Abstract:
:Pancreatic cancer (PC) has a very low average survival, but its prognosis is further reduced in the case of metastatic spread. Medical therapy in these cases is the only applicable methodology in the international guidelines. During anticancer treatments, common side effects are nausea, vomiting, arthralgia, neuropathy, and alopecia as well as a myelosuppressive effect. The toxicity of various drugs not only affects the quality of life of the patient, but often its severity requires a reduction in if not the termination of drug administration. Scientific studies have shown that a combined use of chemotherapy and certain natural substances, in the form of standardized extracts, can lead to an enhancement of the action of the chemotherapy. Here, we describe 2 cases of metastatic PC. The first case concerns the integrated treatment of a patient with cancer of the pancreas tail with metastatic involvement ab initio of peripancreatic lymph nodes and liver parenchyma, with numerous secondary lesions greater than 9.5 cm. The second case concerns the integrated treatment of a patient with cancer of the pancreatic body with metastatic involvement of the liver parenchyma, with a small secondary lesion. In both cases, an integrated cancer treatment approach, combining chemotherapy with natural remedies, extracts, and hyperthermia, induced a notable remission of primary and metastatic lesions.
journal_name
Integr Cancer Therjournal_title
Integrative cancer therapiesauthors
Bonucci M,Pastore C,Ferrera V,Fiorentini C,Fabbri Adoi
10.1177/1534735418755479subject
Has Abstractpub_date
2018-09-01 00:00:00pages
994-999issue
3eissn
1534-7354issn
1552-695Xjournal_volume
17pub_type
杂志文章abstract::Purpose Fatigue is an important problem in children receiving intensive chemotherapy and hematopoietic stem cell transplantation (HSCT). Exercise may be an effective intervention for fatigue. Individualized yoga represents an ideal intervention because it can be tailored according to an individual child's needs. Littl...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735416630806
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:Essential thrombocythemia, polycythemia vera, and myelofibrosis are rare chronic hematological malignancies known as myeloproliferative neoplasms (MPNs) and are characterized by deregulated myeloid lineage cell production, splenomegaly, and heterogeneous symptom profiles. MPN patients suffer from a significant ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735416661417
更新日期:2017-12-01 00:00:00
abstract:UNLABELLED:Objective Acquired chemoresistance is a major obstacle in the clinical management of ovarian cancer. Therefore, searching for alternative therapeutic modalities is urgently needed. Bitter melon (Momordica charantia) is a traditional dietary fruit, but its extract also shows potential medicinal values in huma...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735415611747
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:While many cancer patients derive strength from spiritual or religious faith, concern often remains regarding how different patient subgroups and other community members might react to faith-based services when sponsored by a secular health care organization. METHODS:"A Sacred Gathering for Those Touched by...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735405278640
更新日期:2005-09-01 00:00:00
abstract::Acute doxorubicin (DOX) cardiotoxicity can be attenuated by exercise preconditioning, but little is known of whether this cardioprotection continues beyond 10 days post-DOX administration. The purpose of this study was to determine the effects of exercise preconditioning on early chronic DOX-induced cardiotoxicity. Ma...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735410392577
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Although the importance of spiritual issues to people with cancer is by now widely acknowledged, there has been almost no research on the value of interventions specifically designed to enhance the spiritual experience of these patients. The present report describes an exploratory study on the effects of a brie...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735405275648
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:High-grade gliomas are the most common and invasive malignant brain tumors in adults, and they are almost universally fatal because of drug resistance and recurrence. In spite of the progress in adjuvant therapy (like temozolomide) and irradiation after surgery, no effective salvage therapy is currently avai...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735414549623
更新日期:2014-11-01 00:00:00
abstract:AIM:To introduce the application of wheel balance cancer therapy (WBCT) in cancer treatment through an intensive study of a representative patient. METHOD:A 59-year-old, female patient who was a secondhand smoker and who carried no significant medical and family history was diagnosed with T1N0M1 (stage 4) lung adenoca...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735410371479
更新日期:2010-06-01 00:00:00
abstract::Extracts of milk thistle have been recognized for centuries as "liver tonics" and are well-known to prevent or reverse hepatotoxicity of reactive drug metabolites or naturally occurring toxins. Milk thistle extracts are now under intense study in the experimental therapeutics of cancer for chemoprevention, treatment, ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735407301825
更新日期:2007-06-01 00:00:00
abstract::Antineoplastic agents induce oxidative stress in biological systems. During cancer chemotherapy, oxidative stress-induced lipid peroxidation generates numerous electrophilic aldehydes that can attack many cellular targets. These products of oxidative stress can slow cell cycle progression of cancer cells and cause cel...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735404270335
更新日期:2004-12-01 00:00:00
abstract::Nausea and vomiting are among the most common and distressing side effects of chemotherapy. Additional antiemetic drugs are urgently needed to effectively manage and ameliorate chemotherapy-induced nausea and vomiting (CINV). The efficacy of ginger as an antiemetic modality for ameliorating CINV has not been establish...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,随机对照试验
doi:10.1177/1534735417753541
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Melatonin (MLT) is known to possess potent antioxidant, antiproliferative, immune-modulating, and hormone-modulating properties. Clinical evidence suggests that MLT may have a possible role in the treatment of cancer. The authors systematically reviewed the effects of MLT in conjunction with chemotherapy, ra...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析,评审
doi:10.1177/1534735411425484
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Complementary and alternative medicine (CAM) is becoming more common in medical practice, but little is known about the concurrent use of CAM and conventional treatment. Therefore, the aim was to investigate the types of CAM used and their prevalence in a regional patient cohort with breast cancer (BC). MET...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420983910
更新日期:2020-01-01 00:00:00
abstract::Different vitamins and other micronutrients in vegetables, fruits, and other natural plant products may prevent cancer development (carcinogenesis) by interfering with detrimental actions of mutagens, carcinogens, and tumor promoters. The goal of current studies in cancer prevention is to determine the mechanisms of s...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735403002002005
更新日期:2003-06-01 00:00:00
abstract:PURPOSE:Many botanical immunomodulators are used as adjuvants along with cancer chemotherapy. However, information on the impact of concurrent administration of such botanicals on pharmacokinetics of chemotherapy agents is inadequate. This study investigates inhibitory activities of 3 popular botanical adjuvants: ASPAR...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735413503551
更新日期:2014-03-01 00:00:00
abstract::The aim of this study was to investigate the anticancer effect of a combination of D-fraction polysaccharide from Grifola frondosa (DFP) and vitamin C (VC) on hepatocellular carcinoma in vitro. DFP is a bioactive extract from the maitake mushroom. Anticancer activity was demonstrated using various concentrations of DF...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735416644674
更新日期:2017-06-01 00:00:00
abstract::Chronic inflammation may be a causative factor in breast cancer. One possible underlying mechanism is the generation of oxidative stress, which may favor tumorigenic processes. Antioxidant consumption may, therefore, help reduce tissue inflammation levels. However, few studies have explored this relation in breast tis...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735416676584
更新日期:2017-12-01 00:00:00
abstract::The large majority of clinical prostate cancers remain dependent on androgen receptor (AR) activity for proliferation even as they lose their responsiveness to androgen deprivation or antagonism. AR activity can be maintained in these circumstances by increased AR synthesis--often reflecting increased NF-κB activation...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735414534728
更新日期:2014-09-01 00:00:00
abstract::The circadian production of melatonin by the pineal gland during the night provides an inhibitory signal to tissue-isolated steroid receptor SR+ and - MCF-7 human breast cancer xenografts in female nude rats. A pivotal mechanism for melatonin's anticancer effects in vivo involves a melatonin receptor-mediated inhibiti...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735409352320
更新日期:2009-12-01 00:00:00
abstract::Purpose: This article discusses the results of an evaluation of the one-year implementation period of an integrative care program at a pediatric oncology ward, which consists of integrative care treatments offered three times a week to the patients. The guiding questions are how the model was implemented, which factor...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420928393
更新日期:2020-01-01 00:00:00
abstract::Malignant gliomas are the most common brain tumors with high rates of recurrence and mortality. Novel approaches are in research, and immunotherapy emerges as a promising strategy. Recently, scientific attention has been focused on Ganoderma lucidum polysaccharides (GL-PS), one of the critical bioactive components of ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418762537
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Chemoradiotherapy-associated mucositis can manifest as pain, inflammation, dysphagia, diarrhea, weight loss, rectal bleeding, and infection. Mucositis is a major dose-limiting side effect of chemotherapy, affecting nutritional intake and oral and intestinal function. Despite several interventions being avail...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418794885
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Physical activity (PA) is important in lung cancer. OBJECTIVES:To investigate PA levels and health-related quality of life (HRQoL) of patients with lung cancer in China and compare this to a similar cohort in Australia. METHODS:Prospective cohort study. 71 patients from China (group CH) and 90 patients f...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735417699513
更新日期:2018-06-01 00:00:00
abstract::There are increasing data showing that sonodynamic therapy (SDT), which refers to a synergistic effect of drugs and ultrasound, is a promising new modality for cancer treatment. However, few clinical data on SDT have been published. One reason is the lack of suitable drugs for clinical SDT use. Recently a new sonosens...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735408319065
更新日期:2008-06-01 00:00:00
abstract::Oncology is currently a sector of medical science with accelerated progress due to rapid technological development, the advancement in molecular biology, and the invention of many innovative therapies. Immunotherapy partially accounts for this advance, since it is increasingly playing an important role in the treatmen...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735419827090
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Vitamin D supplements may prevent recurrence, prolong survival, and improve mood for women with breast cancer, although evidence for these effects is preliminary. METHODS:This report describes vitamin D supplement use by 553 breast cancer patient/survivors (193 who used a naturopathic oncology [NO] provider...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418822056
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Polysaccharide K, also known as PSK or Krestin, is derived from the Coriolus versicolor mushroom and is widely used in Japan as an adjuvant immunotherapy for a variety of cancer including lung cancer. Despite reported benefits, there has been no English language synthesis of PSK for lung cancer. To address t...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735415572883
更新日期:2015-05-01 00:00:00
abstract::A recurrence of cancer is a traumatic and stressful experience, and a number of approaches have been proposed to manage or treat the associated psychological distress. Meditative techniques such as mindfulness may be able to improve an individual's ability to cope with stressful life events such as cancer diagnosis or...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420908341
更新日期:2020-01-01 00:00:00
abstract::Although localized colon cancer is often successfully treated with surgery, advanced disease requires aggressive systemic therapy that has lower effectiveness. Approximately 30% to 75% of patients with colon cancer use complementary and alternative medicine (CAM), but there is limited formal evidence of survival effic...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735411406539
更新日期:2011-09-01 00:00:00
abstract::Background: Chemotherapy-induced peripheral neuropathy (CIPN) has no cure, but acupuncture may provide relief through its known neuromodulation or neuroendocrine adjustment. This review aimed to assess the efficacy of acupuncture in treating CIPN. Method: A literature review following the PRISMA Statement was performe...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析
doi:10.1177/1534735419886662
更新日期:2019-01-01 00:00:00