Exploring an optimal wavelet-based filter for cryo-ET imaging.

abstract：:The pine wood nematode, Bursaphelenchus xylophilus, is the causal agent of pine wilt disease that has devastated pine forests in Asia. Parasitic nematodes are known to have evolved antioxidant stress responses that defend against host plant defenses. In this study, the infestation of whitebark pine, Pinus bungean, wit...

journal_title：Scientific reports

authors： Li Z,Zhang Q,Zhou X

更新日期：2016-06-07 00:00:00

abstract：:The stress reactivity hypothesis posits that the magnitude of cardiovascular reactions to acute stress tasks is related with future blood pressure status, heart hypertrophy, and atherosclerosis. We assessed the stress reactivity hypothesis and aimed to identify which physiological indices (blood pressure, heart-rate, ...

journal_title：Scientific reports

authors： Wright BJ,O'Brien S,Hazi A,Kent S

更新日期：2014-11-13 00:00:00

abstract：:Hypoxia-inducible transcription factors (HIF) form heterodimeric complexes that mediate cell responses to hypoxia. The oxygen-dependent stability and activity of the HIF-α subunits is traditionally associated to post-translational modifications such as hydroxylation, acetylation, ubiquitination, and phosphorylation. H...

journal_title：Scientific reports

authors： Fala AM,Oliveira JF,Adamoski D,Aricetti JA,Dias MM,Dias MVB,Sforça ML,Lopes-de-Oliveira PS,Rocco SA,Caldana C,Dias SMG,Ambrosio ALB

更新日期：2015-08-03 00:00:00

abstract：:Jellyfish stingings are currently raising serious public health concerns around the world. Hence, the search for an effective first aid reagent for the envenomation has been the goal of many investigators in the field. There have been a few previous reports of in vivo as well as in vivo studies suggesting the metallop...

journal_title：Scientific reports

authors： Hwang DH,Lee H,Choudhary I,Kang C,Chae J,Kim E

更新日期：2020-10-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Azmi K,Al-Jawabreh A,Abdeen Z

更新日期：2020-02-05 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Bebber DP,Butt N

更新日期：2018-10-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) plays an important role on fibrogenesis in heart disease. MicroRNAs have exhibited as crucial regulators of cardiac homeostasis and remodeling in various heart diseases. MiR-19a-3p/19b-3p expresses with low levels in the plasma of heart failure patients. The purpose of our study ...

journal_title：Scientific reports

authors： Zou M,Wang F,Gao R,Wu J,Ou Y,Chen X,Wang T,Zhou X,Zhu W,Li P,Qi LW,Jiang T,Wang W,Li C,Chen J,He Q,Chen Y

更新日期：2016-04-21 00:00:00

abstract：:Due to their small dimensions, electrophysiology on thin and intricate axonal branches in support of understanding their role in normal and diseased brain function poses experimental challenges. To reduce experimental complexity, we coupled microelectrode arrays (MEAs) to bi-level microchannel devices for the long-ter...

journal_title：Scientific reports

authors： Habibey R,Latifi S,Mousavi H,Pesce M,Arab-Tehrany E,Blau A

更新日期：2017-08-17 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) affects over 30% of adults in the United States. Bone morphogenetic protein (BMP) signaling is known to contribute to hepatic fibrosis, but the role of BMP signaling in the development of NAFLD is unclear. In this study, treatment with either of two BMP inhibitors reduced hepa...

journal_title：Scientific reports

authors： Thayer TE,Lino Cardenas CL,Martyn T,Nicholson CJ,Traeger L,Wunderer F,Slocum C,Sigurslid H,Shakartzi HR,O'Rourke C,Shelton G,Buswell MD,Barnes H,Neitzel LR,Ledsky CD,Li JP,Burke MF,Farber-Eger E,Perrien DS,Kumar R,

更新日期：2020-06-19 00:00:00

abstract：:Soluble microbial products (SMPs) are of significant concern in the natural environment and in engineered systems. In this work, poly-γ-glutamic acid (γ-PGA), which is predominantly produced by Bacillus sp., was investigated in terms of pH-induced conformational changes and molecular interactions in aqueous solutions;...

journal_title：Scientific reports

authors： Wang LL,Chen JT,Wang LF,Wu S,Zhang GZ,Yu HQ,Ye XD,Shi QS

更新日期：2017-10-06 00:00:00

abstract：:Perilla frutescens (L.) is an important medicinal and edible plant in China with nutritional and medical uses. The extract from leaves of Perilla frutescens contains flavonoids and volatile oils, which are mainly used in traditional Chinese medicine. In this study, we analyzed the transcriptomic and metabolomic data o...

journal_title：Scientific reports

authors： Jiang T,Guo K,Liu L,Tian W,Xie X,Wen S,Wen C

更新日期：2020-10-01 00:00:00

abstract：:Identification of nodal metastasis and tumor extranodal extension (ENE) is crucial for head and neck cancer management, but currently only can be diagnosed via postoperative pathology. Pretreatment, radiographic identification of ENE, in particular, has proven extremely difficult for clinicians, but would be greatly i...

journal_title：Scientific reports

authors： Kann BH,Aneja S,Loganadane GV,Kelly JR,Smith SM,Decker RH,Yu JB,Park HS,Yarbrough WG,Malhotra A,Burtness BA,Husain ZA

更新日期：2018-09-19 00:00:00

abstract：:The interaction between active element Zr and W damages the W fibers and the interface and decreases the mechanical properties, especially the tensile strength of the W fibers reinforced Zr-based bulk metallic glass composites (BMGCs). From the viewpoint of atomic interaction, the W-Zr interaction can be restrained by...

journal_title：Scientific reports

authors： Li ZK,Fu HM,Sha PF,Zhu ZW,Wang AM,Li H,Zhang HW,Zhang HF,Hu ZQ

更新日期：2015-03-11 00:00:00

abstract：:Heat shock factor-1 (HSF1) protects neurons from death caused by the accumulation of misfolded proteins by stimulating the transcription of genes encoding heat shock proteins (HSPs). This stimulatory action depends on the association of trimeric HSF1 to sequences within HSP gene promoters. However, we recently describ...

journal_title：Scientific reports

authors： Qu Z,Titus ASCLS,Xuan Z,D'Mello SR

更新日期：2018-11-22 00:00:00

abstract：:The concept of multiscale architectured materials is established using composition and grain size gradients. Composition-gradient nanostructured materials are produced from coarse grained interstitial free steels via carburization and high-pressure torsion. Quantitative analyses of the dislocation density using X-ray ...

journal_title：Scientific reports

authors： Kang JY,Kim JG,Park HW,Kim HS

更新日期：2016-05-27 00:00:00

abstract：:In patients with type 1 diabetes mellitus (T1DM), glucose dynamics are influenced by insulin reactions, diet, lifestyle, etc., and characterized by instability and nonlinearity. With the objective of a dependable decision support system for T1DM self-management, we aim to model glucose dynamics using their nonlinear c...

journal_title：Scientific reports

authors： Frandes M,Timar B,Timar R,Lungeanu D

更新日期：2017-07-24 00:00:00

abstract：:To determine levels of change in risk factors for cardiovascular disease among people with and without a previous diagnosis of diabetes from 2007 to 2016 in Iran. Data were obtained from five rounds of the World Health Organization STEPwise approach to Surveillance (STEPS) cross-sectional surveys. Participants were 76...

journal_title：Scientific reports

authors： Malekzadeh H,Lotfaliany M,Ostovar A,Hadaegh F,Azizi F,Yoosefi M,Farzadfar F,Khalili D

更新日期：2020-07-16 00:00:00

abstract：:Follicular bronchiolitis (FB) is a rare interstitial lung disease (ILD) and has been reported in diverse clinical contexts. Six FB patients demonstrated by surgical lung biopsy (SLB) were reviewed between 2009 and 2017 from Nanjing Drum Tower Hospital in China. The average age of subjects was 42 years old (range: 31-5...

journal_title：Scientific reports

authors： Lu J,Ma M,Zhao Q,Meng F,Wang D,Cai H,Cao M

更新日期：2018-05-08 00:00:00

abstract：:Targeted protein degradation (TPD) through a proteasome-dependent pathway induced by heterofunctional small molecules is initiated by the formation of a ternary complex with recruited E3 ligases. This complex formation affects the degradation ability of TPD molecules, and thus we tested for visualization of the intrac...

journal_title：Scientific reports

authors： Kaji T,Koga H,Kuroha M,Akimoto T,Hayata K

更新日期：2020-02-20 00:00:00

abstract：:We demonstrate theoretically that photon-photon attraction can be engineered in the continuum of scattering states for pairs of photons propagating in a hollow-core photonic crystal fiber filled with cold atoms. The atoms are regularly spaced in an optical lattice configuration and the photons are resonantly tuned to ...

journal_title：Scientific reports

authors： Litinskaya M,Tignone E,Pupillo G

更新日期：2016-05-12 00:00:00

abstract：:Graphene plasmonics has become a highlighted research area due to the outstanding properties of deep-subwavelength plasmon excitation, long relaxation time, and electro-optical tunability. Although the giant conductivity of a graphene layer enables the low-dimensional confinement of light, the atomic scale of the laye...

journal_title：Scientific reports

authors： Kim Y,Yu S,Park N

更新日期：2017-02-27 00:00:00

abstract：:Human protein tyrosine phosphatase non-receptor type 4 (PTPN4) has been shown to prevent cell death. The active form of human PTPN4 consists of two globular domains, a PDZ (PSD-95/Dlg/ZO-1) domain and a phosphatase domain, tethered by a flexible linker. Targeting its PDZ domain abrogates this protection and triggers a...

journal_title：Scientific reports

authors： Caillet-Saguy C,Toto A,Guerois R,Maisonneuve P,di Silvio E,Sawyer K,Gianni S,Wolff N

更新日期：2017-08-11 00:00:00

abstract：:Switches in heterogamety are known to occur in both animals and plants. Although plant sex determination systems probably often evolved more recently than those in several well-studied animals, including mammals, and have had less time for switches to occur, we previously detected a switch in heterogamety in the plant...

journal_title：Scientific reports

authors： Balounova V,Gogela R,Cegan R,Cangren P,Zluvova J,Safar J,Kovacova V,Bergero R,Hobza R,Vyskot B,Oxelman B,Charlesworth D,Janousek B

更新日期：2019-01-31 00:00:00

abstract：:Transgenic rice producing insecticidal proteins from Bacillus thuringiensis (Bt) could help protect the plants from damage by lepidopteran pests. However, one concern is the potential of Bt rice to harm non-target natural enemies, which play a vital role in pest control. In the present study, the potential effects of ...

journal_title：Scientific reports

authors： Tian JC,Romeis J,Liu K,Zhang FC,Zheng XS,Xu HX,Chen GH,He XC,Lu ZX

更新日期：2017-08-10 00:00:00

abstract：:Artificial tissues constructed from therapeutic cells offer a promising approach for improving the treatment of severe peripheral nerve injuries. In this study the effectiveness of using CTX0E03, a conditionally immortalised human neural stem cell line, as a source of allogeneic cells for constructing living artificia...

journal_title：Scientific reports

authors： O'Rourke C,Day AGE,Murray-Dunning C,Thanabalasundaram L,Cowan J,Stevanato L,Grace N,Cameron G,Drake RAL,Sinden J,Phillips JB

更新日期：2018-02-13 00:00:00

abstract：:Xenotransplantation of human cancers into immunodeficient mice is a very useful approach for studying human tumor biology. However, the occasional occurrence of lymphomagenesis in some mice can spoil the model and must be investigated in detail. We found that a high percentage (32.5%, 26/80) of cancer patient-derived ...

journal_title：Scientific reports

authors： Zhang L,Liu Y,Wang X,Tang Z,Li S,Hu Y,Zong X,Wu X,Bu Z,Wu A,Li Z,Li Z,Huang X,Jia L,Kang Q,Liu Y,Sutton D,Wang L,Luo L,Ji J

更新日期：2015-03-30 00:00:00

abstract：:The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a surrogate of bacterial load), MTB/RIF TB-specific and internal positive control (IPC)-specific C(T) values, and clinical characteristics in ...

journal_title：Scientific reports

authors： Theron G,Peter J,Calligaro G,Meldau R,Hanrahan C,Khalfey H,Matinyenya B,Muchinga T,Smith L,Pandie S,Lenders L,Patel V,Mayosi BM,Dheda K

更新日期：2014-07-11 00:00:00

abstract：:Risk stratification is crucial in prevention. Circulating microRNAs have been proposed as biomarkers in cardiovascular disease. Here a miR panel consisting of miRs related to different cardiovascular pathophysiologies, was evaluated to predict outcome in the context of prevention. MiR-34a, miR-223, miR-378, miR-499 an...

journal_title：Scientific reports

authors： Keller T,Boeckel JN,Groß S,Klotsche J,Palapies L,Leistner D,Pieper L,Stalla GK,Lehnert H,Silber S,Pittrow D,Maerz W,Dörr M,Wittchen HU,Baumeister SE,Völker U,Felix SB,Dimmeler S,Zeiher AM

更新日期：2017-07-03 00:00:00

abstract：:Biological hydrogen production is based on activity of specific enzymes called hydrogenases. Hydrogenases are oxygen sensitive metalloenzymes containing Ni and/or Fe atoms at the active site, catalyzing reversible reduction of protons. Generally, [Fe-Fe] hydrogenases prefer proton reduction to molecular hydrogen, a po...

journal_title：Scientific reports

authors： Mangayil R,Karp M,Lamminmäki U,Santala V

更新日期：2016-10-27 00:00:00

abstract：:Older patients, especially those with malignancy, may have an increased risk of pulmonary embolism (PE). However, few studies have evaluated the clinical characteristics and prognosis of older patients. We evaluated the clinical characteristics, prognosis, and risk factors in older patients with lung cancer complicate...

journal_title：Scientific reports

authors： Junjun L,Pei W,Ying Y,Kui S

更新日期：2020-01-27 00:00:00