title：Scientific reports

authors： Baker AM,Potter DA

更新日期：2018-08-14 00:00:00

abstract：:Individuals infected with hepatitis C virus (HCV) are at high risk of developing progressive liver disease, including cirrhosis and hepatocellular carcinoma (HCC). How HCV infection causes liver destruction has been of significant interest for many years, and apoptosis has been proposed as one operative mechanism. In ...

journal_title：Scientific reports

authors： Kofahi HM,Taylor NG,Hirasawa K,Grant MD,Russell RS

更新日期：2016-12-15 00:00:00