Abstract:
:Nausea and vomiting are among the most common and distressing side effects of chemotherapy. Additional antiemetic drugs are urgently needed to effectively manage and ameliorate chemotherapy-induced nausea and vomiting (CINV). The efficacy of ginger as an antiemetic modality for ameliorating CINV has not been established in previous studies. The aim of this study was to examine the efficacy of ginger, as an adjuvant drug to standard antiemetic therapy, in ameliorating acute and delayed CINV in patients with lung cancer receiving cisplatin-based regimens. In this randomized, double-blind, placebo-controlled clinical trial, 140 patients with lung cancer receiving cisplatin-based regimens were enrolled and allocated to receive either ginger root powder or a placebo. Ginger root powder was administered orally (0.5 g, 2 capsules per day, 0.25 g per capsule, every 12 hours) for 5 days beginning on the first day of chemotherapy. The incidence and severity of acute and delayed nausea and vomiting were assessed using the MASCC (Multinational Association for Supportive Care in Cancer) Antiemesis Tool (MAT). Adverse effects and patient adherence were also assessed in this study. No significant difference was observed between the ginger and control groups in the reduction of the incidence and severity of nausea and vomiting ( P > .05). No significant difference in adverse events was observed between the 2 groups ( P > .05). No study-treatment-related adverse events were observed in this study. As an adjuvant drug to standard antiemetic therapy, ginger had no additional efficacy in ameliorating CINV in patients with lung cancer receiving cisplatin-based regimens.
journal_name
Integr Cancer Therjournal_title
Integrative cancer therapiesauthors
Li X,Qin Y,Liu W,Zhou XY,Li YN,Wang LYdoi
10.1177/1534735417753541subject
Has Abstractpub_date
2018-09-01 00:00:00pages
747-754issue
3eissn
1534-7354issn
1552-695Xjournal_volume
17pub_type
杂志文章,随机对照试验abstract::Studies show an important relationship between vitamin D and malignancies, both in prevention and treatment. The extraskeletal actions of vitamin D relevant to oncology include being proapoptotic, antimetastatic, antiangiogenic, antiinflammatory, prodifferentiating, and immunomodulating. Widespread and severe vitamin ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735408319062
更新日期:2008-06-01 00:00:00
abstract::Plants from the Bursera genus are widely distributed in the tropical dry forests of Mexico. In traditional medicine, extracts from different species of Bursera have been used for a wide range of biological activities, including the treatment of cancer-related symptoms. Compounds present in the Bursera genus include li...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418766416
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There is a lack of information on therapies recommended by naturopathic doctors (NDs) for lung and gastroesophageal cancer care. Study objectives were to: (1) identify the most common interventions considered for use by NDs; (2) identify interventions NDs recommend to support key therapeutic g...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418759420
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abstract:BACKGROUND:Malignant pleural effusion (MPE) is a common complication in most malignancies. Despite its frequent occurrence, current knowledge of MPE remains limited and the effect of the management is still unsatisfying. Traditional Chinese medicine (TCM) external treatment has unique advantages, such as quicker effica...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1534735416660193
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Jiedu Sangen Decoction (JSD), a traditional Chinese medicine formula, has been widely applied in the treatment of gastrointestinal cancer, especially in colorectal cancer. Our study mainly aimed to assess the combined efficacy of Jiedu Sangen aqueous extract (JSAE) and a PD-L1 inhibitor (PI) in colon cancer ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420972486
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:This study aimed to investigate whether the extracellular-to-intracellular fluid volume (E/I) ratio can predict survival in patients with metastatic cancer. METHODS:Clinical data were collected from April 2016 to March 2018. Patients aged ≥19 years with metastatic solid tumor were eligible. Bioimpedance analys...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735419847285
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abstract::Purpose: This article discusses the results of an evaluation of the one-year implementation period of an integrative care program at a pediatric oncology ward, which consists of integrative care treatments offered three times a week to the patients. The guiding questions are how the model was implemented, which factor...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420928393
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abstract::Acute doxorubicin (DOX) cardiotoxicity can be attenuated by exercise preconditioning, but little is known of whether this cardioprotection continues beyond 10 days post-DOX administration. The purpose of this study was to determine the effects of exercise preconditioning on early chronic DOX-induced cardiotoxicity. Ma...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735410392577
更新日期:2011-03-01 00:00:00
abstract::Chronic inflammation may be a causative factor in breast cancer. One possible underlying mechanism is the generation of oxidative stress, which may favor tumorigenic processes. Antioxidant consumption may, therefore, help reduce tissue inflammation levels. However, few studies have explored this relation in breast tis...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
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abstract:BACKGROUND:Because of advances in medical treatment, the survival of cancer patients is prolonged. In line with the prolonged survival time of cancer the incidence of second primary cancer has increased. There is currently no effective way to prevent the occurrence of secondary primary cancer (SPC). OBJECTIVES:The aim...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735419834353
更新日期:2019-01-01 00:00:00
abstract::The protective effect of Andrograhis paniculata and andrographolide (ANDLE) against cyclophosphamide (CTX)-induced urothelial toxicity was investigated in this study. Pretreatment of Swiss albino mice with A paniculata extract (10 mg/dose/animal intraperitoneally [ip]) and ANDLE (500 microg/dose/animal ip) could signi...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735406291984
更新日期:2006-09-01 00:00:00
abstract::Background The role of whole grains, refined cereals, and legumes in preventing or initiating colorectal cancer (CRC) is still uncertain. The aim of this study is to examine the possible association between the consumption of whole grains, refined cereals, and legumes and the risk of developing CRC among Jordanian pop...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735415620010
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Melatonin (MLT) is known to possess potent antioxidant, antiproliferative, immune-modulating, and hormone-modulating properties. Clinical evidence suggests that MLT may have a possible role in the treatment of cancer. The authors systematically reviewed the effects of MLT in conjunction with chemotherapy, ra...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析,评审
doi:10.1177/1534735411425484
更新日期:2012-12-01 00:00:00
abstract::Background: Chemotherapy-induced peripheral neuropathy (CIPN) has no cure, but acupuncture may provide relief through its known neuromodulation or neuroendocrine adjustment. This review aimed to assess the efficacy of acupuncture in treating CIPN. Method: A literature review following the PRISMA Statement was performe...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析
doi:10.1177/1534735419886662
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:High-grade gliomas are the most common and invasive malignant brain tumors in adults, and they are almost universally fatal because of drug resistance and recurrence. In spite of the progress in adjuvant therapy (like temozolomide) and irradiation after surgery, no effective salvage therapy is currently avai...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735414549623
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:This study portrays the characteristics of patients who attended an integrative oncology clinic at a large comprehensive cancer center and evaluated whether this service addressed patients' concerns about complementary and integrative medicine (CIM). METHODS:Patient information was collected prior to an int...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735410378663
更新日期:2010-09-01 00:00:00
abstract::Recent advances in cancer detection and treatment have resulted in an increase in the survival rate of individuals diagnosed with cancer. The increased survival rate brings new challenges for increasing the quality of life for cancer survivors. Debilitating side effects can result from the cancer itself and the cancer...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/153473540200100117
更新日期:2002-03-01 00:00:00
abstract::Gastric cancer (GC) is a malignancy with few effective treatment options after metastasis occurs. Quercetin (Qu) intake has been associated with reduced incidence and slow development of GC, probably due to its anti-proliferative and apoptotic effects, but it is unclear whether Qu can inhibit the metastatic activity. ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735417696702
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Due to the limitations and side effects of conventional cancer treatment, especially in relation to quality of life (QOL), patients are increasingly utilizing complementary and alternative medicine (CAM) to supplement health-related outcomes. However, evidence for the safety and efficacy of such treatments i...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735411413268
更新日期:2012-06-01 00:00:00
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journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418820444
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of participating in an integrative cancer care program at the Centre for Integrated Healing in Vancouver, British Columbia, on patients' lifestyle, quality of life, and overall well-being. STUDY DESIGN:A mixed-methods case study with a pre- and posttest design. No control group was uti...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735407313395
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abstract::Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that tends to affect young women and has a high propensity to metastasize. No targeted treatments are available for this type of breast cancer due to a lack of estrogen or progesterone receptors or overexpression of human epidermal growth f...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735420917444
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journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735405275648
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:Essential thrombocythemia, polycythemia vera, and myelofibrosis are rare chronic hematological malignancies known as myeloproliferative neoplasms (MPNs) and are characterized by deregulated myeloid lineage cell production, splenomegaly, and heterogeneous symptom profiles. MPN patients suffer from a significant ...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735416661417
更新日期:2017-12-01 00:00:00
abstract::Cancers involving the oral cavity, head, and neck regions are often treated with cisplatin. In cancer therapy, the main target is to eliminate unwanted cancerous cells. However, reports on the nonselective nature of this drug have raised few concerns. Incorrect nutritional habits and lifestyle practices have been dire...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735416675950
更新日期:2017-09-01 00:00:00
abstract::Different vitamins and other micronutrients in vegetables, fruits, and other natural plant products may prevent cancer development (carcinogenesis) by interfering with detrimental actions of mutagens, carcinogens, and tumor promoters. The goal of current studies in cancer prevention is to determine the mechanisms of s...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,评审
doi:10.1177/1534735403002002005
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Chemoradiotherapy-associated mucositis can manifest as pain, inflammation, dysphagia, diarrhea, weight loss, rectal bleeding, and infection. Mucositis is a major dose-limiting side effect of chemotherapy, affecting nutritional intake and oral and intestinal function. Despite several interventions being avail...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418794885
更新日期:2018-12-01 00:00:00
abstract::Physical inactivity is a major concern in cancer patients despite the established preventative and therapeutic effects of regular physical exercise for this patient group. Sport not only plays an important role in supporting the development and maintenance of a physically active lifestyle but also is increasingly used...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
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abstract::The effectiveness of traditional herbal medicine (THM) as treatment for nasopharyngeal cancer (NPC) has not been clearly demonstrated. The aim of this study is to assess the effectiveness of THM as adjunctive therapies for NPC using the results of randomized controlled trials (RCTs). Five electronic databases, includi...
journal_title:Integrative cancer therapies
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Vitamin D supplements may prevent recurrence, prolong survival, and improve mood for women with breast cancer, although evidence for these effects is preliminary. METHODS:This report describes vitamin D supplement use by 553 breast cancer patient/survivors (193 who used a naturopathic oncology [NO] provider...
journal_title:Integrative cancer therapies
pub_type: 杂志文章
doi:10.1177/1534735418822056
更新日期:2019-01-01 00:00:00