Extracellular cholesterol oxidase production by Streptomyces aegyptia, in vitro anticancer activities against rhabdomyosarcoma, breast cancer cell-lines and in vivo apoptosis.

abstract：:Intensive research has been focused on the synthesis of long-lasting SrAl2O4:EuDy in luminescent materials field. Traditionally, SrAl2O4:EuDy is synthesized in bulk form by solid state. However, their development remains restrained due to this technique is not compatible with large-scale production, sustainability and...

journal_title：Scientific reports

authors： Rojas-Hernandez RE,Rubio-Marcos F,Serrano A,Del Campo A,Fernandez JF

更新日期：2017-03-28 00:00:00

abstract：:Aluminum-based quasicrystals typically form across narrow composition ranges within binary to quaternary alloys, which makes their fabrication and characterization challenging. Here, we use combinatorial approaches together with fast characterization techniques to study a wide compositional range including known quasi...

journal_title：Scientific reports

authors： Wolf W,Kube SA,Sohn S,Xie Y,Cha JJ,Scanley BE,Kiminami CS,Bolfarini C,Botta WJ,Schroers J

更新日期：2019-05-09 00:00:00

abstract：:The neuronal accumulation of phosphorylated tau plays a critical role in the pathogenesis of Alzheimer's disease (AD). Here, we examined the effect of fisetin, a flavonol, on tau levels. Treatment of cortical cells or primary neurons with fisetin resulted in significant decreases in the levels of phosphorylated tau. I...

journal_title：Scientific reports

authors： Kim S,Choi KJ,Cho SJ,Yun SM,Jeon JP,Koh YH,Song J,Johnson GV,Jo C

更新日期：2016-04-26 00:00:00

abstract：:Insect pheromones offer potential for managing pests of crop plants. Volatility and instability are problems for deployment in agriculture but could be solved by expressing genes for the biosynthesis of pheromones in the crop plants. This has now been achieved by genetically engineering a hexaploid variety of wheat to...

journal_title：Scientific reports

authors： Bruce TJA,Aradottir GI,Smart LE,Martin JL,Caulfield JC,Doherty A,Sparks CA,Woodcock CM,Birkett MA,Napier JA,Jones HD,Pickett JA

更新日期：2015-06-25 00:00:00

abstract：:Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (MBSR) in reducing menopause-related symptoms by comparing with an active control group, the menopause educatio...

journal_title：Scientific reports

authors： Wong C,Yip BH,Gao T,Lam KYY,Woo DMS,Yip ALK,Chin CY,Tang WPY,Choy MMT,Tsang KWK,Ho SC,Ma HSW,Wong SYS

更新日期：2018-04-26 00:00:00

abstract：:Quantum walks often provide telling insights about the structure of the system on which they are performed. In [Formula: see text]-symmetric and lossy dimer lattices, the topological properties of the band structure manifest themselves in the quantization of the mean displacement of such a walker. We investigate the f...

journal_title：Scientific reports

authors： Harter AK,Saxena A,Joglekar YN

更新日期：2018-08-13 00:00:00

abstract：:Adipose stromal cells (ASC) secrete various trophic factors that assist in the protection of neurons in a variety of neuronal death models. In this study, we tested the effects of human ASC conditional medium (ASC-CM) in human amyotrophic lateral sclerosis (ALS) transgenic mouse model expressing mutant superoxide dism...

journal_title：Scientific reports

authors： Fontanilla CV,Gu H,Liu Q,Zhu TZ,Zhou C,Johnstone BH,March KL,Pascuzzi RM,Farlow MR,Du Y

更新日期：2015-11-20 00:00:00

abstract：:In this article, we experimentally and numerically investigate a planar terahertz metamaterial (MM) geometry capable of exhibiting independently tunable multi-band electromagnetically induced transparency effect (EIT). The MM structure exhibits multi-band EIT effect due to the strong near field coupling between the br...

journal_title：Scientific reports

authors： Sarkar R,Ghindani D,Devi KM,Prabhu SS,Ahmad A,Kumar G

更新日期：2019-12-02 00:00:00

abstract：:Although extensive studies have focused on the development of acute mountain sickness (AMS), the exact mechanisms of AMS are still obscure. In this study, we used isobaric tags for relative and absolute quantitation (iTRAQ) proteomic analysis to identify novel AMS-associated biomarkers in human plasma. After 9 hours o...

journal_title：Scientific reports

authors： Lu H,Wang R,Li W,Xie H,Wang C,Hao Y,Sun Y,Jia Z

更新日期：2018-01-19 00:00:00

abstract：:Soybean is an important source of protein, oil and carbohydrates, as well as other beneficial nutrients. A major function of proteins in nutrition is to supply adequate amounts of amino acids. Although they are essential for human nutrition, the sulfur-containing amino acids cysteine (Cys) and methionine (Met) are oft...

journal_title：Scientific reports

authors： Malle S,Eskandari M,Morrison M,Belzile F

更新日期：2020-12-11 00:00:00

abstract：:Wrist worn raw-data accelerometers are used increasingly in large-scale population research. We examined whether sleep parameters can be estimated from these data in the absence of sleep diaries. Our heuristic algorithm uses the variance in estimated z-axis angle and makes basic assumptions about sleep interruptions. ...

journal_title：Scientific reports

authors： van Hees VT,Sabia S,Jones SE,Wood AR,Anderson KN,Kivimäki M,Frayling TM,Pack AI,Bucan M,Trenell MI,Mazzotti DR,Gehrman PR,Singh-Manoux BA,Weedon MN

更新日期：2018-08-28 00:00:00

abstract：:Pseudomonas aeruginosa is a major threat for immune-compromised patients. Bacterial pneumonia can induce uncontrolled and massive neutrophil recruitment ultimately leading to acute respiratory distress syndrome and epithelium damage. Interleukin-22 plays a central role in the protection of the epithelium. In this stud...

journal_title：Scientific reports

authors： Broquet A,Jacqueline C,Davieau M,Besbes A,Roquilly A,Martin J,Caillon J,Dumoutier L,Renauld JC,Heslan M,Josien R,Asehnoune K

更新日期：2017-09-08 00:00:00

abstract：:Altering mechanical compliance in load carriage structures has shown to reduce metabolic cost and accelerative forces of carrying weight. Currently, modifications to load carriage structures have been primarily targeted at vertical motion of the carried mass. No study to date has investigated altering load carriage co...

journal_title：Scientific reports

authors： Martin JP,Li Q

更新日期：2018-09-13 00:00:00

abstract：:Antibodies of the IgG class to terminal Galα3Gal (IgG anti-αGal) is abundant in human plasma and are reported to bind most sepsis-causing Gram-negative bacteria. However, these seminal findings, made more than two decades ago, have not been reexamined. Our aim was to assess IgG anti-αGal´s pathogen reactivity. We affi...

journal_title：Scientific reports

authors： Bernth Jensen JM,Petersen MS,Ellerman-Eriksen S,Møller BK,Jensenius JC,Sørensen UBS,Thiel S

更新日期：2020-03-12 00:00:00

abstract：:There are three sex ratio strategies (SRS) in nature-male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton's local mate competition (LMC) and Clark's local resource compe...

journal_title：Scientific reports

authors： Wang Y,Wang R,Li Y,Sam Ma Z

更新日期：2016-12-23 00:00:00

abstract：:Invasive motor Cortex Stimulation (iMCS) was introduced in the 1990's for the treatment of chronic neuropathic orofacial pain (CNOP), although its effectiveness remains doubtful. However, CNOP is known to be a heterogeneous group of orofacial pain disorders, which can lead to different responses to iMCS. Therefore, th...

journal_title：Scientific reports

authors： Henssen D,Kurt E,van Walsum AVC,Kozicz T,van Dongen R,Bartels R

更新日期：2020-04-28 00:00:00

abstract：:Hypocotyl elongation is considered an important typical seedling trait contributing directly to an increase in and stabilization of the yield in Brassica napus, but its molecular genetic mechanism is poorly understood. In the present study, hypocotyl lengths of 210 lines were measured in an illuminated culture room. A...

journal_title：Scientific reports

authors： Luo X,Xue Z,Ma C,Hu K,Zeng Z,Dou S,Tu J,Shen J,Yi B,Fu T

更新日期：2017-01-31 00:00:00

abstract：:Genetic divergences among mammalian strains are presented phenotypically in various aspects of physical appearance such as body shape and facial features. Yet how genetic diversity is expressed in brain function still remains unclear. Functional connectivity has been shown to be a valuable approach in characterizing t...

journal_title：Scientific reports

authors： Huang SM,Wu YL,Peng SL,Peng HH,Huang TY,Ho KC,Wang FN

更新日期：2016-02-22 00:00:00

abstract：:Oysters are unusual among bivalves in that they possess chambers, often filled with soft, chalky calcite, that are irregularly scattered throughout the shell. Because the function of these so-called chalky deposits is still unclear, evaluating the growth and distribution of chalk is important for elucidating the ecolo...

journal_title：Scientific reports

authors： Banker RMW,Sumner DY

更新日期：2020-07-21 00:00:00

abstract：:Accurate and detailed knowledge of California's groundwater is of paramount importance for statewide water resources planning and management, and to sustain a multi-billion-dollar agriculture industry during prolonged droughts. In this study, we use water supply and demand information from California's Department of W...

journal_title：Scientific reports

authors： Massoud EC,Purdy AJ,Miro ME,Famiglietti JS

更新日期：2018-08-27 00:00:00

abstract：:The malaria vaccine BK-SE36 is a recombinant protein (SE36) based on the Honduras 1 serine repeat antigen-5 of Plasmodium falciparum, adsorbed to aluminium hydroxide gel. The phase Ib trial in Uganda demonstrated the safety and immunogenicity of BK-SE36. Ancillary analysis in the follow-up study of 6-20 year-old volun...

journal_title：Scientific reports

authors： Yagi M,Palacpac NM,Ito K,Oishi Y,Itagaki S,Balikagala B,Ntege EH,Yeka A,Kanoi BN,Katuro O,Shirai H,Fukushima W,Hirota Y,Egwang TG,Horii T

更新日期：2016-10-05 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are glutamate- and glycine-gated channels composed of two GluN1 and two GluN2 or/and GluN3 subunits. GluN3A expression is developmentally regulated, and changes in this normal pattern of expression, which occur in several brain disorders, alter synaptic maturation and function by ...

journal_title：Scientific reports

authors： Cummings KA,Popescu GK

更新日期：2016-03-22 00:00:00

abstract：:Foliar fungi of silver birch (Betula pendula) in an experimental Finnish forest were investigated across a gradient of tree species richness using molecular high-throughput sequencing and visual macroscopic assessment. We hypothesized that the molecular approach detects more fungal taxa than visual assessment, and tha...

journal_title：Scientific reports

authors： Nguyen D,Boberg J,Cleary M,Bruelheide H,Hönig L,Koricheva J,Stenlid J

更新日期：2017-02-02 00:00:00

abstract：:Threat detection is essential for protecting individuals from adverse situations, in which a network of amygdala, limbic regions and dorsomedial prefrontal cortex (dmPFC) regions are involved in fear processing. Excitability regulation in the dmPFC might be crucial for fear processing, while abnormal patterns could le...

journal_title：Scientific reports

authors： Gonzalez-Escamilla G,Chirumamilla VC,Meyer B,Bonertz T,von Grotthus S,Vogt J,Stroh A,Horstmann JP,Tüscher O,Kalisch R,Muthuraman M,Groppa S

更新日期：2018-09-28 00:00:00

abstract：:Low level light therapy receives increasing interest in the fields of tissue regeneration and wound healing. Several in vivo studies demonstrated the positive effects of LLLT on angiogenesis. This study aimed to investigate the underlying properties in vitro by comparing the effects of light therapy by light emitting ...

journal_title：Scientific reports

authors： Rohringer S,Holnthoner W,Chaudary S,Slezak P,Priglinger E,Strassl M,Pill K,Mühleder S,Redl H,Dungel P

更新日期：2017-09-06 00:00:00

abstract：:We report the counterintuitive mechanism of increasing boiling heat transfer by incorporating low-conductivity materials at the interface between the surface and fluid. By embedding an array of non-conductive lines into a high-conductivity substrate, in-plane variations in the local surface temperature are created. Du...

journal_title：Scientific reports

authors： Rahman MM,Pollack J,McCarthy M

更新日期：2015-08-18 00:00:00

abstract：:In this study we present an image analysis methodology capable of quantifying morphological changes in tissue collagen fibril organization caused by pathological conditions. Texture analysis based on first-order statistics (FOS) and second-order statistics such as gray level co-occurrence matrix (GLCM) was explored to...

journal_title：Scientific reports

authors： Mostaço-Guidolin LB,Ko AC,Wang F,Xiang B,Hewko M,Tian G,Major A,Shiomi M,Sowa MG

更新日期：2013-01-01 00:00:00

abstract：:Leishmaniasis is a Neglected Tropical Disease caused by the insect-vector borne protozoan parasite, Leishmania species. Infection affects millions of the world's poorest, however vaccines are absent and drug therapy limited. Recently, public-private partnerships have developed to identify new modes of controlling leis...

journal_title：Scientific reports

authors： Norcliffe JL,Mina JG,Alvarez E,Cantizani J,de Dios-Anton F,Colmenarejo G,Valle SG,Marco M,Fiandor JM,Martin JJ,Steel PG,Denny PW

更新日期：2018-03-02 00:00:00

abstract：:Technical advances including liquid chromatography-tandem mass spectrometry and its data analysis enable detailed proteomic analysis of the nasal mucus. Alterations of the nasal mucus proteome may provoke substantial changes of the nasal physiology and have already been associated with rhinologic diseases such as alle...

journal_title：Scientific reports

authors： Wolf A,Liesinger L,Spoerk S,Schittmayer M,Lang-Loidolt D,Birner-Gruenberger R,Tomazic PV

更新日期：2018-12-03 00:00:00

abstract：:Coastal wetlands are important carbon sinks globally, but their ability to store carbon hinges on their nitrogen (N) supply and N uptake dynamics of dominant plant species. In terrestrial ecosystems, uptake of nitrate (NO3-) and ammonium (NH4+) through roots can strongly influence N acquisition rates and their respons...

journal_title：Scientific reports

authors： Cott GM,Caplan JS,Mozdzer TJ

更新日期：2018-03-29 00:00:00