Abstract:
AIM:Diagnosis of pleural TB poses serious challenges due to paucibacillary nature of specimens and there is an urgent need to devise a reliable diagnostic test. METHODS:We compared GeneXpert Mycobacterium tuberculosis/rifampin assay and the multiplex PCR (M-PCR) targeting mpb64 (Rv1980c) and IS6110 in pleural fluids (n = 78) of pleural TB patients and non-TB controls. RESULTS:The sensitivities of 89.6 and 33.3%, and specificities of 96.7 and 100%, were observed with M-PCR and Xpert assay, respectively. CONCLUSION:M-PCR showed superiority over Xpert assay and may facilitate an efficient diagnosis of pleural TB.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Sharma S,Dahiya B,Sreenivas V,Singh N,Raj A,Sheoran A,Yadav A,Gupta KB,Mehta PKdoi
10.2217/fmb-2017-0147subject
Has Abstractpub_date
2018-03-01 00:00:00pages
407-413eissn
1746-0913issn
1746-0921journal_volume
13pub_type
杂志文章abstract::The history of vaccines for respiratory syncytial virus (RSV) illustrates the complex immunity and immunopathology to this ubiquitous virus, starting from the failed formalin-inactivated vaccine trials performed in the 1960s. An attractive alternative to traditional live or killed virus vaccines is a defined vaccine c...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.22
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.77
更新日期:2010-08-01 00:00:00
abstract::Aim: In an Emergency Department (ED), the etiological identification of infected subjects is essential. 13 infection-related biomarkers were assessed using a new flow cytometry procedure. Materials & methods: If subjects presented with febrile symptoms at the ED, 13 biomarkers' levels, including CD64 on neutrophils (n...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0256
更新日期:2020-02-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.61
更新日期:2015-01-01 00:00:00
abstract::The outstanding ability of Acinetobacter baumannii to cause outbreaks and acquire multidrug resistance motivated the development of a plethora of typing techniques, which can help infection preventionists and hospital epidemiologists to more efficiently implement intervention controls. Nowadays, the world is witnessin...
journal_title:Future microbiology
pub_type: 杂志文章,评审
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.144
更新日期:2016-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 评论,杂志文章
doi:10.2217/fmb.12.12
更新日期:2012-04-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0275
更新日期:2020-07-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.46
更新日期:2015-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 面试
doi:10.2217/fmb-2019-0016
更新日期:2019-03-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.13.98
更新日期:2013-10-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0082
更新日期:2018-09-01 00:00:00
abstract:AIM:To understand the relationship between ica, aap and bhp gene expression and the implications in biofilm formation in selected clinical and commensal Staphylococcus epidermidis isolates. MATERIAL & METHODS:Isolates were analyzed regarding their biofilm-forming capacity, biochemical matrix composition, biofilm spati...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0140
更新日期:2018-03-01 00:00:00
abstract::The term 'neglected tropical diseases' predominantly refers to single-entity, mostly parasitic diseases. However, a considerable morbidity and mortality burden is carried by patients infected with Gram-positive cocci and Gram-negative bacilli that are prevalent all over the world, yet have impact in tropical and devel...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.12.126
更新日期:2013-01-01 00:00:00
abstract::Gallium has a long history as a diagnostic and chemotherapeutic agent. The pharmacological properties of Ga(III) rely on chemical mimicry; when Ga(III) is exogenously supplied to living cells it can replace Fe(III) within target molecules, thereby perturbing bacterial metabolism. Ga(III)-induced metabolic distresses a...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.14.3
更新日期:2014-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.144
更新日期:2012-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0234
更新日期:2018-12-01 00:00:00
abstract::Inhibitors that target the retroviral enzyme reverse transcriptase (RT) have played an indispensable role in the treatment and prevention of HIV-1 infection. They can be grouped into two distinct therapeutic groups, namely the nucleoside and nucleotide RT inhibitors (NRTIs), and the non-nucleoside RT inhibitors (NNRTI...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.106
更新日期:2015-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.12.134
更新日期:2013-02-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0032
更新日期:2017-09-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2016-0013
更新日期:2016-07-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0167
更新日期:2019-09-01 00:00:00
abstract::Background: Sporotrichosis occurs through contact with contaminated soil and plant. However, the incidence of sporotrichosis as a zoonotic epidemic has increased, particularly in Rio de Janeiro. Aim: In this work, we decided to evaluate some T-cell phenotypes involved in the immune response. Materials & methods: We us...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2020-0046
更新日期:2020-09-01 00:00:00
abstract::Most humans are infected with herpes simplex virus (HSV) type 1 in early childhood and remain latently infected throughout life. While most individuals have mild or no symptoms, some will develop destructive HSV keratitis. Ocular infection with HSV-1 and its associated sequelae account for the majority of corneal blin...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.73
更新日期:2011-08-01 00:00:00
abstract::Background: A major focus of tuberculosis drug discovery is aimed at the development of novel antibiotics with activity against drug-resistant strains of Mycobacterium tuberculosis. Results: We have synthesized ten isoniazid derivatives and investigated for antibacterial activity toward M. tuberculosis H37Rv and isoni...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0085
更新日期:2020-07-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.1.4.387
更新日期:2006-12-01 00:00:00
abstract::Breastfeeding is a major determinant of human health. Breast milk is not sterile and ecological large-scale sequencing methods have revealed an unsuspected microbial diversity that plays an important role. However, microbiological analysis at the species level has been neglected while it is a prerequisite before under...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0317
更新日期:2019-05-01 00:00:00
abstract::The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagnostic solutions. A m...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.14.127
更新日期:2015-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0137
更新日期:2017-12-01 00:00:00