Treatment of acute exacerbations of interstitial lung disease.

abstract：:Asthma is perceived as a heterogeneous disease with several clinical phenotypes and triggering factors. In general, cytokines from T-helper 2 cells are believed to be critical contributors of asthma. In recent years, IL-17, another T-helper lymphocyte-associated cytokine, has been put forward as another potentially im...

journal_title：Expert review of respiratory medicine

authors： Silverpil E,Lindén A

更新日期：2012-04-01 00:00:00

abstract：:Inhaled antibiotic therapy, targeting Pseudomonas aeruginosa, is a fundamental component of cystic fibrosis (CF) management. Tobramycin inhalation solution (TIS) was approved in the United States (US) in 1998. Subsequent research efforts focused on developing products with a reduced treatment time burden. Aztreonam fo...

journal_title：Expert review of respiratory medicine

authors： Fiel SB

更新日期：2014-06-01 00:00:00

abstract：:Chronic obstructive pulmonary disease is an inflammatory disorder characterized by airflow limitation. Its cardinal symptom is dyspnea, which develops gradually with even low levels of exercise. Bronchodilators (BDs) are the most effective drugs for relieving dyspnea. Two main types of BD are currently available, β-mi...

journal_title：Expert review of respiratory medicine

authors： Baloira A

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:The treatment of infection with Mycobacterium tuberculosis in young children is supported by universal policy based on strong rationale and evidence of effectiveness, but has rarely been implemented in tuberculosis endemic countries. Areas covered: This review highlights a number of important recent develo...

journal_title：Expert review of respiratory medicine

authors： Graham SM

更新日期：2017-01-01 00:00:00

abstract：:The hallmarks of allergic bronchial asthma arise from chronic airway inflammation. Thus, elucidating the mechanisms regulating the maintenance of this chronic inflammatory response is key to understanding asthma pathogenesis. To date, it is not clear whether a predominance of proinflammatory factors or a reduced capac...

journal_title：Expert review of respiratory medicine

authors： Lunding L,Schröder A,Wegmann M

更新日期：2015-01-01 00:00:00

abstract：:Premature infants are at substantial risk for a spectrum of morbidities that are gestational age dependent. Respiratory syncytial virus (RSV) infection is most common in the first two years of life with the highest burden in children aged <6 months. Preterm infants ≤35 weeks' gestation are handicapped by incomplete im...

journal_title：Expert review of respiratory medicine

authors： Abraha HY,Lanctôt KL,Paes B

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:The treatment of lung cancer has radically changed over the last few years. The discovery of druggable oncogenic alterations and the introduction of immunotherapy have provided lung cancer patients with the possibility of more efficient and less toxic therapeutic alternatives than chemotherapy. In the case...

journal_title：Expert review of respiratory medicine

authors： Lazzari C,Karachaliou N,Gregorc V,Bulotta A,Gonzalez-Cao M,Verlicchi A,Altavilla G,Rosell R,Santarpia M

更新日期：2017-06-01 00:00:00

abstract：:With advances in CT technology and the popularity of low-dose CT as a device for lung cancer screening, the detection rate of sub-solid pulmonary nodules as well as solid nodules has been increased. Distinguishing solid from sub-solid features is an essential step in the CT evaluation of solitary pulmonary nodules (SP...

journal_title：Expert review of respiratory medicine

authors： Cha MJ,Lee KS,Kim HS,Lee SW,Jeong CJ,Kim EY,Lee HY

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Approximately 14% of UK hospital in-patients receive supplemental oxygen therapy, only 57% have valid prescriptions. Oxygen must be optimally prescribed to ensure maximal therapeutic response whilst minimizing adverse outcomes (including fatality). This study investigates prescription compliance. METHODS:Al...

journal_title：Expert review of respiratory medicine

authors： Barrett R,Catangui E,Scott R

更新日期：2020-10-14 00:00:00

abstract：:Endobronchial ultrasound (EBUS) is an evolving diagnostic tool in respiratory medicine that allows the bronchoscopist to see beyond the airway. The radial probe EBUS was first introduced to evaluate the central airway structure. With advances in technology, the small radial probes can now visualize and assist transbro...

journal_title：Expert review of respiratory medicine

authors： Yasufuku K

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:Cardiorespiratory physiotherapy is an evidence-based practice that has evolved alongside changes in medical and surgical management, analgesia, the ageing society and increasing comorbidities of our patient populations. Continued research provides the profession with the ability to adapt to meet the changi...

journal_title：Expert review of respiratory medicine

authors： Denehy L,Granger CL,El-Ansary D,Parry SM

更新日期：2018-03-01 00:00:00

abstract：:Dendritic cells (DCs) are the most potent antigen-presenting cells in the human lung and are now recognized as crucial initiators of immune responses in general. They are arranged as sentinels in a dense surveillance network inside and below the epithelium of the airways and alveoli, where they are ideally situated to...

journal_title：Expert review of respiratory medicine

authors： Blank F,von Garnier C,Obregon C,Rothen-Rutishauser B,Gehr P,Nicod L

更新日期：2008-04-01 00:00:00

abstract：:Introduction: There is an unmet clinical need for improved diagnostic tests for active tuberculosis (TB) to provide high sensitivity for all cases, accelerate time to diagnosis and ensure timely and appropriate treatment. Whilst the measurement of M.tb-specific immune responses is widely used for detecting infection i...

journal_title：Expert review of respiratory medicine

authors： Halliday A,Masonou T,Tolosa-Wright M,Mandagere V,Lalvani A

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:The Global Initiative for Asthma (GINA) annual report summarizes the latest evidence for asthma management. GINA recommends stepwise pharmacological treatment, advocating inhaled corticosteroids (ICS) plus rapid, long-acting β2-agonists (LABA) delivered in a single inhaler for maintenance and relief at Ste...

journal_title：Expert review of respiratory medicine

authors： Lin J,Zhou X,Wang C,Liu C,Cai S,Huang M

更新日期：2018-03-01 00:00:00

abstract：:Background: Few studies have provided real-world evidence of mepolizumab efficacy and safety. We aimed to evaluate mepolizumab for severe eosinophilic asthma in daily clinical practice.Research design and methods: Patients included in the RINOVA (Interdisciplinary Network for the management of severe asthma in Veneto ...

journal_title：Expert review of respiratory medicine

authors： Caminati M,Cegolon L,Vianello A,Chieco Bianchi F,Festi G,Marchi MR,Micheletto C,Mazza F,Tognella S,Senna G

更新日期：2019-12-01 00:00:00

abstract：:Patients suffering from COPD not controlled by a single bronchodilator should be given two bronchodilators with different mechanisms of action. Addition of a LABA to a LAMA induces a larger bronchodilation than that obtained with the LAMA as monotherapy and also improves many patient-reported outcomes. Since the clini...

journal_title：Expert review of respiratory medicine

authors： Calzetta L,Ciaprini C,Puxeddu E,Cazzola M

更新日期：2016-04-01 00:00:00

abstract：:Budesonide/formoterol is a combination of an inhaled corticosteroid plus a long-acting beta(2)-agonist available as a dry-powder inhaler for the indication of asthma and chronic obstructive pulmonary disease in various countries outside of the USA and as a pressurized metered-dose inhaler in the USA for the indication...

journal_title：Expert review of respiratory medicine

authors： Lee C,Corren J

更新日期：2008-10-01 00:00:00

abstract：:Although wheezing illness is at its most prevalent in infancy and early childhood, its self-limiting nature in the majority poses considerable challenges in offering a long-term prognosis and in initiating long-term prophylaxis. Many of the established treatments in adults have not been adequately assessed in children...

journal_title：Expert review of respiratory medicine

authors： Helms PJ

更新日期：2009-04-01 00:00:00

abstract：:Introduction: Knowledge of the pathophysiology of cough has continued to advance over recent decades. Establishing anatomic-diagnostic protocols, based on the anatomy and distribution of vagus nerve pathways regulating the cough reflex, was the first breakthrough in modern clinical medicine for chronic cough. The unme...

journal_title：Expert review of respiratory medicine

authors： Song WJ,Chung KF

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:In sarcoidosis, muscle involvement is common, but mostly asymptomatic. Currently, little is known about respiratory muscle and diaphragm involvement and function in patients with sarcoidosis. Reduced inspiratory muscle strength and/or a reduced diaphragm function may contribute to exertional dyspnea, fatig...

journal_title：Expert review of respiratory medicine

authors： Schreiber T,Windisch W

更新日期：2018-07-01 00:00:00

abstract：:Techniques to promote clearance of sputum from the airways (airway clearance techniques; ACTs) have existed in clinical practice for more than a century. This review examines current evidence and clinical recommendations regarding ACTs for individuals with chronic obstructive pulmonary disease. Comparisons between thi...

journal_title：Expert review of respiratory medicine

authors： Osadnik CR,McDonald CF,Holland AE

更新日期：2013-12-01 00:00:00

abstract：:Sarcoidosis is a multisystem disease for which diagnosis relies on the integration of clinical, radiologic, laboratory, and pathologic information. Assessment of clinical features is an important part of the disease evaluation. Computer Tomography provides information not available on routine chest roentgenogram which...

journal_title：Expert review of respiratory medicine

authors： Zhou Y,Lower EE,Li H,Baughman RP

更新日期：2016-01-01 00:00:00

abstract：:Chronic respiratory disease is an increasingly prevalent cause of life-limiting illness. Care for patients with terminal respiratory diseases has historically focused on disease-modifying therapies, many of which have little impact on life expectancy. This exclusive focus can detract from attention to patient-physicia...

journal_title：Expert review of respiratory medicine

authors： Isaac M,Curtis JR

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) patients experience the morning as the worst period of the day. Nevertheless, morning symptoms are not mentioned in COPD guidelines. Areas covered: Different topics on morning symptoms are covered in this review to underline their importance: occurrence, tools f...

journal_title：Expert review of respiratory medicine

authors： van Buul AR,Kasteleyn MJ,Chavannes NH,Taube C

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The aim of this pilot study was to determine the combined effect of vitamin D and omega-3 polyunsaturated fatty acid (PUFA) supplementation on airway function and inflammation in recreational athletes with exercise-induced bronchoconstriction (EIB). METHODS:Ten recreational athletes with EIB participated in ...

journal_title：Expert review of respiratory medicine

authors： Price OJ,Hull JH,Howatson G,Robson-Ansley P,Ansley L

更新日期：2015-06-01 00:00:00

abstract：:Introduction: Muscle impairments are prevalent in COPD and have adverse clinical implications in terms of physical performance capacity, disease burden, quality of life and even mortality. During acute exacerbations of COPD (AECOPDs) the respiratory symptoms worsen and this might also apply to the muscle impairments. ...

journal_title：Expert review of respiratory medicine

authors： Gosker HR,Langen RC,Simons SO

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Cystic Fibrosis is among the first diseases to have general population genetic screening tests and one of the most common indications of prenatal and preimplantation genetic diagnosis for single gene disorders. During the past twenty years, thanks to the evolution of diagnostic techniques, our knowledge of...

journal_title：Expert review of respiratory medicine

authors： Bergougnoux A,Taulan-Cadars M,Claustres M,Raynal C

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Pleural disease encompasses a large range of conditions, is a common presentation to the acute medical take and often requires comprehensive investigation and treatment. Ultrasound is well recognised as a useful investigative tool in pleural disease especially in the field of pleural effusion, pleural thic...

journal_title：Expert review of respiratory medicine

authors： Mercer RM,Psallidas I,Rahman NM

更新日期：2017-04-01 00:00:00

abstract：:Although mechanical ventilation (MV) is a life-saving intervention for patients with acute respiratory distress syndrome (ARDS), it can aggravate or cause lung injury, known as ventilator-induced lung injury (VILI). The biophysical characteristics of heterogeneously injured ARDS lungs increase the parenchymal stress a...

journal_title：Expert review of respiratory medicine

authors： Plataki M,Hubmayr RD

更新日期：2010-06-01 00:00:00

abstract：:Owing to the prevalence, the considerable risk of accidents and cardiovascular consequences, optimal treatment of obstructive sleep apnea syndrome is of crucial importance. However, many patients look for alternative conservative or surgical therapies to continuous positive airway pressure to avoid discomfort and loca...

journal_title：Expert review of respiratory medicine

authors： Randerath WJ

更新日期：2009-06-01 00:00:00